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- Bauer, HCF, et al.
(author)
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The Scandinavian Sarcoma Group Register
- 1999
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In: Acta orthopaedica Scandinavica. Supplementum. - : Medical Journals Sweden AB. - 0300-8827 .- 0001-6470. ; 70285, s. 41-44, s. 41-44
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Journal article (peer-reviewed)
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| 9. |
- Bauer, HCF
(author)
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Untitled
- 1997
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In: JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME. - : Ovid Technologies (Wolters Kluwer Health). - 0021-9355. ; 79A:10, s. 1591-1592
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Journal article (other academic/artistic)
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- Einarsdottir, H, et al.
(author)
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110 subfascial lipomatous tumors. MR and CT findings versus histopathological diagnosis and cytogenetic analysis
- 1999
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In: Acta radiologica (Stockholm, Sweden : 1987). - : SAGE Publications. - 0284-1851 .- 1600-0455. ; 40:6, s. 603-609
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Journal article (peer-reviewed)abstract
- Purpose: To evaluate whether liposarcoma, atypical lipomatous tumors and lipoma can be differentiated radiologically. Material and Methods: We have retrospectively analyzed CT and/or MR images of 110 subfascial lipomatous lesions. the amount of fat within the tumors was visually graded from the images as: none, 1–75%, 75–95% or 95–100%. the structure of non-fatty tumor components was compared. the images were compared to histopathology and in 37 cases to cytogenetic findings. Results: Only 4 of 20 liposarcomas contained fat. All 4 lesions, histopathologically diagnosed as atypical lipomatous tumors, contained fat but less than 75% of tumor volume. All lesions with more fat than 75% of tumor volume were histologically diagnosed as lipomas. However, one-third of the karyotyped lipomas had ring chromosomes which are considered typical for atypical lipomatous tumors. Conclusion: When a tumor is composed more or less solely of fat, the diagnosis of a lipoma or atypical lipomatous tumor with a phenotype simulating a lipoma can be assumed. When the fat content is less than 75% of the tumor volume or non-fatty nodules are found, biopsies from different tumor components have to be performed to exclude malignancy. When no fat is found, imaging does not help in differentiating lipoma or liposarcoma from other soft tissue tumors.
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| 13. |
- Einarsdottir, H, et al.
(author)
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Accuracy of cytology for diagnosis of lipomatous tumors: comparison with magnetic resonance and computed tomography findings in 175 cases
- 2004
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In: Acta radiologica (Stockholm, Sweden : 1987). - : SAGE Publications. - 0284-1851 .- 1600-0455. ; 45:8, s. 840-846
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Journal article (peer-reviewed)abstract
- Purpose: To assess the value of fine-needle aspiration cytology in the diagnostic work-up of lipomatous tumors of the extremities and trunk, and to identify specific radiological features that could aid in the preoperative evaluation. Material and Methods: 175 patients with subfascial lipomatous tumors who had undergone preoperative magnetic resonance imaging or computed tomography and fine-needle aspiration cytology were studied. The percentage of fat within the lesion was visually graded from the images as: none, 1-75%, 75-95%, or 95-100%. The histological and cytological diagnoses were compared and in discordant cases the radiological images were re-reviewed. Results: There was cytological and histological concordance in 96% of lipomas and in 85% of atypical lipomatous tumors (ALT) and liposarcomas. Most discordant cases exhibited 1-75% fat. Radiological review suggested that cytological sampling problems due to tumor heterogeneity were the main cause of diagnostic difficulties. The majority of tumors with less than 75% fat were liposarcomas, and in no liposarcoma was the fat content higher than 75%. Both ALT and lipoma were found in the 95-100% group. Conclusion: Cytology can be highly accurate in the diagnosis of lipomatous tumors, including ALT; however, critical comparison with the radiological findings increases diagnostic security. In tumors with fat content visually assessed as less than 75% of the tumor volume, liposarcoma is the most likely diagnosis and a cytological diagnosis of ALT or lipoma should be questioned. In lesions with 75-95% fat, liposarcoma is unlikely, but FNAC is still indicated for safety. In lesions with 95-100% fat, FNAC is only indicated if the differentiation between lipoma and ALT influences the treatment strategy.
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| 14. |
- Einarsdottir, H, et al.
(author)
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Diffusion-weighted MRI of soft tissue tumours
- 2004
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In: European radiology. - : Springer Science and Business Media LLC. - 0938-7994 .- 1432-1084. ; 14:6, s. 959-963
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Journal article (peer-reviewed)
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| 16. |
- Einarsdottir, H, et al.
(author)
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MR imaging of lipoma and liposarcoma
- 1999
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In: Acta radiologica (Stockholm, Sweden : 1987). - : SAGE Publications. - 0284-1851 .- 1600-0455. ; 40:1, s. 64-68
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Journal article (peer-reviewed)abstract
- Purpose: To evaluate whether lipoma, atypical lipomatous tumors, and lipo-sarcomas can be differentiated by MR images. Material and Methods: The MR images of 59 lipomatous lesions and liposarcomas were retrospectively reviewed. Apart from size, surgical site, location and margins, the percentage of fat of the tumor volume was assessed as none, 1-75%, 75-95%, or 95-100%. Results: None of the 18 liposarcomas contained fat that could be recognized by MR imaging. The 3 atypical lipomatous tumors all contained fat but less than 75% of the tumor volume. In 32 of 38 ordinary lipomas, the percentage of fat was 95-100%, and in 4 less than 95% of the tumor volume. Two lipomas did not contain fat that could be recognized by MR imaging. Conclusion: A lesion which predominantly has a fat signal is, in all probability, an ordinary lipoma. Lesions with less fat, but still mostly fatty, may either be lipoma or atypical lipomatous tumor. In this group, the discrimination between these two entities cannot be based upon imaging features. In the absence of a fat signal, liposarcoma or lipoma cannot be differentiated from other soft tissue tumors.
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| 20. |
- Kreicbergs, A, et al.
(author)
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Cytological diagnosis of bone tumours
- 1996
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In: The Journal of bone and joint surgery. British volume. - 0301-620X. ; 78B78:2, s. 258-263
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Journal article (peer-reviewed)
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| 28. |
- Trovik, C., et al.
(author)
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Consequences of local recurrence of soft tissue sarcoma : 205 patients from the Scandinavian Sarcoma Group register
- 2000
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In: Acta Orthopaedica Scandinavica. - 0001-6470. ; 71:5, s. 488-495
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Journal article (peer-reviewed)abstract
- From the Scandinavian Sarcoma Group Register, information on 1,224 surgically-treated patients with soft tissue sarcoma (STS) of the extremity or trunk wall, diagnosed between 1987 and 1995, was collected. 205 patients, one third of whom were referred to a center with a local recurrence, had a total of 284 local recurrences. This analysis describes the treatment for these local recurrences, complications and risk of further recurrences. 169 patients were surgically treated for their first local recurrence. An intralesional or marginal margin was achieved in 110 of these patients, 59 of whom were also given radiotherapy. 54 of the 169 patients had a second local recurrence. The second local recurrence rate was 0.50 if the first local recurrence had been treated with only surgery with a marginal margin, compared to 0.28 if treated with surgery with a marginal margin and radiotherapy or with a wide margin (p = 0.0008). In extremity STS, the crude amputation rate for local recurrences was 0.22 (31 of 142) - i.e., higher than for primary tumors 0.09 (96 of 1065) (p < 0.0001). A high local recurrence rate after treatment outside of sarcoma centers has earlier been shown. We conclude that the consequences of local recurrence in terms of morbidity and costs justifies referral of STS patients for multidisciplinary evaluation and multimodality treatment.
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| 41. |
- Westerberg, L, et al.
(author)
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Untitled - Reply
- 1998
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In: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. - 0281-3432. ; 80A:9, s. 1396-1396
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Journal article (other academic/artistic)
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| 42. |
- Widhe, B, et al.
(author)
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Chest wall chondrosarcoma
- 2009
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In: ACTA ORTHOPAEDICA. - 1745-3674. ; 80, s. 82-84
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Journal article (other academic/artistic)
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