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1.	Aranha, M. R., et al. (author) Basal forebrain atrophy along the Alzheimer's disease continuum in adults with Down syndrome 2023 In: Alzheimers & Dementia. - 1552-5260. ; 19:11, s. 4817-4827 Journal article (peer-reviewed)abstract BackgroundBasal forebrain (BF) degeneration occurs in Down syndrome (DS)-associated Alzheimer's disease (AD). However, the dynamics of BF atrophy with age and disease progression, its impact on cognition, and its relationship with AD biomarkers have not been studied in DS. MethodsWe included 234 adults with DS (150 asymptomatic, 38 prodromal AD, and 46 AD dementia) and 147 euploid controls. BF volumes were extracted from T-weighted magnetic resonance images using a stereotactic atlas in SPM12. We assessed BF volume changes with age and along the clinical AD continuum and their relationship to cognitive performance, cerebrospinal fluid (CSF) and plasma amyloid/tau/neurodegeneration biomarkers, and hippocampal volume. ResultsIn DS, BF volumes decreased with age and along the clinical AD continuum and significantly correlated with amyloid, tau, and neurofilament light chain changes in CSF and plasma, hippocampal volume, and cognitive performance. DiscussionBF atrophy is a potentially valuable neuroimaging biomarker of AD-related cholinergic neurodegeneration in DS.
2.	Camilleri, M, et al. (author) Genetic susceptibility to inflammation and colonic transit in lower functional gastrointestinal disorders: preliminary analysis 2011 In: Neurogastroenterology and motility. - : Wiley. - 1365-2982 .- 1350-1925. ; 23:10, s. 935-E398 Journal article (peer-reviewed)
3.	Camilleri, M, et al. (author) Neuropeptide S receptor induces neuropeptide expression and associates with intermediate phenotypes of functional gastrointestinal disorders 2010 In: Gastroenterology. - : Elsevier BV. - 1528-0012 .- 0016-5085. ; 138:1, s. 98-107 Journal article (peer-reviewed)

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Type of publication: journal article (3)

Type of content: peer-reviewed (3)

Author/Editor: Carlson, P. (2); D'Amato, M (2); Zucchelli, M (2); Camilleri, M (2); MCKINZIE, S (2); Busciglio, I (2); show more...; Burton, D (2); Zinsmeister, AR (2); Blennow, Kaj, 1958 (1); Zetterberg, Henrik, ... (1); Bargallo, N (1); Padilla, C (1); Fernandez, S (1); Alcolea, D. (1); Barroeta, I. (1); Carmona-Iragui, M. (1); Altuna, M. (1); Videla, L. (1); Valldeneu, S. (1); Pegueroles, J. (1); Blesa, R. (1); Fortea, J. (1); Lleó, A. (1); Aranha, M. R. (1); Iulita, M. F. (1); Montal, V. (1); Bejanin, A. (1); Vaque-Alcazar, L. (1); Grothe, M. J. (1); Benejam, B. (1); Arranz, J. (1); Ribas, L. (1); Valle-Tamayo, N. (1); Gonzalez-Ortiz, S. (1); Wisniewski, T. (1); Busciglio, J. (1); Cuello, A. C. (1); show less...

University: Karolinska Institutet (2); University of Gothenburg (1)

Language: English (3)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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