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1.	Bock, K, et al. (author) Effect of population-based screening on breast cancer mortality 2011 In: Lancet (London, England). - 1474-547X. ; 378:9805, s. 1775-1776 Journal article (other academic/artistic)
2.	Hansson, Elisabeth K, 1954, et al. (author) Patients with unilateral transfemoral amputation treated with a percutaneous osseointegrated prosthesis. A cost-effectiveness analysis 2018 In: Bone and Joint Journal. - 2049-4394. ; 100-B:4, s. 527-534 Journal article (peer-reviewed)abstract Aims: The aim of this study was to compare the cost-effectiveness of treatment with an osseointegrated percutaneous (OI-) prosthesis and a socket-suspended (S-) prosthesis for patients with a transfemoral amputation. Patients and Methods: A Markov model was developed to estimate the medical costs and changes in quality-adjusted life-years (QALYs) attributable to treatment of unilateral transfemoral amputation over a projected period of 20 years from a healthcare perspective. Data were collected alongside a prospective clinical study of 51 patients followed for two years. Results: OI-prostheses had an incremental cost per QALY gained of €83 374 compared with S-prostheses. The clinical improvement seen with OI-prostheses was reflected in QALYs gained. Results: were most sensitive to the utility value for both treatment arms. The impact of an annual decline in utility values of 1%, 2%, and 3%, for patients with S-prostheses resulted in a cost per QALY gained of €37 020, €24 662, and €18 952, respectively, over 20 years. Conclusion: From a healthcare perspective, treatment with an OI-prosthesis results in improved quality of life at a relatively high cost compared with that for S-prosthesis. When patients treated with S-prostheses had a decline in quality of life over time, the cost per QALY gained by OI-prosthesis treatment was considerably reduced.

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Type of publication: journal article (2)

Type of content: other academic/artistic (1); peer-reviewed (1)

Author/Editor: Muller, J. (1); Ursin, G (1); Patnick, J (1); Jones, F (1); Frigerio, A. (1); Tornberg, S. (1); show more...; Zappa, M. (1); Holland, R (1); Hagberg, Kerstin, 19 ... (1); Del Turco, MR (1); Heindel, W. (1); Bock, K (1); Borisch, B (1); Cawson, J (1); Damtjernhaug, B (1); de Wolf, C (1); Dean, P (1); den Heeten, A (1); Doyle, G (1); Fox, R (1); Gilbert, F (1); Hecht, G (1); Heywang-Kobrunner, S ... (1); Lernevall, A (1); Madai, S (1); Mairs, A (1); Nisbet, P (1); O'Doherty, A (1); Perry, N (1); Regitz-Jedermann, L (1); Rickard, M (1); Rodrigues, V (1); Scharpantgen, A (1); Schwartz, W (1); Seradour, B (1); Skaane, P (1); Tabar, L (1); Van Limbergen, E (1); Vandenbroucke, A (1); Warren, LJ (1); Warwick, L (1); Yaffe, M (1); Hansson, Elisabeth K ... (1); Brodtkorb, T. H. (1); Cawson, M. (1); show less...

University: University of Gothenburg (1); Karolinska Institutet (1)

Language: English (2)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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