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1.	Hemelaar, J, et al. (author) Global and regional molecular epidemiology of HIV-1, 1990-2015: a systematic review, global survey, and trend analysis 2019 In: The Lancet. Infectious diseases. - 1474-4457. ; 19:2, s. 143-155 Journal article (peer-reviewed)
2.	Berard, AR, et al. (author) Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling 2023 In: Cell reports. - 2211-1247. ; 42:5, s. 112474- Journal article (peer-reviewed)
3.	Koelle, D. M., et al. (author) Worldwide circulation of HSV-2 x HSV-1 recombinant strains 2017 In: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 7 Journal article (peer-reviewed)abstract Homo sapiens harbor two distinct, medically significant species of simplexviruses, herpes simplex virus (HSV)-1 and HSV-2, with estimated divergence 6-8 million years ago (MYA). Unexpectedly, we found that circulating HSV-2 strains can contain HSV-1 DNA segments in three distinct genes. Using over 150 genital swabs from North and South America and Africa, we detected recombinantsworldwide. Common, widely distributed gene UL39 genotypes are parsimoniously explained by an initial >457 basepair (bp) HSV-1 x HSV-2 crossover followed by back-recombination to HSV-2. Blocks of >244 and >539 bp of HSV-1 DNA within genes UL29 and UL30, respectively, have reached near fixation, with a minority of strains retaining sequences we posit as ancestral HSV-2. Our data add to previous in vitroand animal work, implying that in vivo cellular co-infection with HSV-1 and HSV-2 yields viable interspecies recombinants in the natural human host.
4.	Campbell, MS, et al. (author) Viral linkage in HIV-1 seroconverters and their partners in an HIV-1 prevention clinical trial 2011 In: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 6:3, s. e16986- Journal article (peer-reviewed)

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Type of publication: journal article (4)

Type of content: peer-reviewed (4)

Author/Editor: Leitner, T (2); Albert, J. (1); Thomson, M. (1); Zhang, R. (1); Ito, M (1); Gao, F. (1); show more...; Campbell, M. (1); Lara, C. (1); Sorensen, S. (1); Sandstrom, P. (1); Wallace, L. (1); Kaleebu, P (1); Buonaguro, L (1); Salem, H (1); Williams, B (1); Carr, J. (1); Levy, C. (1); Vercauteren, J (1); Grossman, Z (1); Hamouda, O (1); Kostrikis, LG (1); Kucherer, C (1); Liitsola, K (1); Linka, M (1); Vandamme, AM (1); Mhalu, F (1); Urassa, W (1); Cooper, D (1); Williamson, C (1); Papa, A (1); He, X (1); Tran, T (1); Charles, M (1); Jing, L (1); Pillay, D (1); Mullins, J (1); Xie, H (1); Zhao, H (1); Pelletier, A (1); Garcia, F. (1); Ghys, PD (1); Mor, O (1); van Sighem, A (1); Hunt, G (1); Bertagnolio, S (1); Brooks, J (1); Birse, K (1); Lauffenburger, DA (1); Delgado, E (1); Stewart, D (1); show less...

University: Karolinska Institutet (3); University of Gothenburg (1)

Language: English (4)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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