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1.	Galluzzi, L, et al. (author) Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 2018 In: Cell death and differentiation. - : Springer Science and Business Media LLC. - 1476-5403 .- 1350-9047. ; 25:3, s. 486-541 Journal article (peer-reviewed)
2.	Galluzzi, L, et al. (author) Necroptosis: Mechanisms and Relevance to Disease 2017 In: Annual review of pathology. - : Annual Reviews. - 1553-4014. ; 12, s. 103-130 Journal article (peer-reviewed)abstract Necroptosis is a form of regulated cell death that critically depends on receptor-interacting serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL) and generally manifests with morphological features of necrosis. The molecular mechanisms that underlie distinct instances of necroptosis have just begun to emerge. Nonetheless, it has already been shown that necroptosis contributes to cellular demise in various pathophysiological conditions, including viral infection, acute kidney injury, and cardiac ischemia/reperfusion. Moreover, human tumors appear to obtain an advantage from the downregulation of key components of the molecular machinery for necroptosis. Although such an advantage may stem from an increased resistance to adverse microenvironmental conditions, accumulating evidence indicates that necroptosis-deficient cancer cells are poorly immunogenic and hence escape natural and therapy-elicited immunosurveillance. Here, we discuss the molecular mechanisms and relevance to disease of necroptosis.
3.	Vitale, I, et al. (author) Apoptotic cell death in disease-Current understanding of the NCCD 2023 2023 In: Cell death and differentiation. - 1476-5403. ; 30:5, s. 1097-1154 Journal article (peer-reviewed)

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Type of publication: journal article (3)

Type of content: peer-reviewed (3)

Author/Editor: Kroemer, G (3); Kepp, O (3); Galluzzi, L (3); Kumar, S (2); Wang, Y. (2); Kaufmann, T (2); show more...; Pereira, DM (2); Carmona-Gutierrez, D (2); Madeo, F (2); Zhivotovsky, B (2); Meier, P (2); Wood, W (2); Pagano, M (2); Bazan, NG (2); Agostinis, P (2); Simon, HU (2); Klionsky, DJ (2); Penninger, JM (2); Tang, DL (2); Cidlowski, JA (2); Di Virgilio, F (2); Puthalakath, H (2); Strasser, A (2); Piacentini, M (2); Munoz-Pinedo, C. (2); Rehm, M. (2); Altucci, L (2); Joseph, B (2); Marine, JC (2); Tavernarakis, N (2); Rubinsztein, DC (2); Stockwell, BR (2); Conrad, M (2); LIPTON, SA (2); CAMPANELLA, M (2); PanaretakiS, T (2); Blomgren, K (2); Ichijo, H (2); Gronemeyer, H (2); Ciechanover, A (2); Szabadkai, G (2); Lopez-Otin, C (2); Boya, P (2); Cecconi, F (2); Oren, M (2); Nunez, G (2); Rodrigues, CMP (2); Rudel, T (2); Aaronson, SA (2); Hetz, C (2); show less...

University: Karolinska Institutet (3)

Language: English (3)

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