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1.
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2.
  • Bree, N, et al. (author)
  • Shape Coexistence in the Neutron-Deficient Even-Even Hg182-188 Isotopes Studied via Coulomb Excitation.
  • 2014
  • In: Physical Review Letters. - 1079-7114. ; 112:16
  • Journal article (peer-reviewed)abstract
    • Coulomb-excitation experiments to study electromagnetic properties of radioactive even-even Hg isotopes were performed with 2.85 MeV/nucleon mercury beams from REX-ISOLDE. Magnitudes and relative signs of the reduced E2 matrix elements that couple the ground state and low-lying excited states in Hg182-188 were extracted. Information on the deformation of the ground and the first excited 0+ states was deduced using the quadrupole sum rules approach. Results show that the ground state is slightly deformed and of oblate nature, while a larger deformation for the excited 0+ state was noted in Hg182,184. The results are compared to beyond mean field and interacting-boson based models and interpreted within a two-state mixing model. Partial agreement with the model calculations was obtained. The presence of two different structures in the light even-mass mercury isotopes that coexist at low excitation energy is firmly established.
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3.
  • Wrzosek-Lipska, K., et al. (author)
  • Electromagnetic properties of low-lying states in neutron-deficient Hg isotopes : Coulomb excitation of 182Hg, 184Hg, 186Hg and 188Hg
  • 2019
  • In: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-6001 .- 1434-601X. ; 55:8
  • Journal article (peer-reviewed)abstract
    • The neutron-deficient mercury isotopes serve as a classical example of shape coexistence, whereby at low energy near-degenerate nuclear states characterized by different shapes appear. The electromagnetic structure of even-mass 182-188 Hg isotopes was studied using safe-energy Coulomb excitation of neutron-deficient mercury beams delivered by the REX-ISOLDE facility at CERN. The population of 01,2+, 21,2+ and 41+ states was observed in all nuclei under study. Reduced E2 matrix elements coupling populated yrast and non-yrast states were extracted, including their relative signs. These are a sensitive probe of shape coexistence and may be used to validate nuclear models. The experimental results are discussed in terms of mixing of two different configurations and are compared with three different model calculations: the Beyond Mean Field model, the Interacting Boson Model with configuration mixing and the General Bohr Hamiltonian. Partial agreement with experiment was observed, hinting to missing ingredients in the theoretical descriptions.
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4.
  • Ahrens, J., et al. (author)
  • Measurement of the cosmic ray composition at the knee with the SPASE-2/AMANDA-B10 detectors
  • 2004
  • In: Astroparticle physics. - : Elsevier. - 0927-6505 .- 1873-2852. ; 21:6, s. 565-581
  • Journal article (peer-reviewed)abstract
    • The mass composition of high-energy cosmic rays at energies above 1015 eV can provide crucial information for the understanding of their origin. Air showers were measured simultaneously with the SPASE-2 air shower array and the AMANDA-B10 Cherenkov telescope at the South Pole. This combination has the advantage to sample almost all high-energy shower muons and is thus a new approach to the determination of the cosmic ray composition. The change in the cosmic ray mass composition was measured versus existing data from direct measurements at low energies. Our data show an increase of the mean log atomic mass 〈lnA〉 by about 0.8 between 500 TeV and 5 PeV. This trend of an increasing mass through the "knee" region is robust against a variety of systematic effects. © 2004 Elsevier B.V. All rights reserved.
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5.
  • Ahrens, J., et al. (author)
  • Limits to the muon flux from WIMP annihilation in the center of the Earth with the AMANDA detector
  • 2002
  • In: Physical Review D. - : American Physical Society. - 1550-7998 .- 1550-2368. ; 66:3, s. 032006-
  • Journal article (peer-reviewed)abstract
    • A search for nearly vertical up-going muon-neutrinos from neutralino annihilations in the center of the Earth has been performed with the AMANDA-B10 neutrino detector. The data collected in 130.1 days of live time in 1997, ∼10 9 events, have been analyzed for this search. No excess over the expected atmospheric neutrino background has been observed. An upper limit at 90% confidence level has been obtained on the annihilation rate of neutralinos in the center of the Earth, as well as the corresponding muon flux limit, both as a function of the neutralino mass in the range 100 GeV-5000 GeV. © 2002 The American Physical Society.
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6.
  • Andres, E., et al. (author)
  • AMANDA : Status, results and future
  • 1999
  • In: Proceedings, 8th International Workshop, Venice, Italy, February 23-26, 1999. Vol. 1, 2. ; , s. 63-79
  • Conference paper (peer-reviewed)abstract
    • We review the status of the AMANDA neutrino telescope. We present resultsobtained from the four-string prototype array AMANDA-B4 and describe themethods of track reconstruction and neutrino event separation. We give also firstresults of the analysis of the 10-string detector AMANDA-B10, in particular onatmospheric neutrinos and the search for magnetic monopoles. We sketch thefuture schedule on the way to a cube kilometer telescope at the South Pole,ICECUBE.
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7.
  • Andrés, E. C., et al. (author)
  • The AMANDA neutrino telescope
  • 1999
  • In: Nuclear physics B, Proceedings supplements. - 0920-5632 .- 1873-3832. ; 77:1-3, s. 474-485
  • Journal article (peer-reviewed)abstract
    • With an effective telescope area of order 104 m2 for TeV neutrinos, a threshold near ∼50 GeV and a pointing accuracy of 2.5 degrees per muon track, the AMANDA detector represents the first of a new generation of high energy neutrino telescopes, reaching a scale envisaged over 25 years ago. We describe early results on the calibration of natural deep ice as a particle detector as well as on AMANDA's performance as a neutrino telescope.
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8.
  • Andrés, E., et al. (author)
  • Observation of high-energy neutrinos using Čerenkov detectors embedded deep in Antarctic ice
  • 2001
  • In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 410:6827, s. 441-443
  • Journal article (peer-reviewed)abstract
    • Neutrinos are elementary particles that carry no electric charge and have little mass. As they interact only weakly with other particles, they can penetrate enormous amounts of matter, and therefore have the potential to directly convey astrophysical information from the edge of the Universe and from deep inside the most cataclysmic high-energy regions. The neutrino's great penetrating power, however, also makes this particle difficult to detect. Underground detectors have observed low-energy neutrinos from the Sun and a nearby supernova2, as well as neutrinos generated in the Earth's atmosphere. But the very low fluxes of high-energy neutrinos from cosmic sources can be observed only by much larger, expandable detectors in, for example, deep water3,4 or ice5. Here we report the detection of upwardly propagating atmospheric neutrinos by the ice-based Antarctic muon and neutrino detector array (AMANDA). These results establish a technology with which to build a kilometre-scale neutrino observatory necessary for astrophysical observations1.
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9.
  • Andrés, E., et al. (author)
  • Recent results from AMANDA
  • 2001
  • In: International Journal of Modern Physics A. - 0217-751X .- 1793-656X. ; 16:1C, s. 1013-1015
  • Journal article (peer-reviewed)abstract
    • We present results based on data taken in 1997 with the 302-PMT Antarctic Muon and Neutrino Detector Array-B10 ("AMANDA-B10") array. Atmospheric neutrinos created in the northern hemisphere are observed indirectly through their charged current interactions which produce relativistic, Cherenkov-light-emitting upgoing muons in the South Pole ice cap. The reconstructed angular distribution of these events is in good agreement with expectation and demonstrates the viability of this ice-based device as a neutrino telescope.
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10.
  • Andres, E., et al. (author)
  • Results from the AMANDA high energy neutrino detector
  • 2000
  • In: Nuclear physics B, Proceedings supplements. - : Elsevier. - 0920-5632 .- 1873-3832. ; 91:1-3, s. 423-430
  • Journal article (peer-reviewed)abstract
    • This paper briefly summarizes the search for astronomical sources of high-energy neutrinos using the AMANDA-B10 detector. The complete data set from 1997 was analyzed. For Eμ > 10 TeV, the detector exceeds 10,000 m2 in effective area between declinations of 25 and 90 degrees. Neutrinos generated in the atmosphere by cosmic ray interactions were used to verify the overall sensitivity of the detector. The absolute pointing accuracy and angular resolution has been confirmed by the analysis of coincident events between the SPASE air shower array and the AMANDA detector. Preliminary flux limits from point source candidates are presented. For declinations larger than +45 degrees, our results compare favorably to existing limits for sources in the Southern sky. We also present the current status of the searches for high energy neutrino emission from diffusely distributed sources, GRBs, and WIMPs from the center of the earth.
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11.
  • Andrés, E., et al. (author)
  • Status of the AMANDA experiment
  • 1999
  • In: Nuclear physics B, Proceedings supplements. - : Elsevier. - 0920-5632 .- 1873-3832. ; 70:1-3, s. 448-452
  • Journal article (peer-reviewed)abstract
    • The AMANDA high energy neutrino telescope has successfully been increased in size from four detector strings to ten detector strings during the 1996/1997 season. The first upward going muon-neutrino candidates have been reconstructed from the 1996 year's four-string data. Three new detector strings will be deployed during 1997/1998 to 2350 metres depth.
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12.
  • Andres, E., et al. (author)
  • The AMANDA neutrino telescope : Principle of operation and first results
  • 2000
  • In: Astroparticle physics. - : Elsevier. - 0927-6505 .- 1873-2852. ; 13:1, s. 1-20
  • Journal article (peer-reviewed)abstract
    • AMANDA is a high-energy neutrino telescope presently under construction at the geographical South Pole. In the Antarctic summer 1995/96, an array of 80 optical modules (OMs) arranged on 4 strings (AMANDA-B4) was deployed at depths between 1.5 and 2 km. In this paper we describe the design and performance of the AMANDA-B4 prototype, based on data collected between February and November 1996. Monte Carlo simulations of the detector response to down-going atmospheric muon tracks show that the global behavior of the detector is understood. We describe the data analysis method and present first results on atmospheric muon reconstruction and separation of neutrino candidates. The AMANDA array was upgraded with 216 OMs on 6 new strings in 1996/97 (AMANDA-B10), and 122 additional OMs on 3 strings in 1997/98.
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13.
  • Bashkanov, M., et al. (author)
  • Double-Pionic Fusion of Nuclear Systems and the "ABC" Effect : Approaching a Puzzle by Exclusive and Kinematically Complete Measurements
  • 2009
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 102:5, s. 052301-
  • Journal article (peer-reviewed)abstract
    • The ABC effect-a puzzling low-mass enhancement in the pi pi invariant mass spectrum, first observed by Abashian, Booth, and Crowe-is well known from inclusive measurements of two-pion production in nuclear fusion reactions. Here we report on the first exclusive and kinematically complete measurements of the most basic double-pionic fusion reaction pn -> d pi(0)pi(0) at beam energies of 1.03 and 1.35 GeV. The measurements, which have been carried out at CELSIUS-WASA, reveal the ABC effect to be a (pi pi)(I=L=0) channel phenomenon associated with both a resonancelike energy dependence in the integral cross section and the formation of a Delta Delta system in the intermediate state. A corresponding simple s-channel resonance ansatz provides a surprisingly good description of the data.
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14.
  • Bashkanov, M., et al. (author)
  • Two-pion production in proton-proton collisions
  • 2004
  • In: Hadron Spectroscopy, Tenth International Conference on Hadron Spectrscopy, Aschaffenburg, Germany 31 August - 6 September 2003. - 0735401977 ; , s. 241-244
  • Conference paper (other academic/artistic)
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15.
  • Bay, R. C., et al. (author)
  • The AMANDA neutrino telescope and the indirect search for dark matter : AMANDA Colaboration
  • 1998
  • In: Physics reports. - : Elsevier. - 0370-1573 .- 1873-6270. ; 307:1-4, s. 243-252
  • Journal article (peer-reviewed)abstract
    • With an effective telescope area of order 104m2, a threshold of ~50GeV and a pointing accuracy of 2.5°, the AMANDA detector represents the first of a new generation of high energy neutrino telescopes, reaching a scale envisaged over 25 years ago. We describe its performance, focussing on the capability to detect halo dark matter particles via their annihilation into neutrinos.
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16.
  • Fergusson, J. R., et al. (author)
  • CD161(int)CD8+T cells : a novel population of highly functional, memory CD8+T cells enriched within the gut
  • 2016
  • In: Mucosal Immunology. - : Elsevier BV. - 1933-0219 .- 1935-3456. ; 9:2, s. 401-413
  • Journal article (peer-reviewed)abstract
    • The C-type lectin-like receptor CD161 is expressed by lymphocytes found in human gut and liver, as well as blood, especially natural killer (NK) cells, T helper 17 (Th17) cells, and a population of unconventional Tcells known as mucosalassociated invariant T (MAIT) cells. The association of high CD161 expression with innate T-cell populations including MAITcells is established. Here we show that CD161 is also expressed, at intermediate levels, on a prominent subset of polyclonal CD8+ T cells, including antiviral populations that display a memory phenotype. These memory CD161(int)CD8+ Tcells are enriched within the colon and express both CD103 and CD69, markers associated with tissue residence. Furthermore, this population was characterized by enhanced polyfunctionality, increased levels of cytotoxic mediators, and high expression of the transcription factors T-bet and eomesodermin (EOMES). Such populations were induced by novel vaccine strategies based on adenoviral vectors, currently in trial against hepatitis C virus. Thus, intermediate CD161 expression marks potent polyclonal, polyfunctional tissue-homing CD8+ T-cell populations in humans. As induction of such responses represents a major aim of T-cell prophylactic and therapeutic vaccines in viral disease and cancer, analysis of these populations could be of value in the future.
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17.
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18.
  • Twardek, W. M., et al. (author)
  • Field assessments of heart rate dynamics during spawning migration of wild and hatchery-reared Chinook salmon
  • 2021
  • In: Philosophical Transactions of the Royal Society B-Biological Sciences. - : The Royal Society. - 0962-8436 .- 1471-2970. ; 376:1830
  • Journal article (peer-reviewed)abstract
    • During spawning, adult Pacific salmonids (Oncorhynchus spp.) complete challenging upriver migrations during which energy and oxygen delivery must be partitioned into activities such as locomotion, maturation and spawning behaviours under the constraints of an individual's cardiac capacity. To advance our understanding of cardiac function in free-swimming fishes, we implanted migrating adult Chinook salmon (Oncorhynchus tshawytscha) collected near the mouth of the Sydenham River, Ontario, with heart rate (f(H)) biologgers that recorded f(H) every 3 min until these semelparous fish expired on spawning grounds several days later. Fundamental aspects of cardiac function were quantified, including resting, routine and maximum f(H), as well as scope for f(H) (maximum-resting f(H)). Predictors of f(H) were explored using generalized least-squares regression, including water temperature, discharge, fish size and fish origin (wild versus hatchery). Heart rate was positively correlated with water temperature, which aligned closely with daily and seasonal shifts. Wild fish had slower resting heart rates than hatchery fish, which led to significantly higher scope for f(H). Our findings suggest that wild salmon may have better cardiac capacity during migration than hatchery fish, potentially promoting migration success in wild fish. This article is part of the theme issue 'Measuring physiology in free-living animals (Part I)'.
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19.
  • Warr, N., et al. (author)
  • The Miniball spectrometer
  • 2013
  • In: European Physical Journal A. Hadrons and Nuclei. - : Springer Science and Business Media LLC. - 1434-6001. ; 49:3
  • Journal article (peer-reviewed)abstract
    • The Miniball germanium detector array has been operational at the REX (Radioactive ion beam EXperiment) post accelerator at the Isotope Separator On-Line facility ISOLDE at CERN since 2001. During the last decade, a series of successful Coulomb excitation and transfer reaction studies have been performed with this array, utilizing the unique and high-quality radioactive ion beams which are available at ISOLDE. In this article, an overview is given of the technical details of the full Miniball setup, including a description of the.-ray and particle detectors, beam monitoring devices and methods to deal with beam contamination. The specific timing properties of the REX-ISOLDE facility are highlighted to indicate the sensitivity that can be achieved with the full Miniball setup. The article is finalized with a summary of some physics highlights at REX-ISOLDE and the utilization of the Miniball germanium detectors at other facilities.
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20.
  • Wischnewski, R., et al. (author)
  • The AMANDA neutrino detector : Status report
  • 2000
  • In: Nuclear physics B, Proceedings supplements. - 0920-5632 .- 1873-3832. ; 85:1-3, s. 141-145
  • Journal article (peer-reviewed)abstract
    • The first stage of the AMANDA High Energy Neutrino Detector at the South Pole, the 302 PMT array AMANDA-B10, is taking data since 1997. We describe results on atmospheric neutrinos, limits on indirect WIMP detection, seasonal muon flux variation, relativistic monopole flux limits, a search for gravitational collapse neutrinos, and a depth scan of the optical ice properties. The next stage 19-string detector AMANDA-II with ∼650 PMTs will be completed in spring 2000.
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21.
  • Wischnewski, R., et al. (author)
  • The AMANDA neutrino detector
  • 1999
  • In: Nuclear physics B, Proceedings supplements. - : Elsevier. - 0920-5632 .- 1873-3832. ; 75:1-2, s. 412-414
  • Journal article (peer-reviewed)abstract
    • The first stage of the AMANDA High Energy Neutrino Detector at the South Pole, the 302 PMT array AMANDA-B with an expected effective area for TeV neutrinos of ∼ 104 m2, has been taking data since 1997. Progress with calibration, investigation of ice properties, as well as muon and neutrino data analysis are described. The next stage 20-string detector AMANDA-II with ∼800 PMTs will be completed in spring 2000.
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22.
  • Ahrens, J., et al. (author)
  • Calibration and survey of AMANDA with the SPASE detectors
  • 2004
  • In: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier. - 0168-9002 .- 1872-9576. ; 522:3, s. 347-359
  • Journal article (peer-reviewed)abstract
    • We report on the analysis of air showers observed in coincidence by the Antarctic Muon and Neutrino detector array (AMANDA-B10) and the South Pole Air Shower Experiment (SPASE-1 and SPASE-2). We discuss the use of coincident events for calibration and survey of the deep AMANDA detector as well as the response of AMANDA to muon bundles. This analysis uses data taken during 1997 when both SPASE-1 and SPASE-2 were in operation to provide a stereo view of AMANDA. © 2003 Elsevier B.V. All rights reserved.
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23.
  • Ahrens, J., et al. (author)
  • Limits on diffuse fluxes of high energy extraterrestrial neutrinos with the AMANDA-B10 detector
  • 2003
  • In: Physical Review Letters. - : American Physical Society. - 0031-9007 .- 1079-7114. ; 90:25, s. 2511011-2511015
  • Journal article (peer-reviewed)abstract
    • A report on the limits, which could be placed on diffuse fluxes of high energy extraterrestrial neutrinos, was presented. The incorporation of neutrino oscillations was necessary for interpreting the limits in terms of the flux from a cosmological distributions of sources. The energetic accelerated environments were presented as the sources of high energy extraterrestrial neutrinos.
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24.
  • Ahrens, J., et al. (author)
  • Muon track reconstruction and data selection techniques in AMANDA
  • 2004
  • In: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier. - 0168-9002 .- 1872-9576. ; 524:1-3, s. 169-194
  • Journal article (peer-reviewed)abstract
    • The Antarctic Muon And Neutrino Detector Array (AMANDA) is a high-energy neutrino telescope operating at the geographic South Pole. It is a lattice of photo-multiplier tubes buried deep in the polar ice between 1500 and 2000 m. The primary goal of this detector is to discover astrophysical sources of high-energy neutrinos. A high-energy muon neutrino coming through the earth from the Northern Hemisphere can be identified by the secondary muon moving upward through the detector. The muon tracks are reconstructed with a maximum likelihood method. It models the arrival times and amplitudes of Cherenkov photons registered by the photo-multipliers. This paper describes the different methods of reconstruction, which have been successfully implemented within AMANDA. Strategies for optimizing the reconstruction performance and rejecting background are presented. For a typical analysis procedure the direction of tracks are reconstructed with about 2° accuracy. © 2004 Elsevier B.V. All rights reserved.
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25.
  • Ahrens, J., et al. (author)
  • Observation of high energy atmospheric neutrinos with the Antarctic muon and neutrino detector array
  • 2002
  • In: Physical Review D. - : American Physical Society. - 1550-7998 .- 1550-2368. ; 66:1, s. 120051-1200520
  • Journal article (peer-reviewed)abstract
    • The Antarctic muon and neutrino detector array (AMANDA) began collecting data with ten strings in 1997. Results from the first year of operation are presented. Neutrinos coming through the Earth from the Northern Hemisphere are identified by secondary muons moving upward through the array. Cosmic rays in the atmosphere generate a background of downward moving muons, which are about 106 times more abundant than the upward moving muons. Over 130 days of exposure, we observed a total of about 300 neutrino events. In the same period, a background of 1.05 × 109 cosmic ray muon events was recorded. The observed neutrino flux is consistent with atmospheric neutrino predictions. Monte Carlo simulations indicate that 90% of these events lie in the energy range 66 GeV to 3.4 TeV. The observation of atmospheric neutrinos consistent with expectations establishes AMANDA-B10 as a working neutrino telescope.
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26.
  • Ahrens, J., et al. (author)
  • Results from the AMANDA telescope
  • 2003
  • In: Nuclear Physics A. - : Elsevier. - 0375-9474 .- 1873-1554. ; 721, s. C545-C548
  • Journal article (peer-reviewed)abstract
    • We present results from the AMANDA high energy neutrino telescope located at the South Pole. They include measurements of the atmospheric neutrino flux, search for UHE point sources, and diffuse sources producing electromagnetic/hadronic showers at the detector or close to it.
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27.
  • Ahrens, J., et al. (author)
  • Results from the Antarctic muon and nuetrino detector array
  • 2003
  • In: Nuclear physics B, Proceedings supplements. - : Elsevier. - 0920-5632 .- 1873-3832. ; 118, s. 371-379
  • Journal article (peer-reviewed)abstract
    • We show new results from both the older and newer incarnations of AMANDA (AMANDA-B10 and AMANDA-II, respectively). These results demonstrate that AMANDA is a functioning, multipurpose detector with significant physics and astrophysics reach. They include a new higher-statistics measurement of the atmospheric muon neutrino flux and preliminary results from searches for a variety of sources of ultrahigh energy neutrinos: generic point sources, gamma-ray bursters and diffuse sources producing muons in the detector, and diffuse sources producing electromagnetic or hadronic showers in or near the detector.
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28.
  • Ahrens, J., et al. (author)
  • Search for Extraterrestrial Point Sources of Neutrinos with AMANDA-II
  • 2004
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 92:7, s. 711021-711025
  • Journal article (peer-reviewed)abstract
    • The results of a search for point sources of high energy neutrinos in the northern hemisphere were presented using AMANDA-II data collected in the year 2000. The results included the flux limits on several active-galactic-nuclei blazars, microquasars, magnetars, and other candidate neutrino sources. A search for excesses above a random background of cosmic ray induced atmospheric neutrinos and misreconstructed downgoing cosmic-rays muons, which revealed no statistically significant neutrino point sources was also presented. It was shown that AMANDA-II had achieved the sensitivity required to probe known TeV γ-ray sources such as the blazar Markarian 501 in its 1997 flaring state at a level where neutrino and γ-ray fluxes were equal.
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29.
  • Astell, A. J., et al. (author)
  • Developing a pragmatic evaluation of ICTs for older adults with cognitive impairment at scale : the IN LIFE experience
  • 2022
  • In: Universal Access in the Information Society. - Heidelberg, Germany : Springer. - 1615-5289 .- 1615-5297. ; 21:1, s. 1-19
  • Journal article (peer-reviewed)abstract
    • Implementing information and communications technology (ICT) at scale requires evaluation processes to capture the impacton users as well as the infrastructure into which it is being introduced. For older adults living with cognitive impairment, thisrequires evaluation that can accommodate diferent levels of cognitive impairment, alongside input from family and formalcaregivers, plus stakeholder organisations. The European Horizon 2020 project INdependent LIving support Functions forthe Elderly (IN LIFE) set out to integrate 17 technologies into a single digital platform for older people living with cognitive impairment plus their families, care providers and stakeholders. The IN LIFE evaluation took place across six nationalpilot sites to examine a number of variables including impact on the users, user acceptance of the individual services andthe overall platform, plus the economic case for the IN LIFE platform. The results confrmed the interest and need amongolder adults, family caregivers, formal caregivers and stakeholders, for information and communications technology (ICT).Relative to the baseline, quality of life improved and cognition stabilised; however, there was an overall reluctance to payfor the platform. The fndings provide insights into existing barriers and challenges for adoption of ICT for older peopleliving with cognitive impairment.
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30.
  • Astell, A. J., et al. (author)
  • Developing a pragmatic evaluation of ICTs for older adults with cognitive impairment at scale: the IN LIFE experience
  • 2021
  • In: Universal Access in the Information Society. - Heidelberg, Germany : Springer. - 1615-5289 .- 1615-5297.
  • Journal article (peer-reviewed)abstract
    • Implementing information and communications technology (ICT) at scale requires evaluation processes to capture the impact on users as well as the infrastructure into which it is being introduced. For older adults living with cognitive impairment, this requires evaluation that can accommodate different levels of cognitive impairment, alongside input from family and formal caregivers, plus stakeholder organisations. The European Horizon 2020 project INdependent LIving support Functions for the Elderly (IN LIFE) set out to integrate 17 technologies into a single digital platform for older people living with cognitive impairment plus their families, care providers and stakeholders. The IN LIFE evaluation took place across six national pilot sites to examine a number of variables including impact on the users, user acceptance of the individual services and the overall platform, plus the economic case for the IN LIFE platform. The results confirmed the interest and need among older adults, family caregivers, formal caregivers and stakeholders, for information and communications technology (ICT). Relative to the baseline, quality of life improved and cognition stabilised; however, there was an overall reluctance to pay for the platform. The findings provide insights into existing barriers and challenges for adoption of ICT for older people living with cognitive impairment.
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31.
  • Bargholtz, Chr., et al. (author)
  • Measurement of the eta -> pi(+)pi(-)e(+)e(-) decay branching ratio
  • 2007
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 644:5-6, s. 299-303
  • Journal article (peer-reviewed)abstract
    • The reaction pd -> He-3 eta at threshold was used to provide a clean source of eta mesons for decay studies with the WASA detector at CELSIUS. The branching ratio of the decay eta -> pi(+)pi(-)e(+)e(-) is measured to be (4.3 +/- 1.3 +/- 0.4) x 10(-4).
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32.
  • Bargholtz, Chr., et al. (author)
  • The WASA detector facility at CELSIUS
  • 2008
  • In: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 594:3, s. 339-350
  • Journal article (peer-reviewed)abstract
    • The WASA 4 pi multidetector system, aimed at investigating light meson production in light ion collisions and eta meson rare decays at the CELSIUS storage ring in Uppsala is presented. A unique feature of the system is the use of hydrogen pellets as internal targets for the first time. A detailed description of the design, together with the anticipated and achieved performance parameters are given. (C) 2008 Elsevier B.V. All rights reserved.
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33.
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34.
  • DiJulio, Douglas, et al. (author)
  • Electromagnetic properties of vibrational bands in Er-170
  • 2011
  • In: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-6001 .- 1434-601X. ; 47:2, s. 25-
  • Journal article (peer-reviewed)abstract
    • Excited states of the nucleus Er-170 have been studied by Coulomb excitation using the GASP gamma-ray detector system at the Laboratori Nazionali di Legnaro. The ground-state band along with a low-lying K-pi = 0(+) band and gamma-vibrational band were populated during the experiment. Based on the measured gamma-ray yields, a set of interband and intraband matrix elements has been extracted using the Coulomb excitation code GOSIA. The resulting E2 matrix elements are compared to collective model predictions.
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35.
  • Ekström, Andreas, 1979, et al. (author)
  • Impairment of branchial and coronary blood flow reduces reproductive fitness, but not cardiac performance in paternal smallmouth bass (Micropterus dolomieu).
  • 2022
  • In: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. - : Elsevier BV. - 1531-4332 .- 1095-6433. ; 267:May 2022
  • Journal article (peer-reviewed)abstract
    • The capacity to extract oxygen from the water, and the ability of the heart to drive tissue oxygen transport, are fundamental determinants of important life-history performance traits in fish. Cardiac performance is in turn dependent on the heart's own oxygen supply, which in some teleost species is partly delivered via a coronary circulation originating directly from the gills that perfuses the heart, and is crucial for cardiac, metabolic and locomotory capacities. It is currently unknown, however, how a compromised branchial blood flow (e.g., by angling-induced hook damage to the gills), constraining oxygen uptake and coronary blood flow, affects the energetically demanding parental care behaviours and reproductive fitness in fish. Here, we tested the hypothesis that blocking ¼ of the branchial blood flow and abolishing coronary blood flow would negatively affect parental care behaviours, cardiac performance (heart rate metrics, via implanted Star-Oddi heart rate loggers) and reproductive fitness of paternal smallmouth bass (Micropterus dolomieu). Our findings reveal that branchial/coronary ligation compromised reproductive fitness, as reflected by a lower proportion of broods reaching free-swimming fry and a tendency for a higher nest abandonment rate relative to sham operated control fish. While this was associated with a tendency for a reduced aggression in ligated fish, parental care behaviours were largely unaffected by the ligation. Moreover, the ligation did not impair any of the heart rate performance metrics. Our findings highlight that gill damage may compromise reproductive output of smallmouth bass populations during the spawning season. Yet, the mechanism(s) behind this finding remains elusive.
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36.
  • Ekström, Linda M N K, et al. (author)
  • Oat β-glucan containing bread increases the glycaemic profile
  • 2017
  • In: Journal of Functional Foods. - : Elsevier BV. - 1756-4646. ; 32, s. 106-111
  • Journal article (peer-reviewed)abstract
    • A net postprandial glucose increment beyond 2 h has been shown to improve glucose and appetite regulation at a subsequent meal. Such an improved glycaemic profile (GP) has been reported for bread containing guar gum. In the present study three commercially available β-glucans from barley and oat were baked into yeast leavened bread products. Only oat beta-glucan containing bread met the criteria of β-glucan molecular weight and was included in a meal study. The three levels of oat β-glucans reduced the GI and glucose iPeak by 32–37% compared to a white wheat reference bread. Furthermore, the highest oat β-glucan level increased GP by 66% compared to the reference bread. It is concluded that the oat β-glucans were suitable for use in baking, since the MW remained relatively high. Thus, the oat ingredient showed an interesting potential to be used when tailoring the glycaemic profile of bread products.
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37.
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38.
  • Fergusson, Joannah R., et al. (author)
  • CD161 Defines a Transcriptional and Functional Phenotype across Distinct Human T Cell Lineages
  • 2014
  • In: Cell Reports. - : Elsevier BV. - 2211-1247. ; 9:3, s. 1075-1088
  • Journal article (peer-reviewed)abstract
    • The C-type lectin CD161 is expressed by a large proportion of human T lymphocytes of all lineages, including a population known as mucosal-associated invariant T (MAIT) cells. To understand whether different T cell subsets expressing CD161 have similar properties, we examined these populations in parallel using mass cytometry and mRNA microarray approaches. The analysis identified a conserved CD161++/MAIT cell transcriptional signature enriched in CD161+CD8+ T cells, which can be extended to CD161+ CD4+ and CD161+TCR gamma delta+ T cells. Furthermore, this led to the identification of a shared innate-like, TCR-independent response to interleukin (IL)-12 plus IL-18 by different CD161-expressing T cell populations. This response was independent of regulation by CD161, which acted as a costimulatory molecule in the context of T cell receptor stimulation. Expression of CD161 hence identifies a transcriptional and functional phenotype, shared across human T lymphocytes and independent of both T cell receptor (TCR) expression and cell lineage.
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39.
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40.
  • Hurst, A. M., et al. (author)
  • Measurement of the sign of the spectroscopic quadrupole moment for the 2(1)(+) state in Se-70: No evidence for oblate shape
  • 2007
  • In: Physical Review Letters. - 1079-7114. ; 98:7
  • Journal article (peer-reviewed)abstract
    • Using a method whereby molecular and atomic ions are independently selected, an isobarically pure beam of Se-70 ions was postaccelerated to an energy of 206 MeV using REX-ISOLDE. Coulomb-excitation yields for states in the beam and target nuclei were deduced by recording deexcitation gamma rays in the highly segmented MINIBALL gamma-ray spectrometer in coincidence with scattered particles in a silicon detector. At these energies, the Coulomb-excitation yield for the first 2(+) state is expected to be strongly sensitive to the sign of the spectroscopic quadrupole moment through the nuclear reorientation effect. Experimental evidence is presented here for a prolate shape for the first 2(+) state in Se-70, reopening the question over whether there are, as reported earlier, deformed oblate shapes near to the ground state in the light selenium isotopes.
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41.
  • Johansen, I. B., et al. (author)
  • Bigger is not better: cortisol-induced cardiac growth and dysfunction in salmonids
  • 2017
  • In: Journal of Experimental Biology. - : The Company of Biologists. - 0022-0949 .- 1477-9145. ; 220:14, s. 2545-2553
  • Journal article (peer-reviewed)abstract
    • Stress and elevated cortisol levels are associated with pathological heart growth and cardiovascular disease in humans and other mammals. We recently established a link between heritable variation in post-stress cortisol production and cardiac growth in salmonid fish too. A conserved stimulatory effect of the otherwise catabolic steroid hormone cortisol is probably implied, but has to date not been established experimentally. Furthermore, whereas cardiac growth is associated with failure of the mammalian heart, pathological cardiac hypertrophy has not previously been described in fish. Here, we show that rainbow trout (Oncorhynchus mykiss) treated with cortisol in the diet for 45 days have enlarged hearts with lower maximum stroke volume and cardiac output. In accordance with impaired cardiac performance, overall circulatory oxygen-transporting capacity was diminished as indicated by reduced aerobic swimming performance. In contrast to the well-known adaptive/physiological heart growth observed in fish, cortisol-induced growth is maladaptive. Furthermore, the observed heart growth was associated with up-regulated signature genes of mammalian cardiac pathology, suggesting that signalling pathways mediating cortisol-induced cardiac remodelling in fish are conserved from fish to mammals. Altogether, we show that excessive cortisol can induce pathological cardiac remodelling. This is the first study to report and integrate the etiology, physiology and molecular biology of cortisol-induced pathological remodelling in fish.
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42.
  • Kren, F., et al. (author)
  • THE pp -> d pi(+)pi(0) REACTION - A CASE OF Delta Delta EXCITATION WITHOUT ABC-EFFECT
  • 2009
  • In: International Journal of Modern Physics A. - 0217-751X .- 1793-656X. ; 24:2-3, s. 561-563
  • Journal article (peer-reviewed)abstract
    • The ABC effect, a low-mass enhancement in the invariant pp mass, is observed in double-pionic fusion reactions leading to a bound nuclear system in the final state. From previous measurements there have been indications that this phenomenon is resctricted to the sigma channel of the pp system. With exclusive measurements of the pp -> d pi(+)pi(0) reaction at T-p = 1.1 GeV we demonstrate that, indeed, the ABC effect does not occur in the vector-isovector Delta Delta channel (rho channel) despite the fact that the Delta Delta excitation is oberved to be the dominant reaction process. We also show that this reaction is well described by a t-channel Delta Delta excitation with the subsequent decay into the vector-isovector Delta Delta channel given by the rho channel operator.
  •  
43.
  • Kröll, Th, et al. (author)
  • Quadrupole Collectivity of neutron-rich nuclei around 132Sn
  • 2008
  • In: Frontiers in Nuclear Structure, Astrophysics, and Reactions, FINUSTAR 2007. - : AIP. - 9780735405325 ; 1012, s. 296-299
  • Conference paper (peer-reviewed)abstract
    • We report on the "safe" Coulomb excitation of neutron-rich Cd, Xe, and Ba isotopes in the vicinity of the doubly-magic nucleus 132Sn. The radioactive nuclei have been produced by ISOLDE at CERN and postaccelerated by the REX-ISOLDE facility. The γ-decay of excited states has been detected by the MINIBALL array. The presented preliminary results for the B(E2) values are consistent with expectations from phenomenological systematics and will be compared with theoretical calculations.
  •  
44.
  • Schönning, Karin, et al. (author)
  • Polarisation of the omega meson in the pd -> He-3 omega reaction at 1360 and 1450 MeV
  • 2008
  • In: Physics Letters B. - elsevier : Elsevier BV. - 0370-2693 .- 1873-2445. ; 668:4, s. 258-262
  • Journal article (peer-reviewed)abstract
    • The tensor polarisation of omega mesons produced in the pd -> He-3 omega reaction has been studied at two energies near threshold. The 3 He nuclei were detected in coincidence with the pi(0)pi(+)pi(-) or pi(0)gamma decay products of the omega. in contrast to the case of phi-meson production, the omega mesons are found to be unpolarised. This brings into question the applicability of the Okubo-Zweig-lizuka rule when comparing the production of vector mesons in low energy hadronic reactions.
  •  
45.
  • Schönning, Karin, et al. (author)
  • Production of the omega meson in the pd -> He-3 omega reaction at 1450 MeV and 1360 MeV
  • 2009
  • In: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 79:4, s. 044002-
  • Journal article (peer-reviewed)abstract
    • The production of omega mesons in the pd -> He-3 omega reaction has been studied at two energies near the kinematic threshold, T-p = 1450 MeV and T-p = 1360 MeV. The differential cross section was measured as a function of the omega c.m. angle at both energies over the whole angular range. Whereas the results at 1360 MeV are consistent with isotropy, strong rises are observed near both the forward and backward directions at 1450 MeV. Calculations made using a two-step model with an intermediate pion fail to reproduce the shapes of the measured angular distributions and also underestimate the total cross sections.
  •  
46.
  • Schönning, Karin, et al. (author)
  • The pd →3Heηπ0 reaction at Tp = 1450 MeV
  • 2010
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 685:1, s. 33-37
  • Journal article (peer-reviewed)abstract
    • The cross section for the pd→3Heηπ0 reaction has been measured at a beam energy of 1450 MeV using the WASA detector at the CELSIUS storage ring and detecting one 3He and four photons from the decays of the two mesons. The data indicate that the production mechanism involves the formation of the Δ(1232) isobar. Although the beam energy does not allow the full peak of this resonance to be seen, the invariant masses of all three pairs of final particles are well reproduce dby a phase space Monte Carlo simulation weighted with the p-wave factor of the square of the π0 momentum in the 3He π0 system.
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47.
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48.
  • Seidlitz, M., et al. (author)
  • Coulomb excitation of Mg-31
  • 2011
  • In: Physics Letters. Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 700:3-4, s. 181-186
  • Journal article (peer-reviewed)abstract
    • The ground state properties of Mg-31 indicate a change of nuclear shape at N = 19 with a deformed J(pi) = 1/2(+) intruder state as a ground state, implying that Mg-31 is part of the "island of inversion". The collective properties of excited states were the subject of a Coulomb excitation experiment at REX-ISOLDE, CERN, employing a radioactive Mg-31 beam. De-excitation gamma-rays were detected by the MINIBALL gamma-spectrometer in coincidence with scattered particles in a segmented Si-detector. The level scheme of Mg-3I was extended. Spin and parity assignment of the 945 keV state yielded 5/2(+) and its de-excitation is dominated by a strong collective M1 transition. Comparison of the transition probabilities of Mg-30,Mg-31,Mg-32 establishes that for the N = 19 magnesium isotope not only the ground state but also excited states are largely dominated by a deformed pf intruder configuration. (C) 2011 Elsevier B.V. All rights reserved.
  •  
49.
  • Skorodko, T., et al. (author)
  • Delta Delta excitation in proton-proton induced pi(0)pi(0) production
  • 2011
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 695:1-4, s. 115-123
  • Journal article (peer-reviewed)abstract
    • Exclusive measurements of the pp -> pp pi(0)pi(0) reaction have been performed at CELSIUS/WASA at energies from threshold up to T-p = 1.3 GeV. Total and differential cross sections have been obtained. Here we concentrate on energies T-p >= GeV. where the Delta Delta excitation becomes the leading process. No evidence is found for a significant ABC effect beyond that given by the conventional t-channel Delta Delta excitation. This holds also for the double-pionic fusion to the quasibound He-2. The data are compared to model predictions, which are based on both pi- and rho-exchange. Total and differential cross sections are at variance with these predictions and call for a profound modification of the rho-exchange. A phenomenological modification allowing only a small rho-exchange contribution leads to a quantitative description of the data.
  •  
50.
  • Skorodko, T., et al. (author)
  • Excitation of the Roper resonance in single- and double-pion production in nucleon-nucleon collisions
  • 2008
  • In: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-6001 .- 1434-601X. ; 35:3, s. 317-319
  • Journal article (peer-reviewed)abstract
    • In most investigations the Roper resonance is sensed only very indirectly via complex partial-wave analyses. We find indications for its excitation in the invariant n pi(+) mass spectrum of the pp -> np pi(+) reaction at M approximate to 1360 MeV with a width of approximate to 150 MeV . The values fit very favorably to the most recent phase shift results as well as to the observations at BES. In the near-threshold two-pion production pp -> pp pi(0)pi(0) , where the Roper excitation and its subsequent decays via the routes N* -> Delta pi -> N pi pi and N* -> N sigma are the only dominant processes, we find its direct decay into the N sigma channel to be the by far dominating decay process -in favor of a monopole excitation of the Roper resonance.
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