| 1. |
- Kristiansen, Ingela, 1961-, et al.
(author)
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Omhändertagande vid förvärvad hjärnskada
- 2017. - 1
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In: Barnneurologi. - Lund : Studentlitteratur AB. - 9789144078885 ; , s. 517-524
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Book chapter (other academic/artistic)
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| 2. |
- Aaro Jonsson, Catherine C., et al.
(author)
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Variability in quality of life 13 years after traumatic brain injury in childhood
- 2014
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In: International Journal of Rehabilitation Research. - : Wolters Kluwer. - 0342-5282 .- 1473-5660. ; 37:4, s. 317-322
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Journal article (peer-reviewed)abstract
- With the aim of describing variability in the long-term outcome of quality of life after neurosurgically treated pediatric traumatic brain injury, mostly self-reports of 21 individuals with mild or moderate/severe injury were gathered using Mayo-Portland Adaptability Inventory in telephone interviews 13 years aftyer injury. A majority of the participants reported brain injury-related problems. The median outcome on Mayo-Portland Adaptability Inventory was mild to moderate limitations. The variation within the moderate/severe group varied between relatively good outcome and moderate/severe limitations. Concentration, irritability, fatigue, and transportation were reported as the most problematic areas, whereas self-care was reported as well functioning. Societal participation appeared to be the best functional domain in this Swedish study. Examples of individual reports of the life-situation at various outcome levels were provided. Variability in outcome is large within severity groups, and research may gain by addressing both outcomes of the individuals and groups. Objective questions of outcome should be accompanied by questions of actual functioning in everyday life. To ensure long-term support for quality of life for those with remaining dysfunction after pediatric traumatic brain injury, healthcare systems should implement systematic routines for referral to rehabilitation and support.
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| 3. |
- Aaro Jonsson, Catherine, 1963-, et al.
(author)
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Long-term cognitive outcome after neurosurgically treated childhood traumatic brain injury
- 2009
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In: Brain Injury. - : Taylor & Francis. - 0269-9052 .- 1362-301X. ; 23:13-14, s. 1008-1016
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Journal article (peer-reviewed)abstract
- Objective: To explore the cognitive long term outcome of two cohorts of patients neurosurgically treated for childhood traumatic brain injury (CTBI), either in 1987-1991 according to an older concept, or 1997-2001 with a stronger emphasis on volume targeted interventions. Research design and methods: Participants in the two cohorts were subject to an extensive neuropsychological assessment, 13.2 and 6.1 years post injury, respectively. In a between group design, assessment results of the two cohorts, n 18 and n 23, were compared to each other and to controls. Data were analyzed with multivariate analyses of variance. Results: Long-term cognitive deficits for both groups of similar magnitude and character were observed in both groups. Abilities were especially low regarding executive and memory function and verbal IQ. The cognitive results are discussed in terms of vulnerability of verbal functions and decreased executive control over memory-functions. Conclusions: There is a definite need for long term follow up of cognitive deficits after neurosurgically treated CTBI, also with the newer neurosurgical concept. Verbal learning and the executive control over memory functions should be addressed with interventions aimed at restoration, coping and compensation.
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| 4. |
- Aaro Jonsson, Catherine
(author)
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Long-term cognitive outcome of childhood traumatic brain injury
- 2010
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Doctoral thesis (other academic/artistic)abstract
- There is limited knowledge of cognitive outcome extending beyond 5 years after childhood traumatic brain injury, CTBI. The main objectives of this thesis were to investigate cognitive outcome at 6-14 years after CTBI, and to evaluate if advancements in the neurosurgical care, starting 1992, did influence long-term outcome and early epidemiology. An additional aim was to study the relationship between early brain injury parameters and early functional outcome. Study 1 evaluated cognitive progress during 14 years after CTBI, over three neuropsychological assessments in 8 patients with serious CTBI. Study 2 used patient records to investigate early epidemiology, received rehabilitation and medical follow up in two clinical cohorts, n=82 and n=46, treated neurosurgically for CTBI before and after 1992. An exploratory cluster analysis was applied to analyse the relation between early brain injury severity parameters and early functional outcome. In Study 3, participants in the two cohorts, n=18 and n=23, treated neurosurgically for CTBI before and after 1992, were subject to an extensive neuropsychological assessment, 13 and 6 years after injury, respectively. Assessment results of the two cohorts were compared with each other and with controls. Data were analysed with multivariate analyses of variance. Results and discussion. There were significant long-term cognitive deficits of similar magnitude and character in the two cohorts with CTBI, treated before and after the advancements in neurosurgical care. At 6-14 years after injury, long-term deficits in verbal intellectual and executive functions were found, and were discussed in terms of their late maturation and a decreased executive control over verbal memory-functions after CTBI. Visuospatial functions had a slightly better long-term recovery. The amount of rehabilitation received was equally low in both cohorts. The length of time spent in intensive care and the duration of care in the respirator may have a stronger relationship to early outcome than does a single measure of level of consciousness at admission. Main conclusions are that cognitive deficits are apparent at long-term follow up, 6-13 years after neurosurgically treated CTBI, even after advancements in the neurosurgical care in Sweden. Measures of verbal IQ, verbal memory and executive functions were especially low while visuospatial intellectual functions appear to have a better long-term recovery.
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| 5. |
- Aaro Jonsson, Catherine, 1963-, et al.
(author)
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Neuropsychological progress during 14 years after severe traumatic brain injury in childhood and adolescence
- 2004
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In: Brain Inj. - : Informa UK Limited. - 0269-9052 .- 1362-301X. ; 18:9, s. 921-34
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Journal article (peer-reviewed)abstract
- OBJECTIVE: To investigate the impact of time since injury on neuropsychological and psychosocial outcome after serious TBI in childhood or adolescence. METHODS: The subjects were eight patients with serious TBI sustained at a mean age of 14 years who had been assessed neuropsychologically at 1, 7 and 14 years after TBI. A retrospective longitudinal design was chosen to describe the development in six neuropsychological domains on the basis of the assessments. Psychosocial data were gathered from clinical knowledge and a semi-structured interview 14 years after TBI. RESULTS: Performance of verbal IQ shows a declining trend over the three assessments, that the performance of attention and working memory is low and that verbal learning is the cognitive domain which exhibits the largest impairments. The main psychosocial result is that three of the eight subjects went from a school situation with no adjustments to adult life with early retirement. CONCLUSIONS: Time since insult is an important factor when assessing outcome after TBI in childhood and adolescence and that assessment of final outcome should not be done before adulthood.
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| 6. |
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| 7. |
- Dahl, E., et al.
(author)
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A prospective, population-based, follow-up study of mild traumatic brain injury in children
- 2006
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In: Injury. - : Elsevier BV. - 0020-1383. ; 37:5, s. 402-9
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Journal article (peer-reviewed)abstract
- OBJECTIVE: Outline the annual incidence of mild traumatic brain injury in children, aged 0-17 years, using the American Congress of Rehabilitation Medicine classification and record the presence of new symptoms up to six months after injury. SETTINGS AND METHODS: The study population comprised all the children in the age group of 0-17 years (a total of 40,984) in an administrative district in south-western Sweden. All the individuals registered in the Brain Injury Register, during the periods 1 January to 30 June 1999 and 1 April to 30 September 2000, fulfilling the inclusion criteria defined by American Congress of Rehabilitation Medicine, were included. New symptoms occurring three to six months after the injury were recorded using a mailed 21-item questionnaire. RESULTS: 192 children fulfilled the criteria, yielding an annual incidence of 468/100,000 (95% CI 402-535/100,000). Boys accounted for 57 per cent and fall injuries accounted for 61 per cent of the external causes. New symptoms were reported by 24 per cent of those who answered the questionnaire. CONCLUSION: This study revealed that the annual incidence of mild traumatic brain injury in children was almost as high as that among adults in the same area and population.
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| 8. |
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| 9. |
- Elgmark Andersson, Elisabeth, et al.
(author)
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Mild traumatic brain injuries: the impact of early intervention on late sequelae. A randomized controlled trial
- 2007
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In: Acta Neurochir (Wien). - : Springer Science and Business Media LLC. - 0001-6268 .- 0942-0940. ; 149:2
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Journal article (peer-reviewed)abstract
- BACKGROUND: Positive results from early clinical intervention of mild traumatic brain injury (MTBI) patients by rehabilitation specialists have been reported. Various treatments have been used, but few controlled studies are published. We hypothesised that early rehabilitation of selected MTBI patients would reduce long term sequelae. METHOD: A randomised controlled trial with one year follow-up. Among 1719 consecutive patients with MTBI, 395 individuals, 16-60 years of age, met the MTBI definition. Exclusion criteria were: previous clinically significant brain disorders and/or a history of substance abuse. The control group (n = 131) received regular care. The intervention group (n = 264) was examined by a rehabilitation specialist. 78 patients were mainly referred to an occupational therapist. The problems were identified in daily activities and in terms of post-concussion symptoms (PCS), an individualised, tailored treatment was given. Primary endpoint was change in rate of PCS and in life satisfaction at one-year follow-up between the groups. FINDINGS: No statistical differences were found between the intervention and control groups. Patients who experienced few PCS two to eight weeks after the injury and declined rehabilitation recovered and returned to their pre-injury status. Patients who suffered several PCS and accepted rehabilitation did not recover after one year. INTERPRETATION: In this particular MTBI sample, early active rehabilitation did not change the outcome to a statistically-significant degree. Further studies should focus on patients with several complaints during the first 1-3 months and test various types of interventions.
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| 10. |
- Elgmark Andersson, Elisabeth, et al.
(author)
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The new Swedish Post-Concussion Symptoms questionnaire: a measure of symptoms after mild traumatic brain injury and its concurrent validity and inter-rater reliability.
- 2006
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In: Journal of rehabilitation medicine : official journal of the UEMS European Board of Physical and Rehabilitation Medicine. - : Medical Journals Sweden AB. - 1650-1977 .- 1651-2081. ; 38:1, s. 26-31
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Journal article (peer-reviewed)abstract
- OBJECTIVE: To study the concurrent validity and the inter-rater reliability of the Post-Concussion Symptoms Questionnaire. DESIGN: The approach was to study the concurrent validity of the Post-Concussion Symptoms Questionnaire when used as an interview questionnaire compared with a self-report questionnaire administered by the patients. The inter-rater reliability was also studied when 2 different raters administered the Post-Concussion Symptoms Questionnaire interview. PATIENTS: Thirty-five patients with mild traumatic brain injury were consecutively contacted by telephone and asked whether they would be willing to participate in a follow-up intervention. METHODS: The Post-Concussion Symptoms Questionnaire was completed by the patients, who answered "Yes" or "No" to the standardized questions. The patients were then interviewed to check the certain "Yes" or "No" answers, 0-10 days after having completed the first Post-Concussion Symptoms Questionnaire. The raters filled in their ratings independently. RESULTS: The concurrent validity of answers in the questionnaire compared with those in the interview ranged from 82% to 100% agreement. The inter-rater reliability results ranged from 93% to 100% agreement between the raters. CONCLUSION: The Post-Concussion Symptoms Questionnaire with answers of "Yes" or "No" is a valid instrument. High reliability was found between the raters.
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| 11. |
- Emanuelson, Ingrid, 1955, et al.
(author)
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Computed tomography and single-photon emission computed tomography as diagnostic tools in acquired brain injury among children and adolescents.
- 1997
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In: Developmental medicine and child neurology. - 0012-1622. ; 39:8, s. 502-7
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Journal article (peer-reviewed)abstract
- Twenty children with acquired brain injuries were investigated with CT and SPECT. The findings were related to the clinical outcome judged at discharge following acute care after the injury and at follow-up 5 years later. The abnormalities that were found were classified for each lobe on a scale ranging from 0 (normal) to 5 (severe abnormality). The patients were divided into two groups showing mild and severe injury. CT and SPECT revealed similar results in the patients with severe injury, but in the group of mildly injured children the number of affected lobes and scores indicated by SPECT were significantly higher than those indicated by CT. SPECT also differentiated more effectively between the two outcome groups. This supports the hypothesis that SPECT could be used as an instrument to objectivise minor sequelae and that SPECT and CT are both useful methods for forecasting outcome.
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| 12. |
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| 13. |
- Emanuelson, Ingrid, 1955, et al.
(author)
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Occurrence of epilepsy during the first 10 years after traumatic brain injury acquired in childhood up to the age of 18 years in the south western Swedish population-based series.
- 2009
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In: Brain injury : [BI]. - : Informa UK Limited. - 1362-301X .- 0269-9052. ; 23:7, s. 612-6
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Journal article (peer-reviewed)abstract
- BACKGROUND: The risk of seizures is increased after a traumatic brain injury (TBI), but the impact and duration of this increased risk is not well characterized in children. OBJECTIVE: To identify post-traumatic epilepsy (PTE) and post-concussion symptoms 10 years after a TBI during childhood. RESEARCH DESIGN: The study is a population-based retrospective follow-up study. PROCEDURE: Ten years after brain injury all 165 survivors, who as children (<18 years) in 1987-1991 as residents in the south western Swedish health care region had had a TBI, were invited to participate in a follow-up. A questionnaire regarding medical conditions and medication was filled out by the patients themselves or their parents as was a 21-item questionnaire (PCSQ) regarding post-concussion symptoms. Of the surviving 165 individuals, 109 participated (67%). RESULTS: Eight of 109 developed immediate seizures. During the follow-up period 12/109 had developed active epilepsy. Of these 12, five had had immediate seizures. The incidence of developing PTE within 10 years after a TBI was thus in this series 11%. The relative risk to develop late onset post-traumatic epilepsy (> or =1 week after injury) for those who had had immediate seizures was 9.018 (p = 0.0003, 95% CI = 3.69-22.05). CONCLUSIONS: TBI is a relatively rare cause of epilepsy in childhood, although immediate seizures are associated with an increased risk of developing post-traumatic epilepsy.
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| 14. |
- Emanuelson, Ingrid, et al.
(author)
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Quality of life and post-concussion symptoms in adults after mild traumatic brain injury : a population-based study in western Sweden.
- 2003
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In: Acta Neurologica Scandinavica. - 0001-6314 .- 1600-0404. ; 108:5, s. 332-338
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Journal article (peer-reviewed)abstract
- OBJECTIVES: To study quality of life and subjective post-concussion symptoms in adults (16-60 years) with a mild traumatic brain injury (MTBI) 3 months and 1 year after injury. METHODS: Of a total of 489 patients 173 responded to questionnaires at 3 months and at 1 year, including the SF-36 health-related quality of life survey, which is a standardized measure validated for Swedish conditions. Post-concussion symptoms were rated as either existing or non-existing in a 21-item checklist [a modified version of Comprehensive Psychopathological Rating Scale (CPRS)]. RESULTS: SF-36 showed impaired scores in all dimensions. Existing post-concussion symptoms were reported by 1545%. Significantly, more symptoms were present at 3 months than at 3 weeks after injury. Furthermore, a significant correlation between higher rates of post-concussion symptoms and lower SF-36 scores was found. CONCLUSIONS: The SF-36 results were significantly impaired compared with an age- and gender-matched normative control group and the rate of post-concussion symptoms was significantly higher at 3 months than at 3 weeks after injury. As a significant correlation between higher rates of symptoms and low SF-36 scores was also found we assume SF-36 to be a sensitive enough measure of MTBI-related effects.
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| 15. |
- Emanuelson, Ingrid, et al.
(author)
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Traumatic brain injury in children treated at the neurosurgical unit at Sahlgrenska University Hospital in 1987-1991 and 1997-2001: An analysis of the process of care
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Other publication (other academic/artistic)abstract
- Background: In 1992, a new volume targeted treatment, the “Lund Protocol”, was introduced in the field of neurosurgical care at Sahlgrenska University Hospital. The mortality rate for adults dropped markedly while the number of patients in a vegetative state remained at the same level. As yet, changes in mortality and outcome for children have not been investigated in detail. Aim: To describe the causes and severity of injury, process of care from emergency care to rehabilitation, and the rate of received rehabilitation and to follow-up two cohorts treated for child traumatic brain injury (CTBI) before and after the initiation of the “Lund Protocol”. For group 2, treated after the initiation of the “Lund Protocol” an additional aim was to relate brain injury severity parameters in the acute care stage to functional outcome. Methods: A retrospective population-based study of patient records of former paediatric patients treated neurosurgically for CTBI between 1987-1991 and 1997-2001. Epidemiological results are presented as descriptive statistics. To evaluate the relationship between brain injury parameters and outcome an exploratory cluster analysis was performed on the data from group 2. Results: For both groups traffic accidents were the most common cause of injury. The Glasgow Coma Scale indicated a more severe injury level in group1. The mortality rate in group1 was 8 % compared with 2 % in group 2 (n.s.). The Glasgow outcome score was on the same level (median 5), and the rate of received rehabilitation was equally low in both groups, 27 % versus 33 %. The cluster analysis revealed that length of care and time in a respirator had a stronger relationship with outcome than the Reaction Level Scale (RLS). Conclusion: There is still no stable process of care after CTBI as 67 % in the later treated group did not receive rehabilitation and 50 % of those did not receive any medical check- ups in the long- term perspective.
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| 16. |
- Ginstfeldt, Tim, et al.
(author)
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An overview of attention deficits after paediatric traumatic brain injury.
- 2010
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In: Brain injury : [BI]. - : Informa UK Limited. - 1362-301X .- 0269-9052. ; 24:10, s. 1123-34
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Journal article (peer-reviewed)abstract
- Attention could be categorized into sustained, selective, shifting, divided and attention span. The primary objective was to evaluate the type of attention deficits that occurs after paediatric traumatic brain injury.
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| 17. |
- Hansson, Ingrid, et al.
(author)
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Occurrence of Campylobacter spp. in Swedish calves, common sequence types and antibiotic resistance patterns
- 2021
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In: Journal of Applied Microbiology. - : Oxford University Press (OUP). - 1364-5072 .- 1365-2672. ; 130, s. 2111-2122
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Journal article (peer-reviewed)abstract
- Aims Cattle are the second most important cause of human campylobacteriosis, after poultry, but there are knowledge gaps regarding Campylobacter in cattle. This study examined the occurrence of Campylobacter, the species present, sequence types and antibiotic resistance in Swedish cattle.Methods and Results Faeces samples collected from 154 calves on seven Swedish farms, and 69 follow-up samples from a second collection occasion, were analysed. Campylobacter were isolated from 77% of calves at the first sampling, with Campylobacter jejuni as the most frequently isolated species. Animals kept on deep straw bedding were less likely to be colonized with Campylobacter. Whole-genome sequencing of 90 C. jejuni samples resulted in 11 sequence types, among which ST-19 and ST-21 were most frequent. Antimicrobial resistance analyses showed that 46% of 142 isolates analysed were resistant to quinolones, while all isolates belonging to ST-19, ST-22 and ST-441 were resistant to ciprofloxacin and nalidixic acid.Conclusions Campylobacter jejuni was the species most frequently isolated in calves and a strong association was found between sequence type and antimicrobial resistance pattern.Significance and Impact of the Study The high proportion of calves with quinolone-resistant Campylobacter jejuni should be considered in a One Health perspective.
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| 18. |
- Holmqvist Andersson, Elisabeth, et al.
(author)
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Epidemiology of traumatic brain injury : a population based study in western Sweden.
- 2003
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In: Acta Neurologica Scandinavica. - 0001-6314 .- 1600-0404. ; 107:4, s. 256-259
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Journal article (peer-reviewed)abstract
- BACKGROUND: This study on traumatic brain injury (TBI) is based on prospective and retrospective population based data from a head injury register in Boras. METHODS: Data was collected from the hospital emergency unit, the discharge register, the regional neurosurgical clinic and the coroner's records during 1 year. This district is mixed urban and rural with a population of 138 000. RESULTS: The 753 cases identified represent an incidence of 546 per 100 000 which includes deaths (0.7%), hospital admissions (67%) and attendance at the emergency department in patients not admitted (32%). Males (644 per 100 000), had 1.46 higher overall rate than females (442 per 100 000). The external causes were dominated by fall from same level (31%) and fall from different level (27%) followed by traffic accidents (16%) and persons hit by objects (15%). CONCLUSIONS: The incidence of TBI found in this study is high but well in accordance with earlier published Swedish studies.
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| 19. |
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| 20. |
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| 21. |
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| 22. |
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| 23. |
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| 24. |
- Horneman, Göran, 1945, et al.
(author)
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Cognitive outcome in children and young adults who sustained severe and moderate traumatic brain injury 10 years earlier.
- 2009
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In: Brain injury : [BI]. - : Informa UK Limited. - 1362-301X .- 0269-9052. ; 23:11, s. 907-14
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Journal article (peer-reviewed)abstract
- OBJECTIVE: This study is a population-based, retrospective follow-up study of neuropsychological functions after severe and moderate TBI. METHODS: One hundred and sixty-five survivors of TBI injured in 1987-1991 in the 0-17-year age group were identified. Of the traceable individuals (149), 53 patients who sustained injury at a mean of 9.96 years participated in a neuropsychological investigation 10 years post-injury. A control group of 40 healthy subjects, matched for age and sex was chosen. An extensive neuropsychological test battery was used. RESULTS: The TBI group showed significantly poorer performance in tests of intellectual function, with substantially lower results in verbal tests and in tests of verbal learning and memory, visuo-constructive ability and executive functions. The severely injured group showed substantial recovery. Poor results in visuo-constructive tests and tests of executive functions remained. CONCLUSIONS: Severity of injury is an important factor when assessing outcome, even 10 years after childhood TBI. The TBI group obtained poorer results on most of the measurements compared with healthy controls. Verbal function was strongly affected which needs to be taken into consideration when preparing for rehabilitation programmes. Evaluations of final outcome should not be made before the subjects reach adulthood.
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| 25. |
- Horneman, G., et al.
(author)
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Health-related quality of life of adolescents and young adults 10 years after serious traumatic brain injury
- 2005
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In: International Journal of Rehabilitation Research. - : Ovid Technologies (Wolters Kluwer Health). - 0342-5282 .- 1473-5660. ; 28:3, s. 245-9
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Journal article (peer-reviewed)abstract
- The aim of this study was to investigate health-related quality of life (HRQoL) in a population-based group of young adults with serious traumatic brain injury (TBI) acquired 10 years earlier. In the time period 1987--1991, all 165 residents (<18 years of age) in the south-western health care region of Sweden who had suffered a serious TBI were followed up. Of these, 109 (67%) participated in this follow-up study, which was conducted using the 15-dimension (15D) HRQoL instrument. Their HRQoL was compared with that of 1,039 individuals drawn randomly from the National Population Register for the Finnish Health Care Survey 1995/1996 and matched for age and sex. Nine (mobility, vision, hearing, eating, speech, mental status, depression, distress and usual activities) of the 15 dimensions were significantly aberrant in the TBI group. This TBI group differed markedly from children with organ transplantation, as the transplantation children did not differ from a control group in terms of HRQoL. Compared with other groups of children with congenital or long-lasting conditions, the TBI group had more medical and mental problems.
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| 26. |
- Nilsson, Johanna, et al.
(author)
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Childhood traumatic brain injury; education and medical disability
- 2014
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In: Social Care and Neurodisability. - 2042-0919. ; 5:3, s. 171-183
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Journal article (peer-reviewed)abstract
- Purpose – The purpose of this paper is to describe level of education and return to school and employment among children and young adults who sustained a Traumatic brain injury (TBI) 15 years ago and to analyse the occurrence of any medical disability. Design/methodology/approach – The study is descriptive. The authors used a questionnaire with questions covering education, employment, sick leave, insurance compensation and medical follow-up. Findings – A total of 37 individuals, 17 (45.9 per cent) women and 20 (54.1 per cent) men, participated. Just over half (20 individuals, 54.1 per cent) were in employment, five (13.5 per cent) were unemployed and four (10.8 per cent) received disability pension. In total, 18 (48.6 per cent) individuals had received full compensation from their insurance companies, while 12 (35.3 per cent) had had their medical disability classified. A total of 12 (33.3 per cent) individuals were taking medication and five (13.9 per cent) had been followed by the health care system. The results indicate that people sustaining a TBI are less successful on the labour market than the general population, that relatively few had had their disability classified and that almost 50 per cent receive no insurance compensation. Originality/value – There are few long-term follow-up studies on brain injuries acquired during childhood, and this study would add to the previous knowledge, as aspects of medical disability and legal compensation are included. © Emerald Group Publishing Limited.
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| 27. |
- Renström, Barbro, et al.
(author)
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Self-reported health and influence on life situation 5–8 years after paediatric traumatic brain injury
- 2012
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In: Brain Injury. - : Informa Healthcare. - 0269-9052 .- 1362-301X. ; 26:12, s. 1405-1414
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Journal article (peer-reviewed)abstract
- Primary objective : During childhood, the central nervous system is in a state of rapid development which can be interrupted by a traumatic brain injury (TBI). This study aimed to describe if and how TBI during childhood influences health and life situation, 5–8 years later.Research design : A case-control retrospective design was employed for the assessment of 61 adolescents and young adults with a mild, moderate or severe TBI and 229 matched controls from a normative group (16–24 years).Methods and procedures : SF-36 (Short Form 36 health survey) and a self-reported questionnaire measuring life situation were distributed to youths suffering TBI 5–8 years ago. Forty-five youths (74%) completed the questionnaires.Main outcomes and results : Participants with a TBI stated lower self-estimated health compared with the normative group.Remaining self-reported symptoms were physical and cognitive. Negative effects of TBI influencing school results, leisure activities and thoughts about future life situation were also described.Conclusion : Young individuals experience sustained negative effects of childhood TBI on health and life situation. More research is necessary to detect, understand and properly support these youths.
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| 28. |
- Sabel, Magnus, 1966, et al.
(author)
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Active video gaming improves body coordination in survivors of childhood brain tumours.
- 2016
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In: Disability and rehabilitation. - : Informa UK Limited. - 1464-5165 .- 0963-8288. ; 38:21, s. 2073-2084
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Journal article (peer-reviewed)abstract
- Purpose We investigated whether active video gaming (AVG) could bring about regular, enjoyable, physical exercise in children treated for brain tumours, what level of physical activity could be reached and if the children's physical functioning improved. Methods Thirteen children, aged 7-17 years, were randomised to either AVG or waiting-list. After 10-12 weeks they crossed-over. Weekly Internet coaching sessions were used to sustain motivation and evaluate enjoyment. Energy expenditure (EE) levels were measured as Metabolic Equivalent of Task (MET), using a multisensory activity monitor. Single-blinded assessments of physical functioning were done, using the Bruininks-Osteretsky Test of Motor Performance, second edition, evaluating participants before and after the intervention period, as well as comparing the randomisation groups after the first period. Results All patients completed the study. AVG sessions (mean duration 47minutes) were performed on 72% of all days. Mean EE level during AVG sessions was 3.0 MET, corresponding to moderate physical activity. The Body Coordination score improved by 15% (p=0.021) over the intervention period. Conclusions In this group of childhood brain tumour survivors, home-based AVG, supported by a coach, was a feasible, enjoyable and moderately intense form of exercise that improved Body Coordination. Implications for Rehabilitation Childhood brain tumour survivors frequently have cognitive problems, inferior physical functioning and are less physically active compared to their healthy peers. Active video gaming (AVG), supported by Internet coaching, is a feasible home-based intervention in children treated for brain tumours, promoting enjoyable, regular physical exercise of moderate intensity. In this pilot study, AVG with Nintendo Wii improved Body Coordination.
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| 29. |
- Sabel, Magnus, 1966, et al.
(author)
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Effects of physically active video gaming on cognition and activities of daily living in childhood brain tumor survivors: a randomized pilot study
- 2017
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In: Neuro Oncology Practice. - : Oxford University Press (OUP). - 2054-2577 .- 2054-2585. ; 4:2, s. 98-110
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Journal article (peer-reviewed)abstract
- Background. Physical activity can enhance cognitive functions in both animals and humans. We hypothesized that physically active video gaming could: i) improve cognitive functions and ii) improve the execution of activities of daily living among survivors of childhood brain tumors.Methods. Children 7 to 17 years old who completed treatment, including radiotherapy, for a brain tumor 1 to 5 years earlier were randomized to either intervention or waiting list. After 10 to 12 weeks the groups crossed over. The intervention consisted of active video gaming, using a motion-controlled video console (Nintendo Wii), for a minimum of 30 minutes a day, 5 days a week and weekly Internet-based coaching sessions. Evaluations before and after each period included tests of the execution of activities of daily living, using the Assessment of Motor and Process Skills (AMPS) and cognitive tests. Test scores before and after the intervention were compared. A parallel group comparison was performed as a sensitivity analysis.Results. All 13 children enrolled completed the program. Compared to baseline, the motor (P= .012) and process (P=.002) parts of AMPS improved significantly after active video gaming. In the parallel group analysis the improvement in the process part of AMPS remained statistically significant (P= .029), but not the change in AMPS motor score (P= .059). No significant change was found in cognitive tests although there were trends for improvement in sustained attention (P = .090) and selective attention (P = .078).Conclusion. In this pilot study, active video gaming used as a home-based intervention for childhood brain tumor survivors improved motor and process skills in activities of daily living.
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| 30. |
- Saury, Jean-Michel, 1951, et al.
(author)
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Cognitive consequences of the treatment of medulloblastoma among children.
- 2011
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In: Pediatric neurology. - : Elsevier BV. - 1873-5150 .- 0887-8994. ; 44:1, s. 21-30
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Journal article (peer-reviewed)abstract
- Progress in the treatment of medulloblastoma has resulted in increased survival among children. However, effective treatment, especially radiation therapy, produces negative consequences in the cognitive development of children, in terms of decreased intelligence quotients. Determining the factors underlying this decrease may influence the types of rehabilitation needed by children who undergo treatment for medulloblastoma. We review recent research on the impact of some factors that may underlie the cognitive deficits of pediatric and adolescent survivors, i.e., verbal comprehension, perceptual organization, attention, and processing speed. We assess eight pediatric survivors of medulloblastoma treatment with surgery, radiation, and chemotherapy. Children were assessed twice after diagnosis, using the Wechsler Intelligence Scale for Children-Third Edition. A large decrease in cognitive capacity was evident, as measured by intelligence quotients and factor indices. A raw score analysis of 12 subtests was performed, indicating a slower acquisition of functions and knowledge in the domains of verbal comprehension, perceptual organization, social perception, and psychomotor skills. We discuss issues of social reintegration, and propose that the rehabilitation of pediatric patients must include a program for social reinsertion, in addition to psychoeducational support.
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| 31. |
- Saury, J. M., et al.
(author)
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Neuropsychological Assessment of Hippocampal Integrity
- 2017
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In: Appl Neuropsychol Adult. - : Informa UK Limited. - 2327-9095 .- 2327-9109. ; 24:2, s. 140-151
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Journal article (peer-reviewed)abstract
- Finding methods to describe subcortical processes assisting cognition is an important concern for clinical neuropsychological practice. In this study, we reviewed the literature concerning the relationship between a neuropsychological instrument and the underlying neural substructure. We examined evidence indicating that one of the oldest neuropsychological tests still in use, the Rey Auditory Verbal Learning Test (RAVLT), includes reliable indicators of hippocampal integrity. We reviewed studies investigating the neural structures underlying seven tasks generated by the RAVLT, from the perspective of whether the performance of these tasks is dependent on the hippocampus. We found support for our hypothesis in five cases: learning capacity, proactive interference, immediate recall, delayed recall, and delayed recognition. No support for our hypothesis was found with regard to short-term memory and retroactive interference. The RAVLT appears to be a reliable tool for assessing the integrity of the hippocampus and for the early detection of dysfunction. There is a need for such assessments, due to the crucial role of the hippocampus in cognition, for instance, in terms of predicting future outcomes.
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- Sörbo, Ann, 1955, et al.
(author)
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Outcome after severe brain damage, what makes the difference?
- 2005
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In: Brain Inj. ; 19:7, s. 493-503
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Journal article (peer-reviewed)abstract
- OBJECTIVE: To assess and compare the consequences for outcome in terms of the dimensions of activity and participation for two groups: group A, which received early formalized rehabilitation, and group B, which received late or no formalized rehabilitation. RESEARCH DESIGN: A cross-sectional study. PROCEDURE: Twenty-six patients (A: n = 14 and B: n = 12) with severe brain damage were included. The participants were assessed a mean of 26.6 months (SD 7.1, median 25, range 14-41) after the incident using the structured form for the Swedish Neuro database, the Glasgow Outcome Scale (GOS), the Extended Glasgow Outcome Scale (GOSE) and the Functional Independence Measure (FIM). RESULTS: The study reveals a better outcome for group A. No patient remained in a vegetative state in group A as compared with three in group B. In group A, 50% were independent as compared with 17% in group B. The frequency of return to work was 43% in group A, but no patient in group B had returned to work.
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