| 1. |
- Arndt, D. S., et al.
(author)
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State of the Climate in 2016
- 2017
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In: Bulletin of The American Meteorological Society - (BAMS). - 0003-0007 .- 1520-0477. ; 98:8, s. S1-S280
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Journal article (peer-reviewed)abstract
- In 2016, the dominant greenhouse gases released into Earth's atmosphere-carbon dioxide, methane, and nitrous oxide-continued to increase and reach new record highs. The 3.5 +/- 0.1 ppm rise in global annual mean carbon dioxide from 2015 to 2016 was the largest annual increase observed in the 58-year measurement record. The annual global average carbon dioxide concentration at Earth's surface surpassed 400 ppm (402.9 +/- 0.1 ppm) for the first time in the modern atmospheric measurement record and in ice core records dating back as far as 800000 years. One of the strongest El Nino events since at least 1950 dissipated in spring, and a weak La Nina evolved later in the year. Owing at least in part to the combination of El Nino conditions early in the year and a long-term upward trend, Earth's surface observed record warmth for a third consecutive year, albeit by a much slimmer margin than by which that record was set in 2015. Above Earth's surface, the annual lower troposphere temperature was record high according to all datasets analyzed, while the lower stratospheric temperature was record low according to most of the in situ and satellite datasets. Several countries, including Mexico and India, reported record high annual temperatures while many others observed near-record highs. A week-long heat wave at the end of April over the northern and eastern Indian peninsula, with temperatures surpassing 44 degrees C, contributed to a water crisis for 330 million people and to 300 fatalities. In the Arctic the 2016 land surface temperature was 2.0 degrees C above the 1981-2010 average, breaking the previous record of 2007, 2011, and 2015 by 0.8 degrees C, representing a 3.5 degrees C increase since the record began in 1900. The increasing temperatures have led to decreasing Arctic sea ice extent and thickness. On 24 March, the sea ice extent at the end of the growth season saw its lowest maximum in the 37-year satellite record, tying with 2015 at 7.2% below the 1981-2010 average. The September 2016 Arctic sea ice minimum extent tied with 2007 for the second lowest value on record, 33% lower than the 1981-2010 average. Arctic sea ice cover remains relatively young and thin, making it vulnerable to continued extensive melt. The mass of the Greenland Ice Sheet, which has the capacity to contribute similar to 7 m to sea level rise, reached a record low value. The onset of its surface melt was the second earliest, after 2012, in the 37-year satellite record. Sea surface temperature was record high at the global scale, surpassing the previous record of 2015 by about 0.01 degrees C. The global sea surface temperature trend for the 21st century-to-date of +0.162 degrees C decade(-1) is much higher than the longer term 1950-2016 trend of +0.100 degrees C decade(-1). Global annual mean sea level also reached a new record high, marking the sixth consecutive year of increase. Global annual ocean heat content saw a slight drop compared to the record high in 2015. Alpine glacier retreat continued around the globe, and preliminary data indicate that 2016 is the 37th consecutive year of negative annual mass balance. Across the Northern Hemisphere, snow cover for each month from February to June was among its four least extensive in the 47-year satellite record. Continuing a pattern below the surface, record high temperatures at 20-m depth were measured at all permafrost observatories on the North Slope of Alaska and at the Canadian observatory on northernmost Ellesmere Island. In the Antarctic, record low monthly surface pressures were broken at many stations, with the southern annular mode setting record high index values in March and June. Monthly high surface pressure records for August and November were set at several stations. During this period, record low daily and monthly sea ice extents were observed, with the November mean sea ice extent more than 5 standard deviations below the 1981-2010 average. These record low sea ice values contrast sharply with the record high values observed during 2012-14. Over the region, springtime Antarctic stratospheric ozone depletion was less severe relative to the 1991-2006 average, but ozone levels were still low compared to pre-1990 levels. Closer to the equator, 93 named tropical storms were observed during 2016, above the 1981-2010 average of 82, but fewer than the 101 storms recorded in 2015. Three basins-the North Atlantic, and eastern and western North Pacific-experienced above-normal activity in 2016. The Australian basin recorded its least active season since the beginning of the satellite era in 1970. Overall, four tropical cyclones reached the Saffir-Simpson category 5 intensity level. The strong El Nino at the beginning of the year that transitioned to a weak La Nina contributed to enhanced precipitation variability around the world. Wet conditions were observed throughout the year across southern South America, causing repeated heavy flooding in Argentina, Paraguay, and Uruguay. Wetter-than-usual conditions were also observed for eastern Europe and central Asia, alleviating the drought conditions of 2014 and 2015 in southern Russia. In the United States, California had its first wetter-than-average year since 2012, after being plagued by drought for several years. Even so, the area covered by drought in 2016 at the global scale was among the largest in the post-1950 record. For each month, at least 12% of land surfaces experienced severe drought conditions or worse, the longest such stretch in the record. In northeastern Brazil, drought conditions were observed for the fifth consecutive year, making this the longest drought on record in the region. Dry conditions were also observed in western Bolivia and Peru; it was Bolivia's worst drought in the past 25 years. In May, with abnormally warm and dry conditions already prevailing over western Canada for about a year, the human-induced Fort McMurray wildfire burned nearly 590000 hectares and became the costliest disaster in Canadian history, with $3 billion (U.S. dollars) in insured losses.
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| 2. |
- Menkveld, Albert J., et al.
(author)
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Nonstandard Errors
- 2024
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In: JOURNAL OF FINANCE. - : Wiley-Blackwell. - 0022-1082 .- 1540-6261. ; 79:3, s. 2339-2390
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Journal article (peer-reviewed)abstract
- In statistics, samples are drawn from a population in a data-generating process (DGP). Standard errors measure the uncertainty in estimates of population parameters. In science, evidence is generated to test hypotheses in an evidence-generating process (EGP). We claim that EGP variation across researchers adds uncertainty-nonstandard errors (NSEs). We study NSEs by letting 164 teams test the same hypotheses on the same data. NSEs turn out to be sizable, but smaller for more reproducible or higher rated research. Adding peer-review stages reduces NSEs. We further find that this type of uncertainty is underestimated by participants.
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| 3. |
- Arndt, D. S., et al.
(author)
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STATE OF THE CLIMATE IN 2017
- 2018
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In: Bulletin of The American Meteorological Society - (BAMS). - : American Meteorological Society. - 0003-0007 .- 1520-0477. ; 99:8, s. S1-S310
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Research review (peer-reviewed)
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| 4. |
- Beal, Jacob, et al.
(author)
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Robust estimation of bacterial cell count from optical density
- 2020
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In: Communications Biology. - : Springer Science and Business Media LLC. - 2399-3642. ; 3:1
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Journal article (peer-reviewed)abstract
- Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data.
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| 5. |
- Algaba, Juan-Carlos, et al.
(author)
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Broadband Multi-wavelength Properties of M87 during the 2017 Event Horizon Telescope Campaign
- 2021
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In: Astrophysical Journal Letters. - : American Astronomical Society. - 2041-8213 .- 2041-8205. ; 911:1
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Research review (peer-reviewed)abstract
- In 2017, the Event Horizon Telescope (EHT) Collaboration succeeded in capturing the first direct image of the center of the M87 galaxy. The asymmetric ring morphology and size are consistent with theoretical expectations for a weakly accreting supermassive black hole of mass ∼6.5 × 109 M o˙. The EHTC also partnered with several international facilities in space and on the ground, to arrange an extensive, quasi-simultaneous multi-wavelength campaign. This Letter presents the results and analysis of this campaign, as well as the multi-wavelength data as a legacy data repository. We captured M87 in a historically low state, and the core flux dominates over HST-1 at high energies, making it possible to combine core flux constraints with the more spatially precise very long baseline interferometry data. We present the most complete simultaneous multi-wavelength spectrum of the active nucleus to date, and discuss the complexity and caveats of combining data from different spatial scales into one broadband spectrum. We apply two heuristic, isotropic leptonic single-zone models to provide insight into the basic source properties, but conclude that a structured jet is necessary to explain M87's spectrum. We can exclude that the simultaneous γ-ray emission is produced via inverse Compton emission in the same region producing the EHT mm-band emission, and further conclude that the γ-rays can only be produced in the inner jets (inward of HST-1) if there are strongly particle-dominated regions. Direct synchrotron emission from accelerated protons and secondaries cannot yet be excluded.
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| 6. |
- Kehoe, Laura, et al.
(author)
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Make EU trade with Brazil sustainable
- 2019
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In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 364:6438, s. 341-
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Journal article (other academic/artistic)
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| 7. |
- Bousquet, Jean, et al.
(author)
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ARIA digital anamorphosis : Digital transformation of health and care in airway diseases from research to practice
- 2021
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In: Allergy. European Journal of Allergy and Clinical Immunology. - : John Wiley & Sons. - 0105-4538 .- 1398-9995. ; 76:1, s. 168-190
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Research review (peer-reviewed)abstract
- Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed.
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| 8. |
- Falster, Daniel, et al.
(author)
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AusTraits, a curated plant trait database for the Australian flora
- 2021
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In: Scientific Data. - : Nature Portfolio. - 2052-4463. ; 8:1
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Journal article (peer-reviewed)abstract
- We introduce the AusTraits database - a compilation of values of plant traits for taxa in the Australian flora (hereafter AusTraits). AusTraits synthesises data on 448 traits across 28,640 taxa from field campaigns, published literature, taxonomic monographs, and individual taxon descriptions. Traits vary in scope from physiological measures of performance (e.g. photosynthetic gas exchange, water-use efficiency) to morphological attributes (e.g. leaf area, seed mass, plant height) which link to aspects of ecological variation. AusTraits contains curated and harmonised individual- and species-level measurements coupled to, where available, contextual information on site properties and experimental conditions. This article provides information on version 3.0.2 of AusTraits which contains data for 997,808 trait-by-taxon combinations. We envision AusTraits as an ongoing collaborative initiative for easily archiving and sharing trait data, which also provides a template for other national or regional initiatives globally to fill persistent gaps in trait knowledge.
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| 9. |
- Farrell, Edward D. D., et al.
(author)
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A baseline for the genetic stock identification of Atlantic herring, Clupea harengus, in ICES Divisions 6.a, 7.b-c
- 2022
-
In: Royal Society Open Science. - : The Royal Society. - 2054-5703. ; 9:9
-
Journal article (peer-reviewed)abstract
- Atlantic herring in International Council for Exploration of the Sea (ICES) Divisions 6.a, 7.b-c comprises at least three populations, distinguished by temporal and spatial differences in spawning, which have until recently been managed as two stocks defined by geographical delineators. Outside of spawning the populations form mixed aggregations, which are the subject of acoustic surveys. The inability to distinguish the populations has prevented the development of separate survey indices and separate stock assessments. A panel of 45 single-nucleotide polymorphisms, derived from whole-genome sequencing, were used to genotype 3480 baseline spawning samples (2014-2021). A temporally stable baseline comprising 2316 herring from populations known to inhabit Division 6.a was used to develop a genetic assignment method, with a self-assignment accuracy greater than 90%. The long-term temporal stability of the assignment model was validated by assigning archive (2003-2004) baseline samples (270 individuals) with a high level of accuracy. Assignment of non-baseline samples (1514 individuals) from Divisions 6.a, 7.b-c indicated previously unrecognized levels of mixing of populations outside of the spawning season. The genetic markers and assignment models presented constitute a 'toolbox' that can be used for the assignment of herring caught in mixed survey and commercial catches in Division 6.a into their population of origin with a high level of accuracy.
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| 21. |
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| 23. |
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| 24. |
- Adams, C. B., et al.
(author)
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Observation of the Gamma-Ray Binary HESS J0632+057 with the HESS, MAGIC, and VERITAS Telescopes
- 2021
-
In: Astrophysical Journal. - : Institute of Physics Publishing (IOPP). - 0004-637X .- 1538-4357. ; 923:2
-
Journal article (peer-reviewed)abstract
- The results of gamma-ray observations of the binary system HESS J0632 + 057 collected during 450 hr over 15 yr, between 2004 and 2019, are presented. Data taken with the atmospheric Cherenkov telescopes H.E.S.S., MAGIC, and VERITAS at energies above 350 GeV were used together with observations at X-ray energies obtained with Swift-XRT, Chandra, XMM-Newton, NuSTAR, and Suzaku. Some of these observations were accompanied by measurements of the H alpha emission line. A significant detection of the modulation of the very high-energy gamma-ray fluxes with a period of 316.7 +/- 4.4 days is reported, consistent with the period of 317.3 +/- 0.7 days obtained with a refined analysis of X-ray data. The analysis of data from four orbital cycles with dense observational coverage reveals short-timescale variability, with flux-decay timescales of less than 20 days at very high energies. Flux variations observed over a timescale of several years indicate orbit-to-orbit variability. The analysis confirms the previously reported correlation of X-ray and gamma-ray emission from the system at very high significance, but cannot find any correlation of optical H alpha parameters with fluxes at X-ray or gamma-ray energies in simultaneous observations. The key finding is that the emission of HESS J0632 + 057 in the X-ray and gamma-ray energy bands is highly variable on different timescales. The ratio of gamma-ray to X-ray flux shows the equality or even dominance of the gamma-ray energy range. This wealth of new data is interpreted taking into account the insufficient knowledge of the ephemeris of the system, and discussed in the context of results reported on other gamma-ray binary systems.
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| 25. |
- Altimiras, Jordi, 1967-, et al.
(author)
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Gastrointestinal blood flow and postprandial metabolism in swimming sea bass dicentrarchus labrax
- 2008
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In: Physiological and Biochemical Zoology. - : University of Chicago Press. - 1522-2152 .- 1537-5293. ; 81:5, s. 663-672
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Journal article (peer-reviewed)abstract
- In trout and salmon, the metabolic costs of exercise and feeding are additive, which would suggest that gastrointestinal blood flow during exercise is maintained to preserve digestive and absorptive processes related to the specific dynamic action (SDA) of food. However, in most published studies, gastrointestinal blood flow drops during swimming, hypoxia, and general stress. To test whether gastrointestinal blood flow is spared during exercise after feeding, sea bass were instrumented with flow probes to measure cardiac output and celiacomesenteric blood flow while swimming in a respirometer before and after feeding. Swimming at 2 body lengths per second (bl s-1) increased metabolic rate considerably more than did feeding (208% vs. 32% increase, respectively, relative to resting), and a similar pattern was observed for cardiac output. In unfed fish, resting gastrointestinal blood flow was mL 13.8 ± 0.5 min-1 kg-1. After feeding, resting gastrointestinal blood flow increased by 82% but then decreased progressively with increasing swimming speeds. At 2 bl s-1, gastrointestinal blood flow in fed fish was not significantly different compared with that in unfed swimming fish, and, therefore, the data do not support the gastrointestinal sparing hypothesis. The magnitude of the SDA was maintained despite the decrease in gastrointestinal blood flow and the consequent reduction in oxygen supply to the gut. An estimate of maximal oxygen flow to the gastrointestinal tract after feeding yielded 2.6 mmol O2 h-1 kg-1, but this amount is not able to cover the oxygen demand of 3.16 mmol O2 h -1 kg-1. Therefore, the SDA must reflect metabolic processes in tissues other than those directly perfused by the celiacomesenteric artery. © 2008 by The University of Chicago. All rights reserved.
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| 26. |
- Bousquet, J. Jean, et al.
(author)
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Next-generation ARIA care pathways for rhinitis and asthma : a model for multimorbid chronic diseases
- 2019
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In: Clinical and Translational Allergy. - : BMC. - 2045-7022. ; 9
-
Research review (peer-reviewed)abstract
- Background: In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy.Main body: As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted "patient activation", (ii) Implementation of care pathways by pharmacists and (iii) Next-generation guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Sante as a Good Practice in the field of digitally-enabled, integrated, person-centred care.Conclusion: In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement.
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| 27. |
- Capel, Pierre, et al.
(author)
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Effective field theory analysis of the Coulomb breakup of the one-neutron halo nucleus 19 C
- 2023
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In: European Physical Journal A. - 1434-601X .- 1434-6001. ; 59:11
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Journal article (peer-reviewed)abstract
- We analyse the Coulomb breakup of 19 C measured at 67A MeV at RIKEN. We use the Coulomb-Corrected Eikonal (CCE) approximation to model the reaction and describe the one-neutron halo nucleus 19 C within Halo Effective Field Theory (Halo EFT). At leading order we obtain a fair reproduction of the measured cross section as a function of energy and angle. The description is insensitive to the choice of optical potential, as long as it accurately represents the size of 18 C. It is also insensitive to the interior of the 19 C wave function. Comparison between theory and experiment thus enables us to infer asymptotic properties of the ground state of 19 C: these data put constraints on the one-neutron separation energy of this nucleus and, for a given binding energy, can be used to extract an asymptotic normalisation coefficient (ANC). These results are confirmed by CCE calculations employing next-to-leading order Halo EFT descriptions of 19 C: at this order the results for the Coulomb breakup cross section are completely insensitive to the choice of the regulator. Accordingly, this reaction can be used to constrain the one-neutron separation energy and ANC of 19 C.
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| 28. |
- Egginton, S., et al.
(author)
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Maximum cardiac performance of Antarctic fishes that lack haemoglobin and myoglobin: exploring the effect of warming on nature's natural knockouts
- 2019
-
In: Conservation Physiology. - : Oxford University Press (OUP). - 2051-1434. ; 7
-
Journal article (peer-reviewed)abstract
- Antarctic notothenioids, some of which lack myoglobin (Mb) and/or haemoglobin (Hb), are considered extremely stenothermal, which raises conservation concerns since Polar regions are warming at unprecedented rates. Without reliable estimates of maximum cardiac output (((Q)over dot)), it is impossible to assess their physiological scope in response to warming seas. Therefore, we compared cardiac performance of two icefish species, Chionodraco rastrospinosus (Hb(-)Mb(+)) and Chaenocephalus aceratus (Hb(-)Mb(-)), with a related notothenioid, Notothenia coriiceps (Hb(+)Mb(+)) using an in situ perfused heart preparation. The maximum (Q)over dot, heart rate (f(H)), maximum cardiac work (WC) and relative ventricular mass of N. coriiceps at 1 degrees C were comparable to temperate-water teleosts, and acute warming to 4 degrees C increased fH and WC, as expected. In contrast, icefish hearts accommodated a higher maximum stroke volume (VS) and maximum. Q at 1 degrees C, but their unusually large hearts had a lower fH and maximum afterload tolerance than N. coriiceps at 1 degrees C. Furthermore, maximum VS, maximum. Q and fH were all significantly higher for the Hb(-)Mb(+) condition compared with the Hb(-)Mb(-) condition, a potential selective advantage when coping with environmental warming. Like N. coriiceps, both icefish species increased H-f at 4 degrees C. Acutely warming C. aceratus increased maximum (Q) over dot, while C. rastrospinosus (like N. coriiceps) held at 4 degrees C for 1 week maintained maximum. Q when tested at 4 degrees C. These experiments involving short-term warming should be followed up with long-term acclimation studies, since the maximum cardiac performance of these three Antarctic species studied seem to be tolerant of temperatures in excess of predictions associated with global warming.
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| 29. |
- Farrell, A. P., et al.
(author)
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Maximum cardiac performance and adrenergic sensitivity of the sea bass at high temperatures
- 2007
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In: Journal of Experimental Biology. - : The Company of Biologists. - 1477-9145 .- 0022-0949. ; 210, s. 1216-1224
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Journal article (peer-reviewed)abstract
- We examined maximum cardiac performance of sea bass Dicentrarchus labrax acclimated to 18°C and 22°C, temperatures near the optimum for growth of this species. Our aim was to study whether cardiac performance, especially the effect of adrenergic stimulation, differed when compared to salmonids. Sea bass and salmonids are both athletic swimmers but their cardiac anatomy differs markedly. The sea bass ventricle does not receive any oxygenated blood via a coronary circulation while salmonids have a well-developed arterial supply of oxygen to the compact layer of the ventricle. Using in situ perfused heart preparations, maximum cardiac performance of 18°C-acclimated sea bass (i.e. cardiac output=90.8± 6.6 ml min–1 kg–1 and power output=11.41±0.83 mW g–1) was found to be comparable to that previously reported for rainbow trout Oncorhynchus mykiss and brown trout Salmo trutta at similar temperatures and with tonic adrenergic (5 nmol l–1 adrenaline) stimulation. For 22°C-acclimated sea bass, heart rate was significantly higher, but maximum stroke volume was reduced by 22% (1.05±0.05 ml kg–1) compared with 18°C (1.38± 0.11 ml kg–1). As a result, maximum cardiac output (99.4±3.9 ml min–1 kg–1) was not significantly different at 22°C. Instead, maximum power output was 27% higher at 22°C (14.95±0.96 mW g–1) compared with 18°C, primarily because of the smaller relative ventricular mass in 22°C-acclimated sea bass. Compared with tonic adrenergic stimulation with 5 nmol l–1 adrenaline, maximum adrenergic stimulation of the sea bass heart produced only modest stimulatory effects at both temperatures (12–13% and 14–15% increases in maximum cardiac output and power output, respectively, with no chronotropic effect). Adrenergic stimulation also increased the cardiac sensitivity to filling pressure, with the maximum left-shift in the Starling curve being produced by 50–100 nmol l–1 adrenaline at 18°C and 10–50 nmol l–1 adrenaline at 22°C. We show that the sea bass, which lacks a coronary arterial oxygen supply to the ventricle, has a powerful heart. Its maximum performance is comparable to a salmonid heart, as is the modest stimulatory effect of adrenaline at high temperature.
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| 30. |
- Farrell, Anthony P., et al.
(author)
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Maximum cardiac performance and adrenergic sensitivity of the sea bass Dicentrarchus labrax at high temperatures
- 2007
-
In: Journal of Experimental Biology. - : The Company of Biologists. - 0022-0949 .- 1477-9145. ; 210, s. 1216-1224
-
Journal article (peer-reviewed)abstract
- We examined maximum cardiac performance of sea bass Dicentrarchus labrax acclimated to 18°C and 22°C, temperatures near the optimum for growth of this species. Our aim was to study whether cardiac performance, especially the effect of adrenergic stimulation, differed when compared to salmonids. Sea bass and salmonids are both athletic swimmers but their cardiac anatomy differs markedly. The sea bass ventricle does not receive any oxygenated blood via a coronary circulation while salmonids have a well-developed arterial supply of oxygen to the compact layer of the ventricle. Using in situ perfused heart preparations, maximum cardiac performance of 18°C-acclimated sea bass (i.e. cardiac output=90.8± 6.6 ml min–1 kg–1 and power output=11.41±0.83 mW g–1) was found to be comparable to that previously reported for rainbow trout Oncorhynchus mykiss and brown trout Salmo trutta at similar temperatures and with tonic adrenergic (5 nmol l–1 adrenaline) stimulation. For 22°C-acclimated sea bass, heart rate was significantly higher, but maximum stroke volume was reduced by 22% (1.05±0.05 ml kg–1) compared with 18°C (1.38± 0.11 ml kg–1). As a result, maximum cardiac output (99.4±3.9 ml min–1 kg–1) was not significantly different at 22°C. Instead, maximum power output was 27% higher at 22°C (14.95±0.96 mW g–1) compared with 18°C, primarily because of the smaller relative ventricular mass in 22°C-acclimated sea bass. Compared with tonic adrenergic stimulation with 5 nmol l–1 adrenaline, maximum adrenergic stimulation of the sea bass heart produced only modest stimulatory effects at both temperatures (12–13% and 14–15% increases in maximum cardiac output and power output, respectively, with no chronotropic effect). Adrenergic stimulation also increased the cardiac sensitivity to filling pressure, with the maximum left-shift in the Starling curve being produced by 50–100 nmol l–1 adrenaline at 18°C and 10–50 nmol l–1 adrenaline at 22°C. We show that the sea bass, which lacks a coronary arterial oxygen supply to the ventricle, has a powerful heart. Its maximum performance is comparable to a salmonid heart, as is the modest stimulatory effect of adrenaline at high temperature.
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| 31. |
- Farrell, A. P., et al.
(author)
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Niche expansion of the shorthorn sculpin (Myoxocephalus scorpius) to Arctic waters is supported by a thermal independence of cardiac performance at low temperature
- 2013
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In: Canadian Journal of Zoology-Revue Canadienne De Zoologie. - : Canadian Science Publishing. - 0008-4301 .- 1480-3283. ; 91:8, s. 573-580
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Journal article (peer-reviewed)abstract
- Cardiovascular adaptations that permit successful exploitation of polar marine waters by fish requires a capacity to negate or compensate for the depressive effects of low temperatures on physiological processes. Here, we examined the effects of acute and chronic temperature change on the maximum cardiac performance of shorthorn sculpin (Myoxocephalus scorpius (L., 1758)) captured above the Arctic Circle. Our aim was to establish if the sculpin's success at low temperatures was achieved through thermal independence of cardiac function or via thermal compensation as a result of acclimation. Maximum cardiac performance was assessed at both 1 and 6 degrees C with a working perfused heart preparation that was obtained after fish had been acclimated to either 1 or 6 degrees C. Thus, tests were performed at the fish's acclimation temperature and with an acute temperature change. Maximum cardiac output, which was relatively large (> 50 mL.min(-1).kg(-1) body mass) for a benthic fish at a frigid temperature, was found to be independent of both acclimation temperature and test temperature. While maximum beta-adrenergic stimulation produced positive chronotropy at both acclimation temperatures, inotropic effects were weak or absent. We conclude that thermal independence of cardiac performance at low temperature likely facilitated the exploitation of polar waters by the shorthorn sculpin.
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| 32. |
- Farrell, William M., et al.
(author)
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The dust, atmosphere, and plasma at the moon
- 2024
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In: Reviews in Mineralogy and Geochemistry, Mineralogical Society of America. - : Walter de Gruyter. - 1529-6466 .- 1943-2666. ; 89, s. 563-609
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Journal article (peer-reviewed)
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| 33. |
- Franklin, C. E., et al.
(author)
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Thermal dependence of cardiac function in arctic fish: implications of a warming world
- 2013
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In: Journal of Experimental Biology. - : The Company of Biologists. - 0022-0949 .- 1477-9145. ; 216:22, s. 4251-4255
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Journal article (peer-reviewed)abstract
- With the Arctic experiencing one of the greatest and most rapid increases in sea temperatures in modern time, predicting how Arctic marine organisms will respond to elevated temperatures has become crucial for conservation biology. Here, we examined the thermal sensitivity of cardiorespiratory performance for three closely related species of sculpins that inhabit the Arctic waters, two of which, Gymnocanthus tricuspis and Myoxocephalus scorpioides, have adapted to a restricted range within the Arctic, whereas the third species, Myoxocephalus scorpius, has a wider distribution. We tested the hypothesis that the fish restricted to Arctic cold waters would show reduced cardiorespiratory scope in response to an increase in temperature, as compared with the more eurythermal M. scorpius. As expected from their biogeography, M. scorpioides and G. tricuspis maximised cardiorespiratory performance at temperatures between 1 and 4 degrees C, whereas M. scorpius maximised performance over a wider range of temperatures (1-10 degrees C). Furthermore, factorial scope for cardiac output collapsed at elevated temperature for the two high-latitude species, negatively impacting their ability to support aerobically driven metabolic processes. Consequently, these results concurred with our hypothesis, suggesting that the sculpin species restricted to the Arctic are likely to be negatively impacted by increases in ocean temperatures.
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| 34. |
- Fyfe, Ralph M., et al.
(author)
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The Holocene vegetation cover of Britain and Ireland : overcoming problems of scale and discerning patterns of openness
- 2013
-
In: Quaternary Science Reviews. - : Elsevier BV. - 0277-3791 .- 1873-457X. ; 73, s. 132-148
-
Journal article (peer-reviewed)abstract
- The vegetation of Europe has undergone substantial changes during the course of the Holocene epoch, resulting from range expansion of plants following climate amelioration, competition between taxa and disturbance through anthropogenic activities. Much of the detail of this pattern is understood from decades of pollen analytical work across Europe, and this understanding has been used to address questions relating to vegetation-climate feedback, biogeography and human impact. Recent advances in modelling the relationship between pollen and vegetation now make it possible to transform pollen proportions into estimates of vegetation cover at both regional and local spatial scales, using the Landscape Reconstruction Algorithm (LRA), i.e. the REVEALS (Regional Estimates of VEgetation Abundance from Large Sites) and the LOVE (Local VEgetation) models. This paper presents the compilation and analysis of 73 pollen stratigraphies from the British Isles, to assess the application of the LRA and describe the pattern of landscape/woodland openness (i.e. the cover of low herb and bushy vegetation) through the Holocene. The results show that multiple small sites can be used as an effective replacement for a single large site for the reconstruction of regional vegetation cover. The REVEALS vegetation estimates imply that the British Isles had a greater degree of landscape/woodland openness at the regional scale than areas on the European mainland. There is considerable spatial bias in the British Isles dataset towards wetland areas and uplands, which may explain higher estimates of landscape openness compared with Europe. Where multiple estimates of regional vegetation are available from within the same region inter-regional differences are greater than intra-regional differences, supporting the use of the REVEALS model to the estimation of regional vegetation from pollen data. (C) 2013 Elsevier Ltd. All rights reserved.
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| 35. |
- Greene, Chris, et al.
(author)
-
Microvascular stabilization via blood-brain barrier regulation prevents seizure activity
- 2022
-
In: Nature Communications. - : Springer Nature. - 2041-1723. ; 13
-
Journal article (peer-reviewed)abstract
- Blood-brain barrier (BBB) dysfunction is associated with worse epilepsy outcomes however the underlying molecular mechanisms of BBB dysfunction remain to be elucidated. Tight junction proteins are important regulators of BBB integrity and in particular, the tight junction protein claudin-5 is the most enriched in brain endothelial cells and regulates size-selectivity at the BBB. Additionally, disruption of claudin-5 expression has been implicated in numerous disorders including schizophrenia, depression and traumatic brain injury, yet its role in epilepsy has not been fully deciphered. Here we report that claudin-5 protein levels are significantly diminished in surgically resected brain tissue from patients with treatment-resistant epilepsy. Concomitantly, dynamic contrast-enhanced MRI in these patients showed widespread BBB disruption. We show that targeted disruption of claudin-5 in the hippocampus or genetic heterozygosity of claudin-5 in mice exacerbates kainic acid-induced seizures and BBB disruption. Additionally, inducible knockdown of claudin-5 in mice leads to spontaneous recurrent seizures, severe neuroinflammation, and mortality. Finally, we identify that RepSox, a regulator of claudin-5 expression, can prevent seizure activity in experimental epilepsy. Altogether, we propose that BBB stabilizing drugs could represent a new generation of agents to prevent seizure activity in epilepsy patients.
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| 36. |
- Hruska, Kimberly A., et al.
(author)
-
Influences of Sex and Activity Level on Physiological Changes in Individual Adult Sockeye Salmon during Rapid Senescence
- 2010
-
In: Physiological and Biochemical Zoology. - : University of Chicago Press. - 1522-2152 .- 1537-5293. ; 83:4, s. 663-676
-
Journal article (peer-reviewed)abstract
- A noninvasive biopsy protocol was used to sample plasma and gill tissue in individual sockeye salmon (Oncorhynchus nerka) during the critical life stage associated with spawning-arrival at a spawning channel through senescence to death several days later. Our main objective was to characterize the physiological changes associated with rapid senescence in terms of the physiological stress/cortisol hypersecretion model and the energy exhaustion model. Salmon lived an average of 5 d in the spawning channel, during which time there were three major physiological trends that were independent of sexual status: a large increase in plasma indicators of stress and exercise (i.e., lactate and cortisol), a decrease in the major plasma ions (i.e., Cl(-) and Na(+)) and osmolality, and a decrease in gross somatic energy reserves. Contrary to a generalized stress response, plasma glucose decreased in approximately 2/3 of the fish after arrival, as opposed to increasing. Furthermore, plasma cortisol levels at spawning-ground arrival were not correlated with the degree of ionoregulatory changes during rapid senescence. One mechanism of mortality in some fish may involve the exhaustion of energy reserves, resulting in the inability to mobilize plasma glucose. Sex had a significant modulating effect on the degree of physiological change. Females exhibited a greater magnitude of change for gross somatic energy, osmolality, and plasma concentrations of Cl(-), Na(+), cortisol, testosterone, 11-ketotestosterone, 17,20 beta-progesterone, and estradiol. The activity level of an individual on the spawning grounds appeared to influence the degree of some physiological changes during senescence. For example, males that received a greater frequency of attacks exhibited larger net decreases in plasma 11-ketotestosterone while on the spawning grounds. These results suggest that rapid senescence on spawning grounds is influenced by multiple physiological processes and perhaps behavior. This study provides some of the first data to look at sex differences in senescence in Pacific salmon.
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| 37. |
- Joyce, W., et al.
(author)
-
Adrenergic and adenosinergic regulation of the cardiovascular system in an Antarctic icefish: Insight into central and peripheral determinants of cardiac output
- 2019
-
In: Comparative Biochemistry and Physiology a-Molecular & Integrative Physiology. - : Elsevier BV. - 1095-6433. ; 230, s. 28-38
-
Journal article (peer-reviewed)abstract
- Icefishes characteristically lack the oxygen-binding protein haemoglobin and therefore are especially reliant on cardiovascular regulation to augment oxygen transport when oxygen demand increases, such as during activity and warming. Using both in vivo and in vitro experiments, we evaluated the roles for adrenaline and adenosine, two well-established cardio- and vasoactive molecules, in regulating the cardiovascular system of the blackfin icefish, Chaenocephalus aceratus. Despite increasing cardiac contractility (increasing twitch force and contraction kinetics in isometric myocardial strip preparations) and accelerating heart rate (f(H)), adrenaline (5 nmol kg(-1) bolus infra-arterial injection) did not significantly increase cardiac output ((Q) over dot) in vivo because it elicited a large decrease in vascular conductance (G(sys)). In contrast, and despite preliminary data suggesting a direct negative inotropic effect of adenosine on isolated atria and little effect on isolated ventricle strips, adenosine (500 nmol kg-1) generated a large increase in (Q) over dot by increasing G(sys), a change reminiscent of that previously reported during both acute warming and invoked activity. Our data thus illustrate how (Q) over dot in C. aceratus may be much more dependent on peripheral control of vasomotor tone than direct regulation of the heart.
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| 38. |
- Joyce, W., et al.
(author)
-
Exploring nature's natural knockouts: in vivo cardiorespiratory performance of Antarctic fishes during acute warming
- 2018
-
In: Journal of Experimental Biology. - : The Company of Biologists. - 0022-0949 .- 1477-9145. ; 221:15
-
Journal article (peer-reviewed)abstract
- We tested the hypothesis that blackfin icefish (Chaenocephalus aceratus), one of the six species in the family Channichthyidae (the icefishes) that do not express haemoglobin and myoglobin, lack regulatory cardiovascular flexibility during acute warming and activity. The experimental protocols were designed to optimize the surgical protocol and minimize stress. First, minimally invasive heart rate (f(H)) measurements were made during a thermal ramp until cardiac failure in C. aceratus and compared with those from the closely related red-blooded black rockcod (Notothenia coriiceps). Then, integrative cardiovascular adjustments were more extensively studied using flow probes and intravascular catheters in C. aceratus during acute warming (from 0 to 8 degrees C) at rest and after imposed activity. Chaenocephalus aceratus had a lower routine f H than N. coriiceps (9 beats min(-1) versus 14 beats min(-1)) and a lower peak f(H )during acute warming (38 beats min' versus 55 beats min(-1)) with a similar cardiac breakpoint temperature (13 and 14 degrees C, respectively). Routine cardiac output ((Q) over dot) for C. aceratus at similar to 0 degrees C was much lower (26.6 ml min(-1) kg(-1)) than previously reported, probably because fish in the present study had a low f(H) (12 beats min(-1)) indicative of a high routine vagal tone and low stress. Chaenocephalus aceratus increased oxygen consumption during acute warming and with activity. Correspondingly, (Q) over dot increased considerably (maximally 86.3 ml min(-1) kg(-1)), as did vascular conductance (5-fold). Thus, unlike earlier suggestions, these data provide convincing evidence that icefish can mount a well-developed cardiovascular regulation of heart rate, cardiac output and vascular conductance, and this regulatory capacity provides flexibility during acute warming.
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| 39. |
- Joyce, W., et al.
(author)
-
The effects of thermal acclimation on cardio-respiratory performance in an Antarctic fish (Notothenia coriiceps)
- 2018
-
In: Conservation Physiology. - : Oxford University Press (OUP). - 2051-1434. ; 6
-
Journal article (peer-reviewed)abstract
- The Southern Ocean has experienced stable, cold temperatures for over 10 million years, yet particular regions are currently undergoing rapid warming. To investigate the impacts of warming on cardiovascular oxygen transport, we compared the cardio-respiratory performance in an Antarctic notothenioid (Notothenia coriiceps) that was maintained at 0 or 5 degrees C for 6.0-9.5 weeks. When compared at the fish's respective acclimation temperature, the oxygen consumption rate and cardiac output were significantly higher in 5 degrees C-acclimated than 0 degrees C-acclimated fish. The 2.7-fold elevation in cardiac output in 5 degrees C-acclimated fish (17.4 vs. 6.5 ml min(-1) kg(-1)) was predominantly due to a doubling of stroke volume, likely in response to increased cardiac preload, as measured by higher central venous pressure (0.15 vs. 0.08 kPa); tachycardia was minor (295 vs. 25.2 beats min(-1)). When fish were acutely warmed, oxygen consumption rate increased by similar amounts in 0 degrees C- and 5 degrees C-acclimated fish at equivalent test temperatures. In both acclimation groups, the increases in oxygen consumption rate during acute heating were supported by increased cardiac output achieved by elevating heart rate, while stroke volume changed relatively little. Cardiac output was similar between both acclimation groups until 12 degrees C when cardiac output became significantly higher in 5 degrees C-acclimated fish, driven largely by their higher stroke volume. Although cardiac arrhythmias developed at a similar temperature (similar to 14.5 degrees C) in both acclimation groups, the hearts of 5 degrees C-acclimated fish continued to pump until significantly higher temperatures (CTmax for cardiac function 17.7 vs. 15.0 degrees C for 0 degrees C-acclimated fish). These results demonstrate that N. coriiceps is capable of increasing routine cardiac output during both acute and chronic warming, although the mechanisms are different (heart rate-dependent versus primarily stroke volume-dependent regulation, respectively). Cardiac performance was enhanced at higher temperatures following 5 degrees C acclimation, suggesting cardiovascular function may not constrain the capacity of N. coriiceps to withstand a warming climate.
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| 40. |
- Kehoe, Laura, et al.
(author)
-
Inclusion, Transparency, and Enforcement: How the EU-Mercosur Trade Agreement Fails the Sustainability Test Comment
- 2020
-
In: One Earth. - : Elsevier BV. - 2590-3322 .- 2590-3330. ; 3:3, s. 268-272
-
Journal article (peer-reviewed)abstract
- Trade agreements could help to protect human rights, critical ecosystems, and the climate-but only if sustainability becomes a cornerstone of international trade. The EU-Mercosur trade agreement fails to meet our three tenets of sustainable trade agreements: (1) inclusion of local communities, (2) transparency mechanisms to trace commodities and provide open-access information, and (3) enforcement to legally uphold sustainability commitments.
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| 41. |
- Mehaffy, Michael W., et al.
(author)
-
Correction to : Implementing the New Urban Agenda: the central role of public space (URBAN DESIGN International, (2019), 24, 1, (4-6), 10.1057/s41289-018-0063-2)
- 2019
-
In: Urban Design International. - : Palgrave Macmillan Ltd.. - 1357-5317 .- 1468-4519. ; 24:1
-
Journal article (peer-reviewed)abstract
- In the second paragraph in the second column on page 2 beginning “1. How important are public spaces as engines of human well-being, economic development and social justice, and what are the threats to them, especially from private interests?” the following sentence has been removed: “Setha Low also points to a worrisome diminution of the capacity of public spaces to promote social justice and diversity, replaced by a “politics of exclusion”.” On page 3 of the final sentence of the first paragraph “Ali Madanipour and Setha Low again warn of the danger of unequal access when private sector actors have increasing control over public spaces” has been replaced by “Ali Madanipour again warns of the danger of unequal access when private sector actors have increasing control over public spaces”.
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| 42. |
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| 43. |
- O'Brien, K. M., et al.
(author)
-
Resilience of cardiac performance in Antarctic notothenioid fishes in a warming climate
- 2021
-
In: Journal of Experimental Biology. - : The Company of Biologists. - 0022-0949 .- 1477-9145. ; 224:10
-
Journal article (peer-reviewed)abstract
- Warming in the region of the Western Antarctic Peninsula is occurring at an unprecedented rate, which may threaten the survival of Antarctic notothenioid fishes. Herein, we review studies characterizing thermal tolerance and cardiac performance in notothenioids - a group that includes both red-blooded species and the white-blooded, haemoglobinless icefishes - as well as the relevant biochemistry associated with cardiac failure during an acute temperature ramp. Because icefishes do not feed in captivity, making long-term acclimation studies unfeasible, we focus only on the responses of red-blooded notothenioids to warm acclimation. With acute warming, hearts of the white-blooded icefish Chaenocephalus aceratus display persistent arrhythmia at a lower temperature (8 degrees C) compared with those of the red-blooded Notothenia coriiceps (14 degrees C). When compared with the icefish, the enhanced cardiac performance of N. coriiceps during warming is associated with greater aerobic capacity, higher ATP levels, less oxidative damage and enhanced membrane integrity. Cardiac performance can be improved in N. coriiceps with warm acclimation to 5 degrees C for 6-9 weeks, accompanied by an increase in the temperature at which cardiac failure occurs. Also, both cardiac mitochondrial and microsomal membranes are remodelled in response to warm acclimation in N. coriiceps, displaying homeoviscous adaptation. Overall, cardiac performance in N. coriiceps is malleable and resilient to warming, yet thermal tolerance and plasticity vary among different species of notothenioid fishes; disruptions to the Antarctic ecosystem driven by climate warming and other anthropogenic activities endanger the survival of notothenioids, warranting greater protection afforded by an expansion of marine protected areas.
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| 44. |
- Sandblom, Erik, 1978, et al.
(author)
-
Cardiac preload and venous return in swimming sea bass (Dicentrarchus labrax L.)
- 2005
-
In: Journal of Experimental Biology. - : The Company of Biologists. - 0022-0949 .- 1477-9145. ; 208:10, s. 1927-1935
-
Journal article (peer-reviewed)abstract
- Cardiac preload (central venous; pressure, Pcv), mean circulatory filling pressure (MCFP), dorsal aortic blood pressure (P-DA) and relative cardiac output (Q) were measured in sea bass (Dicentrarchus labrax) at rest and while swimming at 1 and 2 BL s(-1). MCFP, an index of venous capacitance and the upstream venous pressure driving the return of venous blood to the heart, was measured as the plateau in Pcv during ventral aortic occlusion. Compared with resting values, swimming at 1 and 2BL s(-1) increased Q (by 15 +/- 1.5 and 38 +/- 6.5%, respectively), Pcv (from 0.11 +/- 0.01 kPa to 0.12 +/- 0.01 and 0.16 +/- 0.02 kPa, respectively), MCFP (from 0.27 +/- 0.02 kPa to 0.31 +/- 0.02 and 0.40 +/- 0.04 kPa, respectively) and the calculated pressure gradient for venous return (Delta Pv, from 0.16 +/- 0.01 kPa to 0.18 +/- 0.02 and 0.24 +/- 0.02 kPa, respectively), but not PDA. In spite of an increased preload, the increase in 0 was exclusively mediated by an increased heart rate (fH, from 80 +/- 4 beats min(-1) to 88 +/- 4 and 103 +/- 3 beats min(-1), respectively), and stroke volume (V-s) remained unchanged. Prazosin treatment (1 mg kg(-1) M-b) abolished pressure and flow changes during swimming at 1 BL s(-1), but not 2 BL s(-1), indicating that other control systems besides an alpha-adrenoceptor control are involved. This study is the first to address the control of venous capacitance in swimming fish. It questions the generality that increased Q during swimming is regulated primarily through V-s and shows that an increased cardiac filling pressure does not necessarily lead to an increased V-s in fish, but may instead compensate for a reduced cardiac filling time.
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| 45. |
- Sandblom, Erik, 1978, et al.
(author)
-
Central venous pressure and mean circulatory filling pressure in the dogfish Squalus acanthias: adrenergic control and role of the pericardium
- 2006
-
In: American Journal of Physiology-Regulatory Integrative and Comparative Physiology. - : American Physiological Society. - 0363-6119 .- 1522-1490. ; 291:5
-
Journal article (peer-reviewed)abstract
- Central venous pressure and mean circulatory filling pressure in the dogfish Squalus acanthias: adrenergic control and role of the pericardium. Am J Physiol Regul Integr Comp Physiol 291: R1465-R1473, 2006. First published July 6, 2006; doi: 10.1152/ajpregu.00282.2006.-Subambient central venous pressure (P-ven) and modulation of venous return through cardiac suction (vis a fronte) characterizes the venous circulation in sharks. Venous capacitance was estimated in the dogfish Squalus acanthias by measuring the mean circulatory filling pressure (MCFP) during transient occlusion of cardiac outflow. We tested the hypothesis that venous return and cardiac preload can be altered additionally through adrenergic changes of venous capacitance. The experiments involved the surgical opening of the pericardium to place a perivascular occluder around the conus arteriosus. Another control group was identically instrumented, but lacked the occluder, and was subjected to the same pharmacological protocol to evaluate how pericardioectomy affected cardiovascular status. Routine P-ven was negative (-0.08 +/- 0.02 kPa) in control fish but positive (0.09 +/- 0.01 kPa) in the pericardioectomized group. Injections of 5 mu g/kg body mass (M-b) of epinephrine and phenylephrine (100 mu g/kg M-b) increased P-ven and MCFP, whereas isoproterenol (1 mu g/kg M-b) decreased both variables. Thus, constriction and relaxation of the venous vasculature were mediated through the respective stimulation of alpha- and beta-adrenergic receptors. alpha-Adrenergic blockade with prazosin (1 mg/kg M-b) attenuated the responses to phenylephrine and decreased resting Pven in pericardioectomized animals. Our results provide convincing evidence for adrenergic control of the venous vasculature in elasmobranchs, although the pericardium is clearly an important component in the modulation of venous function. Thus active changes in venous capacitance have previously been underestimated as an important means of modulating venous return and cardiac performance in this group.
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| 46. |
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| 47. |
- Storch, Eric A., et al.
(author)
-
Little Doubt That CBT Works for Pediatric OCD
- 2020
-
In: Journal of the American Academy of Child and Adolescent Psychiatry. - : Elsevier BV. - 0890-8567. ; 59:7, s. 785-787
-
Journal article (peer-reviewed)abstract
- We write with great concern in response to the recent systematic review and meta-analysis of cognitive-behavioral therapy (CBT) in pediatric obsessive-compulsive disorder (OCD) by Uhre et al.1 Although the authors’ results consistently support the clinical efficacy of CBT for pediatric OCD, we expect that, much like ourselves, readers will be confused by the discordant and inappropriate conclusions that they put forward. These conclusions stem from the authors’ application and interpretation of their particular qualitative methods, which could lead important stakeholders (eg, parents, patients, clinicians, and payers) to wrongly discount clear evidence for what is known to be the best evidence-based therapy for pediatric OCD.
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| 48. |
- Aad, G., et al.
(author)
-
- 2015
-
In: Physical Review C (Nuclear Physics). - 0556-2813 .- 1089-490X. ; 92:3
-
Journal article (peer-reviewed)
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| 49. |
- Aad, G., et al.
(author)
-
- 2015
-
In: The European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6052. ; 75:7
-
Journal article (peer-reviewed)
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| 50. |
- Aad, G., et al.
(author)
-
- 2015
-
In: The European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6052. ; 75:7
-
Journal article (peer-reviewed)
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