| 1. |
- Ghaemi, M., et al.
(author)
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Growth of Nb films on Cu for superconducting radio frequency cavities by direct current and high power impulse magnetron sputtering: A molecular dynamics and experimental study
- 2024
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In: Surface & Coatings Technology. - : Elsevier BV. - 0257-8972 .- 1879-3347. ; 476
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Journal article (peer-reviewed)abstract
- The use of superconducting radio frequency (rf) cavities in particle accelerators necessitates that copper (Cu) surfaces are coated by thin niobium (Nb) films, predominantly synthesized by magnetron sputtering. A key feature of the rf cavities is that they exhibit a complex three-dimensional geometry, such that during Nb film growth vapor is not deposited on a flat substrate. The latter, combined with the line-of-sight nature of the deposition flux in conventional magnetron sputtering methods (including direct current magnetron sputtering; DCMS) yields films with porous columnar morphologies on surfaces of the cavities that do not face the magnetron source. High-power impulse magnetron sputtering (HiPIMS) is a variant of sputtering that generates highly-ionized fluxes. Using electrical fields, such fluxes can be deflected to trajectories that are closer to the substrate normal and, thereby, dense and uniform layers can be deposited on all surfaces of the rf cavities. In the present work, we use classical molecular dynamics simulations to model Nb film growth on Cu substrates at conditions consistent with those prevailing during DCMS and HiPIMS. Our computational results are in qualitative agreement with experimental data (also generated in the present study), with respect to film morphology. Based on this agreement and by studying the evolution of the simulated systems, we suggest that the morphology of HiPIMS-grown films (as compared to their DCMS counterparts) is the result of the combined effects of deflection of ionized sputtered particles to trajectories parallel to the substrate normal, bombardment-induced interruption of crystal growth, and ballistic atomic rearrangement along with dynamic thermal annealing caused by energetic film-forming species. Moreover, the predictions of our model with respect to dynamic processes at the film-substrate interface and their effect on local epitaxial growth are discussed.
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| 2. |
- Baradaran-Heravi, A., et al.
(author)
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Three novel CYP21A2 mutations and their protein modelling in patients with classical 21-hydroxylase deficiency from northeastern Iran
- 2007
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In: Clinical Endocrinology. - : Wiley. - 0300-0664 .- 1365-2265. ; 67:3, s. 335-341
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Journal article (peer-reviewed)abstract
- Objective: Congenital adrenal hyperplasia (CAH) refers to a group of autosomal recessive disorders frequently caused by mutations in the steroid 21-hydroxylase gene (CYP21A2). We describe three novel CYP21A2 mutations in CAH patients. Design and methods: Sequence analysis of the entire CYP21A2 gene followed by molecular modelling was performed in three unrelated classical CAH patients of northeastern Iranian origin. The active (CYP21A2) and pseudogene (CYP21A1P) alleles were screened for the presence of the new variations in controls. Results: Two novel missense mutations, F404S in exon 9 and T450P in exon 10, were found in homozygous forms in two female patients with a salt-wasting (SW) phenotype. These novel variants were screened by allele-specific polymerase chain reaction (PCR) and excluded in 100 unrelated normal alleles. Prediction of clinical severity, based on molecular modelling and sequence conservation, correlates well with the clinical diagnosis of the patients carrying these mutations. The third novel mutation, a small 10-bp deletion in exon 1, g.19_28del, was found in a female patient with a simple virilizing phenotype in a compound heterozygous form with the common intron 2 splice mutation (IVS2-13A/C>G). This frameshift mutation causes a premature stop codon at amino acid position 48, L48X, resulting in a nonfunctional protein. The CYP21A1P pseudogene alleles were also screened and none of these novel mutations could be detected. Conclusions: Three novel mutations were found in the CYP21A2 gene and predicted to drastically impair enzyme activity resulting in severe classic CAH. None of these mutations occurs in the CYP21A1P pseudogene. © 2007 The Authors.
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| 3. |
- Ghaemi, Hirad, 1980, et al.
(author)
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CLEAN technique in strip-map SAR for high-quality imaging
- 2009
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In: IEEE Aerospace Conference Proceedings. - 1095-323X. - 9781424426225 ; , s. Art. no. 4839474-
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Conference paper (peer-reviewed)abstract
- The maximum obtainable resolution of a strip-map synthetic aperture radar (SAR) system can be retained by simply avoiding weighting, or tapering, data samples in the along-track compression process. However, this will lead to hazardous artifacts caused by strong sidelobes of the corresponding adjacent scatterers whose interference might severely weaken the desired targets or even introduce false targets. On the other hand, some residual artifacts, even after tapering process, may still deteriorate the quality (contrast) of the SAR image. These issues can be remedied by applying the so-called CLEAN technique, which can mitigate these ill-effects in strip-map SAR imagery while maintaining the maximum resolution. This, indeed, is carried out as a post processing step, i.e., after the azimuth compression is accomplished, in the SAR system. The objective of this paper is to extend the CLEAN technique to strip-map SAR system to produce high-quality images with a very good along-track resolution. The algorithm is then applied to data from a ground-based circular SAR (CSAR) system to verify its implementation as well as this new application of the CLEAN technique.
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| 4. |
- Ghaemi, Hirad, 1980, et al.
(author)
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RELAX-based autofocus algorithm for high-resolution strip-map SAR
- 2009
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In: IEEE National Radar Conference - Proceedings. - 1097-5659. - 9781424428717 ; , s. 1 - 6
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Conference paper (peer-reviewed)abstract
- This paper addresses the non-iterative quality phase gradient autofocus (QPGA) technique which was originally proposed to remove one-dimensional phase errors in spotlight-mode synthetic aperture radar (SAR) imagery. By enriching the source pool, the method is modified in a way suitable for autofocus in stripmap-mode SAR system with the advantage of being independent of any priori assumptions. Unlike the QPGA the potential candidates, i.e., dominant scatterers located along azimuth in each specific range bin, are automatically selected by exploiting the one-dimensional RELAX algorithm. Furthermore, RELAX is capable of estimating the size of blur window which is, in fact, associated with the Doppler spread of signal spectrum. The corresponding model includes four parameters i.e., complex amplitude, delay, Doppler center and spectral width. The proposed method has been applied to data extracted by a ground-based rotating coherent Doppler radar operating in strip-mapping mode SAR, with the aim of high-resolution clutter detection.
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| 5. |
- Ghaemi, Z., et al.
(author)
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LaSVM-based big data learning system for dynamic prediction of air pollution in Tehran
- 2018
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In: Environmental Monitoring and Assessment. - : Springer Science and Business Media LLC. - 0167-6369 .- 1573-2959. ; 190:5
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Journal article (peer-reviewed)abstract
- Due to critical impacts of air pollution, prediction and monitoring of air quality in urban areas are important tasks. However, because of the dynamic nature and high spatio-temporal variability, prediction of the air pollutant concentrations is a complex spatio-temporal problem. Distribution of pollutant concentration is influenced by various factors such as the historical pollution data and weather conditions. Conventional methods such as the support vector machine (SVM) or artificial neural networks (ANN) show some deficiencies when huge amount of streaming data have to be analyzed for urban air pollution prediction. In order to overcome the limitations of the conventional methods and improve the performance of urban air pollution prediction in Tehran, a spatio-temporal system is designed using a LaSVM-based online algorithm. Pollutant concentration and meteorological data along with geographical parameters are continually fed to the developed online forecasting system. Performance of the system is evaluated by comparing the prediction results of the Air Quality Index (AQI) with those of a traditional SVM algorithm. Results show an outstanding increase of speed by the online algorithm while preserving the accuracy of the SVM classifier. Comparison of the hourly predictions for next coming 24 h, with those of the measured pollution data in Tehran pollution monitoring stations shows an overall accuracy of 0.71, root mean square error of 0.54 and coefficient of determination of 0.81. These results are indicators of the practical usefulness of the online algorithm for real-time spatial and temporal prediction of the urban air quality.
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| 6. |
- Lopez-Cazalilla, A., et al.
(author)
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Effect of surface orientation on blistering of copper under high fluence keV hydrogen ion irradiation
- 2024
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In: Acta Materialia. - : Elsevier BV. - 1359-6454 .- 1873-2453. ; 266
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Journal article (peer-reviewed)abstract
- Copper and hydrogen are among the most common elements that are widely used in industrial and fundamental research applications. Copper surfaces are often exposed to hydrogen in the form of charged ions. The hydrogen ions can accelerate towards the surface, resulting in an accumulation of hydrogen below the surface. Harmless in low concentrations, prolonged hydrogen exposure can lead to dramatic changes on copper surfaces. This effect is visible to the naked eye in the form of blisters densely covering the exposed surface. Blisters are structural modifications that can affect the physical properties of the surface including, for example, vacuum dielectric strength. Using scanning electron microscopy we found that the blistering of the irradiated polycrystalline copper surface does not grow uniformly with ion fluence. Initially, only some grains exhibit blisters, while others remain intact. Our experiments indicate that grains with the {100} orientation are the most prone to blistering, while the grains oriented in the {110} are the most resistant to it. Moreover, we noticed that blisters assume different shapes correlating with specific grain orientation. Good agreement of experiments with the atomistic simulations explains the difference in the shapes of the blisters by specific behavior of dislocations within the FCC crystal structure. Moreover, our simulations reveal the correlation of the delay in blister formation on surfaces with certain orientations compared to the others with the dependence of the hydrogen penetration depth and the depth and amount of vacancies in copper on the orientation of the irradiated surface.
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| 7. |
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