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1.
  • Béthermin, Matthieu, et al. (author)
  • The ALMA-ALPINE [CII] survey: Kennicutt-Schmidt relation in four massive main-sequence galaxies at z ~ 4.5
  • 2023
  • In: Astronomy and Astrophysics. - 0004-6361 .- 1432-0746. ; 680
  • Journal article (peer-reviewed)abstract
    • Aims. The Kennicutt-Schmidt (KS) relation between the gas and the star formation rate (SFR) surface density (Σgas - ΣSFR) is essential to understand star formation processes in galaxies. To date, it has been measured up to z ~ 2.5 in main-sequence galaxies. In this Letter our aim is to put constraints at z ~ 4.5 using a sample of four massive main-sequence galaxies observed by ALMA at high resolution. Methods. We obtained ~0.3″-resolution [CII] and continuum maps of our objects, which we then converted into gas and obscured SFR surface density maps. In addition, we produced unobscured SFR surface density maps by convolving Hubble ancillary data in the rest-frame UV. We then derived the average ΣSFR in various Σgas bins, and estimated the uncertainties using a Monte Carlo sampling. Results. Our galaxy sample follows the KS relation measured in main-sequence galaxies at lower redshift, and is slightly lower than the predictions from simulations. Our data points probe the high end both in terms of Σgas and ΣSFR, and gas depletion timescales (285-843 Myr) remain similar to z ~ 2 objects. However, three of our objects are clearly morphologically disturbed, and we could have expected shorter gas depletion timescales (≲100 Myr) similar to merger-driven starbursts at lower redshifts. This suggests that the mechanisms triggering starbursts at high redshift may be different than in the low- and intermediate-z Universe.
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2.
  • Grazian, A., et al. (author)
  • Lyman continuum escape fraction of faint galaxies at z similar to 3.3 in the CANDELS/GOODS-North, EGS, and COSMOS fields with LBC
  • 2017
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 602
  • Journal article (peer-reviewed)abstract
    • Context. The reionization of the Universe is one of the most important topics of present-day astrophysical research. The most plausible candidates for the reionization process are star-forming galaxies, which according to the predictions of the majority of the theoretical and semi-analytical models should dominate the H I ionizing background at z greater than or similar to 3. Aims. We measure the Lyman continuum escape fraction, which is one of the key parameters used to compute the contribution of star-forming galaxies to the UV background. It provides the ratio between the photons produced at lambda <= 912 angstrom rest-frame and those that are able to reach the inter-galactic medium, i.e. that are not absorbed by the neutral hydrogen or by the dust of the galaxy's inter-stellar medium. Methods. We used ultra-deep U-band imaging (U = 30.2 mag at 1 sigma) from Large Binocular Camera at the Large Binocular Telescope (LBC/LBT) in the CANDELS/GOODS-North field and deep imaging in the COSMOS and EGS fields in order to estimate the Lyman continuum escape fraction of 69 star-forming galaxies with secure spectroscopic redshifts at 3.27 <= z <= 3.40 to faint magnitude limits (L = 0.2L*, or equivalently M-1500 similar to -19). The narrow redshift range implies that the LBC U-band filter exclusively samples the lambda <= 912 angstrom rest-frame wavelengths. Results. We measured through stacks a stringent upper limit (<1.7% at 1 sigma) for the relative escape fraction of H I ionizing photons from bright galaxies (L > L*), while for the faint population (L = 0.2L*) the limit to the escape fraction is less than or similar to 10%. We computed the contribution of star-forming galaxies to the observed UV background at z similar to 3 and find that it is not sufficient to keep the Universe ionized at these redshifts unless their escape fraction increases significantly (>= 10%) at low luminosities (M-1500 >= -19). Conclusions. We compare our results on the Lyman continuum escape fraction of high-z galaxies with recent estimates in the literature, and discuss future prospects to shed light on the end of the Dark Ages. In the future, strong gravitational lensing will be fundamental in order to measure the Lyman continuum escape fraction down to faint magnitudes (M-1500 similar to -16) that are inaccessible with the present instrumentation on blank fields. These results will be important in order to quantify the role of faint galaxies to the reionization budget.
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3.
  • Mobasher, B., et al. (author)
  • Photometric redshifts of galaxies in COSMOS
  • 2007
  • In: Astrophysical Journal Supplement Series. - : American Astronomical Society. - 0067-0049 .- 1538-4365. ; 172:1, s. 117-131
  • Journal article (peer-reviewed)abstract
    • We present photometric redshifts for the COSMOS survey derived from a new code, optimized to yield accurate and reliable redshifts and spectral types of galaxies down to faint magnitudes and redshifts out to z similar to 1.2. The technique uses chi (2) template fitting, combined with luminosity function priors and with the option to estimate the internal extinction [ or E( B-V)]. The median most probable redshift, best-fit spectral type and reddening, absolute magnitude, and stellarmass are derived in addition to the full redshift probability distributions. Using simulations with sampling and noise similar to those in COSMOS, the accuracy and reliability is estimated for the photometric redshifts as a function of the magnitude limits of the sample, S/N ratios, and the number of bands used. We find from the simulations that the ratio of derived 95% confidence interval in the chi (2) probability distribution to the estimated photometric redshift (D-95) can be used to identify and exclude the catastrophic failures in the photometric redshift estimates. To evaluate the reliability of the photometric redshifts, we compare the derived redshifts with high-reliability spectroscopic redshifts for a sample of 868 normal galaxies with z < 1: 2 from zCOSMOS. Considering different scenarios, depending on using prior, no prior, and/or extinction, we compare the photometric and spectroscopic redshifts for this sample. The rms scatter between the estimated photometric redshifts and known spectroscopic redshifts is sigma(Delta( z))= 0. 031, where Delta(z) ( z(phot) - z(spec))/( 1+ z(spec)) with a small fraction of outliers (< 2.5%) [ outliers are defined as objects with Delta( z) > 3 sigma(Delta( z)), where sigma(Delta(z)) is the rms scatter in Delta( z)]. We also find good agreement [sigma(Delta(z))= 0.10] between photometric and spectroscopic redshifts for type II AGNs. We compare results fromour photometric redshift procedure with three other independent codes and find them in excellent agreement. We show preliminary results, based on photometric redshifts for the entire COSMOS sample ( to i < 25 mag).
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4.
  • Amorín, R. O., et al. (author)
  • Ubiquitous broad-line emission and the relation between ionized gas outflows and Lyman continuum escape in Green Pea galaxies
  • 2024
  • In: Astronomy and Astrophysics. - 0004-6361 .- 1432-0746. ; 682
  • Journal article (peer-reviewed)abstract
    • We report observational evidence of highly turbulent ionized gas kinematics in a sample of 20 Lyman continuum (LyC) emitters (LCEs) at low redshift (z ∼ 0.3). Detailed Gaussian modeling of optical emission line profiles in high-dispersion spectra consistently shows that both bright recombination and collisionally excited lines can be fitted as one or two narrow components with intrinsic velocity dispersion of σ ∼ 40 − 100 km s−1, in addition to a broader component with σ ∼ 100 − 300 km s−1, which contributes up to ∼40% of the total flux and is preferentially blueshifted from the systemic velocity. We interpret the narrow emission as highly ionized gas close to the young massive star clusters and the broader emission as a signpost of unresolved ionized outflows, resulting from massive stars and supernova feedback. We find a significant correlation between the width of the broad emission and the LyC escape fraction, with strong LCEs exhibiting more complex and broader line profiles than galaxies with weaker or undetected LyC emission. We provide new observational evidence supporting predictions from models and simulations; our findings suggest that gas turbulence and outflows resulting from strong radiative and mechanical feedback play a key role in clearing channels through which LyC photons escape from galaxies. We propose that the detection of blueshifted broad emission in the nebular lines of compact extreme emission-line galaxies can provide a new indirect diagnostic of Lyman photon escape, which could be useful to identify potential LyC leakers in the epoch of reionization with the JWST.
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5.
  • Chisholm, J., et al. (author)
  • The far-ultraviolet continuum slope as a Lyman Continuum escape estimator at high redshift
  • 2022
  • In: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 517:4, s. 5104-5120
  • Journal article (peer-reviewed)abstract
    • Most of the hydrogen in the intergalactic medium (IGM) was rapidly ionized at high redshifts. While observations have established that reionization occurred, observational constraints on the high-redshift ionizing emissivity remain elusive. Here, we present a new analysis of the Low-redshift Lyman Continuum Survey (LzLCS) and literature observations, a combined sample of 89 star-forming galaxies at redshifts near 0.3 with Hubble Space Telescope observations of their ionizing continua (or Lyman Continuum, LyC). We find a strong (6σ significant) inverse correlation between the continuum slope at 1550 Å (defined as Fλ ∝ λβ1550obs⁠) and both the LyC escape fraction (fesc, LyC) and fesc, LyC times the ionizing photon production efficiency (ξion). On average, galaxies with redder continuum slopes have smaller fesc, LyC than galaxies with bluer slopes mainly due to higher dust attenuation. More than 5 per cent (20 per cent) of the LyC emission escapes galaxies with β1550obs <−2.1 (−2.6). We find strong correlations between β1550obs and the [O III]/[O II] flux ratio (at 7.5σ significance), galaxy stellar mass (at 5.9σ), the gas-phase metallicity (at 4.6σ), and the observed far-ultraviolet absolute magnitude (at 3.4σ). Using previous observations of β1550obs at high redshift, we estimate the evolution of fesc, LyC with both redshift and galaxy magnitude. The LzLCS observations suggest that fainter and lower mass galaxies dominate the ionizing photon budget at higher redshift, possibly due to their rapidly evolving metal and dust content. Finally, we use our correlation between β1550obs and fesc, LyC × ξion to predict the ionizing emissivity of galaxies during the epoch of reionization. Our estimated emissivities match IGM observations, and suggest that star-forming galaxies emit sufficient LyC photons into the IGM to exceed recombinations near redshifts of 7–8.
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6.
  • Marques-Chaves, R., et al. (author)
  • No correlation of the Lyman continuum escape fraction with spectral hardness
  • 2022
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 663
  • Journal article (peer-reviewed)abstract
    • The properties that govern the production and escape of hydrogen-ionizing photons (Lyman continuum, LyC; with energies > 13.6 eV) in star-forming galaxies are still poorly understood, but they are key to identifying and characterizing the sources that reionized the Universe. Here we empirically explore the relation between the hardness of ionizing radiation and the LyC leakage in a large sample of low-z star-forming galaxies from the recent Hubble Space Telescope Low-z Lyman Continuum Survey. Using Sloan Digital Sky Survey stacks and deep X-shooter observations, we investigate the hardness of the ionizing spectra (QHe+/QH) between 54.4 eV (He+) and 13.6 eV (H) from the optical recombination lines He II 4686 Å and Hβ 4861 Å for galaxies with LyC escape fractions spanning a wide range, fesc(LyC) ≃ 0−90%. We find that the observed intensity of He II/Hβ is primarily driven by variations in the metallicity, but is not correlated with LyC leakage. Both very strong (esc(LyC)> ≃ 0.5) and nonleakers (esc(LyC)> ≃ 0) present similar observed intensities of He II and Hβ at comparable metallicity, between ≃0.01 and ≃0.02 for 12 + log(O/H)> 8.0 and < 8.0, respectively. Our results demonstrate that QHe+/QH does not correlate with fesc(LyC), which implies that strong LyC emitters do not show harder ionizing spectra than nonleakers at similar metallicity.
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7.
  • Bonekamp, N. A., et al. (author)
  • Small-molecule inhibitors of human mitochondrial DNA transcription
  • 2020
  • In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 588, s. 712-716
  • Journal article (peer-reviewed)abstract
    • Altered expression of mitochondrial DNA (mtDNA) occurs in ageing and a range of human pathologies (for example, inborn errors of metabolism, neurodegeneration and cancer). Here we describe first-in-class specific inhibitors of mitochondrial transcription (IMTs) that target the human mitochondrial RNA polymerase (POLRMT), which is essential for biogenesis of the oxidative phosphorylation (OXPHOS) system(1-6). The IMTs efficiently impair mtDNA transcription in a reconstituted recombinant system and cause a dose-dependent inhibition of mtDNA expression and OXPHOS in cell lines. To verify the cellular target, we performed exome sequencing of mutagenized cells and identified a cluster of amino acid substitutions in POLRMT that cause resistance to IMTs. We obtained a cryo-electron microscopy (cryo-EM) structure of POLRMT bound to an IMT, which further defined the allosteric binding site near the active centre cleft of POLRMT. The growth of cancer cells and the persistence of therapy-resistant cancer stem cells has previously been reported to depend on OXPHOS7-17, and we therefore investigated whether IMTs have anti-tumour effects. Four weeks of oral treatment with an IMT is well-tolerated in mice and does not cause OXPHOS dysfunction or toxicity in normal tissues, despite inducing a strong anti-tumour response in xenografts of human cancer cells. In summary, IMTs provide a potent and specific chemical biology tool to study the role of mtDNA expression in physiology and disease. Inhibitors of mitochondrial transcription that target human mitochondrial RNA polymerase provide a chemical biology tool for studying the role of mitochondrial DNA expression in a wide range of pathologies.
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9.
  • Flury, Sophia R., et al. (author)
  • The Low-redshift Lyman Continuum Survey. I. New, Diverse Local Lyman Continuum Emitters
  • 2022
  • In: Astrophysical Journal Supplement Series. - : American Astronomical Society. - 0067-0049 .- 1538-4365. ; 260:1
  • Journal article (peer-reviewed)abstract
    • The origins of Lyman continuum (LyC) photons responsible for the reionization of the universe are as of yet unknown and highly contested. Detecting LyC photons from the Epoch of Reionization is not possible due to absorption by the intergalactic medium, which has prompted the development of several indirect diagnostics to infer the rate at which galaxies contribute LyC photons to reionize the universe by studying lower-redshift analogs. We present the Low-redshift Lyman Continuum Survey (LzLCS) comprising measurements made with the Hubble Space Telescope Cosmic Origins Spectrograph for a z = 0.2-0.4 sample of 66 galaxies. After careful processing of the far-UV spectra, we obtain a total of 35 Lyman continuum emitters (LCEs) detected with 97.725% confidence, nearly tripling the number of known local LCEs. We estimate escape fractions from the detected LyC flux and upper limits on the undetected LyC flux, finding a range of LyC escape fractions up to 50%. Of the 35 LzLCS LCEs, 12 have LyC escape fractions greater than 5%, more than doubling the number of known local LCEs with cosmologically relevant LyC escape.
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10.
  • Flury, Sophia R., et al. (author)
  • The Low-redshift Lyman Continuum Survey. II. New Insights into LyC Diagnostics
  • 2022
  • In: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 930:2
  • Journal article (peer-reviewed)abstract
    • The Lyman continuum (LyC) cannot be observed at the epoch of reionization (z greater than or similar to 6) owing to intergalactic H i absorption. To identify LyC emitters (LCEs) and infer the fraction of escaping LyC, astronomers have developed various indirect diagnostics of LyC escape. Using measurements of the LyC from the Low-redshift Lyman Continuum Survey (LzLCS), we present the first statistical test of these diagnostics. While optical depth indicators based on Ly alpha, such as peak velocity separation and equivalent width, perform well, we also find that other diagnostics, such as the [O iii]/[O ii] flux ratio and star formation rate surface density, predict whether a galaxy is an LCE. The relationship between these galaxy properties and the fraction of escaping LyC flux suggests that LyC escape depends strongly on H i column density, ionization parameter, and stellar feedback. We find that LCEs occupy a range of stellar masses, metallicities, star formation histories, and ionization parameters, which may indicate episodic and/or different physical causes of LyC escape.
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13.
  • Saldana-Lopez, Alberto, et al. (author)
  • The Low-Redshift Lyman Continuum Survey Unveiling the ISM properties of low-z Lyman-continuum emitters
  • 2022
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 663
  • Journal article (peer-reviewed)abstract
    • Aims. Combining 66 ultraviolet (UV) spectra and ancillary data from the recent Low-Redshift Lyman Continuum Survey (LzLCS) and 23 LyC observations by earlier studies, we form a statistical sample of star-forming galaxies at z similar to 0.2-0.4 with which we study the role of cold interstellar medium (ISM) gas in the leakage of ionizing radiation. We also aim to establish empirical relations between the H I neutral and low-ionization state (LIS) absorption lines with different galaxy properties.Methods. We first constrain the massive star content (stellar ages and metallicities) and UV attenuation by fitting the stellar continuum with a combination of simple stellar population models. The models, together with accurate LyC flux measurements, allow us to determine the absolute LyC photon escape fraction for each galaxy (f(esc)(abs)). We then measure the equivalent widths and residual fluxes of multiple H I and LIS lines, and the geometrical covering fraction of the UV emission, adopting the picket-fence model.Results. The LyC escape fraction spans a wide range, with a median f(esc)(abs) (0.16, 0.84 quantiles) of 0.04 (0.02, 0.20), and 50 out of the 89 galaxies detected in the LyC (1 sigma upper limits of f(esc)(abs) less than or similar to 0.01 for non-detections, typically). The H I and LIS line equivalent widths scale with the UV luminosity and attenuation, and inversely with the residual flux of these lines. Additionally, Ly alpha equivalent widths scale with both the H I and LIS residual fluxes, but anti-correlate with the corresponding H I or LIS equivalent widths. The H I and LIS residual fluxes are correlated, indicating that the neutral gas is spatially traced by the low-ionization transitions. We find that the observed trends of the absorption lines and the UV attenuation are primarily driven by the geometric covering fraction of the gas. The observed nonuniform gas coverage also demonstrates that LyC photons escape through low-column-density channels in the ISM. The equivalent widths and residual fluxes of both the H I and LIS lines strongly correlate with f(esc)(abs): strong LyC leakers (highest f(esc)(abs)) show weak absorption lines, low UV attenuation, and large Ly alpha equivalent widths. We provide several empirical calibrations to estimate f(esc)(abs) from UV absorption lines. Finally, we show that simultaneous UV absorption line and dust attenuation measurements can, in general, predict the escape fraction of galaxies. We apply our method to available measurements of UV LIS lines of 15 star-forming galaxies at z similar to 4 6 (plus 3 high-z galaxy composites), finding that these high-redshift, UV-bright galaxies (M-UV less than or similar to 21) may have low escape fractions, f(esc)(abs) less than or similar to 0.1.Conclusions. UV absorption lines trace the cold ISM gas of galaxies, which governs the physics of the LyC escape. We show that, with some assumptions, the absolute LyC escape can be statistically predicted using UV absorption lines, and the method can be applied to study galaxies across a wide redshift range, including in the epoch of cosmic reionization.
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14.
  • Wang, Bingjie, et al. (author)
  • The Low-redshift Lyman-continuum Survey : [S ii] Deficiency and the Leakage of Ionizing Radiation
  • 2021
  • In: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 916:1
  • Journal article (peer-reviewed)abstract
    • The relationship between galaxy characteristics and the reionization of the universe remains elusive, mainly due to the observational difficulty in accessing the Lyman continuum (LyC) at these redshifts. It is thus important to identify low-redshift LyC-leaking galaxies that can be used as laboratories to investigate the physical processes that allow LyC photons to escape. The weakness of the [S ii] nebular emission lines relative to typical star-forming galaxies has been proposed as a LyC predictor. In this paper, we show that the [S ii] deficiency is an effective method to select LyC-leaking candidates using data from the Low-redshift LyC Survey, which has detected flux below the Lyman edge in 35 out of 66 star-forming galaxies with the Cosmic Origins Spectrograph on board the Hubble Space Telescope. We show that LyC leakers tend to be more [S ii] deficient and that the fraction of their detections increases as [S ii] deficiency becomes more prominent. Correlational studies suggest that [S ii] deficiency complements other LyC diagnostics (such as strong Lyα emission and high [O iii]/[O ii]). Our results verify an additional technique by which reionization-era galaxies could be studied.
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16.
  • Zimmermann, Sandra E., et al. (author)
  • The phosphorylated pathway of serine biosynthesis links plant growth with nitrogen metabolism
  • 2021
  • In: Plant Physiology. - : Oxford University Press. - 0032-0889 .- 1532-2548. ; 186:3, s. 1487-1506
  • Journal article (peer-reviewed)abstract
    • Because it is the precursor for various essential cellular components, the amino acid serine is indispensable for every living organism. In plants, serine is synthesized by two major pathways: photorespiration and the phosphorylated pathway of serine biosynthesis (PPSB). However, the importance of these pathways in providing serine for plant development is not fully understood. In this study, we examine the relative contributions of photorespiration and PPSB to providing serine for growth and metabolism in the C3 model plant Arabidopsis thaliana. Our analyses of cell proliferation and elongation reveal that PPSB-derived serine is indispensable for plant growth and its loss cannot be compensated by photorespiratory serine biosynthesis. Using isotope labeling, we show that PPSB-deficiency impairs the synthesis of proteins and purine nucleotides in plants. Furthermore, deficiency in PPSB-mediated serine biosynthesis leads to a strong accumulation of metabolites related to nitrogen metabolism. This result corroborates N-15-isotope labeling in which we observed an increased enrichment in labeled amino acids in PPSB-deficient plants. Expression studies indicate that elevated ammonium uptake and higher glutamine synthetase/glutamine oxoglutarate aminotransferase (GS/GOGAT) activity causes this phenotype. Metabolic analyses further show that elevated nitrogen assimilation and reduced amino acid turnover into proteins and nucleotides are the most likely driving forces for changes in respiratory metabolism and amino acid catabolism in PPSB-deficient plants. Accordingly, we conclude that even though photorespiration generates high amounts of serine in plants, PPSB-derived serine is more important for plant growth and its deficiency triggers the induction of nitrogen assimilation, most likely as an amino acid starvation response.
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