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  • Erosa-Rejon, Gilda J., et al. (author)
  • Benzochromenes from the roots of Bourreria pulchra
  • 2010
  • In: Phytochemistry Letters. - : Elsevier BV. - 1874-3900. ; 3:1, s. 9-12
  • Journal article (peer-reviewed)abstract
    • Two new benzochromenes, (6,6-dimethyl-2-methoxy-6H-benzo[c]chromen-9-yl)methanol (1), and 2-methoxy-6,6-dimethyl-6H-benzo[c]chromen-9-carbaldehyde (2), together with several already known metabolites, were isolated from the root extract of Bourreria pulchra (Boraginaceae). The structures of 1 and 2 were established on the basis of their spectroscopic data. Both were assayed for in vitro antiprotozoan activity, and especially 1 was found to possess significant activity against Leishmania mexicana and Trypanosoma cruzi parasites (IC50 4.6 mu g/mL and 7.5 mu g/mL, respectively). (C) 2009 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Sterner, Olov (1)
Salamanca, Efrain (1)
Pena-Rodriguez, Luis ... (1)
Erosa-Rejon, Gilda J ... (1)
Yam-Puc, Alejandro (1)
Chan-Bacab, Manuel J ... (1)
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Gimenez-Turbax, Albe ... (1)
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University
Lund University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Natural sciences (1)
Year
2010 (1)

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