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| 3. |
- Boy, M., et al.
(author)
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Interactions between the atmosphere, cryosphere, and ecosystems at northern high latitudes
- 2019
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In: Atmospheric Chemistry and Physics. - : Copernicus GmbH. - 1680-7316 .- 1680-7324. ; 19:3, s. 2015-2061
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Journal article (peer-reviewed)abstract
- The Nordic Centre of Excellence CRAICC (Cryosphere-Atmosphere Interactions in a Changing Arctic Climate), funded by NordForsk in the years 2011-2016, is the largest joint Nordic research and innovation initiative to date, aiming to strengthen research and innovation regarding climate change issues in the Nordic region. CRAICC gathered more than 100 scientists from all Nordic countries in a virtual centre with the objectives of identifying and quantifying the major processes controlling Arctic warming and related feedback mechanisms, outlining strategies to mitigate Arctic warming, and developing Nordic Earth system modelling with a focus on short-lived climate forcers (SLCFs), including natural and anthropogenic aerosols. The outcome of CRAICC is reflected in more than 150 peer-reviewed scientific publications, most of which are in the CRAICC special issue of the journal Atmospheric Chemistry and Physics. This paper presents an overview of the main scientific topics investigated in the centre and provides the reader with a state-of-the-art comprehensive summary of what has been achieved in CRAICC with links to the particular publications for further detail. Faced with a vast amount of scientific discovery, we do not claim to completely summarize the results from CRAICC within this paper, but rather concentrate here on the main results which are related to feedback loops in climate change-cryosphere interactions that affect Arctic amplification.
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| 4. |
- Ahlberg, Erik, et al.
(author)
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"Vi klimatforskare stödjer Greta och skolungdomarna"
- 2019
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In: Dagens nyheter (DN debatt). - 1101-2447.
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Journal article (pop. science, debate, etc.)abstract
- DN DEBATT 15/3. Sedan industrialiseringens början har vi använt omkring fyra femtedelar av den mängd fossilt kol som får förbrännas för att vi ska klara Parisavtalet. Vi har bara en femtedel kvar och det är bråttom att kraftigt reducera utsläppen. Det har Greta Thunberg och de strejkande ungdomarna förstått. Därför stödjer vi deras krav, skriver 270 klimatforskare.
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| 7. |
- Andersson, Maria, et al.
(author)
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External mirroring of inner chaos : Blogging as experienced by the relatives of people with cancer
- 2013
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In: International Journal of Palliative Nursing. - 1357-6321 .- 2052-286X. ; 19:1, s. 16-23
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Journal article (peer-reviewed)abstract
- Background: Relatives of a person suffering from cancer risk being affected both physically and psychologically. Blogging has become increasingly popular as a forum for communicating experiences, but few studies have focused on what blogging about a relative's cancer journey means to the author. Aim: To illuminate relatives' experiences of blogging when a family member is in the end-of-life phase of cancer. Method: Telephone interviews were conducted with 12 people about their experiences of blogging during and after their family member's illness. The data was analysed using qualitative content analysis. Findings: Blogging facilitated everyday life, introduced the relatives to new friends with similar experiences, helped them in their grief process, and helped them to preserve memories. The negative aspects were being misunderstood and publicly criticised as well as the feeling of providing readers with 'reality show' entertainment. Conclusion: Blogging was seen as a complement to professional care that contributed to the prevention of ill health.
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| 8. |
- Axelsson, Josefine, 1992-
(author)
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Interglacial climates in proxies and models : Utilizing sampled oxygen isotopes and model simulations to understand past Indian summer monsoon variability
- 2024
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Doctoral thesis (other academic/artistic)abstract
- The study of Earth's climate system, including the mechanisms driving monsoon systems, is a key area of research within environmental sciences. Monsoons, vital for billions of people, are complex atmospheric phenomena influenced by various global factors, including orbital changes and natural climate variability. Among monsoon systems, the Indian summer Monsoon (ISM) is of particular interest due to its significant impact on the South Asian climate, agriculture, and water resources. Despite extensive study, comprehending the ISM's historical variability and its future implications remains a challenge. Utilizing natural archives like speleothems, along with stable water isotopes from precipitation and advanced climate model simulations, this thesis aims to decipher the ISM's responses to natural forcings across key interglacial periods—the Last Interglacial and the Holocene.Our findings indicate that the ISM's strength is critically influenced by slight variations in orbital configurations, leading to significant shifts in monsoon patterns. Our research also highlights the dual influence of local geographical features and distant atmospheric conditions on the ISM's annual variability. Most notably, we observed discrepancies between δ18O values obtained from isotope-enabled climate models and those derived from speleothems. This insight indicates that the models need refinement to accurately mirror the complexities observed in the proxy records and that the uncertainty parameter in speleothem records needs to be improved.The alignment between proxy and model data is crucial for a more accurate reconstruction of past climates and for enhancing the predictive capabilities of future monsoon behavior under changing climatic conditions. By advancing our knowledge of the ISM's past, we are better equipped to anticipate its future. To achieve that, this thesis stresses the importance of bridging the gap between proxy data insights and climate model simulations. This would not only enrich our historical climate knowledge but also inform future climate projections, highlighting the indispensable role of interdisciplinary research in climate science challenges.
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| 10. |
- Bengtsson, Jörgen, et al.
(author)
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The influence of age on the distribution of morphine and morphine-3-glucuronide across the blood-brain barrier in sheep
- 2009
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In: British Journal of Pharmacology. - : Wiley. - 0007-1188 .- 1476-5381. ; 157:6, s. 1085-1096
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Journal article (peer-reviewed)abstract
- Background and purpose The effect of age on the distribution of morphine and morphine-3-glucuronide (M3G) across the blood-brain barrier (BBB) was studied in a sheep model utilizing intracerebral microdialysis. The effect of neonatal asphyxia on brain drug distribution was also studied. Experimental approach Microdialysis probes were inserted into the cortex, striatum and blood of 11 lambs (127 gestation days) and six ewes. Morphine, 1 mg.kg(-1), was intravenously administered as a 10 min constant infusion. Microdialysis and blood samples were collected for up to 360 min and analysed using liquid chromatography-tandem mass spectrometry. The half-life, clearance, volume of distribution, unbound drug brain : blood distribution ratio (K(p,uu)) and unbound drug volume of distribution in brain (V(u,brain)) were estimated. Key results Morphine K(p,uu) was 1.19 and 1.89 for the sheep and premature lambs, respectively, indicating that active influx into the brain decreases with age. Induced asphyxia did not affect transport of morphine or M3G across the BBB. Morphine V(u,brain) measurements were higher in sheep than in premature lambs. The M3G K(p,uu) values were 0.27 and 0.17 in sheep and premature lambs, indicating a net efflux from the brain in both groups. Conclusions and implications The morphine K(p,uu) was above unity, indicating active transport into the brain; influx was significantly higher in premature lambs than in adult sheep. These results in sheep differ from those in humans, rats, mice and pigs where a net efflux of morphine from the brain is observed.
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| 12. |
- Berg, Lotta, et al.
(author)
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Digital tillsynsteknik i djurhållning utomhus
- 2020
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Reports (other academic/artistic)abstract
- I enlighet med Jordbruksverkets förfrågan behandlar denna rapport tre områden för digital teknik vid övervakning och kontroll av djur som vistas utomhus på stora ytor: (1) kamerateknologi, t.ex. användning av drönare, (2) positioneringsteknologi som GPS och (3) teknologi för att styra djurens rörelser, som drivning med drönare och användning av s.k. virtuella stängsel. De tre teknikområdena överlappar delvis varandra. Digital tillsyn av utegående djur är beroende av att sensorer mäter det man tror att de mäter med tillräcklig noggrannhet och att data kan överföras och bearbetas till information som lagras och analyseras på ett säkert och korrekt sätt. Sådana teknologier benämns med samlingsnamnet ’Precision Livestock Farming’ (PLF). Användningen av informationen är avgörande för teknikens användbarhet i tillsyns- och djurskyddsarbete. Tillämpningarna är till viss del reglerade av gällande lagstiftning, exempelvis genom krav på tillsyn, begränsad användning av elektricitet för att styra djurs beteende, användning av obemannade luftfarkoster, d.v.s. drönare, samt åtgärder för att förhindra att utrustning skadar djuren eller påverkar deras hälsa och beteende. Inom PLF används en rad olika sensorer som direkt eller indirekt kan mäta djurens miljö och djurens beteende och fysiologiska tillstånd. Den teknologiska utvecklingen har främst varit inriktad på mjölkkor, fjäderfän och grisar och endast i liten utsträckning berört häst, får och get. För djur på bete är överföringen av data från en enhet på eller vid djuret till en mottagare särskilt problematisk p.g.a. stora avstånd, men det sker en snabb teknisk utveckling mot effektivare överföring. PLF-teknologin innebär i de flesta fall att djuren övervakas kontinuerligt och att avvikelser i t.ex. deras hälsotillstånd och välfärd i princip kan upptäckas i realtid, vilket ska ställas mot nuvarande lagkrav på tillsyn minst en eller två gånger dagligen. Sensorer kan ge information om ett stort antal fysiologiska tillstånd och beteenden. En av de vanligaste teknikerna är sensorer för aktivitet. Indirekt kan de också ge information om idissling, liggtid, stegantal och ättid och utlösa larm om exempelvis brunst, hälsoproblem, hälta och kalvning. Sensorer kan även placeras i förmagen hos idisslare (s.k. våmbolus) där de mäter våm-pH och kan larma om störningar i magfunktionen, eller utformas som termometrar som kan larma om hälsostörningar, kalvning och vattenintag eller mikrofoner som kan mäta idissling och larma om brunst, kalvning och onormalt idisslingsmönster. Med kamerateknik kan man mäta aktivitet, kroppsform och hudtemperatur, vilket kan ge information om ketosstatus, hull, hälta och juverhälsa. Kameror monterade på drönare kan användas för att lokalisera och räkna djur, bestämma deras position, habitatval och till viss del deras beteende, särskilt när djuren rör sig över stora arealer. Det finns flera elektroniska positioneringsteknologier varav passiv ’Radio Frequency Identification RFID’ är den vanligaste. Räckvidden är kort med denna teknik men den kan vara användbar om man t.ex. vill mäta hur ofta djuren besöker en vattenpost. Andra teknologier kan med hjälp av antenner följa djurens positioner i realtid. GPS-enheter monterade i halsband kan regelbundet registrera djurens geografiska position. Användningen av GPS har blivit relativt vanlig i renskötseln vilket tycks ha lett till en förbättrad arbetssituation för renskötarna. Positionering med GPS ger inte alltid exakta uppgifter men tekniken har visat sig användbar för studier av habitatval, sociala interaktioner och gruppdynamik. Med positionerna från GPS har man också kunnat styra djur till områden med bättre betestillgång. Med en tillräckligt frekvent bestämning av position med hjälp av GPS (ca en gång per minut) är det möjligt att bestämma betestiden för nötkreatur på ett tillförlitligt sätt. En användning av drönare i djurskötsel och djurtillsyn kan vara att med hjälp av kamera lokalisera djuren över stora ytor. Denna användning begränsas dock av nuvarande bestämmelser om att föraren måste ha ögontakt med drönaren. I renskötseln har drönare börjat användas för att förflytta djur men denna tillämpning är ännu inte juridiskt reglerad. Virtuella stängsel är strukturer som bestäms med kartkoordinater eller elektronisk sändare på marken. Stängslen fungerar som inhägnader, hinder eller gränser. Djuren mottar signaler (vanligen ljud) och stimuli (vanligen elstötar från ett halsband) som gör det möjligt för dem att lära sig var stängslet finns. I vetenskapliga studier har man med varierande framgång lyckats lära djuren att associera ljudsignaler och elstötar med en gräns som inte får passeras. Förmågan att lära sig skiljer mellan olika djurslag, liksom mellan individer. Det finns fortfarande många obesvarade frågeställningar om hur djur kan anpassa sig till virtuella stängselsystemet, liksom hur de påverkas, både under inlärningsfas och bruksfas.
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| 13. |
- Berg, Lotta, et al.
(author)
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Djurskydd inom grisuppfödning
- 2020
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Reports (other academic/artistic)abstract
- I Sverige tillåts idag generellt avvänjning av smågrisar i praktiken vid en individuell ålder om tidigast 28 dagar. Detta skiljer från EUs grisdirektiv där avvänjning tillåts från 21 dagars ålder. En digivningsperiod på 21 dagar ger en högre produktion eftersom medeltalet kullar per sugga och år teoretiskt då kan öka med 4,5 % (från 2,2 till 2,3 kullar per år). Det har även föreslagits att en kortare digivningsperiod skulle innebära mindre påfrestningar på suggorna, och därigenom medföra förbättrad välfärd för dessa. Rådet finner att det finns mycket få studier som jämför avvänjning vid just 21 och 28 dagar. De vetenskapliga studier som studerar detta mer i detalj är i de flesta fall genomförda i alternativa system, så som grupphållnings-system eller så kallade ”getaway pens” där suggan kan gå ifrån sina smågrisar. Resultat från dessa studier går därmed inte att generalisera till konventionella system där suggor med smågrisar hålls individuellt med små möjligheter för suggan att reglera t.ex. digivning eller födosöksbeteende. Trots bristen på vetenskapligt granskade rapporter konstaterades att en avvänjning vid 28 dagars ålder var att föredra sett ur smågrisens perspektiv, eftersom matsmältningsapparat och immunsystem är mer utvecklade den fjärde levnadsveckan. Det förefaller dock finnas en ganska tydlig skillnad i fysiologisk mognad mellan grisar som är yngre (<19-21 dagar) respektive äldre (28 dagar), men där grisar som är 25 dagar och äldre skiljer sig mindre från grisar som är 28 dagar gamla än grisar som är 23 dagar och yngre. Diperiodens belastning på den domesticerade suggan i modern grisproduktion överstiger den hos frilevande suggor eftersom antalet överlevande kultingar är högre, samt att suggan inte heller genom att styra digivningen kan skydda sig från kullens ökande krav på att dia. De ökande kullstorlekarna kan teoretiskt innebära påfrestningar på suggan, och tidig avvänjning skulle därmed kunna bidra till att minska påfrestningarna på suggan. Det finns dock inga vetenskapliga studier som stödjer en sådan slutsats. Det kan dock konstateras att en svensk sugga under slutet av diperioden i medeltal ger di till 13 kultingar som vardera väger cirka 10 kg, vilka tillsammans dagligen kräver 108 MJ omsättbar energi (25 800 kcal) varav huvuddelen kommer från suggans mjölk. I dagens svenska grisproduktion med omgångsuppfödning kan det skilja 4-7 dagar mellan de först födda och de sist födda i gruppen. För att samla sugg-gruppen inför nästa grisning avvänjs alla suggor samma dag och vid en lägsta individuell avvänjningsålder av 28 dagar blir medelåldern vid avvänjning därför i praktiken cirka 32 dagar. Om lantbruken fortsätter att fokusera på avvänjning så nära 28 dagars ålder som möjligt kommer ”manöverutrymmet” för att synkronisera suggorna vid avvänjning att försvinna. Suggor med fysiologiskt längre dräktighet än genomsnittet riskerar då att förskjutas i grisningstid jämfört med medelsuggorna. Vid en förlängning med tre dagar mellan två grisningstillfällen kan en sugga redan som tredjegrisare vara så pass avvikande vad gäller grisningsdag att hon kommer att slås ut (slaktas) i förtid om det inte ges möjlighet att synkronisera gruppen vid avvänjning. Vid en bedömning av lämpligaste dagen för avvänjning bör såväl smågrisens som suggans situation beaktas. Det vetenskapliga underlaget för detta är mycket begränsat, men det ska beaktas att inhysning och skötsel har större betydelse för såväl smågrisars som suggors hälsa och välfärd än den exakta avvänjningsåldern. Vid en samlad bedömning ansågs därför att en avvänjning vid 28 dagar i genomsnitt förefaller acceptabel, under förutsättning att avvänjningsåldern i inget enskilt fall understiger 25 dagar.
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| 14. |
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| 15. |
- Berg, Lotta, et al.
(author)
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Minkhållning i Sverige
- 2020
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Reports (other academic/artistic)abstract
- Den här rapporten är framtagen av SLUs vetenskapliga råd för djurskydd i syfte att utvärdera djurvälfärden hos minkar inom svensk pälsdjursproduktion och bedöma om den vetenskapliga litteraturen ger stöd för att produktionen, så som den bedrivs i dag, ger djuren möjlighet att bete sig naturligt. Minkar som föds upp för pälsproduktion i Sverige måste hållas och skötas enligt Statens jordbruksverks föreskrifter och allmänna råd (SJVFS 2012:14) om uppfödning och hållande av pälsdjur. Rapporten har tagits fram på uppdrag av Jordbruksverket som en del i ett regeringsuppdrag om minkhållning. Den beskriver minkens ursprung och domesticering, naturligt beteende hos vild mink, inhysning och skötsel vid pälsuppfödning, onormalt beteende, miljöberikningar, smittskydd, förekommande sjukdomar och avlivningsmetoder. I rapporten ges rekommendationer baserat på tillgänglig vetenskaplig litteratur, och behov av framtida forskning identifieras.Minken är en opportunistisk köttätare som behöver äta relativt ofta. I pälsdjursproduktionen tillämpas i princip fri tillgång på foder till digivande honor och växande valpar men inför parningssäsongen innebär den fria tillgången ökad risk för komplikationer vid valpningen på grund av övervikt hos honan. Fodringen behöver därför anpassas under vintern för att minska risken för feta honor och därmed ökad dödlighet vid valpningen. Neddragen fodertillgång kan orsaka frustration som då visar sig i beteendestörningar. Olika aspekter på utfodring bör därför beaktas i framtida forskning. Den vilda minken lever solitärt under stora delar av året, dock kan en till flera honor leva inom en hanes revir. I pälsdjursproduktionen bör därför vuxna minkar hållas individuellt, undantaget är växande ungminkar som med fördel kan hållas tillsammans. Att hålla två minkar tillsammans är det vanligaste, dock fungerar det att hålla tre ungminkar i etagebur om de ges extra foder och god tillsyn. Grupper med fler än tre djur bör undvikas då riskerna för aggression ökar. En lya fastsatt utanpå buren är viktigt för alla minkar året runt då de naturligt vilar mycket i sina bohål, samt även för att minkhonan ska kunna ta hand om de outvecklade ungarna första tiden efter födelsen. I fångenskap används halm för att skapa ett varmt bo under den kalla årstiden samt för att bygga ett bo för ungarna under uppfödningsperioden.Systematisk genetisk selektion för önskat beteende (temperament) förbättrar välfärden hos minken. Systemet tillämpas på svenska gårdar genom att minkar som uppvisar rädsla eller stress selekteras bort vid avelsurvalet. Urvalet av avelsdjur görs kontinuerligt från det att valparna föds, då reproduktion, valpöverlevnad och temperament registreras tidigt och är viktiga parametrar att ta hänsyn till i urvalet. Det slutliga urvalen sker på hösten då längd, vikt och pälsegenskaper graderas. Ju tidigare dessa urval görs desto tidigare kan utfodringen anpassas för att undvika att avelsdjuren blir överviktiga under hösten. Det är viktigt att aveln inte resulterar i för stora djur, då detta kan leda till välfärdsproblem i framtiden.Mink i vilt tillstånd använder vatten i sin jakt på bytesdjur, men är inget vattenlevande djur, per se. Badvatten till mink bedöms däremot vara en positiv berikning, dock inte vetenskapligt belagt, som ett grundläggande beteendebehov. Forskning visar att beteendestörningar kan förebyggas genom att minkarna ges fri tillgång på foder, hålls i etageburar med bolåda, hyllor, strömedel och berikningar som byts ut regelbundet. I svenska djurskyddsföreskrifter ingår dessa som krav för hållande av mink för pälsdjursproduktion. Mer kunskap behövs för hur ofta berikningar bör skiftas.Djurvälfärd i samband med livdjurstransport och avlivning av mink lyfts fram som angelägna forskningsområden. En snabb avlivning vid hemmaburen bedöms vara det bästa ur djurvälfärdssynpunkt. För att minska risken för spridning av sjukdomar bör importerade minkar hållas i karantän och hög biosäkerhet tillämpas på gården.
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| 16. |
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| 17. |
- Berg, Lotta, et al.
(author)
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Yttrande från SLUs vetenskapliga råd för djurskydd om djurskydd inom grisuppfödning
- 2019
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Other publication (other academic/artistic)abstract
- Detta yttrande svarar på följande fråga av Djurskyddet Sverige, Svenska Djurskyddsföreningen, Djurens Rätt, World Animal Protection Sverige, Compassion in World Farming Sverige och Vi Konsumenter, som vänt sig till det vetenskapliga rådet med anledning av Jordbruksverkets ändring av djurskyddsbestämmelserna för gris, Statens jordbruksverks föreskrifter och allmänna råd m ( SJVFS 2017:25) om grishållning inom lantbruket m.m., saknr. L 106: Är det förenat med bättre, likvärdig eller sämre djurvälfärd, vid en sammantagen bedömning av såväl smågrisens välfärd som suggans, om smågrisar avvänjs från suggan vid 21 dagars ålder i stället för vid 28 dagars ålder? Rådet ombads att belysa frågan utifrån ett brett perspektiv innefattande såväl psykisk som fysisk hälsa och välbefinnande.
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| 18. |
- Berg, Lotta, et al.
(author)
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Yttrande från SLUs vetenskapliga råd för djurskydd om hållande av hund och katt
- 2018
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Other publication (other academic/artistic)abstract
- Detta yttrande är skrivet på uppdrag av Jordbruksverket i samband med verkets översyn av föreskrifterna för hund och katt. För att Jordbruksverkets föreskrifter ska vara väl förankrade i den senaste forskningen önskar verket inhämta underlag från det vetenskapliga rådet för djurskydd vid Sveriges lantbruksuniversitet, specifikt gällande områdena rörelsebehov, social kontakt och avvänjning.
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| 19. |
- Berggren, Ann-Marie, et al.
(author)
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Variability of Be-10 and delta O-18 in snow pits from Greenland and a surface traverse from Antarctica
- 2013
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In: Nuclear Instruments and Methods in Physics Research Section B. - : Elsevier BV. - 0168-583X .- 1872-9584. ; 294, s. 568-572
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Journal article (peer-reviewed)abstract
- To examine temporal variability of Be-10 in glacial ice, we sampled snow to a depth of 160 cm at the NEEM (North Greenland Eemian Ice Drilling) drilling site in Greenland. The samples span three years between the summers of 2006 and 2009. At the same time, spatial variability of Be-10 in glacial ice was explored through collection of the upper similar to 5 cm of surface snow in Antarctica during part of the Swedish-Japanese traverse from Svea to Syowa station during the austral summer in 2007-2008. The results of the Greenlandic 1 Be snow suggested variable concentrations that apparently do not clearly reflect the seasonal change as indicated by the delta O-18 data. The Be-10 concentration variability most likely reflects also effects of aerosol loading and deposition pathways, possibly in combination with post-depositional processes. The Antarctic traverse data expose a negative correlation between Be-10 and delta O-18, while there are weaker but still significant correlations to altitude and distance to the coast (approximated by the distance to the 70th latitude). These relationships indicate that geographical factors, mainly the proximity to the coast, may strongly affect 1 Be concentrations in snow in Queen Maud Land, Antarctica.
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| 20. |
- Bergkvist, Göran, et al.
(author)
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Red fescue undersown in winter wheat suppresses Elytrigia repens
- 2010
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In: Weed Research. - : Wiley. - 0043-1737 .- 1365-3180. ; 50, s. 447-455
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Journal article (peer-reviewed)abstract
- P>Elytrigia repens (syn. Elymus repens) is a perennial grass weed that is controlled by herbicides or by tillage. Both methods are expensive and may have negative effects on the environment. Therefore, alternative methods of weed control, such as using competition from under-sown perennial forage crops, are of interest. Red fescue can be sown together with winter wheat as a non-flowering understorey crop that has its main growth during late summer and autumn. This study quantified the effect of red fescue and E. repens on wheat biomass and tested the hypothesis that under-sown red fescue reduces the amount of E. repens rhizomes and thus the need for herbicides or tillage. Two field experiments in which winter wheat, red fescue and E. repens were grown in all possible combinations were conducted between 2003 and 2005. Elytrigia repens reduced wheat biomass by 8%, while red fescue had no significant effect on wheat biomass. Red fescue reduced late autumn biomass of E. repens rhizomes by 40%. The results suggest that red fescue sown with winter wheat can reduce propagation of E. repens during summer and autumn, without a significant reduction in wheat biomass.
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| 21. |
- Dackehag, Margareta, et al.
(author)
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Taxation of Dividend Income and Economic Growth: The Case of Europe
- 2015
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Other publication (other academic/artistic)abstract
- More recently researchers have turned to analyze how the tax structure, rather than the overall tax level, affects economic performance. For instance, several papers have investigated how taxation on corporate and individual (labor) income influences growth. Taxation of dividend income may also influence growth via its impact on investments and firm behavior. Within the academic community there is conflicting views about the impact taxation of dividends has on firm behavior and, hence, on economic performance. According to the “traditional view”, taxation of dividends is distortionary and increases the cost of equity. According to the “new view”, taxation of dividends does not influence the marginal cost of capital and consequently has no impact on investment decisions. To our knowledge, this paper is the first study to explore how tax rates on dividends affect economic growth, by using panel data from 1990 till 2008 for 18 European countries. We find that taxation of dividend income negatively influences economic growth, a result that corroborates the old view of dividends taxation as distortionary and also has some policy implication for the European countries in question.
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| 22. |
- Dackehag, Margareta, et al.
(author)
-
Taxation of Income and Economic Growth: An Empirical Analysis of 25 Rich OECD Countries
- 2012
-
Other publication (other academic/artistic)abstract
- Several empirical papers have studied the effect of government size, typically measured as government expenditures, on economic growth. There is no consensus on the direction of this impact, even though more recent studies tend to find a negative relationship between the general level of government expenditures and economic growth. This negative relationship is explained by the distortions that raising tax revenues cause on economic activities. There are, however, several ways to raise tax revenues that likely have different distortionary effects and, hence, may impact economic growth differently. This paper analyses how taxation of income influences economic growth. More precisely we study how statutory tax rates on corporate and personal income affect economic growth by using panel data from 1975 till 2010 for 25 rich OECD countries. We find that both taxation of corporate and personal income negatively influence economic growth. The correlation between corporate income taxation and economic growth is more robust, however.
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| 23. |
- Dahl-Jensen, D., et al.
(author)
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Eemian interglacial reconstructed from a Greenland folded ice core
- 2013
-
In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 493:7433, s. 489-494
-
Journal article (peer-reviewed)abstract
- Efforts to extract a Greenland ice core with a complete record of the Eemian interglacial (130,000 to 115,000 years ago) have until now been unsuccessful. The response of the Greenland ice sheet to the warmer-than-present climate of the Eemian has thus remained unclear. Here we present the new North Greenland Eemian Ice Drilling ('NEEM') ice core and show only a modest ice-sheet response to the strong warming in the early Eemian. We reconstructed the Eemian record from folded ice using globally homogeneous parameters known from dated Greenland and Antarctic ice-core records. On the basis of water stable isotopes, NEEM surface temperatures after the onset of the Eemian (126,000 years ago) peaked at 8 +/- 4 degrees Celsius above the mean of the past millennium, followed by a gradual cooling that was probably driven by the decreasing summer insolation. Between 128,000 and 122,000 years ago, the thickness of the northwest Greenland ice sheet decreased by 400 +/- 250 metres, reaching surface elevations 122,000 years ago of 130 +/- 300 metres lower than the present. Extensive surface melt occurred at the NEEM site during the Eemian, a phenomenon witnessed when melt layers formed again at NEEM during the exceptional heat of July 2012. With additional warming, surface melt might become more common in the future.
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| 24. |
- de Woul, Mattias, 1972-
(author)
-
Response of glaciers to climate change : Mass balance sensitivity, sea level rise and runoff
- 2008
-
Doctoral thesis (other academic/artistic)abstract
- The purpose of this study is to enhance our understanding of the response of glaciers to climate change. Global sea level is affected by changes in glacier ice volume, and melt-water from glaciers is a principal water source in many regions. This study applies glacier mass balance modelling, with varying complexity and spatial resolution, ranging from individual glaciers to regional and global assessments of glacier mass losses. Glaciers located in maritime environments generally show considerably higher mass balance sensitivities than those in continental settings. On average, an assumed increase in annual precipitation of +10% tends to offset the effect of an annual temperature change of +1 K, by roughly 20%. Two case studies, at Storglaciären, Sweden, and Hofsjökull, Iceland, involve model results of future mass balance change and glacier melt induced changes in runoff. Applying a temperature and precipitation scenario for Iceland in 2050 results in increased total runoff from Hofsjökull by roughly one third, and results emphasize the role of the firn layer in delaying water flow through glaciers, yielding a redistribution of discharge within the year. Based on a global gridded data set of glacierized area, the sea level equivalent from all mountain glaciers and ice caps outside the ice sheets in Greenland and Antarctica during 1961–2004, caused by changes in temperature and precipitation, is estimated to be 0.58±0.34 mm a–1. The mountain glaciers and ice caps around Antarctica alone contribute almost 40% of the global estimate, and hence their contribution is considerably larger than previously assumed.
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| 25. |
- Delmonte, Barbara, et al.
(author)
-
Aeolian dust in East Antarctica (EPICA-Dome C and Vostok): provenance during glacial ages over the last 800 kyr.
- 2008
-
In: GEOPHYSICAL RESEARCH LETTERS. - 0094-8276. ; 35:7
-
Journal article (peer-reviewed)abstract
- Aeolian mineral dust archived in Antarctic ice cores represents a key proxy for Quaternary climate evolution. The longest and most detailed dust and climate sequences from polar ice are provided today by the Vostok and by the EPICA-Dome C (EDC) ice cores. Here we investigate the geographic provenance of dust windborne to East Antarctica during Early and Middle Pleistocene glacial ages using strontium and neodymium isotopes as tracers. The isotopic signature of Antarctic dust points towards a dominant South American origin during Marine Isotopic Stage (MIS) 8, 10, 12, and back to MIS 16 and 20 as deduced from EDC core. Data provide evidence for a persistent overall westerly circulation pattern allowing efficient transfer of dust from South America to the interior of Antarctica over the last 800 kyr. Some small but significant dissimilarity between old and recent glacial ages suggests a slightly reduced Patagonian contribution during ancient glaciations.
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| 26. |
- Delmonte, Barbara, et al.
(author)
-
Aeolian dust in the Talos Dome ice core (East Antarctica, Pacific/Ross Sea sector) : Victoria Land versus remote sources over the last two climate cycles
- 2010
-
In: Journal of Quaternary Science. - : Wiley. - 0267-8179 .- 1099-1417. ; 25:8, s. 1327-1337
-
Journal article (peer-reviewed)abstract
- A new ice core (TALDICE) drilled at Tabs Dome (East Antarctica, Ross Sea sector) preserves a ca. 250 ka long record of palaeoclimate and atmospheric history. We investigate dust variability and provenance at the site during glacial periods and the Holocene through the Sr-Nd isotopic composition of ice core dust and potential source areas (PSA). We provide new isotopic data on dust sources from Victoria Land such as regoliths, glacial drifts, aeolian sands and beach deposits. Some of these sources are located at high altitude and are known to have been ice free throughout the Pleistocene. The major features of the TALDICE dust record are very similar to those from central East Antarctica. During glacial times, South America was the dominant dust supplier for Tabs Dome as well as for the entire East Antarctic plateau. Conversely, during the Holocene the principal input of mineral dust at Tabs Dome probably derives from proximal sources which are the ice-free areas of northern Victoria Land, located at similar altitude with respect to the drilling site. Atmospheric mobilisation of dust from these neighbouring areas and transport inland to Tabs Dome can be ultimately associated with advection of maritime air masses from the Pacific/Ross Sea region. Copyright (C) 2010 John Wiley & Sons, Ltd.
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| 27. |
- Delmonte, Barbara, et al.
(author)
-
Holocene dust in East Antarctica : Provenance and variability in time and space
- 2020
-
In: The Holocene. - : SAGE Publications. - 0959-6836 .- 1477-0911. ; 30:4, s. 546-558
-
Journal article (peer-reviewed)abstract
- In this paper, we provide a comprehensive overview of the state-of-knowledge of dust flux and variability in time and space in different sectors of East Antarctica during the Holocene. By integrating the literature data with new evidences, we discuss the dust flux and grain-size variability during the current interglacial and its provenance in the innermost part of the East Antarctic plateau as well as in peripheral regions located close to the Transantarctic Mountains. The local importance of aeolian mineral dust aerosol deflated from low-elevation areas of peripheral East Antarctica is also discussed in the light of new data from several coastal, low-elevation sites.
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| 28. |
- Ehn, Maria, et al.
(author)
-
Users perspectives on interactive distance technology enabling home-based motor training for stroke patients
- 2015
-
In: Stud. Health Technol. Informatics. - : IOS Press. - 9781614995159 ; , s. 145-152
-
Conference paper (peer-reviewed)abstract
- The aim of this work has been to develop a technical support enabling home-based motor training after stroke. The basis for the work plan has been to develop an interactive technical solution supporting three different groups of stroke patients: (1) patients with stroke discharged from hospital with support from neuro team; (2) patients with stroke whose support from neuro team will be phased out and (3) patients living with impaired motor functions long-term. The technology has been developed in close collaboration with end-users using a method earlier evaluated and described [12]. This paper describes the main functions of the developed technology. Further, results from early user-tests with end-users, performed to identify needs for improvements to be carried out during further technical development. The developed technology will be tested further in a pilot study of the safety and, usefulness of the technology when applied as a support for motor training in three different phases of the post-stroke rehabilitation process.
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| 29. |
- Ekvall Hansson, Eva, et al.
(author)
-
Quality of Research Projects in Medical Education – Does Extended Time Lead to Higher Quality?
- 2015
-
In: Education. - 2162-9463. ; 5:1, s. 20-25
-
Journal article (peer-reviewed)abstract
- The research projects produced in higher education are important not only for developing skills in critical appraisal in order to give students tools for working evidence-based but also as a measure of quality of higher education. When the Bologna Process was implemented at Lund University in Sweden, the courses in research projects were extended and are now performed at the basic level as well as the advanced level in the program, in the form of one bachelor thesis in the middle of the program and one master thesis at the end of the program. The aim of this study was to analyze whether the extension of the research project course in the medical program at a Swedish university had affected the quality of the research projects in the course. One teacher read all of the papers from the students on the extended 20-week course and the previous 10-week course. During the reading of the papers, scoring rubrics were used to grade the papers. A comparison between the two courses was made. The comparison showed that, in the items “title,” “abstract,” “introduction,” “ethics” and in the total sum, the projects from the long course were given statistically significantly higher grading than the projects from the short course. More projects from the long course passed the exam than the short course. We conclude that extended time seemed to improve quality of scientific writing in some of the items, but not all, and also resulted in more projects passing the exam. The item “ethics” is difficult for students to handle.
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| 30. |
- Ekvall-Hansson, Eva, et al.
(author)
-
Satisfaction with rehabilitation in relation to self-perceived quality of life and function among patients with stroke - a 12 month follow-up.
- 2013
-
In: Scandinavian Journal of Caring Sciences. - : Wiley. - 1471-6712 .- 0283-9318. ; 27:2, s. 373-379
-
Journal article (peer-reviewed)abstract
- Scand J Caring Sci; 2012 Satisfaction with rehabilitation in relation to self-perceived quality of life and function among patients with stroke - a 12 month follow-up Background and Purpose: Stroke causes complex disability and function, and perceived quality of life has been shown to correlate with satisfaction with care as well as with life in general among stroke patients. The aim of this study was to study the relation of satisfaction with how rehabilitation was provided with self-perceived quality of life, self-perceived function and rehabilitation received, 12 months after the incidence. Method: The subjects were assessed 12 months after the onset of stroke. The Barthel index was used to measure function, and the EuroQol-5D to measure quality of life. To measure satisfaction with how rehabilitation was provided, a questionnaire from the Swedish Stroke Register was used. Results: Two hundred and eighty-three patients participated in the follow-up, 137 women and 146 men, aged between 42 and 95 years (mean age 75.2, SD 11.8). For the majority of patients rehabilitation was initiated at in-hospital care (directly after onset). One hundred and sixty-eight patients considered that rehabilitation was well provided for. Sixty-six regarded that the rehabilitation was only partly provided for and 35 that it was not provided for at all. High value on Barthel Index was associated with satisfaction with how rehabilitation was provided for (OR 2.81). Also, rehabilitation on three or more levels was negatively associated with satisfaction with rehabilitation provision (OR 0.24) and so was being male (OR 0.49). Conclusion: In this study, patients with higher values on Barthel Index were more satisfied with how rehabilitation was provided for. However, male patients and patients who received rehabilitation on three or more levels of care were less satisfied. Given the assumption that patients with more severe dysfunction after stroke are being rehabilitated on more levels, this might imply that it is not the amount of rehabilitation that gives satisfaction but the patients self-perceived function after rehabilitation.
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| 31. |
- Ekvall-Hansson, Eva, et al.
(author)
-
Stroke and unsteadiness - A cross-sectional study from primary health care.
- 2014
-
In: NeuroRehabilitation. - 1878-6448. ; 34:2, s. 221-226
-
Journal article (peer-reviewed)abstract
- Dizziness is seldom the only symptom among patients who develop stroke but patients, hospitalized for vertigo are at higher risk of stroke than the general population. The proportions of patients who have remaining dizziness after a stroke seem to be unclear.
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| 32. |
- Elam, Katarina, et al.
(author)
-
Educating Responsible Citizens; Intercultural Competence and Aesthetic Education
- 2017
-
In: Learning Scenarios for Social and Cultural Change: Bildung Through Academic Teaching.. - : Peter Lang. - 9783631729304
-
Book chapter (peer-reviewed)abstract
- The article is a joint product of researchers working within different disciplines and with different kinds of knowledge interests, but united by a common interest in the question of how aesthetic education can lead to intercultural competence and education of responsible citizens. What characterizes aesthetic education and how can a clarification of pedagogical tools of such education help us clarify intercultural competence as a learning goal? What are the connections between intercultural education and aesthetic education and how can the latter contribute to the former? Our approach to these issues is a practical one. This means that our efforts are focused on a critical investigation of the conditions of the possibility of intercultural education. Our main argument in the article is that the core of intercultural competence is of a particular type, is active rather than passive and open to radically different experiences than our own. Having this starting point, we in the first step identify some tools through which intercultural competence and education can be made possible. The notions of aesthetic education and empathy are among these tools. Identifying these tools, we in the next step connect the identified tools to basic impediments in the way of intercultural education like that of obstacles for intercultural competence to take form like hidden prejudices of educators in order to remove them and clear the way for intercultural education. As a result of these two steps, educators engaged in, and pupils educated by intercultural education, become empowered. They are then enabled to clarify their hidden prejudices and counteract them instead of being steered by them. They also become empathetic and “responsible citizens”.
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| 33. |
- Erhardt, Tobias, et al.
(author)
-
High-resolution aerosol concentration data from the Greenland NorthGRIP and NEEM deep ice cores
- 2022
-
In: Earth System Science Data. - : Copernicus GmbH. - 1866-3508 .- 1866-3516. ; 14:3, s. 1215-1231
-
Journal article (peer-reviewed)abstract
- Records of chemical impurities from ice cores enable us to reconstruct the past deposition of aerosols onto polar ice sheets and alpine glaciers. Through this they allow us to gain insight into changes of the source, transport and deposition processes that ultimately determine the deposition flux at the coring location. However, the low concentrations of the aerosol species in the ice and the resulting high risk of contamination pose a formidable analytical challenge, especially if long, continuous and highly resolved records are needed. Continuous flow analysis, CFA, the continuous melting, decontamination and analysis of ice-core samples has mostly overcome this issue and has quickly become the de facto standard to obtain high-resolution aerosol records from ice cores after its inception at the University of Bern in the mid-1990s.Here, we present continuous records of calcium (Ca2+), sodium (Na+), ammonium (NH+4), nitrate (NO-3) and electrolytic conductivity at 1 mm depth resolution from the NGRIP (North Greenland Ice Core Project) and NEEM (North Greenland Eemian Ice Drilling) ice cores produced by the Bern Continuous Flow Analysis group in the years 2000 to 2011 (Erhardt et al., 2021). Both of the records were previously used in a number of studies but were never published in full 1 mm resolution. Alongside the 1 mm datasets we provide decadal averages, a detailed description of the methods, relevant references, an assessment of the quality of the data and its usable resolution. Along the way we will also give some historical context on the development of the Bern CFA system.
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| 34. |
- Eriksson, Hanna, et al.
(author)
-
Interobserver Variability of Histopathological Prognostic Parameters in Cutaneous Malignant Melanoma : Impact on Patient Management
- 2013
-
In: Acta Dermato-Venereologica. - : Medical Journals Sweden AB. - 0001-5555 .- 1651-2057. ; 93:4, s. 411-416
-
Journal article (peer-reviewed)abstract
- Clinical management of primary cutaneous melanomas is based on histopathological staging of the tumour. The aim of this study was to investigate, in a non-selected population in clinical practice, the agreement rate between general pathologists and pathologists experienced in melanoma in terms of the evaluation of histopathological prognostic parameters in cutaneous malignant melanomas, and to what extent the putative variability affected clinical management. A total of 234 cases of invasive cutaneous malignant melanoma were included in the study from the Stockholm-Gotland Healthcare Region in Sweden. Overall interobserver variability between a general pathologist and an expert review was 68.8-84.8%. Approximately 15.5% of melanomas <= 1 mm were re-classified either as melanoma in situ or melanomas >1 mm after review. In conclusion, review by a pathologist experienced in melanoma resulted in a change in recommendations about surgical excision margins and/or sentinel node biopsy in subgroups of Ti melanomas.
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| 35. |
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| 36. |
- Eriksson, Hanna, et al.
(author)
-
Low level of education is associated with later stage at diagnosis and reduced survival in cutaneous malignant melanoma : A nationwide population-based study in Sweden
- 2013
-
In: European Journal of Cancer. - Oxford : Elsevier. - 0959-8049 .- 1879-0852. ; 49:12, s. 2705-2716
-
Journal article (peer-reviewed)abstract
- BACKGROUND:A worse outcome has been reported for cutaneous malignant melanoma (CMM) patients with low socioeconomic status. We have investigated the association between level of education, clinical stage at diagnosis (stage at diagnosis) and CMM-specific survival in Sweden.METHODS:We identified 27,235 patients from the Swedish Melanoma Register diagnosed with a primary invasive CMM between 1990 and 2007 and linked data to nationwide, population-based, health and census registers with a follow-up to 2010.RESULTS:The odds ratio (OR) of higher disease stage at diagnosis was significantly increased in lower education groups (OR stage II versus I=1.6; 95% confidence interval (CI)=1.5-1.7. OR stage III-IV versus I=2.3; 95% CI=1.8-2.9). The risk of dying of CMM, was significantly increased in patients with low (hazard ratio (HR) low versus high=2.02; 95% CI=1.80-2.26; p<0.0001) and intermediate (HR intermediate versus high=1.35; 95% CI=1.20-1.51; p<0.0001) level of education. After adjustment for age, gender, stage at diagnosis and other known prognostic factors, the HRs remained significant for low versus high (HR=1.13; 95% CI=1.01-1.27; p=0.04) but not for intermediate versus high (HR=1.11; 95% CI=0.99-1.24; p=0.08) education. The HR associated with low level of education was significantly higher among female patients, patients <55years, patients with truncal tumours and during the first 5years after diagnosis.CONCLUSION:Lower level of education is associated with reduced CMM-specific survival, which may at least partially be attributed to a more advanced stage at diagnosis. These results emphasise the need for improved early detection strategies.
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| 37. |
- Ferreira, Duarte M. S., et al.
(author)
-
LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force
- 2019
-
In: Skeletal Muscle. - : BioMed Central. - 2044-5040. ; 9:1
-
Journal article (peer-reviewed)abstract
- Background: Skeletal muscle mass and strength are crucial determinants of health. Muscle mass loss is associated with weakness, fatigue, and insulin resistance. In fact, it is predicted that controlling muscle atrophy can reduce morbidity and mortality associated with diseases such as cancer cachexia and sarcopenia.Methods: We analyzed gene expression data from muscle of mice or human patients with diverse muscle pathologies and identified LMCD1 as a gene strongly associated with skeletal muscle function. We transiently expressed or silenced LMCD1 in mouse gastrocnemius muscle or in mouse primary muscle cells and determined muscle/cell size, targeted gene expression, kinase activity with kinase arrays, protein immunoblotting, and protein synthesis levels. To evaluate force, calcium handling, and fatigue, we transduced the flexor digitorum brevis muscle with a LMCD1-expressing adenovirus and measured specific force and sarcoplasmic reticulum Ca2+ release in individual fibers. Finally, to explore the relationship between LMCD1 and calcineurin, we ectopically expressed Lmcd1 in the gastrocnemius muscle and treated those mice with cyclosporine A (calcineurin inhibitor). In addition, we used a luciferase reporter construct containing the myoregulin gene promoter to confirm the role of a LMCD1-calcineurin-myoregulin axis in skeletal muscle mass control and calcium handling.Results: Here, we identify LIM and cysteine-rich domains 1 (LMCD1) as a positive regulator of muscle mass, that increases muscle protein synthesis and fiber size. LMCD1 expression in vivo was sufficient to increase specific force with lower requirement for calcium handling and to reduce muscle fatigue. Conversely, silencing LMCD1 expression impairs calcium handling and force, and induces muscle fatigue without overt atrophy. The actions of LMCD1 were dependent on calcineurin, as its inhibition using cyclosporine A reverted the observed hypertrophic phenotype. Finally, we determined that LMCD1 represses the expression of myoregulin, a known negative regulator of muscle performance. Interestingly, we observed that skeletal muscle LMCD1 expression is reduced in patients with skeletal muscle disease.Conclusions: Our gain- and loss-of-function studies show that LMCD1 controls protein synthesis, muscle fiber size, specific force, Ca2+ handling, and fatigue resistance. This work uncovers a novel role for LMCD1 in the regulation of skeletal muscle mass and function with potential therapeutic implications.
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| 38. |
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| 39. |
- Fischer, Hubertus, et al.
(author)
-
Reconstruction of millennial changes in dust emission, transport and regional sea ice coverage using the deep EPICA ice cores from the Atlantic and Indian Ocean sector of Antarctica
- 2007
-
In: Earth and Planetary Science Letters. - : Elsevier BV. - 0012-821X. ; 260, s. 340-354
-
Journal article (peer-reviewed)abstract
- Continuous sea salt and mineral dust aerosol records have been studied on the two EPICA (European Project for Ice Coring inAntarctica) deep ice cores. The joint use of these records from opposite sides of the East Antarctic plateau allows for an estimate ofchanges in dust transport and emission intensity as well as for the identification of regional differences in the sea salt aerosolsource. The mineral dust flux records at both sites show a strong coherency over the last 150 kyr related to dust emission changes inthe glacial Patagonian dust source with three times higher dust fluxes in the Atlantic compared to the Indian Ocean sector of theSouthern Ocean (SO). Using a simple conceptual transport model this indicates that transport can explain only 40% of theatmospheric dust concentration changes in Antarctica, while factor 5–10 changes occurred. Accordingly, the main cause for the strong glacial dust flux changes in Antarctica must lie in environmental changes in Patagonia. Dust emissions, hence environmentalconditions in Patagonia, were very similar during the last two glacials and interglacials, respectively, despite 2–4 °C warmertemperatures recorded in Antarctica during the penultimate interglacial than today. 2–3 times higher sea salt fluxes found in bothice cores in the glacial compared to the Holocene are difficult to reconcile with a largely unchanged transport intensity and thedistant open ocean source. The substantial glacial enhancements in sea salt aerosol fluxes can be readily explained assuming sea iceformation as the main sea salt aerosol source with a significantly larger expansion of (summer) sea ice in the Weddell Sea than inthe Indian Ocean sector. During the penultimate interglacial, our sea salt records point to a 50% reduction of winter sea icecoverage compared to the Holocene both in the Indian and Atlantic Ocean sector of the SO. However, from 20 to 80 ka beforepresent sea salt fluxes show only very subdued millennial changes despite pronounced temperature fluctuations, likely due to thelarge distance of the sea ice salt source to our drill sites.
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| 40. |
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| 41. |
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| 42. |
- Hansson, Klas, 1944-, et al.
(author)
-
Bakom bilderna : Biskopsporträtt i Strängnäs
- 2019. - 1
-
Book (pop. science, debate, etc.)abstract
- Sedan reformationstiden finns en serie porträtt av Strängnäs stifts biskopar. De flesta hänger i domkapitelshuset, ett par i biskopsgården och de är inte lätta att få se. Men i denna bok visas de alla, från Petrus Jonæ till Hans-Erik Nordin. Vilka var då dessa män bakom bilderna? Alla biskopar sedan reformationen ges i denna bok en presentation; deras bakgrund, inriktning och biskopsgärning skildras. I en övergripande artikel sätts denna porträttkonst också in i sitt sammanhang. Stav, biskopsmössa och kors är tre av biskoparnas insignier. Strängnäsbiskoparnas kåpor, stavar och biskopsringar liksom biskopsstolen i domkyrkan skildras i text och bild, allt från biskop Rogges medeltida kåpa till dagens enkla resekåpor. Bakom bilderna har utarbetats inom Strängnäs stifts herdaminneskommitté och är författad av professor Ingun Montgomery, teol. dr. Jarl Jergmar, teol. dr. Fredrik Santell, prosten Karin Karlberg, fil. dr. Margareta Nisser Dalman och docent Klas Hansson, som också varit bokens redaktör.
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| 43. |
- Hansson, Karin M, et al.
(author)
-
Cysteine-rich secretory proteins in snake venoms form high affinity complexes with human and porcine beta-microseminoproteins.
- 2009
-
In: Toxicon. - : Elsevier BV. - 0041-0101. ; 54, s. 128-137
-
Journal article (peer-reviewed)abstract
- beta-Microseminoprotein (MSP), a 10kDa protein in human seminal plasma, binds human cysteine-rich secretory protein-3 (CRISP-3) with high affinity. CRISP-3 is a member of the family of CRISPs, which are widespread among animals. In this work we show that human as well as porcine MSP binds catrin, latisemin, pseudecin, and triflin, which are CRISPs present in the venoms of the snakes Crotalus atrox, Laticauda semifasciata, Pseudechis porphyriacus, and Trimeresurus flavoviridis, respectively. The CRISPs were purified from the venoms by affinity chromatography on a human MSP column and their identities were settled by gel electrophoresis and mass spectrometry. Their interactions with human and porcine MSPs were studied with size exclusion chromatography and surface plasmon resonance measurements. The binding affinities at 25 degrees C were between 10(-10)M and 10(-7)M for most of the interactions, with higher affinities for the interactions with porcine MSP compared to human MSP and with Elapidae CRISPs compared to Viperidae CRISPs. The high affinities of the bindings in spite of the differences in amino acid sequence between the MSPs as well as between the CRISPs indicate that the binding is tolerant to amino acid sequence variation and raise the question how universal this cross-species reaction between MSPs and CRISPs is.
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| 44. |
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| 45. |
- Hansson, Margareta, 1962-
(author)
-
Detecting changes in climate and atmospheric composition with tracers in Arctic ice caps
- 1993
-
Doctoral thesis (other academic/artistic)abstract
- Changes in climate and atmospheric composition over decades to a hundred thousand years have been studied by extracting records of various tracers from two Arctic ice cores. A seven metre long ice core of superimposed ice was recovered from the Storöya ice cap in north-eastern Svalbard. The annual increments of superimposed ice were identified by combining records of ice texture, ice structure, insoluble particle content and solid electrical conductivity. A net balance record over the time period A.D. 1954 to 1979 was established and the obtained information about past local climate is found to agree with observations. The chemical composition of the insoluble particles was examined but only limited information is gained about atmospheric aerosol composition due to the disturbed deposition record as is found in superimposed ice.The records from a 325 metre long surface-to-bedrock ice core from the Renland ice cap, East Greenland, cover a full glacial cycle into the previous interglacial Eem 130 000 years B.P. Changes in climate are revealed by the record of stable oxygen isotopes. Fast and large variations in temperature between glacial and interglacial periods, but also in mid and late parts of the last glaciation, are found in agreement with other Greenland deep ice cores. The precipitation rate is found to vary significantly between different climatic regimes. Comparison with records from Antarctica suggests a roughly parallel climatic development in the two hemispheres. Changes in the composition of the atmospheric aerosol have been studied by extracting the first Northern Hemisphere record of major anions, major cations, insoluble dust and acidity over a full climatic cycle. The concentration in the ice of most impurities is higher in cold glacial stages. However, for impurities with a strong biogenic component (nitrate, ammonium and methanesulphonate) the concentration is lower in cold glacial stages which is opposite to Southern Hemisphere records. The ammonium record has been utilised to discuss source areas of the greenhouse gas methane. High ammonium concentrations in mild glacial stages are found to coincide with high global concentrations of methane, which points to the terrestrial biosphere at high northern latitudes as a possible source. A simple model simulation indicates that concentration changes in the ice of one order of magnitude between different climatic regimes can be explained entirely by changes in the hydrological cycle and the general circulation of the atmosphere. These physical changes of the atmosphere affects the radiation balance of the atmosphere, just as changes in source emissions, by strongly changing the airborne concentration and composition of the atmospheric aerosol.
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| 46. |
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| 47. |
- Hörnquist, J. O., et al.
(author)
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Repeated short-term sick-leave and quality of life : An evaluation of a clinical socio-medical intervention
- 1990
-
In: Scandinavian Journal of Social Medicine. - : SAGE Publications. - 1403-4948 .- 0300-8037. ; 18:2, s. 91-95
-
Journal article (peer-reviewed)abstract
- The primary aim of this study was to evaluate a clinical socio-medical supportive program for repeated short-term sickleavers who exhibited no evident reason for their prolonged absence. Attention was drawn to changes in the quality of life of the participants. Ninety-nine persons took part in the full program. The sex distribution was even and the mean age was 32 years. The average number of days of sick-leave during the year preceding the entrance into the program was 28. The most common self-stated diagnosis was upper respiratory infection or gastro-intestinal problems. The evaluation showed a significant change for the better in the quality of life and well-being of the patients, although more than every other patient did not explicitly attribute any personal benefit to the intervention itself. The results coincide irrespective of measuring method and, are by and large, consistent over most areas of life and components of well-being assessed. Thus the design and the results of the evalution look very promising concerning reliability, validity and especially sensitivity. A corresponding model may be applicable more generally when evaluating health- and medical care.
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| 48. |
- Iizuka, Yoshinori, et al.
(author)
-
Sulphate and chloride aerosols during Holocene and last glacial periods preserved in the Talos Dome Ice Core, a peripheral region of Antarctica
- 2013
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In: Tellus. Series B, Chemical and physical meteorology. - Stokcholm : Stockholm University Press. - 0280-6509 .- 1600-0889. ; 65, s. 20197-
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Journal article (peer-reviewed)abstract
- Antarctic ice cores preserve the record of past aerosols, an important proxy of past atmospheric chemistry. Here we present the aerosol compositions of sulphate and chloride particles in the Talos Dome (TD) ice core from the Holocene and Last Glacial Period. We find that the main salt types of both periods are NaCl, Na2SO4 and CaSO4, indicating that TD ice contains relatively abundant sea salt (NaCl) from marine primary particles. By evaluating the molar ratio of NaCl to Na2SO4, we show that about half of the sea salt does not undergo sulphatisation during late Holocene. Compared to in inland Antarctica, the lower sulphatisation rate at TD is probably due to relatively little contact between sea salt and sulphuric acid. This low contact rate can be related to a reduced time of reaction for marine-sourced aerosol before reaching TD and/or to a reduced post-depositional effect from the higher accumulation rate at TD. Many sulphate and chloride salts are adhered to silicate minerals. The ratio of sulphate-adhered mineral to particle mass and the corresponding ratio of chloride-adhered mineral both increase with increasing dust concentration. Also, the TD ice appears to contain Ca(NO3)(2) or CaCO3 particles, thus differing from aerosol compositions in inland Antarctica, and indicating the proximity of peripheral regions to marine aerosols.
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| 49. |
- Iizuka, Yoshinori, et al.
(author)
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The rates of sea salt sulfatization in the atmosphere and surface snow of inland Antarctica
- 2012
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In: Journal of Geophysical Research. - 0148-0227 .- 2156-2202. ; 117, s. D04308-
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Journal article (peer-reviewed)abstract
- Most of the aerosol particles present in the surface snow and ice of inland Antarctica come from primary sea salt (sodium chloride) and marine biological activity (methansulfonic and sulfuric acids). Melted water from surface snow, firn, and Holocene ice contains mainly sodium, chloride, and sulfate ions. Although it is well known that sea salt aerosols react rapidly with sulfuric acid, a process known as sulfatization, it is not known when this process takes place. In this research we undertake to measure the proportion of sea salt aerosols that undergo sulfatization in the atmosphere and surface snow, as opposed to deeper ice, in order to understand the suitability of sea salt aerosols as a proxy for past climates in deep ice cores. We directly measure the sulfatization rates in recently fallen snow (0-4 m in depth) collected at the Dome Fuji station, using X-ray dispersion spectroscopy to determine the constituent elements of soluble particles and computing the molar ratios of sodium chloride and sodium sulfate. We estimate that about 90% of the initial sea salt aerosols sulfatize as they are taken up by precipitation over Dome Fuji or in the snowpack within one year after being deposited on the ice sheet.
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| 50. |
- Ingvander, Susanne, et al.
(author)
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Snow particle sizes and their distributions in Dronning Maud Land, Antarctica, at sample, local and regional scales
- 2016
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In: Antarctic Science. - 0954-1020 .- 1365-2079. ; 28:3, s. 219-231
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Journal article (peer-reviewed)abstract
- In this study, snow particle size variability was investigated along a transect in Dronning Maud Land from the coast to the polar plateau. The aim of the study was to better understand the spatial and temporal variations in surface snow properties. Samples were collected twice daily during a traverse in 2007-08 to capture regional variability. Local variability was assessed by sampling in 10 x 10m grids (5m spacing) at selected locations. The particle size and shape distributions for each site were analysed through digital image analysis. Snow particle size variability is complex at different scales, and shows an internal variability of 0.18-3.31 mm depending on the sample type (surface, grid or pit). Relationships were verified between particle size and both elevation and distance to the coast (moisture source). Regional seasonal changes were also identified, particularly on the lower elevations of the polar plateau. This dataset may be used to quantitatively analyse the optical properties of surface snow for remote sensing. The details of the spatial and temporal variations observed in our data provide a basis for further studies of the complex and coupled processes affecting snow particle size and the interpretation of remote sensing of snow covered areas.
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