| 1. |
- Austeng, Dordi, et al.
(author)
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Incidence of and risk factors for neonatal morbidity after active perinatal care : extremely preterm infants study in Sweden (EXPRESS)
- 2010
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In: Acta Paediatrica. - : Wiley. - 0803-5253 .- 1651-2227. ; 99:7, s. 978-992
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Journal article (peer-reviewed)abstract
- Aims: The aim of this study was to determine the incidence of neonatal morbidity in extremely preterm infants and to identify associated risk factors. Methods: Population based study of infants born before 27 gestational weeks and admitted for neonatal intensive care in Sweden during 2004-2007. Results: Of 638 admitted infants, 141 died. Among these, life support was withdrawn in 55 infants because of anticipation of poor long-term outcome. Of 497 surviving infants, 10% developed severe intraventricular haemorrhage (IVH), 5.7% cystic periventricular leucomalacia (cPVL), 41% septicaemia and 5.8% necrotizing enterocolitis (NEC); 61% had patent ductus arteriosus (PDA) and 34% developed retinopathy of prematurity (ROP) stage >= 3. Eighty-five per cent needed mechanical ventilation and 25% developed severe bronchopulmonary dysplasia (BPD). Forty-seven per cent survived to one year of age without any severe IVH, cPVL, severe ROP, severe BPD or NEC. Tocolysis increased and prolonged mechanical ventilation decreased the chances of survival without these morbidities. Maternal smoking and higher gestational duration were associated with lower risk of severe ROP, whereas PDA and poor growth increased this risk. Conclusion: Half of the infants surviving extremely preterm birth suffered from severe neonatal morbidities. Studies on how to reduce these morbidities and on the long-term health of survivors are warranted.
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| 2. |
- Adamaki, Angeliki, et al.
(author)
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ENVRI-FAIR Project brief on implementation of Open Science and EOSC targets
- 2021
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Other publication (other academic/artistic)abstract
- In the ENVRI-FAIR project brief on implementation of Open Science and EOSC targets the current achievements and planned activities in ENVRI-FAIR are summarised with regard to a) Integration with the EOSC infrastructure b) FAIR principles implementation and repositories c) Technical, semantic, legal and organisational interoperability d) Stewardship of data and e) Cross-cluster collaboration activities and achievements.
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| 3. |
- Ahlström, Isabell, et al.
(author)
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Reliability of the Swedish version of the Exercise Self-Efficacy Scale (S-ESES) : a test-retest study in adults with neurological disease
- 2015
-
In: Physiotherapy Theory and Practice. - : Informa UK Limited. - 0959-3985 .- 1532-5040. ; 31:3, s. 194-199
-
Journal article (peer-reviewed)abstract
- Objective: To examine the test-retest reliability of the Swedish translated version of the Exercise Self-Efficacy Scale (S-ESES) in people with neurological disease and to examine internal consistency. Design: Test-retest study.Subjects: A total of 30 adults with neurological diseases including: Parkinson's disease; Multiple Sclerosis; Cervical Dystonia; and Charcot Marie Tooth disease.Method: The S-ESES was sent twice by surface mail. Completion interval mean was 16 days apart. Weighted kappa, intraclass correlation coefficient 2,1 [ICC (2,1)], standard error of measurement (SEM), also expressed as a percentage value (SEM%), and Cronbach's alpha were calculated.Results: The relative reliability of the test-retest results showed substantial agreement measured using weighted kappa (MD = 0.62) and a very high-reliability ICC (2,1) (0.92). Absolute reliability measured using SEM was 5.3 and SEM% was 20.7. Excellent internal consistency was shown, with an alpha coefficient of 0.91 (test 1) and 0.93 (test 2).Conclusion: The S-ESES is recommended for use in research and in clinical work for people with neurological diseases. The low-absolute reliability, however, indicates a limited ability to measure changes on an individual level.
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| 4. |
- Al Musawi, Ahmed, et al.
(author)
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Intervention for a correct medication list and medication use in older adults : a non-randomised feasibility study among inpatients and residents during care transitions
- 2024
-
In: International Journal of Clinical Pharmacy. - : Springer. - 2210-7703 .- 2210-7711. ; 46, s. 639-647
-
Journal article (peer-reviewed)abstract
- BackgroundMedication discrepancies in care transitions and medication non-adherence are problematic. Few interventions consider the entire process, from the hospital to the patient's medication use at home.AimIn preparation for randomised controlled trials (RCTs), this study aimed (1) to investigate the feasibility of recruitment and retention of patients, and data collection to reduce medication discrepancies at discharge and improve medication adherence, and (2) to explore the outcomes of the interventions.MethodParticipants were recruited from a hospital and a residential area. Hospital patients participated in a pharmacist-led intervention to establish a correct medication list upon discharge and a follow-up interview two weeks post-discharge. All participants received a person-centred adherence intervention for three to six months. Discrepancies in the medication lists, the Beliefs about Medicines Questionnaire (BMQ-S), and the Medication Adherence Report Scale (MARS-5) were assessed.ResultsOf 87 asked to participate, 35 were included, and 12 completed the study. Identifying discrepancies, discussing discrepancies with physicians, and performing follow-up interviews were possible. Conducting the adherence intervention was also possible using individual health plans for medication use. Among the seven hospital patients, 24 discrepancies were found. Discharging physicians agreed that all discrepancies were errors, but only ten were corrected in the discharge information. Ten participants decreased their total BMQ-S concern scores, and seven increased their total MARS-5 scores.ConclusionBased on this study, conducting the two RCTs separately may increase the inclusion rate. Data collection was feasible. Both interventions were feasible in many aspects but need to be optimised in upcoming RCTs.
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| 5. |
- Alfvén, Tobias, et al.
(author)
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Low-level cadmium exposure and osteoporosis.
- 2000
-
In: Journal of Bone and Mineral Research. - 0884-0431 .- 1523-4681. ; 15, s. 1579-1586
-
Journal article (peer-reviewed)abstract
- Osteoporosis is a major cause of morbidity worldwide. A number of risk factors, such as age and gender, are well established. High cadmium exposure causes renal damage and in severe cases also causes osteoporosis and osteomalacia, We have examined whether long-term Pow-level cadmium exposure increases the risk of osteoporosis. Bone mineral density (BMD) in the forearm was measured in 520 men and 544 women, aged 16-81 years, environmentally or occupationally exposed to cadmium, using dual-energy X-ray absorptiometry (DXA) technique. Cadmium in urine was used as the dose estimate and protein HC was used: as a marker of renal tubular damage. There was a clear dose-response relation between cadmium dose and the prevalence of tubular proteinuria. Inverse relations were found between cadmium dose, tubular proteinuria, and BMD, particularly apparent in persons over 60 years of age, There was a dose-response relation between cadmium dose and osteoporosis. The odds ratios (ORs) for men were 2.2 (95% CI, 1.0-4.8) in the dose group 0.5-3 nmol Cd/mmol creatinine and 5.3 (2.0-14) in the highest dose category (greater than or equal to 3 nmol/mmol creatinine) compared with the lowest dose group (<0.5 nmol Cd/mmol creatinine). For women, the OR was 1.8 (0.65-5.3) in the dose group 0.53 nmol Cd/mmol creatinine. We conclude that exposure to low levels of cadmium is associated with an increased risk of osteoporosis.
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| 6. |
- Anens, Elisabeth, et al.
(author)
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Exploratory Study of Physical Activity in Persons With Charcot-Marie-Tooth Disease
- 2015
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In: Archives of Physical Medicine and Rehabilitation. - : Elsevier BV. - 0003-9993 .- 1532-821X. ; 96:2, s. 260-268
-
Journal article (peer-reviewed)abstract
- Objectives: To explore and describe the perceived facilitators and barriers to physical activity, and to examine the physical activity correlates in people with Charcot-Marie-Tooth (CMT) disease. Design: Cross-sectional survey study. Setting: Community-living subjects. Participants: Swedish people with CMT disease (N=44; men, 54.5%; median age, 59.5y [interquartile range, 45.3-64.8y]). Interventions: Not applicable. Main Outcome Measures: The survey included open-ended questions and standardized self-reported scales measuring physical activity, fatigue, activity limitation, self-efficacy for physical activity, fall-related self-efficacy, social support, and enjoyment of physical activity. Physical activity was measured by the Physical Activity Disability Survey-Revised. Results: Qualitative content analysis revealed that personal factors such as fatigue, poor balance, muscle weakness, and pain were important barriers for physical activity behavior. Facilitators of physical activity were self-efficacy for physical activity, activity-related factors, and assistive devices. Multiple regression analysis showed that self-efficacy for physical activity (beta=.41) and fatigue (beta=-.30) explained 31.8% of the variation in physical activity (F-2,F-40=10.78, P=.000). Conclusions: Despite the well-known benefits of physical activity, physical activity in people with CMT disease is very sparsely studied. These new results contribute to the understanding of factors important for physical activity behavior in people with CMT disease and can guide health professionals to facilitate physical activity behavior in this group of patients. (C) 2015 by the American Congress of Rehabilitation Medicine
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| 7. |
- Anens, Elisabeth, et al.
(author)
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Physical activity in subjects with multiple sclerosis with focus on gender differences : a survey
- 2014
-
In: BMC Neurology. - : Springer Science and Business Media LLC. - 1471-2377. ; 14, s. 47-
-
Journal article (peer-reviewed)abstract
- Background: There is increasing research that examines gender-issues in multiple sclerosis (MS), but little focus has been placed on gender-issues regarding physical activity. The aim of the present study was to describe levels of physical activity, self-efficacy for physical activity, fall-related self-efficacy, social support for physical activity, fatigue levels and the impact of MS on daily life, in addition to investigating gender differences. Methods: The sample for this cross-sectional cohort study consisted of 287 (84 men; 29.3%) adults with MS recruited from the Swedish Multiple Sclerosis Registry. A questionnaire was sent to the subjects consisting of the self-administrated measurements: Physical Activity Disability Survey - Revised, Exercise Self-Efficacy Scale, Falls-Efficacy Scale (Swedish version), Social Influences on Physical Activity, Fatigue Severity Scale and Multiple Sclerosis Impact Scale. Response rate was 58.2%. Results: Men were less physically active, had lower self-efficacy for physical activity and lower fall-related self-efficacy than women. This was explained by men being more physically affected by the disease. Men also received less social support for physical activity from family members. The level of fatigue and psychological consequences of the disease were similar between the genders in the total sample, but subgroups of women with moderate MS and relapsing remitting MS experienced more fatigue than men. Conclusions: Men were less physically active, probably a result of being more physically affected by the disease. Men being more physically affected explained most of the gender differences found in this study. However, the number of men in the subgroup analyses was small and more research is needed. A gender perspective should be considered in strategies for promoting physical activity in subjects with MS, e. g. men may need more support to be physically active.
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| 8. |
- Anens, Elisabeth, et al.
(author)
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Self-reported physical activity correlates in Swedish adults with multiple sclerosis : a cross-sectional study
- 2017
-
In: BMC Neurology. - : Springer Science and Business Media LLC. - 1471-2377. ; 17
-
Journal article (peer-reviewed)abstract
- Background: The benefits of physical activity in persons with Multiple Sclerosis (MS) are considerable. Knowledge about factors that correlate to physical activity is helpful in order to develop successful strategies to increase physical activity in persons with MS. Previous studies have focused on correlates to physical activity in MS, however falls self-efficacy, social support and enjoyment of physical activity are not much studied, as well as if the correlates differ with regard to disease severity. The aim of the study was to examine associations between physical activity and age, gender, employment, having children living at home, education, disease type, disease severity, fatigue, self-efficacy for physical activity, falls self-efficacy, social support and enjoyment of physical activity in a sample of persons with MS and in subgroups with regard to disease severity.Methods: This is a cross-sectional survey study including Swedish community living adults with MS, 287 persons, response rate 58.2%. The survey included standardized self-reported scales measuring physical activity, disease severity, fatigue, self-efficacy for physical activity, falls self-efficacy, and social support. Physical activity was measured by the Physical Activity Disability Survey – Revised.Results: Multiple regression analyzes showed that 59% (F(6,3)=64.9, p=0.000) of the variation in physical activity was explained by having less severe disease (β=-0.30), being employed (β=0.26), having high falls self-efficacy (β=0.20), having high self-efficacy for physical activity (β=0.17), and enjoying physical activity (β=0.11). In persons with moderate/severe MS, self-efficacy for physical activity explained physical activity.Conclusions: Consistent with previous research in persons with MS in other countries this study shows that disease severity, employment and self-efficacy for physical activity are important for physical activity. Additional important factors were falls self-efficacy and enjoyment. More research is needed to confirm this and the subgroup differences.
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| 9. |
- Anens, Elisabeth, et al.
(author)
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Validity and reliability of physical activity measures in multiple sclerosis
- 2023
-
In: Physiotherapy Theory and Practice. - : Taylor & Francis. - 0959-3985 .- 1532-5040. ; 39:1, s. 137-153
-
Journal article (peer-reviewed)abstract
- PURPOSE: The purpose was to evaluate the psychometric properties of physical activity measures in persons with multiple sclerosis (PwMS).METHODS: Adults with multiple sclerosis were recruited, n = 30 (validation) and n = 57 (test-retest). Steps measured with PiezoRX, Yamax SW200 and ActiGraph GT9X Link (AGlink) and time in different positions measured with AGlink were validated against data from video analysis. Psychometric properties of the Physical Activity and Disability Survey - Revised Swedish version (PADS-R(Sw)) was evaluated.RESULTS: The most valid measures were AGlink using the low-frequency extension filter, and PiezoRX with median absolute percentage errors (MeAPEs) of 0.9-3.1% and 1.3-3.3%. The MeAPEs were higher for Yamax SW200 (2.9-21.0%), AGlink display (3.6-44.8%) and AGlink normal filter (8.9-48.9%), indicating low validity. AGlink was not valid in measurements of sitting (MeAPE 12.0-12.5%) or lying (MeAPE 31.0-41.7%). The correlation between PADS-R(Sw) and AGlink steps was r = 0.492 (p = .009). The relative reliability of PADS-R(Sw) was ICC2,1 0.85 (CI 0.76-0.91), and absolute reliability was SEM 0.54.CONCLUSION: AGlink and PiezoRX were valid measures of steps in PwMS. The questionnaire PADS-R(Sw) was valid, with high relative reliability, but its absolute reliability was unsatisfactory.
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| 10. |
- Becker, F, et al.
(author)
-
Status of the RISING Project at GSI
- 2005
-
In: European Physical Journal A. Hadrons and Nuclei. - : Springer Science and Business Media LLC. - 1434-6001. ; 25:Suppl 1, s. 719-722
-
Journal article (peer-reviewed)abstract
- The FRS-RISING set-up at GSI uses secondary radioactive beams at relativistic energies for nuclear structure studies. At GSI the fragmentation or fission of stable primary beams up to U-238 provide secondary beams with sufficient intensity to perform gamma-ray spectroscopy. The RISING set-up is described and results of the first RISING campaign are presented. New experimental methods at relativistic energies are being investigated. Future experiments focus on state-of-the art nuclear structure physics covering exotic nuclei all over the nuclear chart.
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| 11. |
- Bengtsson, Jörgen, et al.
(author)
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The influence of age on the distribution of morphine and morphine-3-glucuronide across the blood-brain barrier in sheep
- 2009
-
In: British Journal of Pharmacology. - : Wiley. - 0007-1188 .- 1476-5381. ; 157:6, s. 1085-1096
-
Journal article (peer-reviewed)abstract
- Background and purpose The effect of age on the distribution of morphine and morphine-3-glucuronide (M3G) across the blood-brain barrier (BBB) was studied in a sheep model utilizing intracerebral microdialysis. The effect of neonatal asphyxia on brain drug distribution was also studied. Experimental approach Microdialysis probes were inserted into the cortex, striatum and blood of 11 lambs (127 gestation days) and six ewes. Morphine, 1 mg.kg(-1), was intravenously administered as a 10 min constant infusion. Microdialysis and blood samples were collected for up to 360 min and analysed using liquid chromatography-tandem mass spectrometry. The half-life, clearance, volume of distribution, unbound drug brain : blood distribution ratio (K(p,uu)) and unbound drug volume of distribution in brain (V(u,brain)) were estimated. Key results Morphine K(p,uu) was 1.19 and 1.89 for the sheep and premature lambs, respectively, indicating that active influx into the brain decreases with age. Induced asphyxia did not affect transport of morphine or M3G across the BBB. Morphine V(u,brain) measurements were higher in sheep than in premature lambs. The M3G K(p,uu) values were 0.27 and 0.17 in sheep and premature lambs, indicating a net efflux from the brain in both groups. Conclusions and implications The morphine K(p,uu) was above unity, indicating active transport into the brain; influx was significantly higher in premature lambs than in adult sheep. These results in sheep differ from those in humans, rats, mice and pigs where a net efflux of morphine from the brain is observed.
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| 12. |
- Bourelius, Lars, et al.
(author)
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Öppna digitala resurser (OER)
- 2012
-
In: Nyheter & Debatt. - 1651-3363. ; :3, s. 4-4
-
Journal article (other academic/artistic)abstract
- Lärande sker i sociala sammanhang. Genom nätet är klassrummet idag globalt. Tusentals universitet, skolor och lärare i världen delar idag med sig av kursmaterial, föreläsningar, experiment, reportage och bilder så att andra kan återanvända materialet i sin undervisning.
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| 13. |
- Caamano, M, et al.
(author)
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Isomers in neutron-rich A approximate to 190 nuclides from Pb-208 fragmentation
- 2005
-
In: European Physical Journal A. Hadrons and Nuclei. - : Springer Science and Business Media LLC. - 1434-6001. ; 23:2, s. 201-215
-
Journal article (peer-reviewed)abstract
- Relativistic projectile fragmentation of Pb-208 has been used to produce isomers in neutron-rich, A approximate to 190 nuclides. A forward-focusing spectrometer provided ion-by-ion mass and charge identification. The detection of gamma-rays emitted by stopped ions has led to the assignment of isomers in Ta-188, W-190, Re-192, Re-193, Os-195, Ir-197, Ir-198, Pt-200, Pt-201, Pt-202 and Au-203, with half-lives ranging from approximately 10 ns to 1 ms. Tentative isomer information has been found also for Er-174, Er-175, Hf-185, Re-191, Re-194 and Ir-199. In most cases, time-correlated, singles gamma-ray events provided the first spectroscopic data on excited states for each nuclide. In Pt-200 and Pt-201. the assignments are supported by gamma-gamma coincidences. Isomeric ratios provide additional information, such as half-life and transition energy constraints in particular cases. The level structures of the platinum isotopes are discussed, and comparisons are made with isomer systematics.
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| 14. |
- Caceres, L., et al.
(author)
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Spherical proton-neutron structure of isomeric states in Cd-128
- 2009
-
In: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 79:1, s. 011301-
-
Journal article (peer-reviewed)abstract
- The gamma-ray decay of isomeric states in the even-even nucleus Cd-128 has been observed. The nucleus of interest was produced both by the fragmentation of Xe-136 and the fission of U-238 primary beams. The level scheme was unambiguously constructed based on.. coincidence relations in conjunction with detailed lifetime analysis employed for the first time on this nucleus. Large-scale shell-model calculations, without consideration of excitations across the N = 82 shell closure, were performed and provide a consistent description of the experimental level scheme. The structure of the isomeric states and their decays exhibit coexistence of proton, neutron, and strongly mixed configurations due to p. interaction in overlapping orbitals for both proton and neutron holes.
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| 15. |
- Djureinovic, Dijana, et al.
(author)
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Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer
- 2018
-
In: Lung Cancer. - : Elsevier BV. - 0169-5002 .- 1872-8332. ; 125, s. 157-163
-
Journal article (peer-reviewed)abstract
- Cancer testis antigens (CTAs) are defined as proteins that are specifically expressed in testis or placenta and their expression is frequently activated in cancer. Due to their ability to induce an immune response, CTAs may serve as suitable targets for immunotherapy. The aim of this study was to evaluate if there is reactivity against CTAs in the plasma of non-small cell lung cancer (NSCLC) patients through the detection of circulating antibodies. To comprehensively analyse auto-antibodies against CTAs the multiplexing capacities of suspension bead array technology was used. Bead arrays were created with 120 protein fragments, representing 112 CTAs. Reactivity profiles were measured in plasma samples from 133 NSCLC patients and 57 cases with benign lung diseases. Altogether reactivity against 69 antigens, representing 81 CTAs, was demonstrated in at least one of the analysed samples. Twenty-nine of the antigens (45 CTAs) demonstrated exclusive reactivity in NSCLC samples. Reactivity against CT47A genes, PAGE3, VCX, MAGEB1, LIN28B and C12orf54 were only found in NSCLC patients at a frequency of 1%-4%. The presence of autoantibodies towards these six antigens was confirmed in an independent group of 34 NSCLC patients.In conclusion, we identified autoantibodies against CTAs in the plasma of lung cancer patients. The reactivity pattern of autoantibodies was higher in cancer patients compared to the benign group, stable over time, but low in frequency of occurrence. The findings suggest that some CTAs are immunogenic and that these properties can be utilized as immune targets.
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| 16. |
- Donofrio, Claudio, et al.
(author)
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Long-term Reproducibility for Jupyter Notebook
- 2023
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Conference paper (peer-reviewed)abstract
- Computational notebooks (e.g. Jupyter notebook) are a popular choice for interactive scientific computing to convey descriptive information together with executable source code. The user can annotate the scientific development of the work, the methods applied, describe ancillary data or the analysis of results, with text, illustrations, figures, and equations. Such ‘executable’ documents provide a paradigm shift in scientific writing, where not only the science is described, but the actual computation and source code are openly available and can be reproduced and validated.Therefore, it is of paramount importance to preserve these documents. A unique and persistent identification (PID) is essential together with providing enough information to execute the source code. Generating a PID for a Jupyter notebook is not technically challenging. We can automatically collect system and run-time information and, with a guided workflow for the user, assemble a rich set of metadata. The collected information allows us to recreate the computational environment and run the source code, which in return (theoretically) should produce the same results as published.The importance of providing a rich set of metadata for all digital objects in a human readable and machine actionable form is well understood and widely accepted as necessity for reproducibility, traceability, and provenance. This is reflected in the FAIR principles (Wilkinson, https://doi.org/10.1038/sdata.2016.18) which are regarded as gold standard by many scientific communities.Pimentel et al. (https://doi.org/10.1109/MSR.2019.00077) analysed over 800’000 Jupyter notebooks from GitHub. 24 % executed without errors and only 4 % produced the same results. The likelihood to successfully compile and run a decade old source code is slim. Long term support for well established operating systems varies between 5 to 10 years, user software support is usually shorter and looking at free and open-source repositories there is often no support (or best effort) offered.We present an approach to safely reproduce the computational environment in the future with a focus on long-term availability. Instead of trying to reinstall the computational environment based on the stored metadata, we propose to archive the docker image, the user space (user installed packages) and finally the source code. Recreating the system in this way is more like restoring a backup, where backup is the equivalent of an entire computer system. It does not solve all the problems but removes a great deal of complexity and uncertainty.Though there are shortcomings in our approach, we believe our solution will lower the threshold for scientists to provide rich meta data, code and results attached to a publication that can be reproduced in the far future.
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| 17. |
- Doornenbal, P., et al.
(author)
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RISING: Gamma‐ray Spectroscopy with Radioactive Beams at GSI
- 2007
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In: AIP Conference Proceedings. - : AIP. - 0094-243X. - 9780735413283 ; 891, s. 99-107
-
Conference paper (peer-reviewed)abstract
- The Rare Isotope Spectroscopic INvestigation at GSI (RISING) project is a major pan‐European collaboration. Its physics aims are the studies of exotic nuclear matter with abnormal proton‐to‐neutron ratios compared with naturally occurring isotopes. RISING combines the FRagment Separator (FRS) which allows relativistic energies and projectile fragmentation reactions with EUROBALL Ge Cluster detectors for γ spectroscopic research. The RISING setup can be used in two different configurations. Either the nuclei of interest are investigated after being stopped or the heavy ions hit a secondary target at relativistic energies and the thereby occurring excitations are studied. For the latter case, MINIBALL Ge detectors and the HECTOR array are used in addition. Example achievements of the Fast Beam setup are presented and compared to various shell model calculations, while for the Stopped Beam setup initial results are shown.
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| 18. |
- Ericsson, M., et al.
(author)
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First medical contact in the pre-hospital phase of a myocardial infarction, the interaction between callers and tele-nurses impacts action and level of care
- 2018
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In: European Heart Journal. - : Oxford University Press. - 0195-668X .- 1522-9645. ; 39, s. 1120-1120
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Journal article (other academic/artistic)abstract
- Background: Pre-hospital delay in myocardial infarction (MI) patients' is of great concern. The total ischemic time, i.e., between symptom onset and reperfusion therapy is the most important factor to achieve best possible outcome. One reason for patient delay is choice of first medical Contact (FMC), still not everyone contact the emergency medical services. A previous Swedish cross-sectional multicentre study found that every fifth patient with an evolving ST elevated MI (STEMI) contacted an advisement tele-nurse intended for non-life-threatening situations as FMC. This caused a median difference in delay of 38 min from symptom onset to diagnosis. Advisement tele-nursing is an expanding actor in the Swedish healthcare system, as in some other Western nations.Purpose: The aim was to explore the communication between tele-nurses and callers when MI patients called a national health advisement number as FMC.Method: This study had a qualitative approach. We received access to 30 authentic calls. The recordings lasted between 0:39 minutes to 16:44 minutes, transcribed verbatim and analysed with content analysis. The following questions were applied to the transcript: (1) How do the callers communicate their symptom and context (2) How do the tele-nurses respond and which level of care was directed (3) Do the callers get an advice and what action do they take.Result: One third of the callers were female, aged 46–89 years, six were diagnosed with NSTEMI and 24 with STEMI. All tele-nurses were females. The calls followed a structure of three phases, opening-, orienting- and end-phase. The first phase was non-interfered, where the caller communicated their context and/or symptoms and tele-nurses adopt an active listening position, followed by two interactive phases. Four categories defined the interaction in the communication, indecisive, irrational, distinct or reasoning. The different interactions illustrated how tele-nurses and callers assessed and elaborated upon symptom, context and furthermore expressed the process in the dialogue. Type of interaction was pivotal for progress in the call and had impact on the communicative process either sufficient in reaching a mutual understanding or not. An indecisive or irrational interaction could increase risk of acute care not being recommended. A non explicit explanation, why it is of importance to seek acute care could lead caller to ignore the advice.Conclusion: Both communicative and medical skills are needed to identify level of urgency. Our study suggests that the interaction in the communication categorised in four types, indecisive, irrational or distinct or reasoning can mislead level of care directed as well as a disability to express the need of acute care. This knowledge adds new perspective and hopefully will our findings be useful to deepen our knowledge in identifying MI patients and in a broader sense improve educational efforts and diminsh delay.
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| 19. |
- Fellman, Vineta, et al.
(author)
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One-year survival of extremely preterm infants after active perinatal care in Sweden.
- 2009
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In: JAMA : the journal of the American Medical Association. - : American Medical Association (AMA). - 1538-3598 .- 0098-7484. ; 301:21, s. 2225-33
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Journal article (peer-reviewed)abstract
- Up-to-date information on infant survival after extremely preterm birth is needed for assessing perinatal care services, clinical guidelines, and parental counseling.
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| 20. |
- Gladnishki, KA, et al.
(author)
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Angular Momentum Population in the Projectile Fragmentation of 238U at 750 MeV/nucleon
- 2004
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In: Physical Review C (Nuclear Physics). - 0556-2813. ; 69:2
-
Journal article (peer-reviewed)abstract
- A systematic study of the population probabilities of nanosecond and microsecond isomers produced following the projectile fragmentation of U-238 at 750 MeV/nucleon has been undertaken at the SIS/FRS facility at GSI. Approximately 15 isomeric states in neutron-deficient nuclei around A similar to 190 were identified and the corresponding. isomeric ratios determined. The results are compared with a model based on the statistical abrasion-ablation description of relativistic fragmentation and simple assumptions concerning gamma cascades in the final nucleus (sharp cutoff). This model represents an upper limit for the population of isomeric states in relativistic projectile fragmentation. When the decay properties of the states above the isomer are taken into account, as opposed to the sharp cutoff approximation, a good agreement between the experimental and calculated angular momentum population is obtained.
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| 21. |
- Gorska, M., et al.
(author)
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Evolution of the N=82 Shell Gap below 132Sn Inferred from Core Excited States in 131In
- 2009
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In: Physics Letters. Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 672:4-5, s. 313-316
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Journal article (peer-reviewed)abstract
- The gamma-ray decay of ail excited state in In-131, the one proton hole neighbor of the doubly magic (132)sn has been measured. A high-spin, core-excited isomer with T-1/2 = 630(60) us was identified following production by both relativistic fragmentation of a Xe-136 beam and fission Of a U-238 beam. This state deexcites by a single gamma-ray branch of 3782(2) keV from which direct evidence for the size of the N = 82 shell gal) is inferred. The results are discussed in comparison to a shell-model Calculation including configurations across the closed shells at N = 82 and Z = 50. (C) 2009 Elsevier B.V. All rights reserved.
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| 22. |
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| 23. |
- Hellström, Karin, et al.
(author)
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Fear of falling, fall-related self-efficacy, anxiety and depression in individuals with chronic obstructive pulmonary disease
- 2009
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In: Clinical Rehabilitation. - : SAGE Publications. - 0269-2155 .- 1477-0873. ; 23:12, s. 1136-1144
-
Journal article (peer-reviewed)abstract
- OBJECTIVE: To examine the risk and frequency of falls, prevalence of fear of falling and activity avoidance, the magnitude of fall-related self-efficacy, and anxiety and depression in patients with chronic obstructive pulmonary disease. DESIGN AND SETTINGS: A cross-sectional study in patients with a diagnosis of chronic obstructive pulmonary disease who visited a lung clinic at a university hospital in Sweden. SUBJECTS: Successive inclusion from autumn 2005 to spring 2006 of 80 patients with a mean age of 65 years. INTERVENTION: Nil. MAIN MEASURES: A questionnaire about fall history and consequences of fall, The Falls Efficacy Scale, Swedish version, and the Hospital Anxiety and Depression Scale were used. RESULTS: Twenty patients (25%) reported at least one fall in the last year and 29% displayed fear of falling. Odds ratio for falling was 4-5 times higher in patients with severe chronic obstructive pulmonary disease. Older patients, women and patients with previous falls had a higher rate of fear of falling, and those with fear of falling had lower fall-related self-efficacy, increased level of anxiety and depression, more activity avoidance and use of assistive device. CONCLUSION: The increased risk of falls in patients with chronic obstructive pulmonary disease warrants attention in order to reduce serious and adverse health consequences of falls.
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| 24. |
- Hellström, Margareta, et al.
(author)
-
ENVRI-FAIR D6.3: Training for FAIR services and data – outcomes and experiences
- 2023
-
Reports (other academic/artistic)abstract
- This is the final deliverable of WP6, the training and capacity building work package of ENVRI-FAIR. The objectives of WP6 were to provide training to ENVRIs and key ENVRI stakeholder groups about the FAIR principles, how to implement these in practice in RI services and data management activities at data centre level, how to evaluate the degree of implementation using FAIR metrics, as well as relevant legal and policy requirements. This deliverable report summarises the activities we have undertaken, with special focus on the preparation and running of training events aimed at the ENVRIs’ data centre staff. We also describe the infrastructure that was developed to provide a comprehensive Learning Environment for the ENVRI Community, including a catalogue, learning platform and repository and the Training Gateway component of the ENVRI-Hub. Finally, the report also contains an extensive discussion of “lessons learned” that we hope will be of use for future ENVRI Community training activities.
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| 25. |
- Hellström, Margareta, et al.
(author)
-
Identification and citation of digital research resources
- 2020
-
In: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). - Cham : Springer International Publishing. - 1611-3349 .- 0302-9743. - 9783030528294 - 9783030528287 ; 12003, s. 162-175
-
Book chapter (peer-reviewed)abstract
- Environmental research infrastructures are often built on a large number of distributed observational or experimental sites, run by hundreds of scientists and technicians, financially supported and administrated by a large number of institutions. It becomes very important to acknowledge the data sources and their providers. There is also a strong need for common data citation tracking systems that allow data providers to identify downstream usage of their data so as to demonstrate their importance and show the impact to stakeholders and the public. This chapter highlights identification and citation in environmental RIs, reviews available technologies and develops common services for these operations. This chapter presents a suggested common system design for Identification and Citation, as well as an outline for negotiations and discussions with publishers and other actors in the scholarly data management and curation world.
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| 26. |
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| 27. |
- Hellström, Per M., et al.
(author)
-
Normal gastric emptying time of a carbohydrate-rich drink in elderly patients with acute hip fracture : a pilot study
- 2017
-
In: BMC Anesthesiology. - : Springer Science and Business Media LLC. - 1471-2253 .- 1471-2253. ; 17
-
Journal article (peer-reviewed)abstract
- Background: Guidelines for fasting in elderly patients with acute hip fracture are the same as for other trauma patients, and longer than for elective patients. The reason is assumed stress-induced delayed gastric emptying with possible risk of pulmonary aspiration. Prolonged fasting in elderly patients may have serious negative metabolic consequences. The aim of our study was to investigate whether the preoperative gastric emptying was delayed in elderly women scheduled for surgery due to acute hip fracture. Methods: In a prospective study gastric emptying of 400 ml 12.6% carbohydrate rich drink was investigated in nine elderly women, age 77-97, with acute hip fracture. The emptying time was assessed by the paracetamol absorption technique, and lag phase and gastric half-emptying time was compared with two gender-matched reference groups: ten elective hip replacement patients, age 45-71 and ten healthy volunteers, age 28-55. Results: The mean gastric half-emptying time in the elderly study group was 53 +/- 5 (39-82) minutes with an expected gastric emptying profile. The reference groups had a mean half-emptying time of 58 +/- 4 (41-106) and 59 +/- 5 (33-72) minutes, indicating normal gastric emptying time in elderly with hip fracture. Conclusion: This pilot study in women with an acute hip fracture shows no evidence of delayed gastric emptying after an orally taken carbohydrate-rich beverage during the pre-operative fasting period. This implies no increased risk of pulmonary aspiration in these patients. Therefore, we advocate oral pre-operative management with carbohydrate-rich beverage in order to mitigate fasting-induced additive stress in the elderly with hip fracture.
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| 28. |
- Hellström Ängerud, Karin, et al.
(author)
-
Areas for quality improvements in heart failure care : quality of care from the patient's perspective
- 2017
-
In: Scandinavian Journal of Caring Sciences. - Hoboken : John Wiley & Sons. - 0283-9318 .- 1471-6712. ; 31:4, s. 830-838
-
Journal article (peer-reviewed)abstract
- BACKGROUND: Heart failure is a serious condition with high mortality and a high symptom burden. Most patients with heart failure will be taken care of in primary care but the knowledge of how the quality of care is perceived by patients with heart failure is limited.OBJECTIVE: The aim was to explore how patients with heart failure report quality of care, in an outpatient setting.METHODS: Seventy-one patients with a confirmed diagnosis of heart failure and who were cared for in an outpatient setting were included in this cross-sectional study. Quality of care was assessed with a short form of the Quality from the Patient's Perspective questionnaire. The items measured four dimensions, and each item consists of both perceived reality of the received care and its subjective importance.RESULTS: Inadequate quality was identified in three out of four dimensions and in items without dimension affiliation. In total, inadequate quality was identified in 19 out of 25 items. Patients reported the highest level of perceived reality in 'my family member was treated well' and the lowest perceived reality in 'effective treatment for loss of appetite'. Effective treatment for shortness of breath was of the highest subjective importance for the patients.CONCLUSION: Important areas for improvement in the quality of care for patients with heart failure in an outpatient setting were identified, such as symptom alleviation, information, participation and access to care.
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| 29. |
- Hellström Ängerud, Karin, et al.
(author)
-
Areas for quality improvements in heart failure care: quality of care from the family members' perspective
- 2018
-
In: Scandinavian Journal of Caring Sciences. - Hoboken : Wiley. - 0283-9318 .- 1471-6712. ; 32:1, s. 346-353
-
Journal article (peer-reviewed)abstract
- BackgroundThe complex needs of people with chronic heart failure (HF) place great demands on their family members, and it is important to ask family members about their perspectives on the quality of HF care. ObjectiveTo describe family members' perceptions of quality of HF care in an outpatient setting. MethodsA cross-sectional study using a short form of the Quality from Patients' Perspective (QPP) questionnaire for data collection. The items in the questionnaire measure four dimensions of quality, and each item consists of both the perceived reality of the care and its subjective importance. The study included 57 family members of patients with severe HF in NYHA class III-IV. ResultsFamily members reported areas for quality improvements in three out of four dimensions and in dimensionless items. The lowest level of perceived reality was reported for treatment for confusion and loss of appetite. Treatment for shortness of breath, access to the apparatus and access to equipment necessary for medical care were the items with the highest subjective importance for the family members. ConclusionFamily members identified important areas for quality improvement in the care for patients with HF in an outpatient setting. In particular, symptom alleviation, information to patients, patient participation and access to care were identified as areas for improvements. Thus, measuring quality from the family members' perspective with the QPP might be a useful additional perspective when it comes to the planning and implementation of changes in the organisation of HF care.
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| 30. |
- Hellström Ängerud, Karin, et al.
(author)
-
Symptoms of Acute Myocardial Infarction as Described in Calls to Tele-Nurses and in Questionnaires
- 2023
-
In: Journal of Cardiovascular Nursing. - : Wolters Kluwer. - 0889-4655 .- 1550-5049. ; 38:2, s. 150-157
-
Journal article (peer-reviewed)abstract
- Background: Patient-reported symptoms of acute myocardial infarction (MI) may be affected by recall bias depending on when and where symptoms are assessed.Aim: The aim of this study was to gain an understanding of patients' symptom description in more detail before and within 24 hours after a confirmed MI diagnosis.Methods: A convergent parallel mixed-methods design was used to examine symptoms described in calls between the tele-nurse and the patient compared with symptoms selected by the patient from a questionnaire less than 24 hours after hospital admission. Quantitative and qualitative data were analyzed separately and then merged into a final interpretation.Results: Thirty patients (median age, 67.5 years; 20 men) were included. Chest pain was the most commonly reported symptom in questionnaires (24/30). Likewise, in 19 of 30 calls, chest pain was the first complaint mentioned, usually described together with the symptom onset. Expressions used to describe symptom quality were pain, pressure, discomfort, ache, cramp, tension, and soreness. Associated symptoms commonly described were pain or numbness in the arms, cold sweat, dyspnea, weakness, and nausea. Bodily sensations, such as feeling unwell or weak, were also described. Fear and tiredness were described in calls significantly less often than reported in questionnaires (P = .01 and P = .02), whereas “other” symptoms were more often mentioned in calls compared with answers given in the questionnaire (P = .02). Some symptoms expressed in the calls were not listed in the questionnaire, which expands the understanding of acute MI symptoms. The results showed no major inconsistencies between datasets.Conclusion: Patients' MI symptom descriptions in tele-calls and those reported in questionnaires after diagnosis are comparable and convergent.
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| 31. |
- Hoischen, Robert, et al.
(author)
-
Isomeric Mirror States as Probes for Effective Charges in the Lower pf Shell
- 2011
-
In: Journal of Physics G: Nuclear and Particle Physics. - : IOP Publishing. - 0954-3899 .- 1361-6471. ; 38:3
-
Journal article (peer-reviewed)abstract
- Following the fragmentation of a 550 MeV u(-1)primary beam of Ni-58, time-and energy-correlated gamma decays from isomeric states in neutron-deficient nuclei in the 1f(7/2) shell have been identified using the GSI fragment separator in combination with the RISING Ge-detector array. The results on isomers in the mirror pairs Ti-43(22)21-Sc-43(21)22 (I-pi = 3/2(+) and 19/2(-)), Cr-45(24)21-Sc-45(21)24 (I-pi = 3/2(+)) and V-45(23)22-Ti-45(22)23 (I-pi = 3/2(-)) are discussed in the framework of large scale pf and sdpf shell-model calculations, the former in conjunction with isospin symmetry breaking effects with emphasis on effective charges.
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| 32. |
- Holmlund, Lena, et al.
(author)
-
Health‐related quality of life in patients with heart failure eligible for treatment with sacubitril–valsartan
- 2020
-
In: Nursing Open. - : John Wiley & Sons. - 2054-1058. ; 7:2, s. 556-562
-
Journal article (peer-reviewed)abstract
- Aim: To describe and compare self‐reported health‐related quality of life between younger and older patients with severe heart failure eligible for treatment with sacubitril–valsartan and to explore the association between health‐related quality of life and age, NYHA classification, systolic blood pressure and NT‐proBNP level.Design: Cross‐sectional study.Methods: A total of 59 patients, eligible for treatment with sacubitril–valsartan were consecutively included and divided into a younger (≤75 years) and older group (>75 years). Health‐related quality of life was assessed using the Kansas City Cardiomyopathy Questionnaire and the EuroQol 5‐dimensions. Data were collected between June 2016 and January 2018. The STROBE checklist was used.Results: There were no differences in overall health‐related quality of life between the age groups. The older patients reported lower scores in two domains measured with the Kansas City Cardiomyopathy Questionnaire, namely self‐efficacy (67.0 SD 22.1 vs. 78.8 SD 19.7) and physical limitation (75.6 SD 19.0 vs. 86.3 SD 14.4). Higher NYHA class was independently associated with lower Kansas City Cardiomyopathy Questionnaire Overall Summary Score.
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| 33. |
- Hök Wikstrand, Margareta, 1946, et al.
(author)
-
Abnormal vessel morphology in boys born after intracytoplasmic sperm injection.
- 2008
-
In: Acta paediatrica (Oslo, Norway : 1992). - : Wiley. - 1651-2227 .- 0803-5253. ; 97:11, s. 1512-7
-
Journal article (peer-reviewed)abstract
- AIM: Children born after intracytoplasmic sperm injection (ICSI) are at risk of preterm birth, low birth weight and perinatal morbidity which may predispose for diseases of the central nervous and vascular systems. Our aim was to investigate the ocular fundus morphology in children born after ICSI. METHOD: Children born after ICSI (n = 82) had ocular fundus photographs taken at the age of 5 years and results were compared with those of a control group (n = 203). The ocular fundus morphology with the central retinal vessels was evaluated by digital image analysis. RESULTS: Children born after ICSI (n = 57) had abnormal retinal vascularization as evidenced by a lower number of vascular branching points compared with the control group (n = 181) (p = 0.0002). A gender difference was found whereby the ICSI boys (n = 35) had significantly fewer retinal branching points (median 24, range 19-29.5) compared with the control boys (median 27.5, range 20-37) (p < 0.0001). CONCLUSION: Our findings showed that ICSI boys have abnormal vessel morphology as demonstrated by a reduced number of central retinal branching points. The difference still remained after elimination of factors earlier shown to be associated with a low number of vascular branching points, i.e. low birth weight and preterm, suggesting other mechanisms responsible for the low number of vascular branching points.
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| 34. |
- Hök Wikstrand, Margareta, 1946, et al.
(author)
-
Birth weight deviation and early postnatal growth are related to optic nerve morphology at school age in children born preterm.
- 2010
-
In: Pediatric research. - 1530-0447. ; 67:3, s. 325-9
-
Journal article (peer-reviewed)abstract
- The aim of this study was to evaluate the influence of early and later postnatal growth variables on optic disc morphology in children (n = 53) born at gestational age <32 wk. On fundus photographs taken at a median age of 5.4 y, the optic discs were evaluated using digital image analysis and compared with those of a control group (n = 203). The results were analyzed in relation to gestational age, birth weight (BW) SD score (SDS), IGF-1 weight at postmenstrual age 32 wk (SDS), and weight, length, and head circumference (SDS) at follow-up. The preterm children's optic disc and neuronal rim areas were smaller than in the control group. Low BW (SDS) and weight at wk 32 (SDS) were associated with larger area of the optic cup and reduced neuronal rim area. Preterm children with known brain lesions (n = 6) had significantly larger cups than preterm children without known brain lesions. The association found between both low BW and poor early growth and later reduced neuronal tissue of the optic nerve indicate that early weight gain is important for neural development in preterm children.
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| 35. |
- Hök Wikstrand, Margareta, 1946, et al.
(author)
-
Early postnatal growth variables are related to morphologic and functional ophthalmologic outcome in children born preterm.
- 2010
-
In: Acta paediatrica. - : Wiley. - 1651-2227 .- 0803-5253. ; 99:5, s. 658-664
-
Journal article (peer-reviewed)abstract
- Aim: To evaluate the association between gestational age (GA), early and late postnatal growth variables and ophthalmologic outcome in ex-preterm children. Methods: Children (GA < 32 weeks, n = 66), previously examined regarding insulin-like growth factor 1 (IGF-1) serum concentrations in relation to ROP, underwent ophthalmologic examination at median 5.6 years. Weight, height, and head circumference (HC) were measured and expressed as SDS. Growth variables were analysed in relation to ophthalmologic outcome. Results: At follow-up 74% had some ophthalmologic abnormality and 17% had visual impairment. Poor visual acuity was correlated with low GA (r(s) = 0.29, p = 0.019), low weight at 32 weeks (r(s) = 0.30, p = 0.013), and low weight (r(s) = 0.37, p = 0.0025), height (r(s) = 0.41, p = 0.0007) and HC (r(s) = 0.55, p < 0.0001) at follow-up. Hyperopic children (25%) had low neonatal IGF-1 (p = 0.0096) and HC at follow-up (p = 0.022). Poor visual perception was correlated with low early weight (r(s) = 0.38, p = 0.0036) and HC at follow-up (r(s) = 0.39, p = 0.0024). Head circumference at follow-up was correlated with GA (r(s) = 0.40, p = 0.0012), neonatal IGF-1 (r(s) = 0.37, p = 0.0031), and early weight (r(s) = 0.27, p = 0.035). Conclusions: In very preterm children, early and later postnatal growth is closely related to visual acuity and perception at follow-up. In addition, IGF-1 concentrations and early growth are correlated with head circumference and refraction at follow-up.
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| 36. |
- Hök Wikstrand, Margareta, 1946, et al.
(author)
-
Maternal and neonatal factors associated with poor early weight gain and later retinopathy of prematurity.
- 2011
-
In: Acta paediatrica (Oslo, Norway : 1992). - : Wiley. - 1651-2227 .- 0803-5253.
-
Journal article (peer-reviewed)abstract
- Aim: To identify factors associated with poor early weight gain as reflected in an alarm system, WINROP and risk of later proliferative ROP in infants with gestational age <28 weeks. Methods: Infants with a WINROP alarm and proliferative ROP, the "alarm group" (n=23) were matched to gestational age and gender to a "no alarm group" (n=23) with no WINROP alarm and no or mild ROP. Retrospectively maternal variables, birth characteristics and neonatal factors, during the first three postnatal weeks, were compared. Results: The "alarm group" had lower birth weight and birth weight standard deviation score, longer stay in ventilator, more insulin and corticosteroid treatments, and lower white blood cell count. In a logistic regression model birth weight standard deviation score, insulin, low white blood cell count, absence of both elevated C- reactive protein and premature rupture of membranes were associated with proliferative ROP and WINROP alarm (p=0.000, r(2) = 0.704). Conclusions: This study shows that prenatal factors resulting in low birth weight have persisting effects on early postnatal growth, metabolism and inflammatory response. Future prospective studies will focus on the link between these factors and pathological retinal vessel development in the early postnatal period to find possible preventive strategies.
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| 37. |
- Hök Wikstrand, Margareta, 1946, et al.
(author)
-
Ophthalmological findings in children born after intracytoplasmic sperm injection
- 2006
-
In: Acta Ophthalmol Scand. ; 84:2, s. 177-81
-
Journal article (peer-reviewed)abstract
- PURPOSE: To investigate visual function and ocular morphology in children born after intracytoplasmic sperm injection (ICSI) and compare them with visual function and ocular morphology in matched children born after spontaneous conception. METHODS: A total of 137 children born after ICSI and 159 control children were examined at the age of 5 years in a blinded study. The two groups were matched for age, gender and maternal age. The children underwent a detailed ophthalmological investigation by an ophthalmologist and an orthoptist. RESULTS: A total of 90.4% of the ICSI children had a visual acuity (VA) in the better eye of >or= 0.8, compared with 93.7% of the controls (NS). No significant differences were found between ICSI children and controls with regard to hyperopia, myopia, astigmatism, heterotropia, stereoscopic vision and convergence. One child with Goldenhar syndrome and one with Marcus Gunn syndrome were observed in the ICSI group. One child in the ICSI group was treated for retinopathy of prematurity. CONCLUSION: In this limited study group, no significant differences in visual function and/or ocular morphology were found between children born after ICSI and matched control children at the age of 5 years.
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| 38. |
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| 39. |
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| 40. |
- Jungclaus, A., et al.
(author)
-
Observation of isomeric decays in the r-process waiting-point nucleus Cd-130(82)
- 2007
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 99:13
-
Journal article (peer-reviewed)abstract
- The gamma decay of excited states in the waiting-point nucleus Cd-130(82) has been observed for the first time. An 8(+) two-quasiparticle isomer has been populated both in the fragmentation of a Xe-136 beam as well as in projectile fission of U-238, making Cd-130 the most neutron-rich N=82 isotone for which information about excited states is available. The results, interpreted using state-of-the-art nuclear shell-model calculations, show no evidence of an N=82 shell quenching at Z=48. They allow us to follow nuclear isomerism throughout a full major neutron shell from Cd-98(50) to Cd-130(82) and reveal, in comparison with Ni-76(48) one major proton shell below, an apparently abnormal scaling of nuclear two-body interactions.
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| 41. |
- Järup, Lars, et al.
(author)
-
Low level exposure to cadmium and early kidney damage : The OSCAR study
- 2000
-
In: Occupational and Environmental Medicine. - : BMJ. - 1351-0711 .- 1470-7926. ; 57:10, s. 668-672
-
Journal article (peer-reviewed)abstract
- Objectives - To study the dose-response relation between cadmium dose and renal tubular damage in a population of workers and people environmentally or occupationally exposed to low concentrations of cadmium. Methods - Early kidney damage in 1021 people, occuptionally or environmentally exposed to cadmium, was assessed from cadmium in urine to estimate dose, and protein HC (a1-microglobulin) in urine to assess tubular pvoteinuria. Results - There was an age and sex adjusted correlation between cadmium in urine and urinary protein HC. The prevalence of tubular proteinuria ranged from 5% among unexposed people to 50% in the most exposed group. The corresponding prevalence odds ratio was 6.0 (95% confidence interval (95% CI) 1.6 to 22) for the highest exposure group, adjusted for age and sex. Multiple logistic regression analysis showed an increasing prevalence of tubular proteinuria with urinary cadmium as well as with age. After adjusment to the mean age of the study population (53 years), the results show an increased prevalence of 10% tubular proteinuria (taking into account a background prevalence of 5%) at a urinary cadmium concentration of 1.0 nmol/mmol creatinine. Conclusion - Renal tubular damage due to exposure to cadmium develops at lower levels of cadmium body burden than previously anticipated.
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| 42. |
- Jönsson, Anna Maria, et al.
(author)
-
Annual changes in MODIS vegetation indices of Swedish coniferous forests in relation to snow dynamics and tree phenology
- 2010
-
In: Remote Sensing of Environment. - : Elsevier BV. - 0034-4257 .- 1879-0704. ; 114:11, s. 2719-2730
-
Journal article (peer-reviewed)abstract
- Remote sensing provides spatially and temporally continuous measures of forest reflectance, and vegetation indices calculated from satellite data can be useful for monitoring climate change impacts on forest tree phenology. Monitoring of evergreen coniferous forest is more difficult than monitoring of deciduous forest, as the new buds only account for a small proportion of the green biomass, and the shoot elongation process is relatively slow. In this study, we have analyzed data from 186 coniferous monitoring sites in Sweden covering boreal, southern-boreal, and boreo-nemoral conditions. Our objective was to examine the possibility to track seasonal changes in coniferous forests by time-series of MODIS eight-day vegetation indices, testing the coherence between satellite monitored vegetation indices (VI) and temperature dependent phenology. The relationships between two vegetation indices (NDVI and WDRVI) and four phenological indicators (length of snow season, modeled onset of vegetation period, tree cold hardiness level and timing of budburst) were analyzed. The annual curves produced by two curve fitting methods for smoothening of seasonal changes in NDVI and WDRVI were to a large extent characterized by the occurrence of snow, producing stable seasonal oscillations in the northern part and irregular curves with less pronounced annual amplitude in the southern part of the country. Measures based on threshold values of the VI-curves, commonly used for determining the timing of different phenological phases, were not applicable for Swedish coniferous forests. Evergreen vegetation does not have a sharp increase in greenness during spring, and the melting of snow can influence the vegetation indices at the timing of bud burst in boreal forests. However, the interannual variation in VI-values for specific eight-day periods was correlated with the phenological indicators. This relation can be used for satellite monitoring of potential climate change impacts on northern coniferous spring phenology. (C) 2010 Elsevier Inc. All rights reserved.
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| 43. |
- Karlsson, Göran, et al.
(author)
-
Are we ready to move towards a new type of teacher training? : Case study: The WETEN project
- 2011
-
In: eLmL - International Conference on Mobile, Hybrid, and On-line Learning. - 9781612081205 ; , s. 36-39
-
Conference paper (peer-reviewed)abstract
- To assure a quality learning process in Higher Education, continuous training of teachers is a priority. This paper is a case study about the training of trainers organized in the WETEN project, presenting how the topics were chosen, how the educational technologies and facilitation contributed to the building of learning community.
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| 44. |
- Lalkovski, S., et al.
(author)
-
Core-coupled states and split proton-neutron quasiparticle multiplets in Ag122-126
- 2013
-
In: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 87:3, s. 034308-
-
Journal article (peer-reviewed)abstract
- Neutron-rich silver isotopes were populated in the fragmentation of a Xe-136 beam and the relativistic fission of U-238. The fragments were mass analyzed with the GSI Fragment Separator and subsequently implanted into a passive stopper. Isomeric transitions were detected by 105 high-purity germanium detectors. Eight isomeric states were observed in Ag122-126 nuclei. The level schemes of Ag-122,Ag-123,Ag-125 were revised and extended with isomeric transitions being observed for the first time. The excited states in the odd-mass silver isotopes are interpreted as core-coupled states. The isomeric states in the even-mass silver isotopes are discussed in the framework of the proton-neutron split multiplets. The results of shell-model calculations, performed for the most neutron-rich silver nuclei are compared to the experimental data.
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| 45. |
- Mineva, Milena, et al.
(author)
-
A New us Isomer in 136Sb Produced in the Projectile Fission of 238U
- 2001
-
In: European Physical Journal A. Hadrons and Nuclei. - 1434-6001. ; 11, s. 9-13
-
Journal article (peer-reviewed)abstract
- The neutron-rich isotope Sb-136 has been produced following the relativistic projectile fission of U-238 in an experiment performed at the Fragment Separator at GSI, Darmstadt. Delayed gamma -ray spectroscopy of the fission products has been performed after isotope separation. A new isomeric state in Sb-136 has been populated, and its lifetime measured as T-1/2 = 565(50) ns. Realistic and empirical shell-model calculations have been performed and are compared to the experimental observables.
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| 46. |
- Männikkö Barbutiu, Sirkku, et al.
(author)
-
Kompetensutveckling
- 2012
-
In: Digital kompetens i lärarutbildningen. - Lund : Studentlitteratur AB. - 9789144082196 ; , s. 65-79
-
Book chapter (other academic/artistic)
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| 47. |
- Naqvi, F., et al.
(author)
-
Isomer spectroscopy of (127)Cd
- 2010
-
In: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 82:3, s. 034323-
-
Journal article (peer-reviewed)abstract
- The spin and configurational structure of excited states of (127)Cd, the two-proton and three-neutron hole neighbor of (132)Sn, has been studied. An isomeric state with a half-life of 17.5(3) mu s was populated in the fragmentation of a (136)Xe beam on a (9)Be target at a beam energy of 750 MeV/u. Time distributions of the delayed gamma transitions and gamma gamma coincidence relations were exploited to construct a decay scheme. The observed yrast (19/2)(+) isomer is proposed to have dominant configurations of nu(h(11/2)(-3))pi(g(9/2)(-1), p(1/2)(-1)), nu(h(11/2)(-2)d(3/2)(-1))pi(g(9/2)(-2)), and nu(h(11/2)(-2), s(1/2)(-1))pi(g(9/2)(-2)) and to decay by two competing stretched M2 and E3 transitions. Experimental results are compared with the isotone (129)Sn. The new information provides input for the proton-neutron interaction and the evolution of neutron hole energies in nuclei around the doubly magic (132)Sn core.
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| 48. |
- Ossiannilsson, Ebba, et al.
(author)
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International Benchmarking : The first dual mode distance distance learning benchmarking club
- 2012
-
In: 1st conference, Next Generation Learning, Falun, Sweden, februrary 21-23 2012. - 9789185941476 ; , s. 91-103
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Conference paper (peer-reviewed)abstract
- Benchmarking is a self-improvement tool allowing organisations to compare themselves with others regarding some aspects of performance, with a view to finding ways to improve current performance. Benchmarking deals with change for quality enhancement but also with identification and implementation of areas of development. Benchmarking is a process that enables comparison of inputs, processes or outputs between institutions or within a single institution over time A Dual Modes Distance Learning Benchmarking Club was set up across the world, aimed at disseminating and implementing the Pick&Mix model. Four institutions in the Club were successfully benchmarked using a slightly modified version of Pick&Mix during 2009-2010. Besides the benchmarking, concordance works with other benchmarking methods were conducted. The Pick&Mix benchmarking system contains 18 criteria which are critical success factors (of special importance for success in e-learning).1 These are: Usability, e-Learning Strategy, Decisions on Projects, Training, Costs, Planning Annually, Technical Support to Staff, Decisions on Programmes, Leadership in e-Learning, Management Style, Relationship, Management Upwards, Reliability, Market Research, Security, Student Understanding of System, Student Help Desk, Distance Learning Strategy (doppelganger criterion with e-learning strategy). All of the benchmarks were scored at six levels (a scale of 1 to 6) and a coloured matrix was produced where the state of an institution/department becomes explicit. Among four institutions in the Club that went through to scoring, one was in UK (University of Leicester), two in Sweden (Lund University and the Royal Institute of Technology), and one in Canada (Thompson Rivers University). Later, the University of Leicester decided not to continue in the Club, due to changes in staff and policies. Fortunately Gotland University, Sweden had also done benchmarking using the Pick&Mix methodology. A final meeting of the Club was hosted by KTH in September 2011 with Thompson Rivers University and Lund University with Gotland University as a guest. The four universities present agreed to share their results and to continue their benchmarking collaboration in Sweden and beyond, including producing a public report of their conclusions. This paper is the first airing of these. Headline conclusions are: 1. Over the five years since Pick&Mix was first used, institutions are gradually developing stronger competence in e-learning – but progress is slow 2. Only a very few universities have strong expertise in market research for e-learning 3. No institution has a good understanding of the cost issues to do with e-learning Staff generally feel that the management do not given them adequate reward and recognition for their e-learning competence. 1 Re.ViCa http://revica.europace.org
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- Ossiannilsson, Ebba, et al.
(author)
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Internationell benchmarking av e-lärande
- 2012
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In: SVERDnytt. - 2001-5429. ; :1, s. 6-7
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Journal article (other academic/artistic)abstract
- Benchmarking är en själv-värderingsmetod som gör det möjligt för organisationer att jämföra sig med andra gällande vissa prestanda- och utförandeaspekter. Syftet är att finna goda exempel, sätt att förbättra nuvarande situation samt förstå i vilket tillstånd den egna organisationen befinner sig i vad gäller dessa aspekter. Benchmarking handlar om förändring för kvalitetsutveckling men också om identifiering och genomförande av utvecklingsområden
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