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1.	Astrom, M, et al. (author) Evidence for a bimodal relation between serum lysozyme and prognosis in 232 patients with acute myeloid leukaemia 2003 In: European journal of haematology. - : Wiley. - 0902-4441. ; 70:1, s. 26-33 Journal article (peer-reviewed)
2.	E Johnsen, H, et al. (author) Priming with r-metHuSCF and filgrastim or chemotherapy and filgrastim in patients with malignant lymphomas: a randomized phase II pilot study of mobilization and engraftment 2011 In: BONE MARROW TRANSPLANTATION. - : Nature Publishing Group. - 0268-3369 .- 1476-5365. ; 46:1, s. 44-51 Journal article (peer-reviewed)abstract SCF has been shown to synergize with G-CSF to mobilize CD34(+) PBPCs. In this study we report results from this combination after a phase II trial of 32 patients with malignant lymphoma randomized to receive recombinant methionyl human SCF (ancestim, r-metHuSCF) in combination with recombinant methionyl human G-CSF (filgrastim, r-metHuG-CSF) (experimental arm A) or routine chemotherapy plus filgrastim (conventional arm B). The primary objective was to evaluate the side effects and toxicity during priming and mobilization. The secondary objectives were efficacy by the level of blood-circulating PBPCs, the number of harvest days and the time to three-lineage engraftment after autografting. First, during priming 5 patients had 8 serious events, 4 in each arm. A summary of all adverse events revealed 30 (94%) patients suffering from 132 events of all grading. Second, neutropenia and thrombocytopenia was documented in arm B. Third, 9/14 (64%) patients in arm A reached the target of 5 million CD34(+) cells/kg body weight (bw) compared with 13/15 (87%) in arm B. The results represent the first randomized trial of growth factor plus chemotherapy priming and indicate that a formal phase III trial very unlikely may challenge chemotherapy plus r-metHuG-CSF priming in candidates for high-dose therapy.
3.	Hornsten, L, et al. (author) Bisallylic hydroxylation of linoleic and arachidonic acids by adult and fetal human liver microsomes and a comparison with human recombinant cytochromes P450 1997 In: Advances in experimental medicine and biology. - Boston, MA : Springer US. - 0065-2598. ; 433, s. 123- Journal article (peer-reviewed)
4.	Hornsten, L, et al. (author) Cloning of linoleate diol synthase reveals homology with prostaglandin Hsynthases. 1999 In: J Biol Chem. ; 274, s. 28219- Journal article (peer-reviewed)
5.	Johnsen, H E, et al. (author) Outcome for patients with leukemia, multiple myeloma and lymphoma who relapse after high dose therapy and autologous stem cell support 1996 In: Leukemia and Lymphoma. ; 24, s. 81- Journal article (peer-reviewed)
6.	Wahlin, A, et al. (author) Outcome of a multicenter treatment program including autologous or allogeneic bone marrow transplantation for de novo acute myeloid leukemia 1997 In: European Journal of Haematology. ; 58, s. 233- Journal article (peer-reviewed)

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Result 1-6 of 6

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Type of publication: journal article (6)

Type of content: peer-reviewed (6)

Author/Editor: Hornsten, P (4); Brinch, L (2); Remes, K (2); Tidefelt, U (2); Wahlin, A (2); Geisler, C. (2); show more...; Oliw, EH (2); Hornsten, L (2); Lehtinen, M (1); Garosi, P. (1); Paoletti, R. (1); Juliusson, Gunnar (1); Schroder, H (1); Bjorkstrand, B (1); Bjorkholm, M (1); HELLMAN, U (1); Bodin, L. (1); Astrom, M. (1); Samuelsson, B (1); GRUBER, A (1); Sinzinger, H (1); Vane, JR (1); Ramwell, P (1); Wong, PYK (1); Sallerfors, B (1); Carlson, K (1); Simonsson, B. (1); Wernstedt, C (1); Bergmann, O. J. (1); Daugaard, G (1); Ruutu, T (1); Hedenus, M (1); OBERG, G (1); Kvaloy, S (1); Kvalheim, G (1); Schmitz, A. (1); Juvonen, E (1); Pedersen, L M (1); Bylund, J (1); Fast, A (1); Evensen, SA (1); Su, C. (1); E Johnsen, H (1); Jurgensen, G W (1); Boegsted, M (1); Malm, A (1); Carneskog, J (1); Osbourn, AE (1); Johnsen, H.E. (1); Blystad, A (1); show less...

University: Uppsala University (4); Karolinska Institutet (2); Linköping University (1)

Language: English (6)

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