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- El-Sayed, Najib M., et al.
(author)
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The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease.
- 2005
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In: Science. - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 309:5733, s. 409-15
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Journal article (peer-reviewed)abstract
- Whole-genome sequencing of the protozoan pathogen Trypanosoma cruzi revealed that the diploid genome contains a predicted 22,570 proteins encoded by genes, of which 12,570 represent allelic pairs. Over 50% of the genome consists of repeated sequences, such as retrotransposons and genes for large families of surface molecules, which include trans-sialidases, mucins, gp63s, and a large novel family (>1300 copies) of mucin-associated surface protein (MASP) genes. Analyses of the T. cruzi, T. brucei, and Leishmania major (Tritryp) genomes imply differences from other eukaryotes in DNA repair and initiation of replication and reflect their unusual mitochondrial DNA. Although the Tritryp lack several classes of signaling molecules, their kinomes contain a large and diverse set of protein kinases and phosphatases; their size and diversity imply previously unknown interactions and regulatory processes, which may be targets for intervention.
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2. |
- Huang, Dan, et al.
(author)
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Infrared Drying Characteristics and Quality Variations of Lily Bulbs Under Blanching Pretreatment
- 2022
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In: Journal of Thermal Science and Engineering Applications. - : ASME International. - 1948-5085 .- 1948-5093. ; 14:9
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Journal article (peer-reviewed)abstract
- Infrared drying characteristics and quality variations (color change, hardness, contents of polyphenol and flavonoid) of lily bulbs under blanching pretreatment are investigated. Influences of parameters such as pretreatment temperature and time and infrared drying temperature are discussed. Effective moisture diffusivity coefficient, activation energy, and energy consumption were calculated. Results showed that drying time was reduced by 62.5%, 56.3%, and 61.5% at 90 °C compared to 60 °C when blanching time was 4, 5, and 6 min, respectively. A blanching time of 5 min and drying temperature of 70 °C were ideal for pretreatment and drying to maintain good color quality. Hardness value of lily bulb decreased as drying temperature and blanching time increased. Seventy to eighty degree celcius was ideal drying condition to maintain good hardness quality. Blanching time and drying temperature differently affected contents of flavonoids and polyphenols of lily bulbs. Basically, when blanching time was relatively long and drying temperature was relatively high, the content of polyphenols was high.
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