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| 5. |
- Ellegård, Kajsa, 1951, et al.
(author)
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Reflective Production in the Final Assembly of Motor Vehicles - An Emerging Swedish Challenge
- 1992
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In: International Journal of Operations and Production Management. - 1758-6593 .- 0144-3577. ; 12:7/8, s. 117-133
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Journal article (peer-reviewed)abstract
- Presents some theoretical principles and empirical evidence relating to the new Swedish production systems for final assembly of motor vehicles. Contends that in these production systems it is possible simultaneously to enhance efficiency and quality of working life. Briefly sketches three production forms as they apply to the final assembly of automobiles and discusses the societal environments in which these different forms of production have evolved. It focuses on Volvo Uddevalla plant as one of the main examples so far of a reflective production system for final assembly of automobiles. Amplifies the analysis of different production flow patterns for final assembly and in particular addresses the issue of semi‐parallel mechanistic production flow and parallel organic production flow as alternatives to serial flow on a conventional line assembly. A comment: This publication is authored together with e.g. senior research competencies (1) within vocational learning and training as well as (2) within time-geography with whom Engström have had long time cooperation procedures. But also personal at our department/research group (Mats Johansson) well as our knowledgeable contact person (Bertil Johansson) within Volvo contributed (he has really helped us out for decades and was responsible for the continuous contacts with Volvo in most any matter).
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| 6. |
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| 7. |
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| 8. |
- Hauber, Ernst, et al.
(author)
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MORPHOMETRY OF ALLUVIAL FANS IN A POLAR DESERT (SVALBARD, NORWAY): IMPLICATIONS FOR INTERPRETING MARTIAN FANS.
- 2009
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In: 40th Lunar and Planetary Science Conference. ; :1648
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Conference paper (peer-reviewed)abstract
- Alluvial fan-like landforms have been identified on Mars. Since alluvial fans are recorders of processes that are sensitive to climatic conditions, the investigation of possible Martian fans can reveal information about the planet`s climate. In lieu of direct observations of active depositional processes on Martian fans, comparisons with terrestrial analogues can constrain models of Martian fan formation derived from remote sensing data. Since present-day Mars is cold and dry, alluvial fans formed in cold deserts should be considered as useful analogues. The probably closest climatic analogue to Mars on Earth are the Antarctic Dry Valleys , but polar deserts can also be found in the Arctic. We report on our field work in summer 2008 and a simultaneous flight campaign with an airborne version (HRSC-AX) of the High Resolution Stereo Camera (HRSC) onboard Mars Express. The results are compared with measurements of Martian fans, based on HRSC DEM.
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| 9. |
- Hauber, Ernst, et al.
(author)
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Periglacial landscapes on Svalbard: Terrestrial analogs for cold-climate landforms on Mars
- 2011
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In: The Geological Society of America, Special Paper. - : Geological Society of America. ; 483
-
Journal article (peer-reviewed)abstract
- We present landforms on Svalbard (Norway) as terrestrial analogs for possible Martian periglacial surface features. While there are closer climatic analogs for Mars, e.g., the Antarctic Dry Valleys, Svalbard has unique advantages that make it a very useful study area. Svalbard is easily accessible and offers a periglacial landscape where many different landforms can be encountered in close spatial proximity. These landforms include thermal contraction cracks, slope stripes, rock glaciers, protalus ramparts, and pingos, all of which have close morphological analogs on Mars. The combination of remotesensing data, in particular images and digital elevation models, with field work is a promising approach in analog studies and facilitates acquisition of fi rst-hand experience with permafrost environments. Based on the morphological ambiguity of certain landforms such as pingos, we recommend that Martian cold-climate landforms should not be investigated in isolation, but as part of a landscape system in a geological context.
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| 10. |
- Hauber, Ernst, et al.
(author)
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Svalbard (Norway) as a terrestrial analogue for Martian landforms: Results on
- 2009
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In: EPSC Abstracts. European Planetary Science Congress. ; 4, EPSC2009-772
-
Conference paper (peer-reviewed)abstract
- Small alluvial fan-like landforms have been observed on Mars in association with recent gullies. Such fans are relatively small (km-scale) when compared to large alluvial fans on Mars, which can reach dimensions of tens of kilometers. The small fans are part of an erosion-transportsedimentation system (alcove-channel-apron). Morphologically very similar systems can be studied on Svalbard (Norway), which is a cold and dry polar desert and, therefore, a potentially useful terrestrial analogue for Mars` climate and climaterelated landforms. Here we give an update on our field work in summer 2008 and a simultaneous flight campaign with an airborne version (HRSCAX) of the High Resolution Stereo Camera (HRSC) onboard Mars Express. We also present very preliminary results from the field campaign in summer 2009.
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| 11. |
- Hellström, Mats, et al.
(author)
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Towards the development of a bioengineered uterus : Comparison of different protocols for rat uterus decellularization
- 2014
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In: Acta Biomaterialia. - : Elsevier BV. - 1742-7061 .- 1878-7568. ; 10:12, s. 5034-5042
-
Journal article (peer-reviewed)abstract
- Uterus transplantation (UTx) may be the only possible curative treatment for absolute uterine factor infertility, which affects 1 in every 500 females of fertile age. We recently presented the 6-month results from the first clinical UTx trial, describing nine live-donor procedures. This routine involves complicated surgery and requires potentially harmful immune suppression to prevent rejection. However, tissue engineering applications using biomaterials and stem cells may replace the need for a live donor, and could prevent the required immunosuppressive treatment. To investigate the basic aspects of this, we developed a novel whole-uterus scaffold design for uterus tissue engineering experiments in the rat. Decellularization was achieved by perfusion of detergents and ionic solutions. The remaining matrix and its biochemical and mechanical properties were quantitatively compared from using three different protocols. The constructs were further compared with native uterus tissue composition. Perfusion with Triton X-100/dimethyl sulfoxide/H2O led to a compact, weaker scaffold that showed evidence of a compromised matrix organization. Sodium deoxycholate/dH2O perfusion gave rise to a porous scaffold that structurally and mechanically resembled native uterus better. An innovative combination of two proteomic analyses revealed higher fibronectin and versican content in these porous scaffolds, which may explain the improved scaffold organization. Together with other important protocol-dependent differences, our results can contribute to the development of improved decellularization protocols for assorted organs. Furthermore, our study shows the first available data on decellularized whole uterus, and creates new opportunities for numerous in vitro and in vivo whole-uterus tissue engineering applications.
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| 12. |
- Johansson, Eva, et al.
(author)
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Evaluation of materials supply systems during product development projects
- 2006
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In: International Journal of Production Research. - : Informa UK Limited. - 0020-7543 .- 1366-588X. ; 44:5, s. 903-917
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Journal article (peer-reviewed)abstract
- The aim of this paper is to analyse how materials supply systems can be evaluated during product development projects in a concurrent engineering context. The focus is on performance assessment of materials supply systems and the input data required. A case study was conducted in close cooperation with a company and two performance measures were assessed during the concept definition phase and recalculated during the product and process validation phase. The results show that preliminary input data can be used to calculate performance measures by means of the following approaches: indicators, standards or scenarios. Furthermore, it is discussed how performance assessment can assist the materials supply systems design process in a concurrent engineering context by facilitating early problem discovery, early decision-making, and common understanding.
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| 13. |
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| 14. |
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| 15. |
- Johansson, Eva, et al.
(author)
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Materials supply systems design in product development projects
- 2006
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In: International Journal of Operations & Production Management. - : Emerald. - 0144-3577 .- 1758-6593. ; 26:4, s. 371-393
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Journal article (peer-reviewed)abstract
- Purpose: This research aims to develop a model for describing and analysing materials supply systems design in product development projects.Design/methodology/approach: Literature on materials supply and production systems design is reviewed in order to derive a materials supply systems design model. The model is applied to empirical data from a qualitative case study, which exemplifies how the model can serve to describe materials supply systems design in product development projects. Moreover, the model is used to analyse the empirical data related to the focus and characteristics of the design issues.Findings: The model developed contains the six areas: materials feeding, storage, transportation, handling, packaging, and manufacturing planning and control at four levels: supply chain, plant, subunit, and utility.Research limitations/implications: Future research could complement the model by developing a design process to enable systematic design of the materials supply system as well as the integration of materials supply aspects at an early stage of product development projects. Such a design process should also consider the design of the flows of specific components.Practical implications: The importance of considering the relations between the six design areas as well as evaluating the whole materials supply system is highlighted.Originality/value: The paper focuses on the materials supply aspects dealt with in product development projects, which have been the subject of little research interest so far, despite the fact that extensive resources are required for materials supply activities.
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| 16. |
- Johansson, Eva, 1969, et al.
(author)
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The information gap between design engineering and materials supply system design
- 2003
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In: Paper presented at The 17th International Conference on Production Research ICPR-17, Blacksburg, Virginia, 2003..
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Conference paper (other academic/artistic)abstract
- This paper focuses on the design of materials supply systems in product development projects. In order to design the materials supply system in parallel with the product, product data have to be made available to the materials supply system designers. The aim of this paper is to discuss the information quality of the product data needed and to indicate how the information quality can be increased. Empirical data have been gathered through case studies conducted within the Manufacturing Industry.The empirical data show many imperfections in the information quality. In order to increase the information quality, the possibilities given by PDM-systems must be utilised. It is also essential that the materials supply system designers are able to claim what product data they need and in what form they need them. In addition, the current status of the product data must be given, i.e. information about how much the data may change.Keywords: Materials supply systems design; Product development project; Concurrent engineering; Information quality; Product data; Product data management system.
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| 17. |
- Johansson, Eva, et al.
(author)
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The information gap between design engineering and materials supply systems design
- 2004
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In: International Journal of Production Research. - : Informa UK Limited. - 0020-7543 .- 1366-588X. ; 42:17, s. 3787-3801
-
Journal article (peer-reviewed)abstract
- This paper focuses on the design of materials supply systems in product development projects. In order to design the materials supply system in parallel with the product, product data must be available to the materials supply systems designers. The aim of this paper is to analyse the information quality of the required product data and to indicate how this information quality can be increased. Empirical data have been gathered through case studies conducted within the Manufacturing Industry. The empirical data show that it is possible to identify the product data required for materials supply systems design. It is also shown that there is an information gap between design engineering and materials supply systems design. The information quality of the required product data for the materials supply systems design has many imperfections, mainly in terms of accessibility, ease of operation, timeliness, understandability, interpretability, relevancy, and completeness. The information quality can be improved by the use of PDM systems, which are especially useful for facilitating an increase in accessibility, ease of operation, and timeliness.
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| 18. |
- Johansson, Gun-Britt, 1956-
(author)
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Synderskan och lagen: Barnamord i tre Norrlandslän 1830-1870
- 2006
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Doctoral thesis (other academic/artistic)abstract
- ABSTRACTMany studies have been conducted on infanticide and child homicide. Researchers have approached the subject with different theoretical frameworks and explored it from different dimensions, geographical areas, and time periods. As much as the questions have varied so have the answers. This study contributes to greater clarity on the causes of infanticide. Despite numerous studies on the subject, there is still no consensus its causes. My aim has been to combine different strategies for understanding the subject. I have used material both from an aggregated level and from an individual level. The main question I sought to answer was whether social causes rather than individual factors force or trigger women to kill their newborn child? Court material also provides for an in-depth understanding of our history. The social sciences have frequently drawn sketches of the social world with big lines. These lines have been necessary and useful to point at large-scale transformations of civilisation and modernisation but, in terms of understanding real life, they can provide us with a foggy and even mistaken picture. When social scientists enter the historical archives and similar sources, we often blunder in its richness and variation. Society may, in any case, have always been complicated and the every day life for each person as well.My findings show that infanticide signals low tolerance. In general, the women did not want to kill their own children. Moreover, my findings, like the results of other studies before mine, demonstrate that women who carry out infanticide represent normal women. To my knowledge, there isn’t one study on infanticide that claims the women were not normal. Women who committed infanticide did so out of fear: fear of losing their social bonds. They killed their children if the existence of the bonds was endangered or threatened. Often social bonds were related to their work situation as maids in farming households. If they couldn’t stay in the household after having the baby, many women had no where else to go. Their parents – poor, elderly or deceased – were unable to help. Sometimes the social bonds were threatened by other factors, often related to the child’s father. If he was already married or had a close relation with the woman’s family, their relationship could in fact, break her bonds to her own family and other relatives. Some women already had an illegitimate child. With a child out of wedlock, they had a difficult time getting work and housing. If they got pregnant again and the father to the new child refused to marry her or to support the child, she could in fact lack any resources for handling the situation.Finally: the findings talk about honour and infanticide. It was always shameful to get a child out of wedlock. But demographic research from North of Sweden has shown that these children had almost the same chances of survival during their first year as legitimate children. Sexuality outside marriage was not respected but much discussion around honour was more related to how the women would manage with the child. In my findings, shame seems to be related to having no support. Extramarital relations were not accepted but people probably didn’t care to much about it as far as they managed on their own. Being rejected, helpless, not able to work and not able to take care of the child that was what shame was about.Keywords: Infanticide, child homicide, illegitimacy, social bonds, shame
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| 19. |
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| 20. |
- Johansson Hanse, Jan, 1954, et al.
(author)
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Musculoskeletal Symptoms, Ergonomic Aspects and Psychosocial Factors in Two Different Truck Assembly Concepts
- 1993
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In: International Journal of Industrial Ergonomics. - 1872-8219 .- 0169-8141. ; 12:1-2, s. 35-48
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Journal article (peer-reviewed)abstract
- The project was carried out as a multidisciplinary correlational study of two truck-axle assembly systems (System A and B). System A (the old system) could be characterized as an unpaced line assembly system, whereas the change to the new system, System B, involved a parallelized system with longer job cycle time. The study included all permanent assembly workers in the two systems (System A 17 workers, System B 28 workers). The purpose of this study was to evaluate the two systems with respect to ergonomic factors, psychosocial factors and self-reported musculoskeletal symptoms. The job cycles were studied by means of video observation. Each subject answered a questionnaire regarding musculoskeletal symptoms and physical and psychosocial environment. The assemblers in System B were more satisfied with the physical work environment (e.g. noise, air), but less satisfied with the psychosocial environment, and the period prevalence of musculoskeletal symptoms was not lower, compared with the assemblers in System A. Video observation techniques showed that deep forward flexion was less common, but that the work was more hand intense in System B. In System B, neck/shoulder symptoms were associated principally with physical work (load) variables, whereas low back symptoms were associated with psychosocial variables.
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| 21. |
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| 22. |
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| 23. |
- Johnsson, Andreas, 1977, et al.
(author)
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POSSIBLE FREEZE AND THAW LANDFROMS ON HIGH-LATITUDE SLOPES ON MARS: INSIGHTS FROM TERRESTRIAL ANALOGS IN SPITSBERGEN, SVALBARD.
- 2011
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In: 42nd Lunar and Planetary Science Conference. ; 42:2758
-
Conference paper (peer-reviewed)abstract
- Solifluction lobes are common slope features in Polar Regions on Earth where freeze and thaw processes occur. Mars is currently a cold and barren planet with its water resources locked up in ice caps, glaciers and ice-enriched permafrost. However, features resembling solifluction lobes have been observed on high-latitude slopes on Mars and in most, but not all, cases in close proximity to gullies. Lobes are found on steep inner crater walls and in planform they show striking resemblance to terrestrial solifluction lobes. These observations may point to a late phase in Mars history with transient melt water in local environments. In our study we have examined solifluction lobes on slopes in Svalbard in order to compare to the Martian lobate landforms. Specific questions we address are: how widely distributed are these lobate landforms on Mars and how do they relate to known ground-ice related landforms?
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| 24. |
- Johnsson, Andreas, 1977, et al.
(author)
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POSSIBLE FREEZE/THAW LANDFORMS ON MARTIAN SLOPES: USING SVALBARD ADVENT VALLEY AS AN ANALOGUE TO MARS.
- 2010
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In: Third European Conference on Permafrost. - 9788248100102 ; 2010, s. 58-58
-
Conference paper (other academic/artistic)abstract
- Stripes and gelifluction lobes are common slope features in polar regions on Earth where freeze and thaw processes occur. Mars is currently a cold and barren planet with its water resources locked up as ice caps and ice-rich permafrost. However, features resembling stripes and gelifluction lobes have been observed on high-latitude slopes on Mars and in most, but not all, cases in close proximity to gullies. Stripe width typically ranges from ~50 cm to 1.5 m, and their orientation is consistently down slope, although it can not be excluded that it sometimes slightly deviates from the steepest topographic gradient. Lobes are found on steep inner crater walls and display similar dimensions as terrestrial gelifluction lobes. These observations may point to a late phase in Mars history with transient melt water in local niches. In our study we have examined sorted and non-sorted stripes as well as gelifluction lobes on slopes in Svalbard in order to test the working hypothesis of a freeze and thaw origin of the Martian landforms.
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| 25. |
- Johnsson, Andreas, 1977, et al.
(author)
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THE ORIGIN OF STRIPE-LIKE PATTERNS ON MARTIAN GULLY SLOPES; USING SVALBARD ADVENT VALLEY AS A MARS ANALOGUE.
- 2010
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In: 41st Lunar and Planetary Science Conference. ; :1665
-
Conference paper (other academic/artistic)abstract
- Stripes are a common slope features in polar regions on Earth were active layer processes (freezing/thawing and gelifluction) occur. Their origin is most likely polygenic and closely related to frost crack plygons and sorted circles with the addition of a gravitational component. Stripes are either sorted or unsorted. Features resembling stripes have been observed on slopes on Mars with or without association with polygons. Due to the current temperature and pressure regime on Mars soil moisture and active layer processes are not likely to occur. However, in recent HiRISE images stripelike patterns can be observed in proximity to gullies . Stripe width typically ranges from ~50 cm to 1.5 m, and their orientation is consistently down slope, although it can not be excluded that it sometimes slightly deviates from the steepest topographic gradient. In our study we have examined sorted and nonsorted stripes on slopes in Svalbard in order to test the working hypothesis of an cryoturbation origin for the martian stripe-like patterns. In doing so we compare their morphological characteristics, settings, and slope to those on Mars.
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| 26. |
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| 27. |
- Kurdve, Martin, 1971, et al.
(author)
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Considerations when Modelling EV Battery Circularity Systems
- 2019
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In: Batteries. - : MDPI AG. - 2313-0105. ; 5:2
-
Journal article (peer-reviewed)abstract
- The electric vehicle market is expected to grow substantially in the coming years, which puts new requirements on the end-of-life phase and on the recycling systems. To a larger extent, the environmental footprint from these vehicles is related to raw material extraction and production, and, consequently, a material- and energy-efficient 3R system (reuse, remanufacturing, recycling) is urgently needed. The ability to understand and model the design and development of such a system therefore becomes important. This study contributes to this by identifying factors that affect 3R system design and performance, relating these factors to the various actors and processes of the system and categorising them according to time from implementation to impact. The above is achieved by applying a PEST analysis (political, economic, social and technological factors), differentiating between political, economic, social and technological factors. Data were gathered from literature, by interviews and by a number of workshops in the automotive industry and the 3R system and observations at meetings, etc. The study confirms some previous results on how vehicle battery 3R systems work and adds knowledge about the influencing factors, especially the timeframes and dynamics of the system, necessary for modelling the system and the influencing factors. For practitioners, the results indicate how to use appropriate models and which factors are most relevant to them.
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| 28. |
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| 29. |
- Reiss, Dennis, et al.
(author)
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MORPHOLOGIC AND MORPHOMETRIC COMPARISION OF GULLIES ON SVALBARD AND MARS.
- 2009
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In: 40th Lunar and Planetary Science Conference. ; :2362
-
Conference paper (other academic/artistic)abstract
- The morphology of gullies on Mars indi-cates that they were formed by the action of water. How-ever, it is not clear what the dominant gully forming process is. On Earth, gullies might have formed by the processes of overland flow or debris flows, or a combination of both. In this work we compare the morphologic and morphometric observations and measurements (slopes, depth-width ratios and sinuosities) of Martian gullies with terrestrial analogs from Svalbard, Norway, in order to constrain the formation process (fluvial and/or debris flow).
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| 30. |
- Reiss, Dennis, et al.
(author)
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Terrestrial gullies and debris-flow tracks on Svalbard as planetary analogs for Mars
- 2011
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In: The Geological Society of America, Special Paper. - : Geological Society of America. ; 483, s. 165-175
-
Journal article (peer-reviewed)abstract
- We compared the morphology of gully sedimentary fans on Svalbard as possible analogs to gullies on Mars in order to constrain whether fl uvial and/or debris-fl ow processes are predominantly responsible for the formation of Martian gullies. Our analysis is based on high-resolution imagery (High Resolution Stereo Camera [HRSC-AX], ~20 cm/pixel) acquired through a fl ight campaign in summer 2008 and ground truth during two expeditions in the summers of 2008 and 2009 in Svalbard, compared to highresolution satellite imagery (High Resolution Imaging Science Experiment [HiRISE], ~25 cm/pixel) from Mars. On Svalbard, fluvial and debris-fl ow processes are evident in the formation of gullies, but the morphological characteristics clearly show that the transport and sedimentation of eroded material are predominated by debris flows. Most investigated gullies on Mars lack clear evidence for debris-flow processes. The Martian gully fan morphology is more consistent with the deposition of small overlapping fans by multiple fluvial flow events. Clear evidence for debris flows on Mars was only found in one new location, in addition to a few previously published examples. The occurrence of debris-flow processes in the formation of Martian gullies seems to be rare and locally limited. If predominantly fl uvial processes caused the formation of gullies on Mars, then large amounts of water would have been required for their formation because of the relatively low sediment supply in stream and/or hyperconcentrated fl ows. Repeated seasonal or episodic snow deposition and melting during periods of higher obliquity in the recent past on Mars can best explain the formation of the gullies.
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| 31. |
- Reiss, Dennis, et al.
(author)
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TERRESTRIAL GULLIES ON SVALBARD AS PLANETARY ANALOGS FOR MARS
- 2010
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In: 41st Lunar and Planetary Science Conference. ; :2492
-
Conference paper (other academic/artistic)abstract
- Martian gullies resemble terrestrial gul-lies, which are formed by a combination of processes includ-ing mass wasting, overland flow and debris flows. The gullies on Mars show several morphologic features such as braided channels, multiple terraces, point bars and cutbanks, which indicate that fluvial processes were involved in their formation. However, it remains unclear whether fluvial processes or debris flows are dominating the formation of gullies on Mars. Debris flows are viscous slurry flows with water and fines as the interstitial fluid. The flowing mix-tures of fines, clastic debris and water has a relatively low water content (≤ 30 % water by weight). Stream flows and hyperconcentrated flows have a high water content and relatively low sediment supply (≥ 30 % water by weight). The morphologies of debris flows fans show typical fea-tures such as levées, lobes, snouts and debris plugs, which are not observed from purely fluvial processes. In this work we compare the morphology of terrestrial gully analogs from Svalbard with Martian gullies in order to constrain which formation process might be dominant on Mars, i.e. fluvial and/or debris flow processes.
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| 32. |
- Sjöström, Nils, 1955, et al.
(author)
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Relatives' Experiences of Mental Health Care, Family Burden and Family Stigma: Does Participation in Patient-Appointed Resource Group Assertive Community Treatment (RACT) Make a Difference?
- 2021
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In: Issues in Mental Health Nursing. - : Informa UK Limited. - 0161-2840 .- 1096-4673. ; 42:11, s. 1010-1019
-
Journal article (peer-reviewed)abstract
- The aim of this exploratory cross-sectional study was to investigate the experiences of relatives of individuals with severe mental illness with and without participation in patient-appointed Resource Group Assertive Community Treatment (RACT). A total of 139 relatives (79 with and 60 without RACT) completed the Family Involvement and Alienation Questionnaire, the Burden Inventory for Relatives of Persons with Psychotic Disturbances, and the family version of the Inventory of Stigmatizing Experiences. We found that relatives participating in RACT experienced a more positive approach from the healthcare professionals, as well as a lower degree of alienation from the provision of care. Relatives who did not participate in RACT were more afraid that their ill next of kin would hurt someone. No other differences in family burden were found. Experiences of family stigmatization were similar in both groups. In conclusion, participating in patient-appointed RACT may contribute to a higher level of satisfaction for relatives in their encounter with healthcare professionals and a more positive alliance. Implementation of RACT in new settings would require adaptation to local conditions to facilitate cooperation between healthcare staff and other relevant services. Staff training focuses on the case manager function and needs assessment, as well as how to create an alliance with the patient and his/her relatives.
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| 33. |
- Adlemo, Anders, 1957, et al.
(author)
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Fault tolerance strategies in an existing FMS installation
- 1993
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In: Control Engineering Practice. - 0967-0661. ; 1:1, s. 127-134
-
Journal article (peer-reviewed)abstract
- This paper describes a case study of an FMS installation in which fault tolerance is modelled through the use of a description model called the General Recursive System (GRS). The GRS makes it possible to study different system configuration are described, called Hardware Configuration, Mission Configuration and Work Configuration. Fault tolerance, i.e. ways to overcome erroneous situations in the FMS installation, is obtained by choosing alternative system configurations. Alternative ways to describe different fault tolerance strategies within the FMS installation are illustrated through examples.
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| 34. |
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| 35. |
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| 36. |
- Agrawal, Tarun, 1989, et al.
(author)
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Automating Loading and Unloading for Autonomous Transport: Identifying Challenges and Requirements with a Systems Approach
- 2023
-
In: IFIP Advances in Information and Communication Technology. - 1868-4238 .- 1868-422X. - 9783031436697 ; 691 AICT, s. 332-345
-
Conference paper (peer-reviewed)abstract
- The logistics industry has undergone significant changes due to high demand, competition, cost pressures, interruptions, and labor market limitations affecting supply chains. As a result, there has been a significant adoption of automation in internal logistics such as warehousing, stock control, and material handling, leading to increased organizational competitiveness by reducing manual labor costs and time spent on these operations. The use of autonomous road transport holds potential to improve transport performance within areas of safety, sustainability, and efficiency. However, for autonomous transport to be fully ealized, loading and unloading processes at shipping and receiving facilities must also be automated. This paper takes a systems approach to identify the challenges and requirements for automated loading and unloading in a setting of autonomous truck transport potentially within a production setting. By addressing these challenges and meeting the necessary requirements, it may be possible to fully realize the benefits of autonomous transport and improve overall transport performance.
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| 37. |
- Ahlsén, Bertil, et al.
(author)
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Ombyggnad Torslanda
- 1990
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Reports (other academic/artistic)abstract
- Consumer report for the company in question (the Volvo Automobile Company and the Volvo Torslanda plant) which is financed by the company and partly also by a research foundation. It is a matter of a work that in this particular case were carried out during nine years in a number of experimental workshops located outside the Chalmers University of Technology. These workshops were financed by the Volvo Automobile and Truck companies. This achievement, as the final contribution to the Swedish automotive industry after having already treated this research field/problem area for more than two decades before this particular period if time (involving several junior and senior research competencies, as well as industrial and governmental foundings).
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| 38. |
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| 39. |
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| 40. |
- Ambring, Anneli, 1964, et al.
(author)
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Effects of a Mediterranean-inspired diet on blood lipids, vascular function and oxidative stress in healthy subjects.
- 2004
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In: Clinical science (London, England : 1979). - 0143-5221. ; 106:5, s. 519-25
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Journal article (peer-reviewed)abstract
- Mediterranean-inspired diets have been shown to decrease cholesterol levels in patients with hypercholesterolaemia, who frequently exhibit endothelial dysfunction. The aims of the present study are to improve endothelial function by dietary intervention in healthy subjects with lipid levels representative of a Western population. Twenty-two healthy subjects (mean total cholesterol, 5.6 mmol/l) were given a Mediterranean-inspired diet rich in omega-3 fatty acids and sterol esters, but low in saturated fat, or an ordinary Swedish diet, for 4 weeks in a randomized cross-over study. The composition of the diets were: in the Swedish diet, 2090 kcal (where 1 kcal=4.184 kJ; 48% of energy from carbohydrate, 15% from protein and 36% from fat) and 19 g of fibre; in the Mediterranean-inspired diet, 1869 kcal (48% of energy from carbohydrate, 16% from protein, 34% from fat) and 40 g of fibre. After each dietary period, fasting blood lipids, insulin and glucose levels, as well as apo B (apolipoprotein B) and LDL (low-density lipoprotein) particle size, were analysed. Endothelial-dependent and -independent vasodilation was measured invasively by venous occlusion plethysmography, and arterial distensibility was assessed by echocardiography tracking. Fibrinolytic capacity across the forearm, as well as oxidative stress measured through urinary F(2)-isoprostane, were evaluated. Total, LDL- and apo B-cholesterol and triacylglycerol (triglyceride) concentrations were decreased by 17%, 22%, 16% and 17% respectively, after the Mediterranean-inspired diet compared with the Swedish diet ( P <0.05 for all). However, no differences in plasma concentrations of insulin and glucose and LDL particle size, endothelial function, arterial distensibility, fibrinolytic capacity or oxidative stress were detected. Treatment for 4 weeks with a Mediterranean-inspired diet decreased blood lipids in healthy individuals with a low-risk profile for cardiovascular disease. This beneficial effect was not mirrored in vascular function or oxidative stress evaluation.
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| 41. |
- Ambring, Anneli, 1964, et al.
(author)
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Mediterranean-inspired diet lowers the ratio of serum phospholipid n-6 to n-3 fatty acids, the number of leukocytes and platelets, and vascular endothelial growth factor in healthy subjects.
- 2006
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In: The American journal of clinical nutrition. - 0002-9165. ; 83:3, s. 575-81
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Journal article (peer-reviewed)abstract
- BACKGROUND: Reduced cardiovascular mortality and morbidity have been shown in persons adhering to Mediterranean-inspired diets (MIDs). Although the underlying mechanisms of this association are poorly understood, the importance of increasing dietary amounts of polyunsaturated fatty acids of the n-3 series has been emphasized. OBJECTIVE: We investigated whether a MID provided to healthy subjects would affect 1) the inflammatory process and endothelial indexes such as vasoregulation and vascular endothelial growth factor (VEGF) and 2) serum phospholipid fatty acid composition. DESIGN: A total of 22 subjects (10 women) received a MID or an ordinary Swedish diet (OSD) for 4 wk in a crossover fashion. Concentrations of lipids and fatty acids, high-sensitivity C-reactive protein, and interleukin 6, both before and after lipopolysaccharide stimulation; the number of leukocytes and platelets; and VEGF and monocyte chemoattractant protein 1 were analyzed. RESULTS: The plasma ratio of n-6 to n-3 fatty acids was substantially lower after the MID than after the OSD (x +/- SEM: 4.72 +/- 0.19 and 2.60 +/- 0.17, respectively; P < 0.0001). Neither C-reactive protein nor interleukin 6 concentrations changed significantly after the MID compared with the OSD. The total number of leukocytes and platelets was 10% (P < 0.05) and 15% (P < 0.001) lower, respectively, after the MID than after the OSD. Serum VEGF concentrations were lower after the MID than after the OSD (237 +/- 30 and 206 +/- 25 pg/mL, respectively; P = 0.0014). CONCLUSIONS: A MID reduces the number of platelets and leukocytes and VEGF concentrations in healthy subjects. This may be linked to higher serum concentrations of n-3 fatty acids, which promote a favorable composition of phospholipids.
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| 42. |
- Ander, Mats, 1964, et al.
(author)
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Development, accomplishment and evaluation of a project course in applied mechanics---Lessons learnt
- 2009
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In: Svenska mekanikdagarna, Södertälje 2009, 15-17-juni, Session 7:4-Utbildning, sid 99 (1 page abstract). ; , s. 99-
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Conference paper (other academic/artistic)abstract
- Development, accomplishment and evaluation of a project course in applied mechanics---Lessons learnt M. Ander , T. Grönstedt, T. Abrahamsson and G. JohanssonThis presentation concerns teaching and learning from working in projects within the Chalmers Master programme in Solid and fluid mechanics. The academic tradition requires teaching solid and fluid mechanics as separated subjects of applied mechanics. The researchers/teachers and students belonging to either discipline do not meet on daily basis and thus two separate cultures develop; CFD for fluids and FEM for solids.However, in industry today fresh engineers will meet challenges in multidisciplinary problems and they are expected to be able to know how to treat them. As a remedy to better prepare for their engineering profession, a project course in applied mechanics has been developed. The outline of the course follows the CDIO[1] learning approach: Conceive, Design, Implement and Operate. Starting off from back of the envelope calculations, where all students are required to address all disciplines, the project proceeds towards distinct specializations. The students, divided into groups of six to seven members, focus on ‘student specialists’ roles in solid/structural mechanics-FEM, fluid dynamics, and experimental modal analysis EMA, simulating a true multidisciplinary working environment. The projects studied incorporate a fluid structure interaction core problem, but are required to pose challenges within each specialisation. The task is formulated as a competition to find better solutions or as an investigation of existing methods to solve a problem at hand. The examination is based on individual assignments, group work, presentation of a final report and opposition. As resources for analysing the problems, the students have access to wind tunnel testing, EMA-equipment, computer rooms with commercial software for CFD and FEM. This year we have introduced the ANSYS workbench as a common platform for fluid–structure interaction simulations, allowing the teams to work more closely together. The student perspective is dominated by the urge to approach real world problems with industrial tools. A better contact and understanding between students as well as between teachers/researchers in the different disciplines of applied mechanics are achieved by this approach. Some outstanding challenges are the limited time frame of the course, the time consuming communication required within the teachers team and the student frustration arising from having to address open end problems. [1]www.cdio.org
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| 43. |
- Andersson, Dan, 1966, et al.
(author)
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Transport service procurement – initial findings and a research agenda
- 2016
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In: 25th IPSERA Conference, Dortmund, March 20-23, 2016..
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Conference paper (peer-reviewed)abstract
- Technology alone will not be sufficient to cope with emission reduction challenges. Transport procurement requires attention for individual firms as well as the transport industry to tackle environmental challenges. The aim of this paper is to identify practice, perceptions and outlook of transport buyers in order to present a research agenda that informs the advancement of current practice, on the basis of surveys, capturing practice among Swedish transport buyers. The direction for future research comprise levels of analysis ranging from the service level to industry-level, and suggest a mixed-method, wherein surveys are combined with in-depth case studies and workshops.
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| 44. |
- Arnäs, Per-Olof, 1969, et al.
(author)
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NOFOMA 2013
- 2014
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In: International Journal of Physical Distribution and Logistics Management. - 0960-0035. ; 44:4
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Journal article (peer-reviewed)
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| 45. |
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| 46. |
- Bergquist, Filip, 1970, et al.
(author)
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Motor Efficacy of Subcutaneous DIZ102, Intravenous DIZ101 or Intestinal Levodopa/Carbidopa Infusion
- 2024
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In: MOVEMENT DISORDERS CLINICAL PRACTICE. - 2330-1619.
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Journal article (peer-reviewed)abstract
- Background: It has been suggested that carbidopa at high blood concentrations may counter the therapeutic effect of levodopa in Parkinson's disease by entering the brain and blocking central levodopa conversion to dopamine. We previously demonstrated equivalent plasma levodopa concentration in patients with Parkinson's disease during 16 h of (1) intravenous carbidopa/levodopa (DIZ101) infusion, (2) subcutaneous carbidopa/levodopa (DIZ102) infusion or (3) intestinal carbidopa/levodopa gel infusion. Plasma levels of carbidopa were however approximately four times higher with DIZ101 and DIZ102 than with LCIG, and higher than those usually observed with oral levodopa/carbidopa. Objectives: To investigate if high carbidopa blood concentrations obtained with parenteral levodopa/carbidopa (ratio 8:1) counter the effect of levodopa on motor symptoms. Methods: Eighteen patients with advanced Parkinson's disease were administered DIZ101, DIZ102, and intestinal levodopa/carbidopa gel for 16 h on different days in randomized order. Video recordings of a subset of the motor examination in the Unified Parkinson's Disease Rating Scale (UPDRS) were evaluated by raters blinded for treatment and time. Motor function was also measured using a wrist-worn device monitoring bradykinesia, dyskinesia, and tremor (Parkinson KinetiGraph). Results: There was no tendency for poorer levodopa effect with DIZ101 or DIZ102 as compared to LCIG. Conclusion: Although DIZ101 or DIZ102 causes approximately four times higher plasma carbidopa levels than LCIG, patients responded equally well to all treatments. The results do not indicate that high plasma carbidopa levels hamper the motor efficacy of levodopa.
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| 47. |
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| 48. |
- Borenäs, Marcus, et al.
(author)
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ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition
- 2024
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In: Proceedings of the National Academy of Sciences of the United States of America. - 1091-6490. ; 121:1
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Journal article (peer-reviewed)abstract
- High-risk neuroblastoma (NB) is a significant clinical challenge. MYCN and Anaplastic Lymphoma Kinase (ALK), which are often involved in high-risk NB, lead to increased replication stress in cancer cells, suggesting therapeutic strategies. We previously identified an ATR (ataxia telangiectasia and Rad3-related)/ALK inhibitor (ATRi/ALKi) combination as such a strategy in two independent genetically modified mouse NB models. Here, we identify an underlying molecular mechanism, in which ALK signaling leads to phosphorylation of ATR and CHK1, supporting an effective DNA damage response. The importance of ALK inhibition is supported by mouse data, in which ATRi monotreatment resulted in a robust initial response, but subsequent relapse, in contrast to a 14-d ALKi/ATRi combination treatment that resulted in a robust and sustained response. Finally, we show that the remarkable response to the 14-d combined ATR/ALK inhibition protocol reflects a robust differentiation response, reprogramming tumor cells to a neuronal/Schwann cell lineage identity. Our results identify an ability of ATR inhibition to promote NB differentiation and underscore the importance of further exploring combined ALK/ATR inhibition in NB, particularly in high-risk patient groups with oncogene-induced replication stress.
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| 49. |
- Browne, Michael, et al.
(author)
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MIND THE GAP: THE INTERFACE BETWEEN AUTONOMOUS VEHICLES AND THE LOGISTICS SYSTEM
- 2020
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Conference paper (other academic/artistic)abstract
- Purpose Using autonomous vehicles in goods transport has potential benefits. However, the transition to a future autonomous (and electric) freight system needs to take account of the interface between the vehicle and other parts of the logistics system in order to exploit potential benefits and overcome challenges related to the absence of a driver. The purpose of the research is to identify the prerequisites for achieving automated loading, unloading, related information handling and in-plant transport at these interfaces. Research Approach Cases studies consider senders and receivers of various products as well as organisations that have a role including real estate companies that develop warehouses and terminals. The case studies consider vehicle and handling equipment technology alongside the processes that may need to change if the efficiency gains of an autonomous vehicle are to be realised. Research questions are addressed at the logistics system level. The cases studies combine questions about logistics process and technology alongside those concerned with underlying business models. Findings and Originality Results presented are at the half way stage of a two-year project and will be based on the initial series of interviews for four case studies. Findings so far include: (1) lack of development in this topic compared with interest in autonomous and automated transport (2) importance of organisational ssues in the logistics chain e.g. contractual relationships (3) importance of taking a broad view of the companies that need to be involved (4) product type and characteristics are important but other factors may have more influence on the scope to develop initiatives in this area. Research Impact The research provides insights into the complexity of the interfaces in autonomous and automated transport and logistics systems. The empirical findings enrich the discussion of this field. Combining insights from logistics, technology, materials handling and business has demonstrated the benefits of an interdisciplinary approach. Practical Impact Autonomous transport systems may bring many commercial benefits. However, the scale of these benefits will be significantly diminished if questions about the interface points in the logistics system are not addressed. The outputs of the research will provide important insights for managers addressing these challenges.
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| 50. |
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