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1.
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2.
  • Beal, Jacob, et al. (author)
  • Robust estimation of bacterial cell count from optical density
  • 2020
  • In: Communications Biology. - : Springer Science and Business Media LLC. - 2399-3642. ; 3:1
  • Journal article (peer-reviewed)abstract
    • Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data.
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3.
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4.
  • Klionsky, Daniel J., et al. (author)
  • Guidelines for the use and interpretation of assays for monitoring autophagy
  • 2012
  • In: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 8:4, s. 445-544
  • Research review (peer-reviewed)abstract
    • In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. A key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process vs. those that measure flux through the autophagy pathway (i.e., the complete process); thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated from stimuli that result in increased autophagic activity, defined as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (in most higher eukaryotes and some protists such as Dictyostelium) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the field understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field.
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5.
  • Luo, Yifei, et al. (author)
  • Technology Roadmap for Flexible Sensors
  • 2023
  • In: ACS Nano. - : American Chemical Society. - 1936-0851 .- 1936-086X. ; 17:6, s. 5211-5295
  • Research review (peer-reviewed)abstract
    • Humans rely increasingly on sensors to address grand challenges and to improve quality of life in the era of digitalization and big data. For ubiquitous sensing, flexible sensors are developed to overcome the limitations of conventional rigid counterparts. Despite rapid advancement in bench-side research over the last decade, the market adoption of flexible sensors remains limited. To ease and to expedite their deployment, here, we identify bottlenecks hindering the maturation of flexible sensors and propose promising solutions. We first analyze challenges in achieving satisfactory sensing performance for real-world applications and then summarize issues in compatible sensor-biology interfaces, followed by brief discussions on powering and connecting sensor networks. Issues en route to commercialization and for sustainable growth of the sector are also analyzed, highlighting environmental concerns and emphasizing nontechnical issues such as business, regulatory, and ethical considerations. Additionally, we look at future intelligent flexible sensors. In proposing a comprehensive roadmap, we hope to steer research efforts towards common goals and to guide coordinated development strategies from disparate communities. Through such collaborative efforts, scientific breakthroughs can be made sooner and capitalized for the betterment of humanity.
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6.
  • 2019
  • Journal article (peer-reviewed)
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7.
  • Ablikim, M., et al. (author)
  • Amplitude analysis of the D+ -> K-S(0)pi + (0)(pi) Dalitz plot
  • 2014
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 89:5, s. 052001-
  • Journal article (peer-reviewed)abstract
    • We perform an analysis of the D+ -> K-S(0)pi + (0)(pi) Dalitz plot using a data set of 2.92 fb(-1) of e(+) e(-) collisions at the (3770) mass accumulated by the BESIII experiment, in which 166694 candidate events are selected with a background of 15.1%. The Dalitz plot is found to be well represented by a combination of six quasitwo- body decay channels [k(SP)(0)(+) (1450)(+,) ] plus a small nonresonant component. Using the fit fractions from this analysis, partial branching ratios are updated with higher precision than previous measurements.
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8.
  • Ablikim, M., et al. (author)
  • Amplitude analysis of the KSKS system produced in radiative J /psi decays
  • 2018
  • In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 98:7
  • Journal article (peer-reviewed)abstract
    • An amplitude analysis of the KSKS system produced in radiative J/psi decays is performed using the (1310.6 +/- 7.0) x 10(6) nip decays collected by the BESIII detector. Two approaches are presented. A mass-dependent analysis is performed by parametrizing the KSKS invariant mass spectrum as a sum of Breit-aligner line shapes. Additionally, a mass-independent analysis is performed to extract a piecewise function that describes the dynamics of the KSKS system while making minimal assumptions about the properties and number of poles in the amplitude. The dominant amplitudes in the mass-dependent analysis include the f(0)(1710), f(0)(2200), and f(2)'(1525). The mass-independent results, which are made available as input for further studies, are consistent with those of the mass-dependent analysis and are useful for a systematic study of hadronic interactions. The branching fraction of radiative J/psi decays to KSKS is measured to be (8.1 +/- 0.4) x 10(-4), where the uncertainty is systematic and the statistical uncertainty is negligible.
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9.
  • Ablikim, M., et al. (author)
  • Amplitude analysis of the pi(0)pi(0) system produced in radiative J/psi decays
  • 2015
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 92:5
  • Journal article (peer-reviewed)abstract
    • An amplitude analysis of the pi(0)pi(0) system produced in radiative J/psi decays is presented. In particular, a piecewise function that describes the dynamics of the pi(0)pi(0) system is determined as a function of M pi(0)pi(0) from an analysis of the (1.311 +/- 0.011) x 10(9) J/psi decays collected by the BESIII detector. The goal of this analysis is to provide a description of the scalar and tensor components of the pi(0)pi(0) system while making minimal assumptions about the properties or number of poles in the amplitude. Such a model-independent description allows one to integrate these results with other related results from complementary reactions in the development of phenomenological models, which can then be used to directly fit experimental data to obtain parameters of interest. The branching fraction of J/psi -> pi(0)pi(0) is determined to be (1.15 +/- 0.05) x 10(-3), where the uncertainty is systematic only and the statistical uncertainty is negligible.
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10.
  • Ablikim, M., et al. (author)
  • Dark photon search in the mass range between 1.5 and 3.4 GeV/c
  • 2017
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 774, s. 252-257
  • Journal article (peer-reviewed)abstract
    • Using a data set of 2.93 fb taken at a center-of-mass energy root s = 3.773 GeV with the BESIII detector at the BEPCII collider, we perform a search for an extra U(1) gauge boson, also denoted as a dark photon. We examine the initial state radiation reactions e(+)e(-) -> e(+)e(-) gamma(ISR) and e(+)e(-) -> mu(+)mu(-) gamma(ISR) for this search, where the dark photon would appear as an enhancement in the invariant mass distribution of the leptonic pairs. We observe no obvious enhancement in the mass range between 1.5 and 3.4 GeV/c(2) and set a 90% confidence level upper limit on the mixing strength of the dark photon and the Standard Model photon. We obtain a competitive limit in the tested mass range.
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11.
  • Ablikim, M., et al. (author)
  • Measurement of chi(cJ) decaying into eta ' K+K-
  • 2014
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 89:7, s. 074030-
  • Journal article (peer-reviewed)abstract
    • Using (106.41 +/- 0.86) x 10(6) Psi(3686) events collected with the BESIII detector at BEPCII, we study for the first time the decay chi(cJ) -> eta'K+K- (J = 1, 2), where eta' -> gamma rho(0) and eta' -> eta pi(+)pi(-). A partial wave analysis in the covariant tensor amplitude formalism is performed for the decay chi(c1) -> eta'K+K-. Intermediate processes chi(c1) -> eta'f(2)'(1525) chi(c1) -> K-0*(1430)K-+/-(-/+) (K-0*(1430)(+/-) -> eta'K-+/-) are observed with statistical significances larger than 5 sigma, and their branching fractions are measured.
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12.
  • Ablikim, M., et al. (author)
  • Measurement of e(+)e(-) -> K(K)over-barJ/psi cross sections at center-of-mass energies from 4.189 to 4.600 GeV
  • 2018
  • In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 97:7
  • Journal article (peer-reviewed)abstract
    • We investigate the process e(+)e(-) -> K (K) over barJ/psi at center-of-mass energies from 4.189 to 4.600 GeV using 4.7 fb(-1) of data collected by the BESIII detector at the BEPCII collider. The Born cross sections for the reactions e(+)e(-) -> K(+)K(-)J/psi and K(S)(0)K(S)(0)J/psi are measured as a function of center-of-mass energy. The energy dependence of the cross section for e(+)e(-) -> K(+)K(-)J/psi is shown to differ from that for pi(+)pi(-)J/psi in the region around the Y(4260). In addition, there is evidence for a structure around 4.5 GeV in the e(+)e(-) -> K(+)K(-)J/psi cross section that is not present in pi(+)pi(-)J/psi.
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13.
  • Ablikim, M., et al. (author)
  • Measurement of e(+)e(-) -> pi(+)pi(-) psi(3686) from 4.008 to 4.600 GeV and observation of a charged structure in the pi(+/-)psi(3686) mass spectrum
  • 2017
  • In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:3
  • Journal article (peer-reviewed)abstract
    • We study the process e(+)e(-) -> p(+)p(-)psi(3686) using 5.1 fb(-1) of data collected at 16 center-of-mass energy (root s) points from 4.008 to 4.600 GeV by the BESIII detector operating at the BEPCII collider. The measured Born cross sections for e(+)e(-) -> p(+)p(-)psi(3686) are consistent with previous results, but with much improved precision. A fit to the cross section shows contributions from two structures: the first has M = 4209.5 +/- 7.4 +/- 1.4 MeV/c(2) and Gamma = 80.1 +/- 24.6 +/- 2.9 MeV, and the second has M = 4383.8 +/- 4.2 +/- 0.8 MeV/c(2) and Gamma = 84.2 +/- 12.5 +/- 2.1 MeV, where the first errors are statistical and the second systematic. The lower-mass resonance is observed in the process e(+)e(-) -> p(+)p(-)psi(3686) for the first time with a statistical significance of 5.8 sigma. A charged charmoniumlike structure is observed in the pi(+/-)psi(3686) invariant mass spectrum for data at root s = 4.416 GeV. A fit with an S-wave Breit-Wigner function yields a mass M = 4032.1 +/- 2.4 MeV/c(2), where the errors are statistical only. However, there are still unresolved discrepancies between the fit model and data. The width of the intermediate state varies in a wide range for different kinematic regions within the data set. Therefore, no simple interpretation of the data has been found, and a future data sample with larger statistics and more theoretical input will be required to better understand this issue.
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14.
  • Ablikim, M., et al. (author)
  • Measurement of singly Cabibbo-suppressed decays D-0 → π0π0π0, π0π0η, π0ηη and ηηη
  • 2018
  • In: Physics Letters B. - : ELSEVIER SCIENCE BV. - 0370-2693 .- 1873-2445. ; 781, s. 368-375
  • Journal article (peer-reviewed)abstract
    • Using a data sample of e(+)e(-) collision data corresponding to an integrated luminosity of 2.93 fb(-1) collected with the BESIII detector at a center-of-mass energy of root s = 3.773 GeV, we search for the singly Cabibbo-suppressed decays D-0 -> pi(0)pi(0)pi(0), pi(0)pi(0)eta, pi(0)eta eta and eta eta eta using the double tag method. The absolute branching fractions are measured to be B(D-0 -> pi(0)pi(0)pi(0)) = (2.0 +/- 0.4 +/- 0.3) x 10(-4), B(D-0 -> pi(0)pi(0)eta) = (3.8 +/- 1.1 +/- 0.7) x 10(-4) and B(D-0 -> pi(0)eta eta) = (7.3 +/- 1.6 +/- 1.5) x 10(-4) with the statistical significances of 4.8 sigma, 3.8 sigma and 5.5 sigma, respectively, where the first uncertainties are statistical and the second ones systematic. No significant signal of D-0 -> eta eta eta is found, and the upper limit on its decay branching fraction is set to be B(D-0 -> eta eta eta) < 1.3 x 10(-4) at the 90% confidence level.
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15.
  • Ablikim, M., et al. (author)
  • Measurement of the absolute branching fraction of D*(s0) (2317)(+/-) -> pi D-0(s)+/-
  • 2018
  • In: Physical Review D. - : American Physical Society. - 2470-0010 .- 2470-0029. ; 97:5
  • Journal article (peer-reviewed)abstract
    • The process e(+)e(-) -> D*D-+(s)*(s0) (2317)(-) + c.c. is observed for the first time with the data sample of 567 pb(-1) collected with the BESIII detector operating at the BEPCII collider at a center-of-mass energy root s = 4.6 GeV. The statistical significance of the D*(s0) (2317)(+/-) signal is 5.8 sigma and the mass is measured to be (2318.3 +/- 1.2 +/- 1.2) MeV/c(2). The absolute branching fraction B(D*(s0) (2317)(+/-) -> pi D-0(s)+/-) is measured as 1.00(-0.14)(+0.00) (stat)(-0.14)(+0.00) (syst) for the first time. The uncertainties are statistical and systematic, respectively.
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16.
  • Ablikim, M., et al. (author)
  • Measurement of the Absolute Branching Fraction of the Inclusive Decay Lambda(+)(c) -> Lambda plus X
  • 2018
  • In: Physical Review Letters. - : AMER PHYSICAL SOC. - 0031-9007 .- 1079-7114. ; 121:6
  • Journal article (peer-reviewed)abstract
    • Based on an e(+)e(-) collision data sample corresponding to an integrated luminosity of 567 pb(-1) taken at the center-of-mass energy of root s = 4.6 GeV with the BESIII detector, we measure the absolute branching fraction of the inclusive decay Lambda(+)(c) -> Lambda + X to be B(Lambda(+)(c) -> Lambda + X) = (38.2(-2.2)(+2.8) +/- 0.9)% using the double-tag method, where X refers to any possible final state particles. In addition, we search for direct CP violation in the charge asymmetry of this inclusive decay for the first time, and obtain A(CP) [B(Lambda(+)(c) -> Lambda + X) - B((Lambda) over bar (-)(c) -> (Lambda) over bar + X)]/[B(Lambda(+)(c) -> Lambda + X) + B((Lambda) over bar (-)(c) -> (Lambda) over bar + X)] = (2.1(-6.6)(+7.0) +/- 1.6)%, a statistically limited result with no evidence of CP violation.
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17.
  • Ablikim, M., et al. (author)
  • Measurement of the branching fraction for psi(3686) -> omega K+K-
  • 2014
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 89:11, s. 112006-
  • Journal article (peer-reviewed)abstract
    • With 1.06 x 10(8) psi(3686) events collected with the BESIII detector, the branching fraction of psi(3686) -> omega K+K- is measured to be (1.54 +/- 0.04 +/- 0.11) x 10(-4). This is the most precise result to date, due to the largest psi(3686) sample, improved signal reconstruction efficiency, good simulation of the detector performance, and a more accurate knowledge of the continuum contribution. Using the branching fraction of J/psi -> omega K+K-, the ratio B(psi(3868) -> K+K-)/B(J/psi -> K+K-) is determined to be (18.4 +/- 3.7)%. This constitutes a significantly improved test of the 12% rule, with the uncertainty now dominated by the J/psi branching fraction.
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18.
  • Ablikim, M., et al. (author)
  • Measurement of the branching fractions of D-s(+) -> eta ' X and D-s(+) -> eta 'rho(+) in e(+)e(-) -> Ds+Ds-
  • 2015
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 750, s. 466-474
  • Journal article (peer-reviewed)abstract
    • We study D-s(+) decays to final states involving the eta' with a 482 pb(-1) data sample collected at root s = 4.009 GeV with the BESIII detector at the BEPCII collider. We measure the branching fractions B(D-s(+) -> eta'X) = (8.8 +/- 1.8 +/- 0.5)% and B(D-s(+) > eta'rho(+)) = (5.8 +/- 1.4 +/- 0.4)% where the first uncertainty is statistical and the second is systematic. In addition, we estimate an upper limit on the non-resonant branching ratio B(D-s(+) -> eta'pi(+)pi(0)) < 5.1% at the 90% confidence level. Our results are consistent with CLEO's recent measurements and help to resolve the disagreement between the theoretical prediction and CLEO's previous measurement of B(D-s(+) -> eta'rho(+)).
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19.
  • Ablikim, M., et al. (author)
  • Measurement of the leptonic decay width of J/psi using initial state radiation
  • 2016
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 761, s. 98-103
  • Journal article (peer-reviewed)abstract
    • Using a data set of 2.93 fb(-1) taken at a center-of-mass energy of root s = 3.773 GeV with the BESIII detector at the BEPCII collider, we measure the process e(+) e(-) -> J/psi gamma -> mu(+)mu(-)gamma and determine the product of the branching fraction and the electronic width B-mu mu . Gamma(ee) = (333.4 +/- 2.5(stat) +/- 4.4(sys)) eV. Using the earlier-published BESIII result for B-mu mu = (5.973 +/- 0.007(stat) +/- 0.037(sys))%, we derive the J/psi electronic width Gamma(ee) = (5.58 +/- 0.05(stat) +/- 0.08(sys)) keV. (C) 2016 The Author(s). Published by Elsevier B.V.
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20.
  • Ablikim, M., et al. (author)
  • Measurement of the matrix elements for the decays eta -> pi(+)pi(-)pi(0) and eta/eta ' -> pi(0)pi(0)pi(0)
  • 2015
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 92:1
  • Journal article (peer-reviewed)abstract
    • Based on a sample of 1.31 x 10(9) J/psi events collected with the BESIII detector at the BEPCII collider, Dalitz plot analyses of selected 79,625 eta -> pi(+)pi(-)pi(0) events, 33,908 eta -> pi(0)pi(0)pi(0) events, and 1,888 eta' -> pi(0)pi(0)pi(0) events are performed. The measured matrix elements of eta -> pi(+)pi(-)pi(0) are in reasonable agreement with previous measurements. The Dalitz plot slope parameters of eta -> pi(0)pi(0)pi(0) and eta' -> pi(0)pi(0)pi(0) are determined to be -0.055 +/- 0.014 +/- 0.004 and -0.640 +/- 0.046 +/- 0.047, respectively, where the first uncertainties are statistical and the second systematic. Both values are consistent with previous measurements, while the precision of the latter one is improved by a factor of 3. Final state interactions are found to have an important role in those decays.
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21.
  • Ablikim, M., et al. (author)
  • Measurements of absolute branching fractions for D mesons decays into two pseudoscalar mesons
  • 2018
  • In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 97:7
  • Journal article (peer-reviewed)abstract
    • Using a data sample of e(+)e(-) collision data with an integrated luminosity of 2.93 fb(-1) taken at the center-of-mass energy root s = 3.773 GeV with the BESIII detector operating at the BEPCII storage rings, we measure the absolute branching fractions of the two-body hadronic decays D+ -> pi(+)pi(0), K+pi(0), pi(+)eta., K+eta., pi(+)eta', K+eta', K-S(0)pi(+), (KSK+)-K-0, and D-0 -> pi(+)pi(-), K+ K-, K--/+pi(+/-), K-S(0)pi(0), K-S(0)eta, K-S(0)eta' Our results are consistent with previous measurements within uncertainties. Among them, the branching fractions for D+-> pi(+)pi(0), K+pi(0), pi(+)eta, pi(+)eta', (KSK+)-K-0, (KSK+)-K-0 and D-0 -> K-S(0)pi(0), K-S(0)eta, K-S(0)eta' are determined with improved precision compared to the world average values.
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22.
  • Ablikim, M., et al. (author)
  • Measurements of the branching fractions of the singly Cabibbo-suppressed decays D0→ωη, η(')π0 and η(')η
  • 2018
  • In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 97:5
  • Journal article (peer-reviewed)abstract
    • By analyzing a data sample of 2.93 fb(-1) collected at root s = 3.773 GeV with the BESIII detector operated at the BEPCII storage rings, we measure the branching fractions B(D-0 -> omega eta) = (2.15 +/- 0.17(stat) +/- 0.15(sys)) x 10(-3), B(D-0 ->eta pi(0)) = (0.58 +/- 0.05(stat) +/- 0.05(sys)) x 10(-3), B(D-0 ->eta'pi(0)) = (0.93 +/- 0.11(stat) +/- 0.09(sys)) x 10(-3), B(D-0 -> eta eta) = (2.20 +/- 0.07(stat) +/- 0.06(sys)) x 10(-3) and B(D-0 -> eta'eta) = (0.94 degrees +/- 0.25(stat) +/- 0.11(sys)) x 10(-3). We note that B(D-0 -> omega eta) is measured for the first time and that B(D-0 -> eta eta) is measured with much improved precision.
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23.
  • Ablikim, M., et al. (author)
  • Observation and Spin-Parity Determination of the X(1835) in J/psi -> gamma(KSKS0)-K-0 eta
  • 2015
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 115:9
  • Journal article (peer-reviewed)abstract
    • We report an observation of the process J/psi -> gamma X(1835) -> gamma(KSKS0)-K-0 eta at low (KSKS0)-K-0 mass with a statistical significance larger than 12.9s using a data sample of 1.31 x 109 J/psi events collected with the BESIII detector. In this region of phase space the (KSKS0)-K-0 system is dominantly produced through the f (0)(980). By performing a partial wave analysis, we determine the spin parity of the Xd1835_ to be J(PC) = 0(-+). The mass and width of the observed X(1835) are 1844 +/- 9(stat)(-25)(+16)(syst) MeV/c(2) and 192(-17)(+20)(sta)(-43)(+62)(syst) MeV, respectively, which are consistent with the results obtained by BESIII in the channel J/psi -> gamma pi(+)pi(-)eta'.
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24.
  • Ablikim, M., et al. (author)
  • Observation of a Neutral Charmoniumlike State Z(c)(4025)(0) in e(+)e(-) -> (D*(D)over-bar*)(0)pi(0)
  • 2015
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 115:18
  • Journal article (peer-reviewed)abstract
    • We report a study of the process e(+)e(-) -> (D*(D) over bar*)(0)pi(0) using e(+)e(-) collision data samples with integrated luminosities of 1092 pb(-1) at root s = 4.23 GeV and 826 pb(-1) at root s = 4.26 GeV collected with the BESIII detector at the BEPCII storage ring. We observe a new neutral structure near the (D*(D) over bar*)(0) mass threshold in the pi(0) recoil mass spectrum, which we denote as Z(c)(4025)(0). Assuming a Breit-Wigner line shape, its pole mass and pole width are determined to be (4025.5(-4.7)(+2.0) +/- 3.1) MeV/c(2) and (23.0 +/- 6.0 +/- 1.0) MeV, respectively. The Born cross sections of e(+)e(-) -> Z(c)(4025)(0)pi(0) -> (D*(D) over bar*)(0)pi(0) are measured to be (61.6 +/- 8.2 +/- 9.0) pb at root s = 4.23 GeV and (43.4 +/- 8.0 +/- 5.4) pb at root s = 4.26 GeV. The first uncertainties are statistical and the second are systematic.
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25.
  • Ablikim, M., et al. (author)
  • Observation of e(+)e(-) -> gamma X(3872) at BESIII
  • 2014
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 112:9, s. 092001-
  • Journal article (peer-reviewed)abstract
    • With data samples collected with the BESIII detector operating at the BEPCII storage ring at center-of-mass energies from 4.009 to 4.420 GeV, the process e(+)e(-) -> gamma X(3872) is observed for the first time with a statistical significance of 6.3 sigma. The measured mass of the X(3872) is (3871.9 +/- 0.7(stat) +/- 0.2(syst)) MeV/c(2), in agreement with previous measurements. Measurements of the product of the cross section sigma[e(+)e(-) -> gamma X(3872)] and the branching fraction B [X(3872) -> pi(+)pi(-)J/psi] at center-of-mass energies 4.009, 4.229, 4.260, and 4.360 GeV are reported. Our measurements are consistent with expectations for the radiative transition process Y(4260) -> gamma X(3872).
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26.
  • Ablikim, M., et al. (author)
  • Observation of e(+)e(-) -> phi chi(c1) and phi chi(c2) at root s=4.600 GeV
  • 2018
  • In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 97:3
  • Journal article (peer-reviewed)abstract
    • Using a data sample collected with the BESIII detector operating at the BEPCII storage ring at a center-of-mass energy of root s = 4.600 GeV, we search for the production of e(+)e(-) -> phi chi(c0,1,2). A search is also performed for the charmonium-like state X(4140) in the radiative transition e(+)e(-) -> gamma X(4140) with X(4140) subsequently decaying into phi J/psi The processes e(+)e(-) -> phi chi(c1) and phi chi(c2) are observed for the first time, each with a statistical significance of more than 10 sigma, and the Born cross sections are measured to be (4.2(-1.0)(+1.7) +/- 0.3) and (6.7(-1.7)(+3.4) +/- 0.5) pb, respectively, where the first uncertainties are statistical and the second systematic. No significant signals are observed for e(+)e(-) -> phi chi(c0) and e(+)e(-) -> gamma X(4140) and upper limits on the Born cross sections at 90% C. L. are provided at root s = 4.600 GeV.
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27.
  • Ablikim, M., et al. (author)
  • Observation of eta' -> pi(+) pi(-) pi(+) pi(-) and eta' -> pi(+) pi(-) pi(0) pi(0)
  • 2014
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 112:25, s. 251801-
  • Journal article (peer-reviewed)abstract
    • Using a sample of 1.3 x 10(9) J/psi events collected with the BESIII detector, we report the first observation of eta' -> pi(+) pi(-) pi(+) pi(-) and eta' -> pi(+) pi(-) pi(0) pi(0). The measured branching fractions are B(eta' -> pi(+) pi(-) pi(+) pi(-)) = [8.53 +/- 0.69(stat.) +/- 0.64(syst.)] x 10(-5) and B(eta' -> pi(+) pi(-) pi(0) pi(0)) = [1.82 +/- 0.35(stat.) +/- 0.18(syst.)] x 10(-4), which are consistent with theoretical predictions based on a combination of chiral perturbation theory and vector-meson dominance.
  •  
28.
  • Ablikim, M., et al. (author)
  • Observation of h(1)(1380) in the J/psi -> eta ' K(K)over-bar pi decay
  • 2018
  • In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 98:7
  • Journal article (peer-reviewed)abstract
    • Using 1.31 x 10(9) J/psi events collected by the BESIII detector at the BEPCII e(+)e(-) collider, we report the first observation of the h(1)(1380) in J/psi -> eta'h(1)(1380) with a significance of more than ten standard deviations. The mass and width of the possible axial-vector strangeonium candidate h(1)(1380) are measured to be M = (1423.2 +/- 2.1 +/- 7.3) MeV/c(2) and Gamma = (90.3 +/- 9.8 +/- 17.5) MeV. The product branching fractions, assuming no interference, are determined to be B(J/psi -> eta'h(1)(1380)) x B(h(1)(1380) -> K*(892)K-+(-)+c.c.) = (1.51 +/- 0.09 +/- 0.21) x 10(-4) in eta'K+K-pi(0) mode and B(J/psi -> eta'h(1)(1380)) x B(h(1)(1380) -> K*(892)(K) over bar +c.c.) =(2.16 +/- 0.12 +/- 0.29) x 10(-4) in eta'(KSK +/-)-K-0 pi(-/+) mode. The first uncertainties are statistical and the second are systematic. Isospin symmetry violation is observed in the decays h(1)(1380) K*(892)K-+(-) + c.c. and h(1)(1380) -> K*(892)(0)(K) over bar (0) + c.c.. Based on the measured h(1)(1380) mass, the mixing angle between the states h(1)(1170) and h(1)(1380) is determined to be (35.9 +/- 2.6)degrees, consistent with theoretical expectations.
  •  
29.
  • Ablikim, M., et al. (author)
  • Observation of J/psi -> p(p)over-bara(0)(980) at BESIII
  • 2014
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 90:5, s. 052009-
  • Journal article (peer-reviewed)abstract
    • Using 2.25 x 10(8) J/psi events collected with the BESIII detector at the BEPCII storage rings, we observe for the first time the process J/psi -> p (p) over bara(0)(980) -> pi(0)eta with a significance of 6.5 sigma (3.2 sigma including systematic uncertainties). The product branching fraction of J/psi -> p (p) over bara(0)(980) -> p (p) over bara(0)pi(0)eta is measured to be (6.8 +/- 1.2 +/- 1.3) x 10(-5), where the first error is statistical and the second is systematic. This measurement provides information on the a(0) production near threshold coupling to p (p) over bar and improves the understanding of the dynamics of J/psi decays to four-body processes.
  •  
30.
  • Ablikim, M., et al. (author)
  • Observation of Z(c)(3900)(0) in e(+)e(-) -> pi(0)pi(0) J/Psi
  • 2015
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 115:11
  • Journal article (peer-reviewed)abstract
    • Using a data sample collected with the BESIII detector operating at the BEPCII storage ring, we observe a new neutral state Z(c)(3900)(0) with a significance of 10.4 sigma. The mass and width are measured to be 3894.8 +/- 2.3 +/- 3.2 MeV/c(2) and 29.6 +/- 8.2 +/- 8.2 MeV, respectively, where the first error is statistical and the second systematic. The Born cross section for e(+)e(-) -> pi(0)pi(0) J/Psi and the fraction of it attributable to pi(0)Z(c)(3900)(0) -> pi(0)pi(0) J/Psi in the range E-c.m. = 4.19-4.42 GeV are also determined. We interpret this state as the neutral partner of the four-quark candidate Z(c)(3900)(+/-).
  •  
31.
  • Ablikim, M., et al. (author)
  • Observation of χc2→η′η′ and χc0,2→ηη′
  • 2017
  • In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:11
  • Journal article (peer-reviewed)abstract
    • Using a sample of 448.1×106  ψ(3686) events collected with the BESIII detector in 2009 and 2012, we study the decays χc0,2→η′η′ and ηη′. The decays χc2→η′η′, χc0→ηη′ and χc2→ηη′ are observed for the first time with statistical significances of 9.6σ, 13.4σ and 7.5σ, respectively. The branching fractions are determined to be B(χc0→η′η′)=(2.19±0.03±0.14)×10−3, B(χc2→η′η′)=(4.76±0.56±0.38)×10−5, B(χc0→ηη′)=(8.92±0.84±0.65)×10−5 and B(χc2→ηη′)=(2.27±0.43±0.25)×10−5, where the first uncertainties are statistical and the second are systematic. The precision for the measurement of B(χc0→η′η′) is significantly improved compared to previous measurements. Based on the measured branching fractions, the role played by the doubly and singly Okubo-Zweig-Iizuka disconnected transition amplitudes for χc0,2 decays into pseudoscalar meson pairs can be clarified.
  •  
32.
  • Ablikim, M., et al. (author)
  • Observation of ψ(3686)→n¯n and improved measurement of ψ(3686)→p¯p
  • 2018
  • In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 98:3
  • Journal article (peer-reviewed)abstract
    • We observe the decay psi (3686) -> n (n) over bar for the first time and measure psi (3686) -> p (p) over bar with improved accuracy by using 1.07 x 10(8) psi (3686) events collected with the BESIII detector. The measured branching fractions are B(psi(3686) -> n (n) over bar) = (3.06 +/- 0.06 +/- 0.14) x 10(-4) and B(psi(3686) -> p (p) over bar) = (3.05 +/- 0.02 +/- 0.12) x 10(-4). Here, the first uncertainties are statistical, and the second ones are systematic. With the hypothesis that the polar angular distributions of the neutron and proton in the center-of-mass system obey 1 + alpha cos(2) theta, we determine the a parameters to be alpha(n (n) over bar) = 0.68 +/- 0.12 +/- 0.11 and alpha(p (p) over bar) = 1.03 +/- 0.06 +/- 0.03 for psi(3686) -> n (n) over bar and psi(3686) -> p (p) over bar, respectively.
  •  
33.
  • Ablikim, M., et al. (author)
  • Precision measurement of the mass of the tau lepton
  • 2014
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 90:1
  • Journal article (peer-reviewed)abstract
    • An energy scan near the tau pair production threshold has been performed using the BESIII detector. About 24 pb(-1) of data, distributed over four scan points, were collected. This analysis is based on t pair decays to ee, e mu, eh, h, hh, e.,. and p. final states, where h denotes a charged p or K. The mass of the t lepton is measured from a maximum likelihood fit to the t pair production cross- section data to be m(tau) = 1776.91 +/- 0.12_0.10 - 0.13 _ MeV/c(2), which is currently the most precise value in a single measurement.
  •  
34.
  • Ablikim, M., et al. (author)
  • Search for h(c) -> pi(+)pi(-) J/psi via psi(3686) -> pi(0)pi(+)pi(-) J/psi
  • 2018
  • In: Physical Review D. - : American Physical Society. - 2470-0010 .- 2470-0029. ; 97:5
  • Journal article (peer-reviewed)abstract
    • Using a data sample of 448.1 x 10(6) psi(3686) events collected with the BESIII detector operating at the BEPCII, we perform search for the hadronic transition h(c)-> pi(+)pi(-) J/psi via psi (3686) -> pi(0)hc. No signals of the transition are observed, and the upper limit on the product branching fraction B(sigma(3686) -> pi(0)h(c))B(h(c) -> pi(+)pi(-) J/psi) at the 90% confidence level (C. L.) is determined to be 2.0 x 10(-6). This is the most stringent upper limit to date.
  •  
35.
  • Ablikim, M., et al. (author)
  • Search for the radiative transitions Psi(3770) -> gamma eta(c) and gamma eta(c) (2S)
  • 2014
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 89:11, s. 112005-
  • Journal article (peer-reviewed)abstract
    • By using a 2.92 fb-1 data sample taken at pffisffiffi 3.773 GeV with the BESIII detector operating at the BEPCII collider, we search for the radiative transitions.d3770c and cd2S through the hadronic decays cdcd2S. K0 SK p. No significant excess of signal events above background is observed. We set upper limits at a 90% confidence level for the product branching fractions to be Bdd3770cxBd.c. K0 SK k p < 1.6x10-5 and Bd.d3770cd2SxBd.cd2S. K0 SK p<5.6x10-6. Combining our result with world-average values of Bd.cd.cd2S. K0 SK p, we find the branching fractions Bd.d3770c< 6.8 x 10-4 and Bd.d3770cd2S< 2.0 x 10-3 at a 90% confidence level.
  •  
36.
  • Ablikim, M., et al. (author)
  • Search for the rare decay D+ → D0e+νe
  • 2017
  • In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:9
  • Journal article (peer-reviewed)abstract
    • Using a data set with an integrated luminosity of 2.93 fb(-1) collected at root s = 3.773 GeV with the BESIII detector operating at the BEPCII storage rings, we search for the rare decay D+ -> D(0)e(+)nu(e). No signal events are observed. We set the upper limit on the branching fraction for D+ -> D(0)e(+)nu(e) to be 1.0 x 10(-4) at the 90% confidence level.
  •  
37.
  • Ablikim, M., et al. (author)
  • Search for the rare decays J/y -> D-s(-) rho(+) and J/psi -> <(D)over bar(0)<(K)over bar*(0)
  • 2014
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 89:7, s. 071101-
  • Journal article (peer-reviewed)abstract
    • A search for the rare decays of J/psi -> D-S(-) rho(+) + c.c. and J/psi -> <(D)over bar(0)<(K)over bar*(0) + c.c. is performed with a data sample of 225.3-million J/psi events collected with the Beijing Spectrometer III detector. No evident signal is observed. Upper limits on the branching fractions are determined to be beta(J/psi -> D-S(-)rho(+) + c.c.) < 1.3 x 10(-5) and beta(J/psi -> <(D)over bar(0)<(K)over bar*(0) + c.c.) < 2.5 x 10(-6) at the 90% confidence level.
  •  
38.
  • Ablikim, M., et al. (author)
  • Search for the rare decays J/ψ→D0e+e−+c.c. and ψ(3686)→D0e+e−+c.c.
  • 2017
  • In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:11
  • Journal article (peer-reviewed)abstract
    • Using the data samples of (1310.6 +/- 7.2) x 10(6) J/psi events and (448.1 +/- 2.9) x 10(6) psi(3686) events collected with the BESIII detector, we search for the rare decays J/psi -> D(0)e(+) e(-) + c.c. and psi(3686) -> D(0)e(+) e(-) + c.c. No significant signals are observed and the corresponding upper limits on the branching fractions at the 90% confidence level are determined to be B(J/psi -> D(0)e(+) e(-) + c.c.) < 8.5 x 10(-8) and B(psi(3686) -> D(0)e(+) e(-) + c.c.) < 1.4 x 10(-7), respectively. Our limit on B(J/psi -> D(0)e(+) e(-) + c.c.) is more stringent by 2 orders of magnitude than the previous results, and B(psi(3686) -> D(0)e(+) e(-) + c.c.) is measured for the first time.
  •  
39.
  • Ablikim, M., et al. (author)
  • Search for Z(c)(3900)(+/-) -> omega pi(+/-)
  • 2015
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 92:3
  • Journal article (peer-reviewed)abstract
    • The decay Z(c)(3900)(+/-) -> omega pi(+/-) is searched for using data samples collected with the BESIII detector operating at the BEPCII storage ring at center-of-mass energies root s = 4.23 and 4.26 GeV. No significant signal for the Z(c)(3900)(+/-) is found, and upper limits at the 90% confidence level on the Born cross section for the process e(+)e(-) -> Z(c)(3900)(+/-) pi(-/+) -> omega pi(+)pi(-) are determined to be 0.26 and 0.18 pb at root s = 4.23 and 4.26 GeV, respectively.
  •  
40.
  • Ablikim, M., et al. (author)
  • Search for ψ(3686)→γηc(η(1405))→γπ+π−π0
  • 2017
  • In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:11
  • Journal article (peer-reviewed)abstract
    • Using a sample of 448.1×106  ψ(3686) events collected with the BESIII detector, a search for the isospin violating decay ηc→π+π−π0 via ψ(3686)→γηc is presented. No signal is observed, and the upper limit on B(ψ(3686)→γηc)×B(ηc→π+π−π0) is determined to be 1.6×10−6 at the 90% confidence level. In addition, a search for η(1405)→f0(980)π0 in ψ(3686) radiative decays is performed. No signal is observed, and the branching fraction B(ψ(3686)→γη(1405))×B(η(1405)→f0(980)π0)×B(f0(980)→π+π−) is calculated to be less than 5.0×10−7 at the 90% confidence level.
  •  
41.
  • Ablikim, M., et al. (author)
  • Study of e(+)e(-) -> p(p)over-bar in the vicinity of psi(3770)
  • 2014
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 735, s. 101-107
  • Journal article (peer-reviewed)abstract
    • Using 2917 pb(-1) of data accumulated at 3.773 GeV, 44.5 pb(-1) of data accumulated at 3.65 GeV and data accumulated during a psi(3770) line-shape scan with the BESIII detector, the reaction e(+)e(-) -> p (p) over bar is studied considering a possible interference between resonant and continuum amplitudes. The cross section of e(+)e(-) -> psi(3770) -> p (p) over bar, sigma(e(+)e(-)-> psi(3770) -> p (p) over bar), is found to have two solutions, determined to be (0.059(-0.020)(+0.070) +/- 0.012) pb with the phase angle phi = (255.8(-26.6)(+39.0) +/- 4.8). (< 0.166 pb at the 90% confidence level), or sigma(e(+)e(-) -> psi(3770) -> p<(p)over bar>) = (2.57(-0.13)(+0.12) +/- 0.12) pb with phi = (266.9(-6.3)(+6.1) +/- 0.9)degrees both of which agree with a destructive interference. Using the obtained cross section of psi(3770) -> p (p) over bar, the cross section of p (p) over bar -> psi(3770), which is useful information for the future PANDA experiment, is estimated to be either (9.8(-3.9)(+11.8)) nb (< 27.5 nb at 90% C.L.) or (425.6(-43.7)(+42.9)) nb. (C) 2014 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license.
  •  
42.
  • Ablikim, M., et al. (author)
  • Study of e(+)e(-) -> p(p)over-bar pi(0) in the vicinity of the psi(3770)
  • 2014
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 90:3, s. 032007-
  • Journal article (peer-reviewed)abstract
    • The process e(+)e(-) -> p (p) over bar pi(0) has been studied by analyzing data collected at root s = 3.773 GeV, root s = 3.650 GeV, and during a psi(3770) line shape scan with the BESIII detector at the BEPCII collider. The Born cross section of p (p) over bar pi(0) in the vicinity of the psi(3770) is measured, and the Born cross section of psi(3770) -> p (p) over bar pi(0) is extracted considering interference between resonant and continuum production amplitudes. Two solutions with the same probability and a significance of 1.5 sigma are found. The solutions for the Born cross section of psi(3770) -> p (p) over bar pi(0) are 33.8 +/- 1.8 +/- 2.1 pb and 0.06(-0.04-0.01)(+0.10+0.01) pb (< 0.22 pb at a 90% confidence level). Using the estimated cross section and a constant decay amplitude approximation, the cross section sigma(p<(p)over bar> -> psi(3770)pi(0)) is calculated for the kinematic situation of the planned (p) over bar ANDA experiment. The maximum cross section corresponding to the two solutions is expected to be less than 0.79 nb at 90% confidence level and 122 +/- 10 nb at a center-of-mass energy of 5.26 GeV.
  •  
43.
  • Ablikim, M., et al. (author)
  • Study of J/ψ and ψ(3686) decays to π+π−η′
  • 2017
  • In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:11
  • Journal article (peer-reviewed)abstract
    • Using the data samples of 1.31×109  J/ψ events and 4.48×108  ψ(3686) events collected with the BESIII detector, partial wave analyses on the decays J/ψ and ψ(3686)→π+π−η′ are performed with a relativistic covariant tensor amplitude approach. The dominant contribution is found to be J/ψ and ψ(3686) decays to ρη′. In the J/ψ decay, the branching fraction B(J/ψ→ρη′) is determined to be (7.90±0.19(stat)±0.49(sys))×10−5. Two solutions are found in the ψ(3686) decay, and the corresponding branching fraction B(ψ(3686)→ρη′) is (1.02±0.11(stat)±0.24(sys))×10−5 for the case of destructive interference, and (5.69±1.28(stat)±2.36(sys))×10−6 for constructive interference. As a consequence, the ratios of branching fractions between ψ(3686) and J/ψ decays to ρη′ are calculated to be (12.9±1.4(stat)±3.1(sys))% and (7.2±1.6(stat)±3.0(sys))%, respectively. We also determine the inclusive branching fractions of J/ψ and ψ(3686) decays to π+π−η′ to be (1.36±0.02(stat)±0.08(sys))×10−4 and (1.51±0.14(stat)±0.23(sys))×10−5, respectively
  •  
44.
  • Ablikim, M., et al. (author)
  • Study of the decays D+-> eta(('))e(+)nu(e)
  • 2018
  • In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 97:9
  • Journal article (peer-reviewed)abstract
    • The charm semileptonic decays D+ -> eta e(+)nu(e) and D+ -> eta'e(+)nu(e) are studied with a sample of e(+)e(-) collision data corresponding to an integrated luminosity of 2.93 fb(-1) collected at root s = 3.773 GeV with the BESIII detector. We measure the branching fractions for D+ -> eta e(+)upsilon(e) to be (10.74 +/- 0.81 +/- 0.51)x10(-4), and for D+ -> eta'e(+)nu(e) to be (1.91 +/- 0.51 +/- 0.13) x 10(-4), where the uncertainties are statistical and systematic, respectively. In addition, we perform a measurement of the form factor in the decay D+ -> eta e(+)nu(e) . All the results are consistent with those obtained by the CLEO-c experiment.
  •  
45.
  • Ablikim, M., et al. (author)
  • Study of two-photon decays of pseudoscalar mesons via J/Psi radiative decays
  • 2018
  • In: Physical Review D. - 2470-0010 .- 2470-0029. ; 97:7
  • Journal article (peer-reviewed)abstract
    • Using a sample of 4.48 x 10(8) Psi(3686) events collected with the BESIII detector at the BEPCII collider, we study the two-photon decays of the pseudoscalar mesons pi(0,) eta , eta' , eta(1405), eta(1475), eta(1760), and X(1835) in J/Psi radiative decays using Psi(3686) -> pi(+) pi(-) J/Psi events. The pi(0), eta, and eta' mesons are clearly observed in the two-photon mass spectra, and the branching fractions are determined to be B(J/Psi -> gamma pi(0) -> 3 gamma) = (3.57 +/- 0.12 +/- 0.16) x 10(-5), B(J/Psi -> gamma eta -> 3 gamma) = (4.42 +/- 0.04 +/- 0.18) x 10(-4), and B(J/Psi -> gamma eta' -> 2 gamma) = (1.26 +/- 0.02 +/- 0.05) x 10(-4), where the first error is statistical and the second is systematic. No clear signal for eta(1405), eta(1475), eta(1760) or X(1835) is observed in the two- photon mass spectra, and upper limits at the 90% confidence level on the product branching fractions are obtained.
  •  
46.
  • Sampson, Joshua N., et al. (author)
  • Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for 13 Cancer Types
  • 2015
  • In: Journal of the National Cancer Institute. - : Oxford University Press (OUP). - 0027-8874 .- 1460-2105. ; 107:12
  • Journal article (peer-reviewed)abstract
    • Background: Studies of related individuals have consistently demonstrated notable familial aggregation of cancer. We aim to estimate the heritability and genetic correlation attributable to the additive effects of common single-nucleotide polymorphisms (SNPs) for cancer at 13 anatomical sites. Methods: Between 2007 and 2014, the US National Cancer Institute has generated data from genome-wide association studies (GWAS) for 49 492 cancer case patients and 34 131 control patients. We apply novel mixed model methodology (GCTA) to this GWAS data to estimate the heritability of individual cancers, as well as the proportion of heritability attributable to cigarette smoking in smoking-related cancers, and the genetic correlation between pairs of cancers. Results: GWAS heritability was statistically significant at nearly all sites, with the estimates of array-based heritability, h(l)(2), on the liability threshold (LT) scale ranging from 0.05 to 0.38. Estimating the combined heritability of multiple smoking characteristics, we calculate that at least 24% (95% confidence interval [CI] = 14% to 37%) and 7% (95% CI = 4% to 11%) of the heritability for lung and bladder cancer, respectively, can be attributed to genetic determinants of smoking. Most pairs of cancers studied did not show evidence of strong genetic correlation. We found only four pairs of cancers with marginally statistically significant correlations, specifically kidney and testes (rho = 0.73, SE = 0.28), diffuse large B-cell lymphoma (DLBCL) and pediatric osteosarcoma (rho = 0.53, SE = 0.21), DLBCL and chronic lymphocytic leukemia (CLL) (rho = 0.51, SE = 0.18), and bladder and lung (rho = 0.35, SE = 0.14). Correlation analysis also indicates that the genetic architecture of lung cancer differs between a smoking population of European ancestry and a nonsmoking Asian population, allowing for the possibility that the genetic etiology for the same disease can vary by population and environmental exposures. Conclusion: Our results provide important insights into the genetic architecture of cancers and suggest new avenues for investigation.
  •  
47.
  • Ablikim, M., et al. (author)
  • Amplitude analysis of D0 → K -π+π+π-
  • 2017
  • In: Physical Review D. - 2470-0010 .- 2470-0029. ; 95:7
  • Journal article (peer-reviewed)abstract
    • We present an amplitude analysis of the decay D0 → K -π+π+π- based on a data sample of 2.93  fb−1 acquired by the BESIII detector at the ψ(3770) resonance. With a nearly background free sample of about 16000 events, we investigate the substructure of the decay and determine the relative fractions and the phases among the different intermediate processes. Our amplitude model includes the two-body decays D0 → ¯K*0ρ0, D0 → K−a+1(1260) and D0 → K−1(1270)π+, the three-body decays D0 →¯K*0π+π− and D0 → K−π+ρ0, as well as the four-body nonresonant decay D0 → K−π+π+π−. The dominant intermediate process is D0 → K−a+1(1260), accounting for a fit fraction of 54.6%.
  •  
48.
  • Ablikim, M., et al. (author)
  • Amplitude analysis of the chi(c1) -> eta pi(+)pi(-) decays
  • 2017
  • In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 95:3
  • Journal article (peer-reviewed)abstract
    • Using 448.0 x 10(6) psi(3686) events collected with the BESIII detector, an amplitude analysis is performed for psi(3686) -> gamma chi(c1), chi(c1) ->eta pi(+)pi(-) decays. The most dominant two- body structure observed is a(0)(980)(+/-) pi(-/+); a(0)(980)(+/-) -> eta pi(+/-.) line shape is modeled using a dispersion relation, and a significant nonzero a(0) (980) coupling to the eta'pi channel is measured. We observe chi(c1) -> a(2)(1700)pi production for the first time, with a significance larger than 17 sigma. The production of mesons with exotic quantum numbers, J(PC) = 1(-+), is investigated, and upper limits for the branching fractions chi(c1) -> pi(1)(1400)(+/-)pi(-/+) , chi(c1) -> pi(1)(1600)(+/-)pi(-/+) and chi(c1) -> pi 1(2015)(+/-)pi(-/+) with subsequent pi(1)(X)(+/-) -> eta pi(+/-) decay, are determined.
  •  
49.
  • Ablikim, M., et al. (author)
  • Amplitude Analysis of the Decays eta ' -> pi(+)pi(-)pi(0) and eta' -> pi(0)pi(0)pi(0)
  • 2017
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 118:1
  • Journal article (peer-reviewed)abstract
    • Based on a sample of 1.31 x 10(9) J/Psi events collected with the BESIII detector, an amplitude analysis of the isospin-violating decays eta' -> pi(+)pi(-)pi(0) and eta' -> pi(0)pi(0)pi(0) is performed. A significant P-wave contribution from eta' -> rho(+/-)eta(-/+) is observed for the first time in eta' -> pi(+)pi(-)pi(0). The branching fraction is determined to be B(eta' -> rho(+/-)pi(-/+)) = (7.44 +/- 0.60 +/- 1.26 +/- 1.84) x 10(-4), where the first uncertainty is statistical, the second systematic, and the third model dependent. In addition to the nonresonant S-wave component, there is a significant sigma meson component. The branching fractions of the combined S-wave components are determined to be B(eta' -> pi(+)pi(-)pi(0))(S) = (37.63 +/- 0.77 +/- 2.22 +/- 4.48) x 10(-4) and B(eta' -> pi(0)pi(0)pi(0)) = (35.22 +/- 0.82 +/- 2.54) x 10(-4), respectively. The latter one is consistent with previous BESIII measurements.
  •  
50.
  • Ablikim, M., et al. (author)
  • Amplitude analysis of the π$^0$π$^0$ system produced in radiative J/ψ decays
  • 2016
  • In: PHYSICAL REVIEW D. - 2470-0010. ; 93:3
  • Journal article (peer-reviewed)abstract
    • An amplitude analysis of the π0π0 system produced in radiative J/ψ decays is presented. In particular, a piecewise function that describes the dynamics of the π0π0 system is determined as a function of Mπ0π0 from an analysis of the (1.311±0.011)×109 J/ψ decays collected by the BESIII detector. The goal of this analysis is to provide a description of the scalar and tensor components of the π0π0 system while making minimal assumptions about the properties or number of poles in the amplitude. Such a model-independent description allows one to integrate these results with other related results from complementary reactions in the development of phenomenological models, which can then be used to directly fit experimental data to obtain parameters of interest. The branching fraction of J/ψ→γπ0π0 is determined to be (1.15±0.05)×10-3, where the uncertainty is systematic only and the statistical uncertainty is negligible.
  •  
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