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Search: WFRF:(Khalaf H)

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1.
  • Bravo, L, et al. (author)
  • 2021
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  • Tabiri, S, et al. (author)
  • 2021
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  • 2019
  • Journal article (peer-reviewed)
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  • Duffy, J. M. N., et al. (author)
  • Developing a core outcome set for future infertility research: an international consensus development study
  • 2020
  • In: Human Reproduction. - : Oxford University Press (OUP). - 0268-1161 .- 1460-2350. ; 35:12, s. 2725-2734
  • Journal article (peer-reviewed)abstract
    • STUDY QUESTION: Can a core outcome set to standardize outcome selection, collection and reporting across future infertility research be developed? SUMMARY ANSWER: A minimum data set, known as a core outcome set, has been developed for randomized controlled trials (RCTs) and systematic reviews evaluating potential treatments for infertility. WHAT IS KNOWN ALREADY: Complex issues, including a failure to consider the perspectives of people with fertility problems when selecting outcomes, variations in outcome definitions and the selective reporting of outcomes on the basis of statistical analysis, make the results of infertility research difficult to interpret. STUDY DESIGN, SIZE, DURATION: A three-round Delphi survey (372 participants from 41 countries) and consensus development workshop (30 participants from 27 countries). PARTICIPANTS/MATERIALS, SETTING, METHODS: Healthcare professionals, researchers and people with fertility problems were brought together in an open and transparent process using formal consensus science methods. MAIN RESULTS AND THE ROLE OF CHANCE: The core outcome set consists of: viable intrauterine pregnancy confirmed by ultrasound (accounting for singleton, twin and higher multiple pregnancy); pregnancy loss (accounting for ectopic pregnancy, miscarriage, stillbirth and termination of pregnancy); live birth; gestational age at delivery; birthweight; neonatal mortality; and major congenital anomaly. Time to pregnancy leading to live birth should be reported when applicable. LIMITATIONS, REASONS FOR CAUTION: We used consensus development methods which have inherent limitations, including the representativeness of the participant sample, Delphi survey attrition and an arbitrary consensus threshold. WIDER IMPLICATIONS OF THE FINDINGS: Embedding the core outcome set within RCTs and systematic reviews should ensure the comprehensive selection, collection and reporting of core outcomes. Research funding bodies, the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) statement, and over 80 specialty journals, including the Cochrane Gynaecology and Fertility Group, Fertility and Sterility and Human Reproduction, have committed to implementing this core outcome set.
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  • Duffy, J. M. N., et al. (author)
  • Top 10 priorities for future infertility research: an international consensus development study
  • 2020
  • In: Human Reproduction. - : Oxford University Press (OUP). - 0268-1161 .- 1460-2350. ; 35:12, s. 2715-2724
  • Journal article (peer-reviewed)abstract
    • STUDY QUESTION: Can the priorities for future research in infertility be identified? SUMMARY ANSWER: The top 10 research priorities for the four areas of male infertility, female and unexplained infertility, medically assisted reproduction and ethics, access and organization of care for people with fertility problems were identified. WHAT IS KNOWN ALREADY: Many fundamental questions regarding the prevention, management and consequences of infertility remain unanswered. This is a barrier to improving the care received by those people with fertility problems. STUDY DESIGN, SIZE, DURATION: Potential research questions were collated from an initial international survey, a systematic review of clinical practice guidelines and Cochrane systematic reviews. A rationalized list of confirmed research uncertainties was prioritized in an interim international survey. Prioritized research uncertainties were discussed during a consensus development meeting. Using a formal consensus development method, the modified nominal group technique, diverse stakeholders identified the top 10 research priorities for each of the categories male infertility, female and unexplained infertility, medically assisted reproduction and ethics, access and organization of care. PARTICIPANTS/MATERIALS, SETTING, METHODS: Healthcare professionals, people with fertility problems and others (healthcare funders, healthcare providers, healthcare regulators, research funding bodies and researchers) were brought together in an open and transparent process using formal consensus methods advocated by the James Lind Alliance. MAIN RESULTS AND THE ROLE OF CHANCE: The initial survey was completed by 388 participants from 40 countries, and 423 potential research questions were submitted. Fourteen clinical practice guidelines and 162 Cochrane systematic reviews identified a further 236 potential research questions. A rationalized list of 231 confirmed research uncertainties was entered into an interim prioritization survey completed by 317 respondents from 43 countries. The top 10 research priorities for each of the four categories male infertility, female and unexplained infertility (including age-related infertility, ovarian cysts, uterine cavity abnormalities and tubal factor infertility), medically assisted reproduction (including ovarian stimulation, IUI and IVF) and ethics, access and organization of care were identified during a consensus development meeting involving 41 participants from I I countries. These research priorities were diverse and seek answers to questions regarding prevention, treatment and the longer-term impact of infertility. They highlight the importance of pursuing research which has often been overlooked, including addressing the emotional and psychological impact of infertility, improving access to fertility treatment, particularly in lower resource settings and securing appropriate regulation. Addressing these priorities will require diverse research methodologies, including laboratory-based science, qualitative and quantitative research and population science. LIMITATIONS, REASONS FOR CAUTION: We used consensus development methods, which have inherent limitations, including the representativeness of the participant sample, methodological decisions informed by professional judgment and arbitrary consensus definitions. WIDER IMPLICATIONS OF THE FINDINGS: We anticipate that identified research priorities, developed to specifically highlight the most pressing clinical needs as perceived by healthcare professionals, people with fertility problems and others, will help research funding organizations and researchers to develop their future research agenda.
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11.
  • Duffy, J. M. N., et al. (author)
  • Standardizing definitions and reporting guidelines for the infertility core outcome set: an international consensus development study
  • 2020
  • In: Human Reproduction. - : Oxford University Press (OUP). - 0268-1161 .- 1460-2350. ; 35:12, s. 2735-2745
  • Journal article (peer-reviewed)abstract
    • STUDY QUESTION: Can consensus definitions for the core outcome set for infertility be identified in order to recommend a standardized approach to reporting? SUMMARY ANSWER: Consensus definitions for individual core outcomes, contextual statements and a standardized reporting table have been developed. WHAT IS KNOWN ALREADY: Different definitions exist for individual core outcomes for infertility. This variation increases the opportunities for researchers to engage with selective outcome reporting, which undermines secondary research and compromises clinical practice guideline development. STUDY DESIGN, SIZE, DURATION: Potential definitions were identified by a systematic review of definition development initiatives and clinical practice guidelines and by reviewing Cochrane Gynaecology and Fertility Group guidelines. These definitions were discussed in a face-to-face consensus development meeting, which agreed consensus definitions. A standardized approach to reporting was also developed as part of the process. PARTICIPANTS/MATERIALS, SETTING, METHODS: Healthcare professionals, researchers and people with fertility problems were brought together in an open and transparent process using formal consensus development methods. MAIN RESULTS AND THE ROLE OF CHANCE: Forty-four potential definitions were inventoried across four definition development initiatives, including the Harbin Consensus Conference Workshop Group and International Committee for Monitoring Assisted Reproductive Technologies, 12 clinical practice guidelines and Cochrane Gynaecology and Fertility Group guidelines. Twenty-seven participants, from 11 countries, contributed to the consensus development meeting. Consensus definitions were successfully developed for all core outcomes. Specific recommendations were made to improve reporting. LIMITATIONS, REASONS FOR CAUTION: We used consensus development methods, which have inherent limitations. There was limited representation from low- and middle-income countries. WIDER IMPLICATIONS OF THE FINDINGS: A minimum data set should assist researchers in populating protocols, case report forms and other data collection tools. The generic reporting table should provide clear guidance to researchers and improve the reporting of their results within journal publications and conference presentations. Research funding bodies, the Standard Protocol Items: Recommendations for Interventional Trials statement, and over 80 specialty journals have committed to implementing this core outcome set.
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14.
  • Lemoine, J E, et al. (author)
  • Factor structure and psychometric properties of the Body Appreciation Scale-2 among adolescents and young adults in Danish, Portuguese, and Swedish
  • 2018
  • In: Body image. - 1740-1445 .- 1873-6807. ; 26, s. 1-9
  • Journal article (peer-reviewed)abstract
    • In recent years, the study of body image shifted from focusing on the negative aspects to a more extensive view of body image. The present study seeks to validate a measure of positive body image, the Body Appreciation Scale-2 (BAS-2; Tylka & Wood-Barcalow, 2015a) in Denmark, Portugal, and Sweden. Participants (N = 1012) were adolescents and young adults aged from 12 to 19. Confirmatory factor analyses confirmed the one-dimensional factor structure of the scale. Multi-group confirmatory factor analyses indicated that the scale was invariant across sex and country. Further results showed that BAS-2 was positively correlated with self-esteem, psychological well-being, and intuitive eating. It was negatively correlated with BMI among boys and girls in Portugal but not in Denmark and Sweden. Additionally, boys had higher body appreciation than girls. Results indicated that the BAS-2 has good psychometric properties in the three languages.
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15.
  • Al Hashmi, I., et al. (author)
  • Translation and psychometric validation of the Arabic version of Summary of the Diabetes Self-Care Activities (SDSCA) among pregnant women with gestational diabetes
  • 2022
  • In: BMC Pregnancy and Childbirth. - : BioMed Central Ltd.. - 1471-2393. ; 22:1, s. 1-9
  • Journal article (peer-reviewed)abstract
    • Background and purpose: There is a lack of validated tools to assess adherence to gestational diabetes (GDM) management plan among women with GDM. This study aimed to translate the Summary of Diabetes Self-Care Activity (SDSCA) into Arabic, culturally adapt it, and test its psychometric properties among women with GDM.  Methods: A multiphase study was used to translate and evaluate the psychometric properties of the Arabic version of SDSCA using the following steps: (1) cultural and linguistic validation; (2) content and face validity testing; (3) construct validity testing; and (4) internal validity testing. Nineghty pregnant women with GDM were recruited to meet the purpose of this study.  Results: The Arabic version of the adapted SDSCA tool revealed adequate content validity, satisfactory internal consistency (Cronbach’s alpha = 0.74), and test-retest reliability (Pearson correlation coefficient =.67). Exploratory factor analysis revealed three factors that fit data satisfactory: diet, exercise, and blood glucose monitoring.  Conclusions: This study showed that the adapted Arabic SDSCA tool is an easy, valid, and reliable tool to assess pregnant women’s adherence to GDM management plan.
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  • El-Sayed, Ashraf S.A., et al. (author)
  • Production, bioprocess optimization and anticancer activity of Camptothecin from Aspergillus terreus and Aspergillus flavus, endophytes of Ficus elastica
  • 2021
  • In: Process Biochemistry. - : Elsevier. - 1359-5113 .- 1873-3298. ; 107, s. 59-73
  • Journal article (peer-reviewed)abstract
    • Attenuating the biosynthetic potency of camptothecin producing fungi with the multiple subculturing and storage is the major challenge that limits the scaling-up of this approach. Thus, screening for novel fungal isolates with reliable metabolic stability and sustainability for camptothecin production is the objective of this work. Among the recovered isolates, Aspergillus terreus (320 μg/l) and A. flavus (290 μg/l) "endophytes of Ficus elastica" were the most potent camptothecin producing isolates. The chemical identity of extracted camptothecin was resolved from the HPLC, NMR, FTIR and LC–MS analyses, with a strong antiproliferative activity against MCF7 (0.18 μM), LS174 T, HCT29 (0.29−0.43 μM), HEPG-2 (0.73 μM) cell lines. The yield of camptothecin was decreased by about > 60 % by the 7th subculturing for both fungal isolates. Upon using Blackett-Burman design to optimize their nutritional requirements by the fungal isolates, their yield of camptothecin were increased by approximately 2 folds, revealing the essentiality of some carbon, nitrogen and growth elicitors for biosynthesis of camptothecin. Interestingly, the biosynthetic machinery of camptothecin by the 7th generation fungal isolates were completely restored upon addition of 1% surface sterilized leaves of F. elastica, while all the other experimented plant extracts did not display any effect on camptothecin production. So, chemicals signals derived from the plant /or its entire microbiome "microbial communication" triggering the expression of camptothecin biosynthetic gene cluster of these fungi, could be the most conceivable hypothesis explaining the attenuation and restoration processes of camptothecin biosynthesis by target the fungal isolates. This is the first report describing the feasibility of A. terreus and A. flavus "endophytes of F. elastica" for camptothecin production with reliable metabolic and sustainable biosynthetic potency upon addition of the plant host's entire microbiome, that could be a preliminary platform for scaling-up of camptothecin production.
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  • Khalaf, Atika, et al. (author)
  • Determinants of physical activity (PA), sedentary behaviors, and BMI among female university students in South Western Saudia Arabia (KSA)
  • 2012
  • In: Clinical Nutrition Supplements, 2012, 7(1), page 263. ; , s. 263-
  • Conference paper (peer-reviewed)abstract
    • Rationale: The aim of this study was to examine the prevalence and determinants of PA, sedentary behaviors, and BMI among female university students in south western KSA.Methods: This cross-sectional study included 663 female students who were randomly selected from a female university centre. Logistic regressions were used to identify determinants for moderate and vigorous PA, sedentary behaviors, and overweight/obesity and underweight.Results: The females reported moderate PA in 49% and vigorous PA in 21% of cases, as defined by the American College of Sports Medicine recommendations. Total energy expenditure in METs-min/week increased with increased BMI (1216 among underweight, 1474 among normal weight, and 1810 among overweight). Sedentary behaviors were found among 15% of participants. The prevalence of overweight and obesity was 24%, and underweight 19%. Significant predictors for moderate PA were found to be present of one obese parent (negative relation), proximity to parks, and BMI (positive relation) while vigorous PA was predicted by age, fathers' level of education, waist-height ratio (negative relation), mothers' level of education, proximity to molls and parks, and BMI (positive relation). Sedentary behaviours were only predicted by proximity to parks. Overweight and obesity were found to correlate to the number of sisters (negative relation), presence of one obese parent, obese siblings, and proximity to molls (positive relation). On the other hand, both age and presence of obese parents were found to be negatively and significantly correlated to underweight.Conclusion: A minority of the subjects met with current recommendations for PA. Intervention studies and implementation of national nutritional and PA guidelines are needed and should be integrated in the education of the adolescents and young adults.
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  • Khalaf, Atika, et al. (author)
  • Determinants of physical activity (PA), sedentary behaviors, and BMI among female university students in South Western Saudia Arabia (KSA)
  • 2012
  • Conference paper (other academic/artistic)abstract
    • Rationale: The aim of this study was to examine the prevalence and determinants of PA, sedentary behaviors, and BMI among female university students in south western KSA. Methods: This cross-sectional study included 663 female students who were randomly selected from a female university centre. Logistic regressions were used to identify determinants for moderate and vigorous PA, sedentary behaviors, and overweight/obesity and underweight. Results: The females reported moderate PA in 49% and vigorous PA in 21% of cases, as defined by the American College of Sports Medicine recommendations. Total energy expenditure in METs-min/week increased with increased BMI (1216 among underweight, 1474 among normal weight, and 1810 among overweight). Sedentary behaviors were found among 15% of participants. The prevalence of overweight and obesity was 24%, and underweight 19%. Significant predictors for moderate PA were found to be present of one obese parent (negative relation), proximity to parks, and BMI (positive relation) while vigorous PA was predicted by age, fathers' level of education, waist-height ratio (negative relation), mothers' level of education, proximity to molls and parks, and BMI (positive relation). Sedentary behaviours were only predicted by proximity to parks. Overweight and obesity were found to correlate to the number of sisters (negative relation), presence of one obese parent, obese siblings, and proximity to molls (positive relation). On the other hand, both age and presence of obese parents were found to be negatively and significantly correlated to underweight. Conclusion: A minority of the subjects met with current recommendations for PA. Intervention studies and implementation of national nutritional and PA guidelines are needed and should be integrated in the education of the adolescents and young adults.
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24.
  • Khalaf, Atika, 1973-, et al. (author)
  • Discrepancies between actual, perceived and ideal body image among young female university students in southwestern Saudi Arabia
  • 2014
  • Conference paper (other academic/artistic)abstract
    • Rationale: Body-shape preference is an important determinant of obesity and underweight, but studies on body image among females in the Arab region are, at most, scanty. The aim of this study was to describe the prevalence of underweight and overweight/obesity among Saudi Arabian female university students, and to investigate discrepancies between their actual, perceived and ideal body shape.Methods: This cross sectional study included 663  female students in a university centre in Saudi Arabia. Anthropometric measurements including weight, height, BMI and body image scale (9-figures silhouette) were used. A cross-tabulation was made between “warped self-image” against “subjective goal image”. Regression analysis was used to predict variables related to body image perception.Results: The participants had a mean age of 20.4 years (SD 1.5), 16% were underweight and 25% were over- weight/obese.Discrepancy in subjective goal image: 44% wished they were slimmer and 20% that they were heavier than what they perceived themselves. Thus, 36% were happy with their current body shape.Warped self-image: It was 16% that thought they were slimmer and 18% that they were heavier than what they actually were. Thus, in 61% of cases the perceived body image was in agreement with their actual body shape. Cross-tabulation showed that only 23% had an agreemen tbetween their actual, perceived and ideal body shape. Of all variables entered into the regression analysis, only BMI was able to predict how the subject perceives herself in the body image scale (R square = 0.676; p < 0.000). None of the variables entered was significant enough to predict how the subject wishes to look like.Conclusion: Discrepancies between actual, perceived and ideal body image is common among the Saudi Arabian female students and can possibly lead to eating disorders and increased  prevalence of underweight oroverweight/obesity.
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25.
  • Khalaf, Atika, et al. (author)
  • Discrepancies between actual, perceived and ideal body image among young female university students in southwestern Saudi Arabia
  • 2014
  • Conference paper (other academic/artistic)abstract
    • Rationale: Body-shape preference is an important determinant of obesity and underweight, but studies on body image among females in the Arab region are, at most, scanty. The aim of this study was to describe the prevalence of underweight and overweight/obesity among Saudi Arabian female university students, and to investigate discrepancies between their actual, perceived and ideal body shape. Methods: This cross sectional study included 663  female students in a university centre in Saudi Arabia. Anthropometric measurements including weight, height, BMI and body image scale (9-figures silhouette) were used. A cross-tabulation was made between “warped self-image” against “subjective goal image”. Regression analysis was used to predict variables related to body image perception. Results: The participants had a mean age of 20.4 years (SD 1.5), 16% were underweight and 25% were over- weight/obese.Discrepancy in subjective goal image: 44% wished they were slimmer and 20% that they were heavier than what they perceived themselves. Thus, 36% were happy with their current body shape.Warped self-image: It was 16% that thought they were slimmer and 18% that they were heavier than what they actually were. Thus, in 61% of cases the perceived body image was in agreement with their actual body shape. Cross-tabulation showed that only 23% had an agreemen tbetween their actual, perceived and ideal body shape. Of all variables entered into the regression analysis, only BMI was able to predict how the subject perceives herself in the body image scale (R square = 0.676; p < 0.000). None of the variables entered was significant enough to predict how the subject wishes to look like. Conclusion: Discrepancies between actual, perceived and ideal body image is common among the Saudi Arabian female students and can possibly lead to eating disorders and increased  prevalence of underweight oroverweight/obesity.
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26.
  • Khalaf, Atika, 1973-, et al. (author)
  • Perceived and ideal body image in young women in South Western Saudi Arabia
  • 2015
  • In: Journal of Obesity. - : Hindawi Limited. - 2090-0708. ; 2015, s. 1-7
  • Journal article (peer-reviewed)abstract
    • Objectives. The aim of this study was to investigate perceived and ideal body image (BI) and associated factors among female university students in Saudi Arabia. Methods. This cross-sectional study included 663 university female students. Anthropometric measurements including weight, height, BMI, and BI perception (the 9-figure silhouette) were obtained. Descriptive and logistic regression analysis were conducted. Results. An agreement between actual, perceived, and ideal BI was found in 23% of the participants. Behavioral (activity levels), social (presence of obese parents and fathers’ level of education), and economic factors (households’ monthly income, number of cars in the household, and kind of residence) were positively and significantly associated with the desire to be thinner. Similarly, socioeconomic associations (number of sisters and number of cars in the household) correlated positively and significantly with the desire to be heavier. Conclusions. The whole family should rather be considered in interventions related to appearance concerns and BI discrepancies. Furthermore, campaigns targeting improvement of adolescents’ physical self-image should be a major priority of the public health sector.
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27.
  • Khalaf, Atika, et al. (author)
  • Perceived and ideal body image in young women in South Western Saudi Arabia
  • 2015
  • In: Journal of Obesity. - : Hindawi Limited. - 2090-0708 .- 2090-0716. ; 2015, s. 1-7
  • Journal article (peer-reviewed)abstract
    • Objectives. The aim of this study was to investigate perceived and ideal body image (BI) and associated factors among female university students in Saudi Arabia. Methods. This cross-sectional study included 663 university female students. Anthropometric measurements including weight, height, BMI, and BI perception (the 9-figure silhouette) were obtained. Descriptive and logistic regression analysis were conducted. Results. An agreement between actual, perceived, and ideal BI was found in 23% of the participants. Behavioral (activity levels), social (presence of obese parents and fathers’ level of education), and economic factors (households’ monthly income, number of cars in the household, and kind of residence) were positively and significantly associated with the desire to be thinner. Similarly, socioeconomic associations (number of sisters and number of cars in the household) correlated positively and significantly with the desire to be heavier. Conclusions. The whole family should rather be considered in interventions related to appearance concerns and BI discrepancies. Furthermore, campaigns targeting improvement of adolescents’ physical self-image should be a major priority of the public health sector.
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28.
  • Khalaf, Atika, et al. (author)
  • Prevalence and determinants of obesity and physical inactivity among female university students in South Western Saudi Arabia
  • 2011
  • In: Clinical Nutrition Supplements. ; , s. 100-
  • Conference paper (peer-reviewed)abstract
    • Rationale: The prevalence of obesity in Saudi Arabia (KSA) is a growing challenge to public health, it may affect and be related to the levels of physical activity. The aim of this study was to examine the prevalence of overweight and obesity, physical activity, and unhealthy food intake among female university students in Saudi Arabia. In addition, determinants for levels of physical activity and unhealthy food intake were examined.Methods: This cross-sectional study included 663 female students in a university centre in KSA. Measures included anthropometric, socioeconomic, environmental, cultural, and life style factors such as physical activities, sedentary activities and eating habits. Logistic regressions were used to identify predictors of physical activity and unhealthy food intake respectively.Results: The prevalence of overweight was 19% and obesity 6%. Physically active females were 41%, as defined by the American College of Sports Medicine (ACSM) recommendations for moderate physical activity (Haskell et al. 2007). Concerning vigorous physical activity, only 17%, of the subjects met the current recommendations. According to WHO’s recommendations for physical activity levels 55% were minimally active and 12% active. Significant predictors for moderate/vigorous physical activity were found to be proximity to parks, mothers’ education (positive relation), lack of knowledge, and number of brothers (negative relation). It also emerged that 88% of the participants had unhealthy food intake with the fathers’ level of education as the only significant predictor.Conclusion: A minority of the subjects met with current recommendations for physical activity. Intervention studies and implementation of national nutritional guidelines are needed and should be integrated in the education of the adolescents and young adults.
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29.
  • Khalaf, Atika, et al. (author)
  • Prevalence and determinants of obesity and physical inactivity among female university students in South Western Saudi Arabia
  • 2011
  • Conference paper (other academic/artistic)abstract
    • Rationale: The prevalence of obesity in Saudi Arabia (KSA) is a growing challenge to public health, it may affect and be related to the levels of physical activity. The aim of this study was to examine the prevalence of overweight and obesity, physical activity, and unhealthy food intake among female university students in Saudi Arabia. In addition, determinants for levels of physical activity and unhealthy food intake were examined. Methods: This cross-sectional study included 663 female students in a university centre in KSA. Measures included anthropometric, socioeconomic, environmental, cultural, and life style factors such as physical activities, sedentary activities and eating habits. Logistic regressions were used to identify predictors of physical activity and unhealthy food intake respectively. Results: The prevalence of overweight was 19% and obesity 6%. Physically active females were 41%, as defined by the American College of Sports Medicine (ACSM) recommendations for moderate physical activity (Haskell et al. 2007). Concerning vigorous physical activity, only 17%, of the subjects met the current recommendations. According to WHO’s recommendations for physical activity levels 55% were minimally active and 12% active. Significant predictors for moderate/vigorous physical activity were found to be proximity to parks, mothers’ education (positive relation), lack of knowledge, and number of brothers (negative relation). It also emerged that 88% of the participants had unhealthy food intake with the fathers’ level of education as the only significant predictor. Conclusion: A minority of the subjects met with current recommendations for physical activity. Intervention studies and implementation of national nutritional guidelines are needed and should be integrated in the education of the adolescents and young adults.
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31.
  • Lemoine, J E, et al. (author)
  • Factor structure and psychometric properties of the Body Appreciation Scale-2 among adolescents and young adults in Danish, Portuguese, and Swedish
  • 2018
  • In: Body Image. - : Elsevier BV. - 1740-1445 .- 1873-6807. ; 26, s. 1-9
  • Journal article (peer-reviewed)abstract
    • In recent years, the study of body image shifted from focusing on the negative aspects to a more extensive view of body image. The present study seeks to validate a measure of positive body image, the Body Appreciation Scale-2 (BAS-2; Tylka & Wood-Barcalow, 2015a) in Denmark, Portugal, and Sweden. Participants (N = 1012) were adolescents and young adults aged from 12 to 19. Confirmatory factor analyses confirmed the one-dimensional factor structure of the scale. Multi-group confirmatory factor analyses indicated that the scale was invariant across sex and country. Further results showed that BAS-2 was positively correlated with self-esteem, psychological well-being, and intuitive eating. It was negatively correlated with BMI among boys and girls in Portugal but not in Denmark and Sweden. Additionally, boys had higher body appreciation than girls. Results indicated that the BAS-2 has good psychometric properties in the three languages.
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32.
  • Lensen, S., et al. (author)
  • A Randomized Trial of Endometrial Scratching before In Vitro Fertilization
  • 2019
  • In: New England Journal of Medicine. - 0028-4793. ; 380:4, s. 325-334
  • Journal article (peer-reviewed)abstract
    • BACKGROUND Endometrial scratching (with the use of a pipelle biopsy) is a technique proposed to facilitate embryo implantation and increase the probability of pregnancy in women undergoing in vitro fertilization (IVF). We conducted a pragmatic, multicenter, open-label, randomized, controlled trial. Eligible women were undergoing IVF (fresh-embryo or frozen-embryo transfer), with no recent exposure to disruptive intrauterine instrumentation (e.g., hysteroscopy). Participants were randomly assigned in a 1: 1 ratio to either endometrial scratching (by pipelle biopsy between day 3 of the cycle preceding the embryo-transfer cycle and day 3 of the embryo-transfer cycle) or no intervention. The primary outcome was live birth. A total of 1364 women underwent randomization. The frequency of live birth was 180 of 690 women (26.1%) in the endometrial-scratch group and 176 of 674 women (26.1%) in the control group (adjusted odds ratio, 1.00; 95% confidence interval, 0.78 to 1.27). There were no significant between-group differences in the rates of ongoing pregnancy, clinical pregnancy, multiple pregnancy, ectopic pregnancy, or miscarriage. The median score for pain from endometrial scratching (on a scale of 0 to 10, with higher scores indicating worse pain) was 3.5 (interquartile range, 1.9 to 6.0). Endometrial scratching did not result in a higher rate of live birth than no intervention among women undergoing IVF.
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