| 1. |
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| 2. |
- Asano, H., et al.
(author)
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Spectroscopic study of the Λ(1405) resonance via the d (K-, n) reaction at J-PARC
- 2019
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In: 13th International Conference on Hypernuclear and Strange Particle Physics, HYP 2018. - : AIP Publishing. - 9780735418721 ; 2130
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Conference paper (peer-reviewed)abstract
- The structure of the Λ(1405) hyperon is an important and long-standing issue related to the K̄-nucleus interaction. The J-PARC E31 experiment has been performed to investigate the Λ(1405) spectrum shape. Because it is hard to form the Λ(1405) directly by a K̄N scattering in free space, E31 uses the d(K-, n) reaction with an incident kaon momentum of 1 GeV/c. We will identify three final states - ς-π+, ς+π-, ς0π0-so that the isospin structure of hyperon resonance states produced can be decomposed. The first physics run of the E31 experiment was performed in 2016. To enhance the statistics of the data set, we have performed the second physics run in the beginning of 2018. During the second run of E31, around 3.9×1010 kaons impacted on the deuteron target.
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| 3. |
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| 4. |
- Yamaga, Takumi, et al.
(author)
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Study of the elementary (K -, n) reactions to search for the K NN bound state via the 3He (K -, n) reaction at J-PARC
- 2016
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In: XVIth International Conference on Hadron Spectroscopy, Hadron 2015. - : Author(s). - 9780735413894 ; 1735
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Conference paper (peer-reviewed)abstract
- We have searched for the simplest kaonic nuclear state, K̄NN, using the in-flight 3He (K-, n) reaction at the J-PARC hadron experimental facility. In the semi-inclusive neutron missing-mass spectrum at θnlab=0°, an excess of yield was observed just below the K- pp mass-threshold, which cannot be explained by any elementary reactions [PTEP 2015, 061D01]. To understand the missing-mass spectrum of 3He (K-, n) X, we investigated the elementary (K-, n) reactions using hydrogen and deuterium targets. The p (K-, n) X missing-mass spectrum was well described by the charge-exchange reaction. However, in the d (K-, n) X spectrum, we observed an excess of yield just below the K- p mass-threshold, which was similar to that in the 3He (K-, n) X spectrum.
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| 5. |
- Sada, Y., et al.
(author)
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Structure near the K- + p + p threshold in the in-flight 3He(K-, Λp)n reaction
- 2016
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In: Progress of Theoretical and Experimental Physics. - : Oxford University Press (OUP). - 2050-3911. ; 2016:5
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Journal article (peer-reviewed)abstract
- To search for an S = -1 di-baryonic state which decays toΛp, the 3He(K-,Λp)nmissing reaction was studied at 1.0 GeV/c. Unobserved neutrons were kinematically identified from the missing mass MX of the 3He (K-,Λp) X reaction in order to have a large acceptance for the Λpn final state. The observed Λpn events, distributed widely over the kinematically allowed region of the Dalitz plot, establish that the major component comes from a three-nucleon absorption process. A concentration of events at a specific neutron kinetic energy was observed in a region of low momentum transfer to the Λp. To account for the observed peak structure, the simplest S-wave polewas assumed to exist in the reaction channel, having a Breit-Wigner formin energy and with a Gaussian form factor. A minimum X2 method was applied to deduce its mass, MX = 2355+6 -8 (stat.) ±12 (syst.)MeV/c2, and decay width, γX = 110+19 -17 (stat.) ±27 (syst.)MeV/c2, respectively. The form factor parameter QX ∼ 400MeV/c implies that the range of the interaction is about 0.5 fm.
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| 6. |
- Kou, I, et al.
(author)
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A multi-ethnic meta-analysis confirms the association of rs6570507 with adolescent idiopathic scoliosis
- 2018
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In: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 8:1, s. 11575-
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Journal article (peer-reviewed)abstract
- Adolescent idiopathic scoliosis (AIS) is the most common type of spinal deformity and has a significant genetic background. Genome-wide association studies (GWASs) identified several susceptibility loci associated with AIS. Among them is a locus on chromosome 6q24.1 that we identified by a GWAS in a Japanese cohort. The locus is represented by rs6570507 located within GPR126. To ensure the association of rs6570507 with AIS, we conducted a meta-analysis using eight cohorts from East Asia, Northern Europe and USA. The analysis included a total of 6,873 cases and 38,916 controls and yielded significant association (combined P = 2.95 × 10−20; odds ratio = 1.22), providing convincing evidence of the worldwide association between rs6570507 and AIS susceptibility. In silico analyses strongly suggested that GPR126 is a susceptibility gene at this locus.
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| 7. |
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| 8. |
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| 9. |
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| 10. |
- Ogura, Y, et al.
(author)
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An international meta-analysis confirms the association of BNC2 with adolescent idiopathic scoliosis
- 2018
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In: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 8:1, s. 4730-
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Journal article (peer-reviewed)abstract
- Adolescent idiopathic scoliosis (AIS) is a common spinal deformity with the prevalence of approximately 3%. We previously conducted a genome-wide association study (GWAS) using a Japanese cohort and identified a novel locus on chromosome 9p22.2. However, a replication study using multi-population cohorts has not been conducted. To confirm the association of 9p22.2 locus with AIS in multi-ethnic populations, we conducted international meta-analysis using eight cohorts. In total, we analyzed 8,756 cases and 27,822 controls. The analysis showed a convincing evidence of association between rs3904778 and AIS. Seven out of eight cohorts had significant P value, and remaining one cohort also had the same trend as the seven. The combined P was 3.28 × 10−18 (odds ratio = 1.19, 95% confidence interval = 1.14–1.24). In silico analyses suggested that BNC2 is the AIS susceptibility gene in this locus.
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| 11. |
- Abudurexiti, A, et al.
(author)
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Taxonomy of the order Bunyavirales: update 2019
- 2019
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In: Archives of virology. - : Springer Science and Business Media LLC. - 1432-8798 .- 0304-8608. ; 164:7, s. 1949-1965
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Journal article (peer-reviewed)
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| 12. |
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| 13. |
- Tang, C A, et al.
(author)
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Fracture spacing in layered materials and pattern transition from parallel to polygonal fractures
- 2006
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In: Physical Review E. Statistical, Nonlinear, and Soft Matter Physics. - 1539-3755 .- 1550-2376. ; 73:5, s. 056120-28
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Journal article (peer-reviewed)abstract
- We perform three-dimensional simulations of fracture growth in a three-layered plate model with an embedded heterogeneous layer under horizontal biaxial stretch (representing stretch from directional to isotropic) by the finite element approach. The fractures develop under a quasistatical, slowly increasing biaxial strain. The material inhomogeneities are accounted for by assigning each element a failure threshold that is defined by a given statistical distribution. A universal scale law of fracture spacing to biaxial strain in terms of principal stress ratio is well demonstrated in a three-dimensional fashion. The numerically obtained fracture patterns show a continuous pattern transition from parallel fractures, laddering fracture to polygonal fractures, which depends strongly on the far-field loading conditions in terms of principal stress ratio ......
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| 14. |
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| 15. |
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| 16. |
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| 17. |
- Duarte, Margarida Taborda, et al.
(author)
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Microstructural modeling approach applied to rock material
- 2005
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In: Journal of materials engineering and performance (Print). - : Springer Science and Business Media LLC. - 1059-9495 .- 1544-1024 .- 0000-0000. ; 14:1, s. 104-111
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Journal article (peer-reviewed)abstract
- The importance of the microstructural parameters in rock mechanical behavior has been investigated by several authors. Moreover, the Weibull statistical model has been used to characterize the heterogeneity of several materials on the basis of the concept that the microscopic defects within the material determine their mechanical strength. The modeling of different rocks is a topic that is fundamental for the prediction of rock fragmentation. In this article, the analysis of rock microstructure is performed using the microstructural modeling approach, which consists of the simplification, quantification, and modeling of the main properties of rock microstructure. The grain size, grain shape, and microcracks are modeled by means of statistical density functions, namely, Cauchy, chi-squared, exponential, extreme value, gamma, Laplace, normal, uniform, and Weibull. It is found that the Weibull distribution is the most appropriate statistical model of the grain size and grain shape, when compared with the other eight statistical models. Regarding microcracks, the results show that the gamma distribution is the most appropriate model. The Weibull and gamma distributions are then used to analyze the heterogeneity of the microstructure. This is done by comparison of the statistical models of each microstructural property evaluated in several thin sections of the same rock. It is found that with respect to grain size and grain shape, the rock is homogeneous, while the size distribution of the microcracks shows a clear trend toward less homogeneity. The microstructural modeling approach is important for modeling, characterizing, and analyzing the microstructure of rock material. Among other applications, it can be used to explain differences in the mechanical behavior obtained in testing several specimens.
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| 18. |
- Fan, W., et al.
(author)
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Investigation of magnetization dynamics damping in Ni80Fe20/Nd-Cu bilayer at room temperature
- 2018
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In: AIP Advances. - : American Institute of Physics (AIP). - 2158-3226. ; 8:5
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Journal article (peer-reviewed)abstract
- Focusing on the Ni80Fe20 (Py)/Nd-Cu bilayers, the magnetization dynamic damping from spin pumping effect is investigated systematically by doping itinerant Cu in rear earth metal Nd. Various Ta/Py/Nd1-xCux/Ta/Si films with x = 0%, 16%, 38%, 46% and 58% are prepared by magnetron sputtering. For every content of Cu, the thickness of Nd-Cu layer is changed from 1 nm to 32 nm. The damping coefficient increases with increasing the thickness of Nd-Cu layer, which shows the trend of the spin pumping behavior. Also, with increasing Cu concentration in the Nd-Cu layer, the damping coefficient decreases, implying that the spin-orbit coupling in Nd-Cu layer is indeed cut down by high itinerant of Cu dopants. It is interesting that the spin diffusion length (λSD) in the Nd-Cu layer for different Cu dopants is not found to increase monotonously.
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| 19. |
- Kou, R. H., et al.
(author)
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Charge transfer-tuned magnetism in Nd-substituted Gd5Si4
- 2018
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In: AIP Advances. - : AIP Publishing. - 2158-3226. ; 8:12
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Journal article (peer-reviewed)abstract
- We report a charge-transfer mechanism in tuning of magnetism of Nd-substituted Gd5-xNdxSi4 (x=1 and 2.5) compounds. The X-ray absorption near edge structure measurements demonstrated that Nd substitutions for Gd induce charge transfer of 5d electrons from Gd to Nd. The charge transfer weakens spin-orbital coupling of Gd but strengthens that of Nd. Consequently, the magnetization responses of the substituted compounds to low magnetic fields are increased while their saturation magnetization is reduced. Electronic structure calculations showed that the charge transfer stabilizes a ferromagnetic and a ferrimagnetic structure in the compounds with x = 1 and 2.5, respectively, but that it does not change the 5d-3p hybridization significantly. It is suggested that the charge transfer of 5d electrons may occur in other rare earth-substituted Gd5Si4 compounds allowing for tuning of their magnetism.
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| 20. |
- Liu, H. Y., et al.
(author)
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Numerical modelling of the heterogeneous rock fracture process using various test techniques
- 2007
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In: Rock Mechanics and Rock Engineering. - : Springer Science and Business Media LLC. - 0723-2632 .- 1434-453X. ; 40:2, s. 107-144
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Journal article (peer-reviewed)abstract
- A series of numerical tests including both rock mechanics and fracture mechanics tests are conducted by the rock and tool (R-T2D) interaction code coupled with a heterogeneous masterial model to obtain the physical-mechanical properties and fracture toughness, as well as to simulate the crack initiation and propagation, and the fracture progressive process. The simulated results not only predict relatively accurate physical-mechanical parameters and fracture toughness, but also visually reproduce the fracture progressive process compared with the experimental and theoretical results. The detailed stress distribution and redistribution, crack nucleation and initiation, stable and unstable crack propagation, interaction and coalescence, and corresponding load-displacement curves can be proposed as benchmarks for experimental study and theoretical research on crack propagation. It is concluded that the heterogeneous material model is reasonable and the R-T2D code is stable, repeatable and a valuable numerical tool for research on the rock fracture process.
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| 21. |
- Liu, H.Y., et al.
(author)
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Numerical studies on bit-rock fragmentation mechanisms
- 2008
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In: International Journal of Geomechanics. - 1532-3641 .- 1943-5622. ; 8:1, s. 45-67
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Journal article (peer-reviewed)abstract
- The rock fragmentation process induced by a single button-bit, two neighboring button-bits, and multiple button-bits are numerically studied using the rock and tool interaction code (R-T2D). Through this study, a better understanding of the bit-rock fragmentation mechanisms is gained. It is found that side crack is initiated from the crushed zone or bifurcated from Hertzian crack to propagate approximately parallel to the free rock surface but in a curvilinear path driven by the tensile stress associated with the expansion of the crushed zone during the loading process. In the crushed zone, the mechanism of side crack is mixed tensile and shear failure, but outside the crushed zone, the dominant mechanism of side crack is tensile failure. A semiempirical and semitheoretical relationship among the side crack length, the drilled rock property, and the drilling force is formulated to approximately predict the side crack length. In the simultaneous loading, the interaction and coalescence of side cracks induced by the neighboring button-bits with an optimum line spacing enable formation of largest rock chips, control of the direction of subsurface cracks and a minimum total specific energy consumption. A formula is derived to determine the optimum line spacing on the basis of the drilled rock properties, the diameter and shape of the button-bit, and the drilling conditions. In the rock fragmentation by multiple button-bits, most of the rock between the neighboring button-bits is chipped as a result of the coalescence of side cracks. In the remaining rock, the intensely crushed zones and significant extensional cracks are observed adjacent to the sidewall and the inside of the borehole. Fragment side distribution shows more than 80% of the fragments are fines in the crushed zones as well as the cracked zones, the large fragments be indeed observed, which are the big chips caused by the coalescence of side cracks.
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| 22. |
- Liu, H.Y., et al.
(author)
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Numerical studies on the failure process and associated microseismicity in rock under triaxial compression
- 2004
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In: Tectonophysics. - : Elsevier BV. - 0040-1951 .- 1879-3266. ; 384:1-4, s. 149-174
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Journal article (peer-reviewed)abstract
- In this paper, firstly the mesoscopic elemental mechanical model for elastic damage is developed and implemented into the rock and tool interaction code (R-T (super 2D) ). Then the failure processes of a heterogeneous rock specimen subjected to a wide variety of confining pressures (0-80 MPa) are numerically investigated using the R-T (super 2D) code. According to the simulated results, on the one hand, the numerical simulation reproduced some of the well-known phenomena observed by previous researchers in triaxial tests. Under uniaxial compression, rock failure is caused by a combination of axial splitting and shearing. Dilatancy and a post-failure stage with a descending load bearing capacity are the prominent characteristics of the failure. As the confining pressure increases, the extension of the failed sites is suppressed, but the individual failure sites become dense and link with each other to form a shear fracture plane. Correspondingly, the peak strength, the residual strength and the shear fracture plane angle increase, but the brittleness decreases. When the confining pressure is high enough, the specimen behaves in a plastic manner and a narrow shear fracture plane leads to its failure. The prominent characteristics are volume condensation, ductile cataclastic failure, and a constant load bearing capacity with increasing strain. On the other hand, the numerical simulation revealed some new phenomena. The highest microseismicity events occur in the post-failure stage instead of the maximal stress, and most of the microseismicity energies are released in the failure localization process. As the confining pressure increases, the microseismicity events in the non-linear deformation stage increase dramatically and the ratio between the energies dissipated at the non-linear deformation stage and those dissipated in the whole loading process increases correspondingly. Therefore, it is concluded that the developed mesoscopic elemental mechanical model for elastic damage is able to reproduce accurately the failure characteristics in loading rock specimens under triaxial conditions, and the numerical modelling can furthermore obtain some new clarifications of the rock fracture process.
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| 23. |
- Tang, C. A., et al.
(author)
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Numerical investigation of particle breakage as applied to mechanical crushing—Part I: Single-particle breakage
- 2001
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In: International Journal of Rock Mechanics And Mining Sciences. - 1365-1609 .- 1873-4545. ; 38:8, s. 1147-1162
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Journal article (peer-reviewed)abstract
- A numerical approach to particle breakage is applied using the Rock Failure Process Analysis code, RFPA (super 2D) . The numerical tool is validated by simulating the Brazilian test with a two-dimensional disk sample. Then two irregularly shaped particles with an exact geometry and exact mechanical properties are numerically modelled to investigate their breakage behaviour under unconfined and confined loading conditions. The numerical results indicate that the dominant mode of failure is catastrophic splitting and progressive crushing, which mainly depends on the loading conditions with respect to confinement. The analysis of the load-displacement curves obtained from the simulations suggests a brittle-ductile transition between the two cases. The lateral constraint increases the initial stiffness and the maximum breakage strength of the particle. Most of the energy released during the failure process comes from the crushing of highly stressed areas, particularly, in the vicinity of the contact points where a crushed zone forms. It is also found that the particle shape governs the breakage strength in addition to the material properties themselves, and that the heterogeneity of the particles governs the fracture propagation paths
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| 24. |
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| 25. |
- Wang, ZC, et al.
(author)
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Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd
- 2016
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In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 7, s. 12846-
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Journal article (peer-reviewed)abstract
- Gene expression data are accumulating exponentially in public repositories. Reanalysis and integration of themed collections from these studies may provide new insights, but requires further human curation. Here we report a crowdsourcing project to annotate and reanalyse a large number of gene expression profiles from Gene Expression Omnibus (GEO). Through a massive open online course on Coursera, over 70 participants from over 25 countries identify and annotate 2,460 single-gene perturbation signatures, 839 disease versus normal signatures, and 906 drug perturbation signatures. All these signatures are unique and are manually validated for quality. Global analysis of these signatures confirms known associations and identifies novel associations between genes, diseases and drugs. The manually curated signatures are used as a training set to develop classifiers for extracting similar signatures from the entire GEO repository. We develop a web portal to serve these signatures for query, download and visualization.
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| 26. |
- Zhang, Z. X., et al.
(author)
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Effects of loading rate on rock fracture
- 1999
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In: International Journal of Rock Mechanics And Mining Sciences. - 1365-1609 .- 1873-4545. ; 36:5, s. 597-611
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Journal article (peer-reviewed)abstract
- By means of a wedge loading applied to a short-rod rock fracture specimen tested with the MTS 810 or SHPB (split Hopkinson pressure bar), the fracture toughness of Fangshan gabbro and Fangshan marble was measured over a wide range of loading rates, =10−2–106 MPa m1/2 s−1. In order to determine the dynamic fracture toughness of the rock as exactly as possible, the dynamic Moiré method and strain–gauge method were used in determining the critical time of dynamic fracture. The testing results indicated that the critical time was generally shorter than the transmitted wave peak time, and the differences between the two times had a weak increasing tendency with loading rates. The experimental results for rock fracture showed that the static fracture toughness KIc of the rock was nearly a constant, but the dynamic fracture toughness KId of the rock (≥104 MPa m1/2 s−1) increased with the loading rate, i.e. log(KId)=a log +b. Macroobservations for fractured rock specimens indicated that, in the section (which was perpendicular to the fracture surface) of a specimen loaded by a dynamic load, there was clear crack branching or bifurcation, and the higher the loading rate was, the more branching cracks occurred. Furthermore, at very high loading rates (≥106 MPa m1/2 s−1) the rock specimen was broken into several fragments rather than only two halves. However, for a statically fractured specimen there was hardly any crack branching. Finally, some applications of this investigation in engineering practice are discussed.
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