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  • Stahl, Andreas, et al. (author)
  • Lipid metabolites in the pathogenesis and treatment of neovascular eye disease.
  • 2011
  • In: The British journal of ophthalmology. - : BMJ. - 0007-1161. ; 95:11, s. 1496-1501
  • Journal article (peer-reviewed)abstract
    • Lipids and lipid metabolites have long been known to play biological roles that go beyond energy storage and membrane structure. In age-related macular degeneration and diabetes, for example, dysregulation of lipid metabolism is closely associated with disease onset and progression. At the same time, some lipids and their metabolites can exert beneficial effects in the same disorders. This review summarises our current knowledge of the contributions of lipids to both the pathogenesis and treatment of neovascular eye disease. The clinical entities covered are exudative age-related macular degeneration, diabetic retinopathy and retinopathy of prematurity, with a special emphasis on the potential therapeutic effects of ω3- (also known as n-3) polyunsaturated fatty acids.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Hellström, Ann, 1959 (1)
Chen, Jing (1)
Stahl, Andreas (1)
Smith, Lois E H (1)
Holz, Frank G. (1)
Chew, Emily (1)
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Sapieha, Przemyslaw (1)
Krohne, Tim U (1)
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University
University of Gothenburg (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year

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