| 1. |
- Vadeby, Anna, 1969-, et al.
(författare)
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Säker framkomlighet : sammanfattande slutrapport 2015
- 2016
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Föreliggande rapport redovisar övergripande resultat av fyra olika åtgärder som implementerats inomTrafikverkets projekt ”Säker framkomlighet” vilket haft som syfte att förbättra framkomlighet ochtrafiksäkerhet på främst befintliga tvåfältsvägar med hastighetsgräns 90 km/tim. Åtgärderna somstuderats är: frästa mitträfflor på 2-fältsvägar, vägrensräffling på motorväg, smala mötesfria vägar(”gles 2+1-väg med räcke”) och riktningsseparerade vägar (2+1 med målad/räfflad mitt).Resultaten visar att för samtliga åtgärder har trafiksäkerhetseffekterna varit positiva med minskningarav de dödade och svårt skadade trafikanterna. Vad gäller spårdjupstillväxt visar resultaten att mitträfflinginte har en kanaliserande effekt på trafiken och därmed påverkas inte heller spårbildningen.För mötesfria vägar är den årliga spårdjupsutvecklingen cirka 25 procent högre för mötesfri väg än förmotsvarande vanlig väg för årsdygnstrafik (ÅDT) > 8 000 fordon/dygn. För lägre ÅDT är skillnaden 10–15 procent.För riktningsseparerade vägar visar resultaten endast på högre spårdjupstillväxt för ÅDT över 8 000fordon/dygn. En studie om effekter och konsekvenser av olika räffeltyper avseende buller visar att detinte finns kända argument för att inte använda sinusräffla, men ytterligare studier kring effekten förförare av tunga fordon rekommenderas. Studien avseende framkomlighetseffekter visar att andelentung trafik är en viktig faktor att beakta i utformningen av mötesfria vägar.
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| 2. |
- Abbasian, Saeid, 1961-, et al.
(författare)
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Between Fire and Ice : Experiences of the Persian Fire Festival in a Nordic Setting
- 2020
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Ingår i: Sustainability. - Schweiz : MDPI. - 2071-1050. ; 12:24
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Tidskriftsartikel (refereegranskat)abstract
- This exploratory research seeks to gain insight into the visitors of Persian Fire Festival in Stockholm, their motivation, level of satisfaction and loyalty to the festival. The overall methodology is mixed methods consisting of participant observation and 280 completed online surveys including close-ended and open-ended questions. A Grounded theory analysis has been employed. The most important reason behind the participation has been to strive for the recognition of ethnic cultural identity; to keep the ancient culture alive; to maintain their ancestors’ legacy and transfer it to the next generation. Most of the visitors experienced positive feelings, showed satisfaction and loyalty, believed that the festival fulfilled their expectations and it should be celebrated officially every year. A minority showed dissatisfaction mostly due to the lack of accessibility to the event venue and might are not loyal to the festival. The first conclusion here is that these motivators are totally different than those mentioned by earlier research (e.g., escape, socialization, novelty, rest, prestige, excitement). Even though the desire to preserve the ancient culture and tradition is very strong, a lack of accessibility to the venue would constitute disloyalty and a barrier to re-attend in such a festival.
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| 3. |
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| 4. |
- Finnveden, Göran, et al.
(författare)
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Evaluation of integration of sustainable development in higher education in Sweden
- 2020
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Ingår i: International Journal of Sustainability in Higher Education. - : Emerald Group Publishing Limited. - 1467-6370 .- 1758-6739. ; 21:4, s. 685-698
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Tidskriftsartikel (refereegranskat)abstract
- Purpose Since 2006, higher education institutions (HEIs) in Sweden, should according to the Higher Education Act, promote sustainable development (SD). In 2016, the Swedish Government asked the Swedish higher education authority to evaluate how this study is proceeding. The authority chose to focus on education. This paper aims to produce a report on this evaluation. Design/methodology/approach All 47 HEIs in Sweden were asked to write a self-evaluation report based on certain evaluation criteria. A panel was appointed consisting of academics and representatives for students and working life. The panel wrote an evaluation of each HEI, a report on general findings and recommendations, and gave an overall judgement of each HEI in two classes as follows: the HEI has well-developed processes for integration of SD in education or the HEI needs to develop their processes. Findings Overall, a mixed picture developed. Most HEIs could give examples of programmes or courses where SD was integrated. However, less than half of the HEIs had overarching goals for integration of SD in education or had a systematic follow-up of these goals. Even fewer worked specifically with pedagogy and didactics, teaching and learning methods and environments, sustainability competences or other characters of education for SD. Overall, only 12 out of 47 got a higher judgement. Originality/value This is a unique study in which all HEIs in a country are evaluated. This provides unique possibilities for identifying success factors and barriers. The importance of the leadership of the HEIs became clear.
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| 5. |
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| 6. |
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| 7. |
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| 8. |
- Jarrick, Simon, 1977-, et al.
(författare)
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Immunoglobulin A nephropathy and ischemic heart disease : a nationwide population-based cohort study
- 2021
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Ingår i: BMC Nephrology. - : BioMed Central (BMC). - 1471-2369. ; 22:1
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Chronic kidney disease has been linked to cardiovascular disease and specifically ischemic heart disease (IHD), but large-scale population data in patients with immunoglobulin A nephropathy (IgAN) are missing.OBJECTIVE: To examine absolute and relative risks for IHD in patients with IgAN.METHODS: Population-based register-based cohort study in Sweden. We identified 3945 patients with biopsy-verified IgAN, and 19,272 age- and sex-matched reference individuals from the general population. To reduce residual confounding from genetic factors and early environmental factors we carried out secondary analyses, where we compared 3039 IgAN patients with 6729 siblings, whereas a spousal analysis consisted of 2377 married couples where one of the spouses had IgAN. Data on IHD and end-stage renal disease (ESRD) were retrieved from the nationwide Patient Register. Cox regression estimated hazard ratios (HRs) adjusted for matching variables, education, country of birth, cancer, diabetes mellitus, and other systemic inflammatory diseases.RESULTS: During a follow-up of 55,527 person-years (py; mean follow-up 14.1 years), 371 patients (9.4%) with IgAN developed IHD (6.7/1000 py), compared with 1070 (5.6%) in 287,677 py in reference individuals (3.7/1000 py). The corresponding adjusted HR was 1.86 (95%CI = 1.63-2.13), equivalent to one extra case of IHD per 34 IgAN patients followed-up for 10 years. HRs were similar in men and women with IgAN, but higher in the first year after diagnosis and in patients born outside the Nordic countries. Patients with IgAN were at increased risk of IHD also compared to siblings (HR = 2.07; 95%CI = 1.62-2-64) and spouses (HR = 1.91; 95%CI = 1.40-2.61).CONCLUSIONS: In this nationwide population-based study, patients with IgAN were at an 86% increased risk of future IHD.
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| 9. |
- Kemani, Mike K, et al.
(författare)
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Factor structure and internal consistency of a Swedish version of the Pain Catastrophizing Scale.
- 2019
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Ingår i: Acta anaesthesiologica Scandinavica. - : Wiley. - 1399-6576 .- 0001-5172. ; 63:2, s. 259-266
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Tidskriftsartikel (refereegranskat)abstract
- Pain catastrophizing is highly relevant to assess in the context of long-standing pain. The Pain Catastrophizing Scale (PCS) is a well-established questionnaire used to measure catastrophizing in individuals with long-standing pain. So far, no Swedish translation has been evaluated in regard to validity and reliability. The aims of this study were to translate the PCS questionnaire from English to Swedish, and to investigate its construct validity (face, content, and structural validity) and reliability (internal consistency).We translated the original English version of the PCS to Swedish and collected item responses from 194 persons suffering from primarily long-standing musculoskeletal pain. We used confirmatory factor analysis to evaluate structural validity, and tested the model fit of a one-factor model, an oblique two-factor model, and an oblique three-factor model. We evaluated the measure's reliability in regard to internal consistency calculated with Cronbach's alpha.A three-factor model comprising a four-item rumination factor, a three-item magnification factor, and a six-item helplessness factor provided the best fit to the data. Internal consistency was adequate and Cronbach's α was 0.92 for the entire scale, 0.84 for the rumination subscale; 0.69 for the magnification subscale, and 0.89 for the helplessness subscale.The results indicated adequacy of a three-factor solution and the questionnaire's internal consistency, and provide initial support for the structural validity and internal consistency of a Swedish version of the PCS. Future studies should replicate the study in larger samples and extend the current evaluation in regard to validity and reliability.
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| 10. |
- Kharlamova, N., et al.
(författare)
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False Positive Results in SARS-CoV-2 Serological Tests for Samples From Patients With Chronic Inflammatory Diseases
- 2021
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Ingår i: Frontiers in Immunology. - : Frontiers Media SA. - 1664-3224. ; 12
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Tidskriftsartikel (refereegranskat)abstract
- Patients with chronic inflammatory diseases are often treated with immunosuppressants and therefore are of particular concern during the SARS-CoV-2 pandemic. Serological tests will improve our understanding of the infection and immunity in this population, unless they tests give false positive results. The aim of this study was to evaluate the specificity of SARS-Cov-2 serological assays using samples from patients with chronic inflammatory diseases collected prior to April 2019, thus defined as negative. Samples from patients with multiple sclerosis (MS, n=10), rheumatoid arthritis (RA, n=47) with or without rheumatoid factor (RF) and/or anti-cyclic citrullinated peptide antibodies (anti-CCP2) and systemic lupus erythematosus (SLE, n=10) with or without RF, were analyzed for SARS-CoV-2 antibodies using 17 commercially available lateral flow assays (LFA), two ELISA kits and one in-house developed IgG multiplex bead-based assay. Six LFA and the in-house validated IgG assay correctly produced negative results for all samples. However, the majority of assays (n=13), gave false positive signal for samples from patients with RA and SLE. This was most notable in samples from RF positive RA patients. No false positive samples were detected in any assay using samples from patients with MS. Poor specificity of commercial serological assays could possibly be, at least partly, due to interfering antibodies in samples from patients with chronic inflammatory diseases. For these patients, the risk of false positivity should be considered when interpreting results of the SARS-CoV-2 serological assays.
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| 11. |
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Kreativt skrivande och kritiskt tänkande i genusvetenskap
- 2014
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- Den här skriften handlar om kreativt skrivande och kritiskttänkande, två centrala kunskapsområden för genusforskningoch feministisk forskning idag. Inom genusvetenskapen, menockså i den genusforskning som bedrivs inom ramen för andraämnesområden, har kritik av vetenskapliga metoder och utgångspunktervarit grundläggande för stora delar av verksamheten.Ifrågasättandet av en universell eller objektiv vetenskaputgör själva grunden i genusvetenskapens curriculum. Som endel i en sådan vetenskapskritisk och vetenskapsutvecklandeverksamhet ingår det kreativa vetenskapliga skrivande, och kritiska tänkande, som utvecklats inom genusvetenskapen.
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| 12. |
- Ljungcrantz, Desireé, 1982-
(författare)
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Skrubbsår : Berättelser om ur hiv föreställs och erfars i samtida Sverige
- 2017
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Avhandlingen är en tvärvetenskaplig kulturstudie som utforskar föreställningar om och erfarenheter av hiv som kronisk sjukdom i Sverige under 2005–2014. Analysen av ett antal hiv-berättelser sker tillsammans med en teoretisk sammanflätning i form av den queera sårbarhetens och sjukdomens fenomenologi, samt genom de feministiska figurationerna hiv-tröskeln, skrubbsår, plåster och gruskorn. Materialet utgörs av djupintervjuer, autofiktiva texter och populärkulturella representationer. I djupintervjuer med personer som har hiv och i autofiktiva texter undersöks när och hur hiv görs och blir påtagligt i vardagslivet. Genom läsningar av de populärkulturella berättelserna Hur kunde hon?, Ophelias resa, Mitt positiva liv och Positiv undersöker avhandlingen hur protagonisterna och hiv gestaltas, vad som bygger dramaturgin samt hur normaliserande skildringar riskerar att (åter)skapa normativa gränser. Förhandlingar med normlinjer berör återkommande respektabilitet och begäret att framstå som en lyckad och lycklig individ, men även att ha ett levbart liv. Hiv-berättelser innehåller återkommande känslor som rädsla, skam och mononormativ melankoli. De utgör skrubbsår skapade i mötet med andra personer, samhällsinstitutioner och de föreställningar om hiv som finns i samhället. Likt gruskorn skrubbar föreställningarna oss. Det medför olika former av undvikande och ensamhetsorienteringar. Plåster, det vill säga individuella strategier av att exponera hiv och att distansera sig från den yttre blicken på självet görs tillsammans med och skapar känslor såsom lättnad, stolthet och ilska. Skrubbsår erbjuder en diskussion kring vardagligt hiv-görande, hur vi blir med hiv tillsammans med andra personer, normer, institutioner och samhällets skam- och kontrollmekanismer, samt hur känslor samskapar hiv. Genom ett poetiskt och skönlitterärt skrivande utgör scener och fiktiva karaktärer, baserade på intervjuer, och den autofiktiva alter-egoberättaren Desideria ett icke-distanserat och kännbart gestaltande av det relationella hiv-blivandet.
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| 13. |
- Lundberg, Anna, 1969-
(författare)
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Allt annat än allvar : den komiska kvinnliga grotesken i svensk samtida skrattkultur
- 2008
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Avhandlingen tar avstamp i ett möte mellan å ena sidan Michail Bachtins begrepp skrattkultur och hans positiva och uppvärderande framställning av grotesk estetik, och å andra sidan feministisk och queer teoribildning. Avhandlingen utgör en tvärvetenskaplig kulturstudie av svensk samtida skrattkultur, Mer specifikt fokuseras framställningar av kön, kropp och sexualitet. Texten bygger på närläsning av tre empiriska sammanhang: Först analyseras de radiosketcher som skrevs och framfördes under 1990-talets andra hälft av komikerna Åsa Asptjärn och Gertrud Larsson, som bildade duon ”Åsa och Gertrud”. Sketcherna sändes som ett inslag i de feministiska färgade radioprogrammet Radio Ellen och Freja! i public servicekanalen P1. Avhandlingen lyfter fram det sätt på vilket Åsa och Gertrud skapar komik genom att kombinera nyhetsstoff, feministisk vinkel och det närgångna förhållningssätt till kropp, kön, sexualitet och omvärld som är typiskt för skrattkulturens framställningar. Högtstående företeelser framställs genom det intima och närgånga perspektivet. Åsa och Gertruds komik är innovativ. Den kan, tack vare att det visuella är frånvarande i radions form, låta skrattkulturens groteska fantasi få ett förhållandevis fritt spelrum. Det leder till att stoffet som behandlas ofta framträder på ett helt nytt sätt. Därefter analyseras Prideparaden som sedan 1998 årligen äger rum i Stockholm. Paraden och dess hav av kroppar i tåget och i publiken läses utifrån en kombination av lust, komik och politik. Slutligen presenteras en läsning av den svenska situationskomedin Sally. Den sändes i TV under 1999 i båda public servicekanalerna. Huvudpersonen Sally, spelad och skapad av skådespelerskan Maria Lundqvist, är en skrattkulturell figur vars komik och groteskeri ställer en rad vanemässiga föreställningar om kön, kropp och sexualitet på ända. I dessa tre närläsningar av materialets komiska och groteska framställning av kön, kropp och sexualitet pekar avhandlingen på den potential som finns i mötet mellan å ena sidan komikens och skrattkulturens inslag av lust, självsvåldig meningskonstruktion och nonsens, och å andra sidan ett feministiskt och queert färgat perspektiv.
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| 14. |
- Lundberg, Anna, 1969-
(författare)
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Athena Student Forum
- 2004
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Annan publikation (populärvet., debatt m.m.)abstract
- Artikel om Athena Student Forum, i AOIFE news, 1:2004
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| 15. |
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| 16. |
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| 17. |
- Lundberg, Anna, 1969-
(författare)
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Emotional labor
- 2014
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Ingår i: Att delta på djupet<em> </em>. - Linköping : Ung scen/öst. - 9789163754401
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Bokkapitel (populärvet., debatt m.m.)
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| 18. |
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| 19. |
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| 20. |
- Lundberg, Anna, 1969-, et al.
(författare)
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Genusvetenskapens pedagogik : Mellan erfarenhetsbaserat lärande och vetenskapligt samtal
- 2012
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Ingår i: Genusvetenskapens pedagogik och didaktik. - Göteborg : Nationella sekretariatet för genusforskning. - 9789198080209 ; , s. 11-18
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Den här skriften handlar om genusvetenskapens pedagogiska och didaktiska verksamhet. Den handlar om vad som händer i det genusvetenskapliga klassrummet, hur lärandeprocesserna och utmaningarna ser ut och vad som betraktas som viktiga pedagogiska ställningstaganden. Den handlar om hur lärare i genusvetenskap på olika sätt arbetar för att skapa goda villkor för lärande, för alla, och den handlar om vad som är svårt i maktkritiska lärandeprocesser och vad som är den genusvetenskapliga pedagogikens styrkor.
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| 21. |
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| 22. |
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| 23. |
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| 24. |
- Lundberg, Anna, 1969-, et al.
(författare)
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Konsten att göra konst tillsammans : Om arbetet med "Vad ska vi göra?" på ung scen/öst
- 2013
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Ingår i: Nu vill jag prata!. - Stockholm : Stockholm universitets förlag. - 9789176566848 ; , s. 191-201
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Bokkapitel (populärvet., debatt m.m.)abstract
- Barnperspektiv och delaktighet är begrepp som – i svallvågorna efter FN:s konvention om barnets rättigheter – under senare år starkt inspirerat barnkulturen i både forskning och praktik. Perspektiven i texterna är många och skiftande. En författare beskriver förskolebarns lek som förhandlingsarena, en annan om hur vuxna lyssnar (eller inte) till barns röster i skolans värdepedagogiska arbete. Vad vill barn veta när de själva får fråga i filosofiska samtal? Läsaren får ta del av vad barn berättar om i Kamratpostens insändare. Några författare tar upp hur barndomsideal iscensätts och vad barn säger, känner och gör i nöjesparker och i Science Center samt hur barn involveras som medforskare inom olika forskningsfält.
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| 25. |
- Lundberg, Anna, 1969-, et al.
(författare)
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Kreativt skrivande och kritiskt tänkande i genusvetenskap
- 2014
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Ingår i: Kreativt skrivande och kritiskt tänkande i genusvetenskap. - Göteborg : Nationella sekretariatat för genusforskning. - 9789198080230 ; , s. 9-16
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 26. |
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| 27. |
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| 28. |
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| 29. |
- Lundberg, Anna, 1969-, et al.
(författare)
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Med passionen som drivkraft : En intersektionell analys av genusvetenskap, de studerande och arbetslivet
- 2014
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Ingår i: Tidskrift för Genusvetenskap. - : Föreningen Tidskrift för genusvetenskap. - 1654-5443 .- 2001-1377. ; 35:1, s. 49-71
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Tidskriftsartikel (refereegranskat)abstract
- Based on a national Swedish survey among former gender studies students followed by focus group interviews, this article investigates the students’ perspectives on gender studies and work. We ask how they understand their education in between generic critical knowledge and the labor market. How can the students’ backgrounds and talk about gender studies and work be understood intersectionally? What does it mean for the future of gender studies? The analysis is based on intersectional subject positions as developed by Dorthe Staunæss (2003) and compares the results with other critical feminist studies of higher education (Ahmed 2012; Berggren 2006; Mählck 2013; Orupabo 2014). The analytical method uses the concepts “gap” (Åse 2000), ”in sync” (Staunæss 2010) and “comfortable” (Ahmed 2010) in order to understand the contradicting results of the survey and talk in the focus groups. In our analysis we discuss the gaps the students identify between their studies and their experiences of finding work on the labor market as both significant for the humanities and social sciences in general and as specific for gender studies. The gender studies students are however employed and find their education useful on the labor market, a success that they also ascribe (partly) to their privileged background in terms of class and ethnicity. Among the participants persons with academically educated parents and parents born in Sweden were over-represented. The article also discusses what this skewed participation in gender studies education may mean for the discipline and the labor market for gender studies students. Finally it proposes four directions for the future development of gender studies.
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| 30. |
- Lundberg, Anna, 1969-
(författare)
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Ner genom kaninhålet
- 2013
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Ingår i: Teatertidningen. - Stockholm : Ekonomiska föreningen Nya teatertidningen. - 1101-9107. ; :5, s. 16-17
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 31. |
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| 32. |
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| 33. |
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| 34. |
- Lundberg, Anna, 1969-
(författare)
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“Will We be Tested on This?” : Schoolgirls, Neoliberalism and the Comic Grotesque in Swedish Contemporary Youth Theatre
- 2013
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Ingår i: Culture Unbound. - : Linköping University Electronic Press. - 2000-1525. ; 5:11, s. 133-152
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Tidskriftsartikel (refereegranskat)abstract
- This article is based on an ethnographic participation study of the production of a play called All about the ADHD and A+ Children of Noisy Village (Ännu mer om alla vi ADHD- och MVG-barn i Bullerbyn) staged at one of Sweden’s most prom-inent playhouses for children’s and youth theatre: ung scen/öst. Within the familiar setting of the classroom, the play takes on the challenging task of questioning and scrutinizing the complex and tangled situation of contemporary neoliberal ideas and practices, their connections to capitalism and their impact on everyday school-life. This in front of an audience consisting mainly of individuals who were not even born at the time when the political map was radically re-drawn in Berlin in 1989, and who have grown up during a period when neoliberal governance has gained increasing influence in Swedish culture and society. The play mediates its dense, political content and its descriptions of teenagers’ everyday lives through a large portion of good old-fashioned entertainment, with music, singing and bi-zarre, laughter-provoking situations. The main research question to be answered in the article is: In what ways are the abstract contemporary economic-political manifestations of power and govern-ance expressed in this good-humored play for youth, and how can this be read from a feminist perspective? Hence, the article circles around three nodes that in-tersect in various ways: theatre, economic-political issues and feminist perspec-tives. The theoretical framework of the article is primarily based on a merger be-tween, on the one hand, feminist social science and, on the other, feminist cultural analysis.
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| 35. |
- Lundberg, Frida E., et al.
(författare)
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Mortality in 43,598 men with infertility - a Swedish nationwide population-based cohort study
- 2019
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Ingår i: Clinical Epidemiology. - : DOVE Medical Press Ltd.. - 1179-1349. ; 11, s. 645-657
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Tidskriftsartikel (refereegranskat)abstract
- Background: Previous studies indicate a higher risk of comorbidity in men with infertility; however, research on mortality is scarce and the few studies that do exist have rarely differentiated between infertility and infertility-related diagnoses.Objective: To examine mortality in men with an infertility or infertility-related diagnosis.Design, setting, and participants: Population-based cohort study of men born in 1944-1992 in Sweden. We used Cox regression estimated hazard ratios (HRs) for infertility while adjusting for number of children, education, year of birth, country of birth, diabetes, hypertension, liver disease and end-stage renal disease. In all, 43,598 men with a diagnosis of infertility and 57,733 men with an infertility-related diagnosis were compared with 2,762,254 men (reference group) without such diagnoses.Outcome measures: All-cause and cause-specific mortality at age 20 to 69 years.Results and limitations: The 2,863,585 men in the study were followed for a median time of 22.0 years. During follow-up, 439 men with a diagnosis of infertility died, corresponding to a crude incidence rate of 1.56 deaths per 1,000 person-years. These figures can be compared with 1,400 deaths in men with an infertility-related diagnosis (1.96 deaths/1,000 person-years) and 99,463 deaths in reference individuals (2.17 deaths/1,000 person-years). Overall, men with a diagnosis of infertility did not have a higher risk of death (adjusted [a] HR=0.98; 95% confidence interval [95% CI]=0.89-1.08), but had a higher risk of death before age 30 (20-29 years) (aHR=3.26; 95% CI=2.42-4.41). This early excess mortality was largely explained by cancer diagnosed before infertility. Having an infertility-related diagnosis was associated with death (aHR=1.23; 95% CI=1.17-1.30). Limitations include the lack of general screening for infertility in Sweden and the lack of information on semen parameters.Conclusion: Men with a diagnosis of infertility are not at a higher risk of death than the general population, although having a diagnosis related to infertility may be linked to a higher risk of death.Patient summary: Men with a diagnosis of infertility do not seem to have a higher risk of death though an infertility-related diagnosis in men is associated with the risk of death.
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| 36. |
- Lundberg, Mari, 1969, et al.
(författare)
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Pain-related fear: a critical review of the related measures.
- 2011
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Ingår i: Pain research and treatment. - : Hindawi Limited. - 2090-1550 .- 2090-1542. ; 2011
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: In regards to pain-related fear, this study aimed to: (1) identify existing measures and review their measurement properties, and (2) identify the optimum measure for specific constructs of fear-avoidance, pain-related fear, fear of movement, and kinesiophobia. Design: Systematic literature search for instruments designed to measure fear of pain in patients with persistent musculoskeletal pain. Psychometric properties were evaluated by adjusted Wind criteria. Results: Five questionnaires (Fear-Avoidance Beliefs Questionnaire (FABQ), Fear-Avoidance of Pain Scale (FAPS), Fear of Pain Questionnaire (FPQ), Pain and Anxiety Symptoms Scale (PASS), and the Tampa Scale for Kinesiophobia (TSK)) were included in the review. The main findings were that for most questionnaires, there was no underlying conceptual model to support the questionnaire's construct. Psychometric properties were evaluated by diverse methods, which complicated comparisons of different versions of the same questionnaires. Construct validity and responsiveness was generally not supported and/or untested. Conclusion: The weak construct validity implies that no measure can currently identify who is fearful. The lack of evidence for responsiveness restricts the current use of the instruments to identify clinically relevant change from treatment. Finally, more theoretically driven research is needed to support the construct and thus the measurement of pain-related fear.
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| 37. |
- Rentzos, Georgios K., et al.
(författare)
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Use of a basophil activation test as a complementary diagnostic tool in the diagnosis of severe peanut allergy in adults
- 2015
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Ingår i: Clinical and Translational Allergy. - : Wiley. - 2045-7022. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- Background: Diagnosis of severe peanut allergy is difficult and delays in making an accurate diagnosis may place the patient at risk. Adults with a history of anaphylaxis must strictly avoid any contact with peanuts or products that may contain traces of peanuts. For these persons, conventional evaluations with skin prick testing (SPT) and IgE tests may not be sufficient to assess the risk of anaphylaxis. Therefore, we investigated whether the basophil activation test (BAT) could be used for the diagnosis of severe peanut allergy in adults. We compared the non-invasive BAT with conventional laboratory diagnostic tests, including SPT and specific IgE to allergen extracts and components, for the diagnosis of severe peanut allergy. Methods: Forty-seven persons with severe allergy to peanuts and a clinical diagnosis of anaphylaxis (PA-group), 22 subjects with peanut sensitization (PS-group) and 22 control (C-group) subjects, all in the age range of 18-60 years, were recruited retrospectively and prospectively into the study. Thirty-four patients with peanut allergy and 11 peanut-sensitized patients were sensitized to soy, while 36 patients in the PA-group and 20 patients in the PS-group were sensitized to birch pollen. All the patients and control subjects were investigated with BAT and SPT for responses to peanut, soy and birch extracts and their serum samples were assayed for the presence of specific IgE to peanut, soy and birch extracts, as well as IgE to allergen components (ISAC). Results: In a multivariate factor analysis, severe peanut allergy (PA) was positively associated with SPT to peanut, IgE to peanut, BAT to peanut and IgE to rAra h 1, 2, 3 and 6 peanut components, as well as to soy components (nGly m 5 and nGly m 6). In contrast, peanut sensitization was positively associated with increased levels of IgE to rAra h 8, birch and birch-related components. BAT-detected reactivity to peanut was significantly higher in patients who had a history of severe allergy to peanuts, as compared with patients who were sensitized to peanuts (p < 0.001), and the receiver operating curve (ROC) analysis showed that BAT had high sensitivity and specificity for predicting severe peanut allergy, with a ROC area under the curve of 0.862. However, in the PA-group, the BAT results for peanut correlated only weakly with the levels of IgE to rAra h 1, 2 and 3 and nAra h 6. Study limitations: oral provocation in the patients with a history of severe peanut allergy could not be performed to compare clinical reactivity with the BAT result due to ethical constraints. Neither was it possible to perform BAT with peanut recombinant allergens which were not available at the time the study commenced Conclusions: BAT is useful in determining the severity of peanut allergy and may be used as a complementary diagnostic tool to ensure accurate diagnosis of severe peanut allergy in adults. Thus, it may reduce the need to subject these patients to further tests, including an open challenge with peanuts. © 2015 Rentzos et al.; licensee BioMed Central.
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| 38. |
- Rodriguez-Wallberg, Kenny A., et al.
(författare)
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Mortality from infancy to adolescence in singleton children conceived from assisted reproductive techniques versus naturally conceived singletons in Sweden
- 2020
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Ingår i: Fertility and Sterility. - : Elsevier. - 0015-0282 .- 1556-5653. ; 113:3, s. 524-532
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To assess infant (<1 year) and childhood (1-18 years) mortality in singletons conceived through assisted reproductive techniques (ART) versus naturally conceived singletons.Design: Nationwide prospective study.Setting: Sweden.Patient(s): All singleton liveborn infants born from 1983 to 2012 in Sweden identified using the Medical Birth Register (N = 2,847,108), of whom 43,506 were conceived through ART treatments including in vitro fertilization with and without intracytoplasmic sperm injection.Intervention(s): None.Main Outcome Measures(s): Infant (<1 year) and childhood (1-18 years) mortality.Result(s): Data on ART treatment and covariates were retrieved from population-based registers using the unique personal identity number assigned to all permanent residents in Sweden. Cox proportional hazards models estimated the hazard ratios (HRs) with 95% confidence intervals (CIs) as measures of association between ART treatments and death. The analyses were adjusted for maternal characteristics, infertility, child sex, and birth cohort and were restricted to individuals with complete information on covariates for fully adjusted analysis. Compared with naturally conceived singletons, higher infant mortality risks were seen in infants conceived through ART (adjusted HR 1.45; 95% CI, 1.19-1.77), especially after transfer of cryopreserved embryos (adjusted HR 2.30; 95% CI, 1.46-3.64). Early neonatal mortality risk (deaths during the first week) was increased in children born after transfer of blastocysts (HR 2.40; 95% CI, 1.05-5.48). No increased mortality risk was observed between the ages of 1 and 18 years.Conclusion(s): Singletons conceived through ART had an increased risk of infant mortality from birth up to 1 year of life, predominantly in the early neonatal period and in pregnancies after transfer of frozen and thawed embryos. (C) 2019 by American Society for Reproductive Medicine.
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| 39. |
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| 40. |
- Vadeby, Anna, 1969-, et al.
(författare)
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Säker framkomlighet : spårutveckling på mitträfflade, mötesfria och riktningsseparerade vägar
- 2016
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Detta notat redovisar en studie av spårdjupstillväxt för tre olika åtgärder som implementerats inom Trafikverkets projekt ”Säker framkomlighet”. Åtgärderna är:2-fältsvägar med frästa mitträfflorsmala mötesfria vägar (”gles 2+1-väg med räcke”)riktningsseparerade vägar (2+1 med målad/räfflad mitt)Såväl mitträffling som mitträcke kan innebära att trafiken kanaliseras mer och därmed ge en snabbare tillväxttakt för spårbildning. Syftet med studien är att redovisa effekter på årlig spårtillväxt i första hand och i andra hand årlig tillväxt av spårarea för 2-fältsvägar med frästa mitträfflor, mötesfria vägar och riktningsseparerade vägar.Resultaten visar att för mitträffling finns ibland skillnader mellan spårtillväxten på test- och kontrollsträckorna men denna skillnad är oftast mycket liten och skillnaderna slår dessutom åt båda håll, vilket innebär att resultatet inte pekar konsekvent åt ena eller andra hållet. Slutsatsen av resultaten är att mitträffling inte ger en kanaliserande effekt på trafiken och därmed påverkas heller inte spårbildningen.
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| 41. |
- Wernersson, Erik, et al.
(författare)
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Deconwolf enables high-performance deconvolution of widefield fluorescence microscopy images
- 2024
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Ingår i: Nature Methods. - 1548-7091 .- 1548-7105.
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Tidskriftsartikel (refereegranskat)abstract
- Microscopy-based spatially resolved omic methods are transforming the life sciences. However, these methods rely on high numerical aperture objectives and cannot resolve crowded molecular targets, limiting the amount of extractable biological information. To overcome these limitations, here we develop Deconwolf, an open-source, user-friendly software for high-performance deconvolution of widefield fluorescence microscopy images, which efficiently runs on laptop computers. Deconwolf enables accurate quantification of crowded diffraction limited fluorescence dots in DNA and RNA fluorescence in situ hybridization images and allows robust detection of individual transcripts in tissue sections imaged with x20 air objectives. Deconvolution of in situ spatial transcriptomics images with Deconwolf increased the number of transcripts identified more than threefold, while the application of Deconwolf to images obtained by fluorescence in situ sequencing of barcoded Oligopaint probes drastically improved chromosome tracing. Deconwolf greatly facilitates the use of deconvolution in many bioimaging applications. Deconwolf is a computationally efficient and user-friendly software tool for fluorescence microscopy image deconvolution that improves the analysis of diverse fluorescence in situ hybridization methods and can handle large datasets.
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