↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Malietzis G) "

Search: WFRF:(Malietzis G)

Result 1-3 of 3

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Ortiz, M. L., et al. (author) Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4(+) T cells 2015 In: Journal of Experimental Medicine. - : Rockefeller University Press. - 0022-1007 .- 1540-9538. ; 212:3, s. 351-367 Journal article (peer-reviewed)abstract Evidence links chronic inflammation with cancer, but cellular mechanisms involved in this process remain unclear. We have demonstrated that in humans, inflammatory conditions that predispose to development of skin and colon tumors are associated with accumulation in tissues of CD33(+)S100A9(+) cells, the phenotype typical for myeloid-derived suppressor cells in cancer or immature myeloid cells (IMCs) in tumor-free hosts. To identify the direct role of these cells in tumor development, we used S100A9 transgenic mice to create the conditions for topical accumulation of these cells in the skin in the absence of infection or tissue damage. These mice demonstrated accumulation of granulocytic IMCs in the skin upon topical application of 12-O-tetradecanoylphorbol-13-acetate (TPA), resulting in a dramatic increase in the formation of papillomas during epidermal carcinogenesis. The effect of IMCs on tumorigenesis was not associated with immune suppression, but with CCL4 (chemokine [C-C motif] ligand 4)-mediated recruitment of IL-17-producing CD4(+) T cells. This chemokine was released by activated IMCs. Elimination of CD4(+) T cells or blockade of CCL4 or IL-17 abrogated the increase in tumor formation caused by myeloid cells. Thus, this study implicates accumulation of IMCs as an initial step in facilitation of tumor formation, followed by the recruitment of CD4(+) T cells.
2.	Srinivasaiah, N, et al. (author) Minimally invasive surgery techniques in pelvic exenteration: a systematic and meta-analysis review 2018 In: Surgical endoscopy. - : Springer Science and Business Media LLC. - 1432-2218 .- 0930-2794. ; 32:12, s. 4707-4715 Journal article (peer-reviewed)
3.	Gottlieb-Vedi, E, et al. (author) Long-term Survival in Esophageal Cancer After Minimally Invasive Compared to Open Esophagectomy: A Systematic Review and Meta-analysis 2019 In: Annals of surgery. - 1528-1140. ; 270:6, s. 1005-1017 Journal article (peer-reviewed)

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-3 of 3

Refine your search

Type of publication: journal article (3)

Type of content: peer-reviewed (3)

Author/Editor: Kim, H. (1); Aalbers, AGJ (1); Abraham-Nordling, M (1); Alberda, W (1); Antoniou, A (1); Austin, KK (1); show more...; Beets, GL (1); Berg, PL (1); Brunner, M (1); Burger, JWA (1); Campain, N (1); Chan, KKL (1); Christensen, HK (1); Colquhoun, AJ (1); Coscia, M (1); Davies, RJ (1); de Wilt, JHW (1); Deutsch, C (1); Dietz, D (1); Duff, M (1); Fearnhead, N (1); Garcia-Sabrido, JL (1); Gentilini, L (1); Heriot, AG (1); Hohenberger, W (1); Holm, T (1); Jenkins, JT (1); Kanemitsu, Y (1); Koh, CE (1); Kontovounisios, C (1); Law, WL (1); Laurberg, S (1); Lynch, AC (1); Martling, A (1); Merkel, S (1); McGrath, JS (1); Nielsen, MB (1); Nieuwenhuijzen, GAP (1); Nilsson, PJ (1); Patsouras, D (1); Poggioli, G (1); Radwan, RW (1); Rasheed, S (1); Rasmussen, PC (1); Rutten, HJT (1); Sagar, PM (1); Schizas, AMP (1); Shida, D (1); Solomon, MJ (1); Sorensen, MM (1); show less...

University: Karolinska Institutet (2); University of Gothenburg (1)

Language: English (3)

Research subject (UKÄ/SCB): Medical and Health Sciences (2)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view