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- Thornton, LM, et al.
(author)
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A Comparison of Personality, Life Events, Comorbidity, and Health in Monozygotic Twins Discordant for Anorexia Nervosa
- 2017
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In: Twin research and human genetics : the official journal of the International Society for Twin Studies. - : Cambridge University Press (CUP). - 1832-4274. ; 20:4, s. 310-318
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Journal article (peer-reviewed)abstract
- Genetic and environmental factors contribute to the etiology of anorexia nervosa (AN). The co-twin control design is one of the most powerful methods available to evaluate environmental factors that could contribute to differences between monozygotic (MZ) twins who are discordant for AN. Using available data from a unique and rare sample of 22 Swedish female MZ pairs discordant for AN, we compared personality, life events, comorbidity, and health factors. Twins with AN had significantly higher perfectionism scores than unaffected co-twins and reported younger ages at first diet than unaffected co-twins who had dieted. Consistent with previous literature, more twins with AN reported gastrointestinal problems than unaffected co-twins. Although not significant due to low statistical power, more unaffected co-twins reported experiencing emotional neglect than twins with AN. Early dieting may be a harbinger of the development of AN or an early symptom. Higher perfectionism may represent a risk factor, sequela, or both. Sibling perception of neglect is noteworthy given the impact of an ill child with AN on family function and wellbeing. The health and wellbeing of siblings should be addressed clinically when one child in the family suffers from AN.
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- Mitchell, KS, et al.
(author)
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An investigation of a measure of twins' equal environments
- 2007
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In: Twin research and human genetics : the official journal of the International Society for Twin Studies. - : Cambridge University Press (CUP). - 1832-4274. ; 10:6, s. 840-847
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Journal article (peer-reviewed)abstract
- The equal environments assumption, which holds that trait-relevant environments are equally correlated among monozygotic (MZ) and dizygotic (DZ) twin pairs, is essential to twin designs. Violations of this assumption could lead to biased parameter estimates in twin models. A variety of methods and measures have been used to test this assumption. No studies to date have evaluated the measurement invariance of such items or examined the distribution of the underlying equal environments trait. The current study was an investigation of the psychometric properties of a self-report measure of twins' equal environments. Exploratory and confirmatory factor analysis results indicated that items loaded onto ‘child’ and ‘teen’ equal environments factors. Factor loadings and factor variances and their covariance were invariant for MZ and DZ twins; however, DZ twins had significantly lower factor means than MZ twins. Further, these items demonstrated adequate test–retest reliability. Lastly, the child and teen factors may be bimodally distributed, particularly for MZ twin pairs. Measurement invariance issues, as well as distributions of equal environments traits, should be considered when evaluating the equal environments assumption, in order to produce accurate parameter estimates in twin models.
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