| 1. |
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| 2. |
- Mishra, A, et al.
(author)
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Diminishing benefits of urban living for children and adolescents' growth and development
- 2023
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In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 615:7954, s. 874-883
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Journal article (peer-reviewed)abstract
- Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million participants, to report the height and body-mass index (BMI) of children and adolescents aged 5–19 years on the basis of rural and urban place of residence in 200 countries and territories from 1990 to 2020. In 1990, children and adolescents residing in cities were taller than their rural counterparts in all but a few high-income countries. By 2020, the urban height advantage became smaller in most countries, and in many high-income western countries it reversed into a small urban-based disadvantage. The exception was for boys in most countries in sub-Saharan Africa and in some countries in Oceania, south Asia and the region of central Asia, Middle East and north Africa. In these countries, successive cohorts of boys from rural places either did not gain height or possibly became shorter, and hence fell further behind their urban peers. The difference between the age-standardized mean BMI of children in urban and rural areas was <1.1 kg m–2 in the vast majority of countries. Within this small range, BMI increased slightly more in cities than in rural areas, except in south Asia, sub-Saharan Africa and some countries in central and eastern Europe. Our results show that in much of the world, the growth and developmental advantages of living in cities have diminished in the twenty-first century, whereas in much of sub-Saharan Africa they have amplified.
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| 3. |
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| 4. |
- Lind, Lars, et al.
(author)
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Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC)
- 2021
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In: eLife. - : eLife Sciences Publications Ltd. - 2050-084X. ; 10
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Journal article (peer-reviewed)abstract
- From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions.
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| 5. |
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| 6. |
- Bentham, James, et al.
(author)
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A century of trends in adult human height
- 2016
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In: eLIFE. - 2050-084X. ; 5
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Journal article (peer-reviewed)abstract
- Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.522.7) and 16.5 cm (13.319.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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| 7. |
- Bentham, James, et al.
(author)
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A century of trends in adult human height
- 2016
-
In: eLIFE. - : eLife Sciences Publications Ltd. - 2050-084X. ; 5
-
Journal article (peer-reviewed)abstract
- Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5–22.7) and 16.5 cm (13.3– 19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8– 144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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| 8. |
- Bui, Ha Thi Thu, et al.
(author)
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The Association Between Gender Inequalities and Women's Utilization of Maternal Health Services : A Cross-Sectional Survey in Eight South Central Coast Provinces, Vietnam
- 2018
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In: Journal of Public Health Management and Practice. - 1078-4659 .- 1550-5022. ; 24:2, s. S19-S27
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Journal article (peer-reviewed)abstract
- Background: Gender inequalities influence the utilization of maternal health services in Vietnam, but little research has been published. This study, therefore, aimed to explore the association between gender inequalities and women's utilization of maternal health services in Vietnam.Methods: The study was conducted in 8 provinces in the South Central Coast region of Vietnam during August 2013 to May 2014. A total of 907 women who delivered a year prior to the date of interview participated in the study. A multiple logistic regression model was used to examine the association between gender inequalities (including sociodemographic determinants of health) and utilization of 4 or more antenatal care (ANC4+) services, institutional delivery, and ever used contraceptive methods.Results: The utilization rate of maternal health services was varied, from 53.9% for ANC4+ to 87.7% for ever used a contraceptive method and 97% for institutional delivery. Ethnicity was identified as the most influential variable out of all sociodemographic determinants of health. Regarding gender inequalities, couple communication was the only variable having significant association with women's utilization of maternal health services.Conclusion: Women's equal role within context of their daily life and relations with their husbands (discussing maternal care with husband and having equal income to husband) supported their use of maternal health services. Therefore, there should be concerted efforts from all relevant stakeholders including the health system to focus on disadvantaged women in planning and delivery of maternal health services, especially to ethnic minority women. Male involvement strategy should be implemented to promote maternal health care, especially during the prenatal and postpartum period. To provide more culturally sensitive and right-based approaches in delivery of maternal health services to disadvantaged women in Vietnam, interventions are recommended that promote male involvement, that is, to engage men in service delivery to adapt and ensure the most appropriate and effective maternal health care.
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| 9. |
- Chu, Dinh-Toi, et al.
(author)
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An update on obesity : Mental consequences and psychological interventions
- 2019
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In: Diabetes & Metabolic syndrome. - : Elsevier. - 1871-4021 .- 1878-0334. ; 13:1, s. 155-160
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Research review (peer-reviewed)abstract
- Besides physical consequences, obesity has negative psychological effects, thereby lowering human life quality. Major psychological consequences of this disorder includes depression, impaired body image, low self-esteem, eating disorders, stress and poor quality of life, which are correlated with age and gender. Physical interventions, mainly diet control and energy balance, have been widely applied to treat obesity; and some psychological interventions including behavioral therapy, cognitive behavioral therapy and hypnotherapy have showed some effects on obesity treatment. Other psychological therapies, such as relaxation and psychodynamic therapies, are paid less attention. This review aims to update scientific evidence regarding the mental consequences and psychological interventions for obesity. (c) 2018 Diabetes India. Published by Elsevier Ltd. All rights reserved.
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| 10. |
- Chuong, Nguyen Canh, et al.
(author)
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Amniocentesis test uptake for congenital defects : Decision of pregnant women in Vietnam
- 2018
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In: Health Care for Women International. - : TAYLOR & FRANCIS INC. - 0739-9332 .- 1096-4665. ; 39:4, s. 493-504
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Journal article (peer-reviewed)abstract
- Our study aimed to identify the knowledge, attitude, and factors associated with uptake of amniocentesis test amongst pregnant women of advanced maternal age (35+ years old). A cross-sectional survey was performed on 481 participants in 2016. Women with higher educational attainment, higher income level, having a baby with congenital defects, and women with better knowledge and/or attitude about amniocentesis test were more likely to accept the test. Our study suggested the importance of counseling for women and more time should be given for them to absorb information before they make their decision to uptake the amniocentesis test.
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| 11. |
- Dao, Trong Tuan, et al.
(author)
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Resveratrol suppressed lps-induced cox-2 VIA miR-146a-5p inhibition in raw246.7 cells
- 2017
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In: Farmacia. - 0014-8237. ; 65:2, s. 214-218
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Journal article (peer-reviewed)abstract
- Trans-resveratrol (Res) is a well-known natural stilbene frequently found in grapes which have been reported to possess antioxidant, anti-cancer activities and inhibited COX-2 expression. MicroRNAs (miRNAs) are short endogenous non-coding RNAs involved in the regulation of mRNA stability and protein synthesis. In our research, resveratrol isolated from Vitis heyneana Roem. & Schult Vitis heyneana was observed to suppress lipopolysaccharides (LPS)-induced COX-2 expression in Raw264.7 cells in a dose dependent manner. Using qPCR it was revealed that LPS induced the expression of miR-25, miR- 125a, miR-125b, miR-146a-5p, miR-146a-3p and miR-455. However, we only observed miR-146a-5p expression significantly decreased in resveratrol compared to untreated-control group. In addition, resveratrol abrogated the effect of miR-146a-5p mimic induced-COX-2 expression in Raw264.7 cells. Taken together, this study demonstrated for the first time the involvement of miR-146a-5p in resveratrol inhibited LPS-induced COX-2 expression in Raw264.7 cells.
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| 12. |
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| 13. |
- Duyen, Nguyen Thi, et al.
(author)
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Steroid glycosides isolated from Paris polyphylla var. chinensis aerial parts and paris saponin II induces G1/S-phase MCF-7 cell cycle arrest
- 2022
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In: Carbohydrate Research. - : Elsevier BV. - 0008-6215. ; 519
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Journal article (peer-reviewed)abstract
- In our previous research on Vietnamese medicinal plants, we found that the ethanolic extract of the aerial parts of Paris polyphylla var. chinensis exhibited cytotoxic effects in vitro in the MCF-7 human cancer cell line. Here, we used combined chromatographic separations to isolate six compounds including a new steroid glycoside, paripoloside A (3), and five known compounds, from the butanol extract of the aerial parts of P. polyphylla. We unambiguously elucidated their structures based on spectroscopic data (proton and carbon-13 nuclear magnetic resonance, heteronuclear single quantum coherence, heteronuclear multiple bond correlation, correlation spectroscopy, and high-resolution electrospray ionization mass spectroscopy data), and chemical reactions. Among the isolated compounds, paris saponin II (PSII) had the strongest cytotoxic effects against MCF-7 breast cancer cells. Interestingly, PSII significantly increased the expression of p53, p21, p27, and Bax protein levels and significantly suppressed the expression of cyclin D1 and retinoblastoma protein. These data suggest that PSII may induce G1/S phase cell cycle arrest and apoptosis pathway development in MCF-7 cells. Furthermore, the MCF-7 breast cancer cells mechanism of PSII was also investigated using molecular docking. Together, our results demonstrate that isolated compounds from P. polyphylla are promising candidates as breast cancer inhibitors.
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| 14. |
- Le, Vui Thi, et al.
(author)
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Sex Ratio at Birth in Vietnam : Results From Data in CHILILAB HDSS, 2004 to 2013
- 2017
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In: Asia-Pacific journal of public health. - : SAGE PUBLICATIONS INC. - 1010-5395 .- 1941-2479. ; 29:5 Suppl., s. 25S-34S
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Journal article (peer-reviewed)abstract
- This study aimed to explore the association of demographic and socioeconomic characteristics and imbalanced sex ratio at birth (SRB) in Chi Linh district, Hai Duong. The data were collected from a longitudinal study using a community-based periodic, referred as Chi Linh Health and Demographic Surveillance System (CHILILAB HDSS) during 2004 to 2013. A total of 7568 children were analyzed. Results showed that SRB in Chi Linh dramatically increased to the imbalanced sex ratio (114.6 boys to 100 girls) by 2013. SRB was associated with birth order and sex of preceding siblings. SRB was extremely high among families without any sons (136/100). SRB was highest among families having third or more children (175/100). Imbalanced SRB was more likely to occur among women working in small business/homemakers and others, women who attained high education level, and women in wealthy households. We suggested further efforts to tackle imbalanced SRB in periurban areas in Vietnam.
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| 15. |
- Taddei, C, et al.
(author)
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Repositioning of the global epicentre of non-optimal cholesterol
- 2020
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In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 582:7810, s. 73-
-
Journal article (peer-reviewed)abstract
- High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol—which is a marker of cardiovascular risk—changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million–4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world.
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| 16. |
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| 17. |
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| 18. |
- Bertmar, Sofia, et al.
(author)
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Who's Most Targeted and Does My New Adblocker Really Help : A Profile-based Evaluation of Personalized Advertising
- 2021
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In: Proc. ACM CCS Workshop on Privacy in the Electronic Society (ACM WPES @CCS). - New York, NY, USA : ACM Digital Library. - 9781450385275
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Conference paper (peer-reviewed)abstract
- There is limited prior work studying how the ad personalization experienced by different users is impacted by the use of adblockers, geographic location, the user's persona, or what browser they use. To address this void, this paper presents a novel profile-based evaluation of the personalization experienced by carefully crafted user profiles. Our evaluation framework impersonates different users and captures how the personalization changes over time, how it changes when adding or removing an extension, and perhaps most importantly how the results differ depending on the profile's persona (e.g., interest, occupation, age, gender), geographic location (US East, US West, UK), what browser extension they use (none, AdBlock, AdBlock Plus, Ghostery, CatBlock), what browser they use (Chrome, Firefox), and whether they are logged in to their Google account. By comparing and contrasting observed differences we provide insights that help explain why some user groups may feel more targeted than others and why some people may feel even more targeted after having turned on their adblocker.
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| 19. |
- Giang, Kim Bao, et al.
(author)
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Relative Importance of Different Attributes of Graphic Health Warnings on Tobacco Packages in Viet Nam
- 2016
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In: Asian Pacific Journal of Cancer Prevention. - 1513-7368. ; 17, s. 79-84
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Journal article (peer-reviewed)abstract
- Graphic health warnings (GHW) on tobacco packages have proven to be effective in increasing quit attempts among smokers and reducing initial smoking among adolescents. This research aimed to examine the relative importance of different attributes of graphic health warnings on tobacco packages in Viet Nam. A discrete choice experimental (DCE) design was applied with a conditional logit model. In addition, a ranking method was used to list from the least to the most dreadful GHW labels. With the results from DCE model, graphic type was shown to be the most important attribute, followed by cost and coverage area of GHW. The least important attribute was position of the GHW. Among 5 graphic types (internal lung cancer image, external damaged teeth, abstract image, human suffering image and text), the image of lung cancer was found to have the strongest influence on both smokers and non-smokers. With ranking method, the image of throat cancer and heart diseases were considered the most dreadful images. GHWs should be designed with these attributes in mind, to maximise influence on purchase among both smokers and non-smokers.
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| 20. |
- Hwang, Seong Oun, et al.
(author)
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Efficient certificate-based encryption and hierarchical certificate-based encryption schemes in the standard model
- 2018
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In: Journal of Intelligent & Fuzzy Systems. - : IOS Press. - 1064-1246 .- 1875-8967. ; 35:6, s. 5971-5981
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Journal article (peer-reviewed)abstract
- Telco systems usually run large-scale, centralized key management systems. However, centralized approaches based on conventional public key encryption like RSA raise problems such as key escrow, secure channel to delivery key, and third-party query as well as single point of failure. To address these problems, we propose both certificate-based encryption (CBE) and hierarchical certificate-based encryption (HCBE) schemes proved secure in the standard model. Compared with other schemes, our schemes are proved IND-CCA2 (Indistinguishability under Adaptive Chosen Ciphertext Attack) secure in full model, where the number of group elements is independent of the value of security parameter. As far as we know, the proposed HCBE is the first fully IND-CCA2 secure scheme with ciphetexts of constant size.
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| 21. |
- Le, Minh Ha, et al.
(author)
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AnonFACES: Anonymizing Faces Adjusted to Constraints on Efficacy and Security
- 2020
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In: WPES 2020 - Proceedings of the 19th Workshop on Privacy in the Electronic Society. - New York, NY, USA : ACM. ; , s. 87-100, s. 87-100
-
Conference paper (peer-reviewed)abstract
- Image data analysis techniques such as facial recognition can threaten individuals’ privacy. Whereas privacy risks often can be reduced by adding noise to the data, this approach reduces the utility of the images. For this reason, image de-identification techniques typically replace directly identifying features (e.g., faces, car number plates) present in the data with synthesized features, while still preserving other non-identifying features. As of today, existing techniques mostly focus on improving the naturalness of the generated synthesized images, without quantifying their impact on privacy. In this paper, we propose the first methodology and system design to quantify, improve, and tune the privacy-utility trade-off, while simultaneously also improving the naturalness of the generated images. The system design is broken down into three components that address separate but complementing challenges. This includes a two-step cluster analysis component to extract low-dimensional feature vectors representing the images (embedding) and to cluster the images into fixed-sized clusters. While the importance of good clustering mostly has been neglected in previous work, we find that our novel approach of using low-dimensional feature vectors can improve the privacy-utility trade-off by better clustering similar images. The use of these embeddings has been found particularly useful when wanting to ensure high naturalness and utility of the synthetically generated images. By combining improved clustering and incorporating StyleGAN, a state-of-the-art Generative Neural Network, into our solution, we produce more realistic synthesized faces than prior works, while also better preserving properties such as age, gender, skin tone, or even emotional expressions. Finally, our iterative tuning method exploits non-linear relations between privacy and utility to identify good privacy-utility trade-offs. We note that an example benefit of these improvements is that our solution allows car manufacturers to train their autonomous vehicles while complying with privacy laws.
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| 22. |
- Le, Minh-Ha, et al.
(author)
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Certificate-Based Signcryption Scheme without Pairing : Directly Verifying Signcrypted Messages Using a Public Key
- 2016
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In: ETRI Journal. - : John Wiley & Sons. - 1225-6463 .- 2233-7326. ; 38:4, s. 724-734
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Journal article (peer-reviewed)abstract
- To achieve confidentiality, integrity, authentication, and non-repudiation simultaneously, the concept of signcryption was introduced by combining encryption and a signature in a single scheme. Certificate-based encryption schemes are designed to resolve the key escrow problem of identity-based encryption, as well as to simplify the certificate management problem in traditional public key cryptosystems. In this paper, we propose a new certificate-based signcryption scheme that has been proved to be secure against adaptive chosen ciphertext attacks and existentially unforgeable against chosen-message attacks in the random oracle model. Our scheme is not based on pairing and thus is efficient and practical. Furthermore, it allows a signcrypted message to be immediately verified by the public key of the sender. This means that verification and decryption of the signcrypted message are decoupled. To the best of our knowledge, this is the first signcryption scheme without pairing to have this feature.
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| 23. |
- Le, Minh-Ha, et al.
(author)
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Efficient certificate-based encryption schemes without pairing
- 2016
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In: Security and Communication Networks. - : John Wiley & Sons. - 1939-0114 .- 1939-0122. ; 9:18, s. 5376-5391
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Journal article (peer-reviewed)abstract
- Recently, a lot of researches focused on identity-based encryption (IBE). The advantage of this scheme is that it can reduce the cost of the public key infrastructure by simplifying certificate management. Although IBE has its own innovations, one of its weaknesses is the key escrow problem. That is, the private key generator in IBE knows decryption keys for all identities and consequently can decrypt any ciphertexts. The certificate-based encryption (CBE) scheme proposed in EUROCRYPT 2003 provides a solution for the key escrow problem by allowing the certification authority to possess a partial decryption key that comprises the full decryption key together with the user-generated private key. In this paper, we propose new CBE schemes without pairing and prove them to be Indistinguishability under Chosen Ciphertext Attack secure in the random oracle model based on the hardness of the computational Diffie-Hellman problem. When compared with other CBE schemes, our schemes are significantly efficient in terms of performance, which makes our schemes suitable for computation-limited node (e.g., sensor, wearable device) networks. Copyright (c) 2016 John Wiley & Sons, Ltd.
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| 24. |
- Le, Minh Ha, et al.
(author)
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IdDecoder: A Face Embedding Inversion Tool and its Privacy and Security Implications on Facial Recognition Systems
- 2023
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In: Proceedings of the Thirteenth ACM Conference on Data and Application Security and Privacy. - : ACM Digital Library. - 9798400700675 ; , s. 15-26
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Conference paper (peer-reviewed)abstract
- Most state-of-the-art facial recognition systems (FRS:s) use face embeddings. In this paper, we present the IdDecoder framework, capable of effectively synthesizing realistic-neutralized face images from face embeddings, and two effective attacks on state-of-the-art facial recognition models using embeddings. The first attack is a black-box version of a model inversion attack that allows the attacker to reconstruct a realistic face image that is both visually and numerically (as determined by the FRS:s) recognized as the same identity as the original face used to create a given face embedding. This attack raises significant privacy concerns regarding the membership of the gallery dataset of these systems and highlights the importance of both the people designing and deploying FRS:s paying greater attention to the protection of the face embeddings than currently done. The second attack is a novel attack that performs the model inversion, so to instead create the face of an alternative identity that is visually different from the original identity but has close identity distance (ensuring that it is recognized as being of the same identity). This attack increases the attacked system's false acceptance rate and raises significant security concerns. Finally, we use IdDecoder to visualize, evaluate, and provide insights into differences between three state-of-the-art facial embedding models.
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| 25. |
- Le, Minh Ha, et al.
(author)
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StyleID: Identity Disentanglement for Anonymizing Faces
- 2023
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In: Proceedings on Privacy Enhancing Technologies (PoPETs).
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Journal article (peer-reviewed)abstract
- Privacy of machine learning models is one of the remaining challenges that hinder the broad adoption of Artificial Intelligent (AI). This paper considers this problem in the context of image datasets containing faces. Anonymization of such datasets is becoming increasingly important due to their central role in the training of autonomous cars, for example, and the vast amount of data generated by surveillance systems. While most prior work de-identifies facial images by modifying identity features in pixel space, we instead project the image onto the latent space of a Generative Adversarial Network (GAN) model, find the features that provide the biggest identity disentanglement, and then manipulate these features in latent space, pixel space, or both. The main contribution of the paper is the design of a feature-preserving anonymization framework, StyleID, which protects the individuals’ identity, while preserving as many characteristics of the original faces in the image dataset as possible. As part of the contribution, we present a novel disentanglement metric, three complementing disentanglement methods, and new insights into identity disentanglement. StyleID provides tunable privacy, has low computational complexity, and is shown to outperform current state-of-the-art solutions.
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| 26. |
- Le, Phong Q., et al.
(author)
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Iodine-promoted amide formation via oxidative cleavage of indoles : novel quinazoline-4(3H)-one and tryptanthrin syntheses
- 2024
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In: RSC Advances. - : Royal Society of Chemistry. - 2046-2069. ; 14:22, s. 15597-15603
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Journal article (peer-reviewed)abstract
- A highly efficient method for the direct construction of amide bonds via a selective cleavage of C-H and C=C bonds in indole structures using an iodine-promoted approach was developed. Mechanistic studies indicated the formation of superoxide radicals obtained from molecular oxygen activation as a key intermediate step, which provided a precursor for subsequent oxidative ring-opening and intermolecular cyclization. A broad range of quinazolin-4(3H)-ones and tryptanthrins were synthesized in moderate to good yields under mild and environmentally benign conditions.
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| 27. |
- Minh-Ha, Le, 1989-
(author)
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Beyond Recognition : Privacy Protections in a Surveilled World
- 2024
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Doctoral thesis (other academic/artistic)abstract
- This thesis addresses the need to balance the use of facial recognition systems with the need to protect personal privacy in machine learning and biometric identification. As advances in deep learning accelerate their evolution, facial recognition systems enhance security capabilities, but also risk invading personal privacy. Our research identifies and addresses critical vulnerabilities inherent in facial recognition systems, and proposes innovative privacy-enhancing technologies that anonymize facial data while maintaining its utility for legitimate applications.Our investigation centers on the development of methodologies and frameworks that achieve k-anonymity in facial datasets; leverage identity disentanglement to facilitate anonymization; exploit the vulnerabilities of facial recognition systems to underscore their limitations; and implement practical defenses against unauthorized recognition systems. We introduce novel contributions such as AnonFACES, StyleID, IdDecoder, StyleAdv, and DiffPrivate, each designed to protect facial privacy through advanced adversarial machine learning techniques and generative models. These solutions not only demonstrate the feasibility of protecting facial privacy in an increasingly surveilled world, but also highlight the ongoing need for robust countermeasures against the ever-evolving capabilities of facial recognition technology.Continuous innovation in privacy-enhancing technologies is required to safeguard individuals from the pervasive reach of digital surveillance and protect their fundamental right to privacy. By providing open-source, publicly available tools, and frameworks, this thesis contributes to the collective effort to ensure that advancements in facial recognition serve the public good without compromising individual rights. Our multi-disciplinary approach bridges the gap between biometric systems, adversarial machine learning, and generative modeling to pave the way for future research in the domain and support AI innovation where technological advancement and privacy are balanced.
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| 28. |
- Minh-Ha, Le, 1989-, et al.
(author)
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StyleAdv: A Usable Privacy Framework Against Facial Recognition with Adversarial Image Editing
- 2024
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In: Proceedings on Privacy Enhancing Technologies. ; , s. 106-123
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Conference paper (peer-reviewed)abstract
- In this era of ubiquitous surveillance and online presence, protecting facial privacy has become a critical concern for individuals and society as a whole. Adversarial attacks have emerged as a promising solution to this problem, but current methods are limited in quality or are impractical for sensitive domains such as facial editing. This paper presents a novel adversarial image editing framework called StyleAdv, which leverages StyleGAN's latent spaces to generate powerful adversarial images, providing an effective tool against facial recognition systems. StyleAdv achieves high success rates by employing meaningful facial editing with StyleGAN while maintaining image quality, addressing a challenge faced by existing methods. To do so, the comprehensive framework integrates semantic editing, adversarial attacks, and face recognition systems, providing a cohesive and robust tool for privacy protection. We also introduce the ``residual attack`` strategy, using residual information to enhance attack success rates. Our evaluation offers insights into effective editing, discussing tradeoffs in latent spaces, optimal edits for our optimizer, and the impact of utilizing residual information. Our approach is transferable to state-of-the-art facial recognition systems, making it a versatile tool for privacy protection. In addition, we provide a user-friendly interface with multiple editing options to help users create effective adversarial images. Extensive experiments are used to provide insights and demonstrate that StyleAdv outperforms state-of-the-art methods in terms of both attack success rate and image quality. By providing a versatile tool for generating high-quality adversarial samples, StyleAdv can be used both to enhance individual users' privacy and to stimulate advances in adversarial attack and defense research.
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| 29. |
- Tran, Hang Thi Thanh, et al.
(author)
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Therapeutic hypothermia after perinatal asphyxia in Vietnam : medium-term outcomes at 18 months - a prospective cohort study
- 2024
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In: BMJ Paediatrics Open. - : BMJ Publishing Group Ltd. - 2399-9772. ; 8:1
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Journal article (peer-reviewed)abstract
- Aim To determine neurodevelopmental outcome at 18 months after therapeutic hypothermia for hypoxic-ischaemic encephalopathy (HIE) infants in Vietnam, a low-middle-income country. Method Prospective cohort study investigating outcomes at 18 months in severely asphyxiated outborn infants who underwent therapeutic hypothermia for HIE in Hanoi, Vietnam, during the time period 2016-2019. Survivors were examined at discharge and at 6 and 18 months by a neonatologist, a neurologist and a rehabilitation physician, who were blinded to the infants' clinical severity during hospitalisation using two assessment tools: the Ages and Stages Questionnaire (ASQ) and the Hammersmith Infant Neurological Examination (HINE), to detect impairments and promote early interventions for those who require it. Results In total, 130 neonates, 85 (65%) with moderate and 45 (35%) with severe HIE, underwent therapeutic hypothermia treatment using phase change material. Forty-three infants (33%) died during hospitalisation and in infancy. Among the 87 survivors, 69 (79%) completed follow-up until 18 months. Nineteen children developed cerebral palsy (8 diplegia, 3 hemiplegia, 8 dyskinetic), and 11 had delayed neurodevelopment. At each time point, infants with a normal or delayed neurodevelopment had significantly higher ASQ and HINE scores (p<0.05) than those with cerebral palsy. Conclusion The rates of mortality and adverse neurodevelopment rate were high and comparable to recently published data from other low-middle-income settings. The ASQ and HINE were useful tools for screening and evaluation of neurodevelopment and neurological function.
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