1. |
- Kanai, M, et al.
(author)
-
- 2023
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swepub:Mat__t
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2. |
- Niemi, MEK, et al.
(author)
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- 2021
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swepub:Mat__t
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4. |
- Lind, Lars, et al.
(author)
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Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC)
- 2021
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In: eLife. - : eLife Sciences Publications Ltd. - 2050-084X. ; 10
-
Journal article (peer-reviewed)abstract
- From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions.
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6. |
- Bixby, H., et al.
(author)
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Rising rural body-mass index is the main driver of the global obesity epidemic in adults
- 2019
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In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 569:7755, s. 260-4
-
Journal article (peer-reviewed)abstract
- Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities(.)(1,2) This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity(3-6). Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017-and more than 80% in some low- and middle-income regions-was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing-and in some countries reversal-of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.
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7. |
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8. |
- Mishra, A, et al.
(author)
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Diminishing benefits of urban living for children and adolescents' growth and development
- 2023
-
In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 615:7954, s. 874-883
-
Journal article (peer-reviewed)abstract
- Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million participants, to report the height and body-mass index (BMI) of children and adolescents aged 5–19 years on the basis of rural and urban place of residence in 200 countries and territories from 1990 to 2020. In 1990, children and adolescents residing in cities were taller than their rural counterparts in all but a few high-income countries. By 2020, the urban height advantage became smaller in most countries, and in many high-income western countries it reversed into a small urban-based disadvantage. The exception was for boys in most countries in sub-Saharan Africa and in some countries in Oceania, south Asia and the region of central Asia, Middle East and north Africa. In these countries, successive cohorts of boys from rural places either did not gain height or possibly became shorter, and hence fell further behind their urban peers. The difference between the age-standardized mean BMI of children in urban and rural areas was <1.1 kg m–2 in the vast majority of countries. Within this small range, BMI increased slightly more in cities than in rural areas, except in south Asia, sub-Saharan Africa and some countries in central and eastern Europe. Our results show that in much of the world, the growth and developmental advantages of living in cities have diminished in the twenty-first century, whereas in much of sub-Saharan Africa they have amplified.
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24. |
- Adler, S. S., et al.
(author)
-
High transverse momentum eta meson production in p+p, d+Au, and Au+Au collisions at root s(NN)=200 GeV
- 2007
-
In: Physical Review C (Nuclear Physics). - 0556-2813. ; 75:2
-
Research review (peer-reviewed)abstract
- Inclusive transverse momentum spectra of eta mesons in the range p(T)approximate to 2-12 GeV/c have been measured at midrapidity (vertical bar eta vertical bar < 0.35) by the PHENIX experiment at RHIC in p+p,d+Au, and Au+Au collisions at root s(NN)=200 GeV. The eta mesons are reconstructed through their eta ->gamma gamma channel for the three colliding systems as well as through the eta ->pi(0)pi(+)pi(-) decay mode in p+p and d+Au collisions. The nuclear modification factor in d+Au collisions, R-dAu(p(T))approximate to 1.0-1.1, suggests at most only modest p(T) broadening ("Cronin enhancement"). In central Au+Au reactions, the eta yields are significantly suppressed, with R-AuAu(p(T))approximate to 0.2. The ratio of eta to pi(0) yields is approximately constant as a function of p(T) for the three colliding systems in agreement with the high-p(T) world average of R-eta/pi(0)approximate to 0.5 in hadron-hadron, hadron-nucleus, and nucleus-nucleus collisions for a wide range of center-of-mass energies (root sNN approximate to 3-1800 GeV) as well as, for high scaled momentum x(p), in e(+)e(-) annihilations at root s=91.2 GeV. These results are consistent with a scenario where high-p(T) eta production in nuclear collisions at the Relativistic Heavy Ion Collider is largely unaffected by initial-state effects but where light-quark mesons (pi(0),eta) are equally suppressed due to final-state interactions of the parent partons in the dense medium produced in Au+Au reactions.
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25. |
- Adler, S. S., et al.
(author)
-
Detailed study of high-p(T) neutral pion suppression and azimuthal anisotropy in Au plus Au collisions at root s(NN) =200 GeV
- 2007
-
In: Physical Review C (Nuclear Physics). - 0556-2813. ; 76:3
-
Journal article (peer-reviewed)abstract
- Measurements of neutral pion (pi(0)) production at midrapidity in root s(NN)=200 GeV Au+Au collisions as a function of transverse momentum, p(T), collision centrality, and angle with respect to reaction plane are presented. The data represent the final pi(0) results from the PHENIX experiment for the first RHIC Au+Au run at design center-of-mass energy. They include additional data obtained using the PHENIX Level-2 trigger with more than a factor of 3 increase in statistics over previously published results for p(T)>6 GeV/c. We evaluate the suppression in the yield of high-p(T) pi(0)'s relative to pointlike scaling expectations using the nuclear modification factor R-AA. We present the p(T) dependence of R-AA for nine bins in collision centrality. We separately integrate R-AA over larger p(T) bins to show more precisely the centrality dependence of the high-p(T) suppression. We then evaluate the dependence of the high-p(T) suppression on the emission angle Delta phi of the pions with respect to event reaction plane for seven bins in collision centrality. We show that the yields of high-p(T) pi(0)'s vary strongly with Delta phi, consistent with prior measurements 1,2. We show that this variation persists in the most peripheral bin accessible in this analysis. For the peripheral bins we observe no suppression for neutral pions produced aligned with the reaction plane, whereas the yield of pi(0)'s produced perpendicular to the reaction plane is suppressed by a factor of similar to 2. We analyze the combined centrality and Delta phi dependence of the pi(0) suppression in different p(T) bins using different possible descriptions of parton energy loss dependence on jet path-length averages to determine whether a single geometric picture can explain the observed suppression pattern.
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26. |
- Adler, S. S., et al.
(author)
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Evidence for a long-range component in the pion emission source in Au plus Au collisions at root s(NN)=200 GeV
- 2007
-
In: Physical Review Letters. - 1079-7114. ; 98:13
-
Journal article (peer-reviewed)abstract
- Emission source functions are extracted from correlation functions constructed from charged pions produced at midrapidity in Au+Au collisions at s(NN)=200 GeV. The source parameters extracted from these functions at low k(T) give first indications of a long tail for the pion emission source. The source extension cannot be explained solely by simple kinematic considerations. The possible role of a halo of secondary pions from resonance emissions is explored.
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27. |
- Adler, S. S., et al.
(author)
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Measurement of single muons at forward rapidity in p+p collisions at root s=200 GeV and implications for charm production
- 2007
-
In: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 1550-2368. ; 76:9
-
Journal article (peer-reviewed)abstract
- Muon production at forward rapidity (1.5 <=|eta|<= 1.8) has been measured by the PHENIX experiment over the transverse momentum range 1 <= p(T)<= 3 GeV/c in root s=200 GeV p+p collisions at the Relativistic Heavy Ion Collider. After statistically subtracting contributions from light hadron decays an excess remains which is attributed to the semileptonic decays of hadrons carrying heavy flavor, i.e. charm quarks or, at high p(T), bottom quarks. The resulting muon spectrum from heavy flavor decays is compared to PYTHIA and a next-to-leading-order perturbative QCD calculation. PYTHIA is used to determine the charm quark spectrum that would produce the observed muon excess. The corresponding differential cross section for charm quark production at forward rapidity is determined to be d sigma(c (c) over bar)/dy|(y=1.6)=0.243 +/- 0.013(stat.)+/- 0.105(data syst.)(-0.087)(+0.049)(PYTHIA syst.) mb.
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28. |
- Adler, S. S., et al.
(author)
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Dense-medium modifications to jet-induced hadron pair distributions in Au+Au collisions at root(NN)-N-S=200 GeV
- 2006
-
In: Physical Review Letters. - 1079-7114. ; 97:5
-
Journal article (peer-reviewed)abstract
- Azimuthal correlations of jet-induced high-p(T) charged hadron pairs are studied at midrapidity in Au+Au collisions at root s(NN)=200 GeV. The distribution of jet-associated partner hadrons (1.0 < p(T)< 2.5 GeV/c) per trigger hadron (2.5 < p(T)< 4.0 GeV/c) is found to vary with collision centrality, in both shape and yield, indicating a significant effect of the nuclear collision medium on the jet fragmentation process.
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29. |
- Adcox, K, et al.
(author)
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Formation of dense partonic matter in relativistic nucleus-nucleus collisions at RHIC: Experimental evaluation by the PHENIX Collaboration
- 2005
-
In: Nuclear Physics, Section A. - : Elsevier BV. - 0375-9474. ; 757:1-2, s. 184-283
-
Research review (peer-reviewed)abstract
- Extensive experimental data from high-energy nucleus-nucleus collisions were recorded using the PHENIX detector at the Relativistic Heavy Ion Collider (RHIC). The comprehensive set of measurements from the first three years of RHIC operation includes charged particle multiplicities, transverse energy, yield ratios and spectra of identified hadrons in a wide range of transverse momenta (PT), elliptic flow, two-particle correlations, nonstatistical fluctuations, and suppression of particle production at high PT. The results are examined with an emphasis on implications for the formation of a new state of dense matter. We find that the state of matter created at RHIC cannot be described in terms of ordinary color neutral hadrons.
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30. |
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31. |
- Abbasi, R., et al.
(author)
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Neutrino Analysis of the 2010 September Crab Nebula Flare and Time-Integrated Constraints on Neutrino Emission from the Crab Using Icecube
- 2012
-
In: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 745:1, s. 45-
-
Journal article (peer-reviewed)abstract
- We present the results of a search for high-energy muon neutrinos with the IceCube detector in coincidence with the Crab Nebula flare reported on 2010 September by various experiments. Due to the unusual flaring state of the otherwise steady source we performed a prompt analysis of the 79-string configuration data to search for neutrinos that might be emitted along with the observed. gamma-rays. We performed two different and complementary data selections of neutrino events in the time window of 10 days around the flare. One event selection is optimized for discovery of E-upsilon(2). neutrino spectrum typical of first-order Fermi acceleration. A similar event selection has also been applied to the 40-string data to derive the time-integrated limits to the neutrino emission from the Crab. The other event selection was optimized for discovery of neutrino spectra with softer spectral index and TeV energy cutoffs as observed for various Galactic sources in. gamma-rays. The 90% confidence level (CL) best upper limits on the Crab flux during the 10 day flare are 4.73 x 10(-11) cm(-2) s(-1) TeV-1 for an E-upsilon(2). neutrino spectrum and 2.50 x 10(-10) cm(-2) s(-1) TeV-1 for a softer neutrino spectra of E-upsilon(-2.7), as indicated by Fermi measurements during the flare. In this paper, we also illustrate the impact of the time-integrated limit on the Crab neutrino steady emission. The limit obtained using 375.5 days of the 40-string configuration is compared to existing models of neutrino production from the Crab and its impact on astrophysical parameters is discussed. The most optimistic predictions of some models are already rejected by the IceCube neutrino telescope with more than 90% CL.
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32. |
- Abbasi, R., et al.
(author)
-
Observation of anisotropy in the arrival directions of galactic cosmic rays at multiple angular scales with IceCube
- 2011
-
In: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 740:1, s. 16-
-
Journal article (peer-reviewed)abstract
- Between 2009 May and 2010 May, the IceCube neutrino detector at the South Pole recorded 32 billion muons generated in air showers produced by cosmic rays with a median energy of 20 TeV. With a data set of this size, it is possible to probe the southern sky for per-mil anisotropy on all angular scales in the arrival direction distribution of cosmic rays. Applying a power spectrum analysis to the relative intensity map of the cosmic ray flux in the southern hemisphere, we show that the arrival direction distribution is not isotropic, but shows significant structure on several angular scales. In addition to previously reported large-scale structure in the form of a strong dipole and quadrupole, the data show small-scale structure on scales between 15 degrees and 30 degrees. The skymap exhibits several localized regions of significant excess and deficit in cosmic ray intensity. The relative intensity of the smaller-scale structures is about a factor of five weaker than that of the dipole and quadrupole structure. The most significant structure, an excess localized at (right ascension alpha = 122 degrees.4 and declination d = -47 degrees.4), extends over at least 20 degrees in right ascension and has a post-trials significance of 5.3 sigma. The origin of this anisotropy is still unknown.
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33. |
- Abbasi, R., et al.
(author)
-
Search for a diffuse flux of astrophysical muon neutrinos with the IceCube 40-string detector
- 2011
-
In: Physical Review D. - 1550-7998 .- 1550-2368. ; 84:8, s. 082001-
-
Journal article (peer-reviewed)abstract
- The IceCube Neutrino Observatory is a 1 km(3) detector currently taking data at the South Pole. One of the main strategies used to look for astrophysical neutrinos with IceCube is the search for a diffuse flux of high-energy neutrinos from unresolved sources. A hard energy spectrum of neutrinos from isotropically distributed astrophysical sources could manifest itself as a detectable signal that may be differentiated from the atmospheric neutrino background by spectral measurement. This analysis uses data from the IceCube detector collected in its half completed configuration which operated between April 2008 and May 2009 to search for a diffuse flux of astrophysical muon neutrinos. A total of 12 877 upward-going candidate neutrino events have been selected for this analysis. No evidence for a diffuse flux of astrophysical muon neutrinos was found in the data set leading to a 90% C. L. upper limit on the normalization of an E(-2) astrophysical nu(mu) flux of 8.9 x 10(-9) GeV cm(-2) s(-1) sr(-1). The analysis is sensitive in the energy range between 35 TeV and 7 PeV. The 12 877 candidate neutrino events are consistent with atmospheric muon neutrinos measured from 332 GeV to 84 TeV and no evidence for a prompt component to the atmospheric neutrino spectrum is found.
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34. |
- Abbasi, R., et al.
(author)
-
Background studies for acoustic neutrino detection at the South Pole
- 2012
-
In: Astroparticle physics. - : Elsevier BV. - 0927-6505 .- 1873-2852. ; 35:6, s. 312-324
-
Journal article (peer-reviewed)abstract
- The detection of acoustic signals from ultra-high energy neutrino interactions is a promising method to measure the flux of cosmogenic neutrinos expected on Earth. The energy threshold for this process depends strongly on the absolute noise level in the target material. The South Pole Acoustic Test Setup (SPATS), deployed in the upper part of four boreholes of the IceCube Neutrino Observatory, has monitored the noise in Antarctic ice at the geographic South Pole for more than two years down to 500 m depth. The noise is very stable and Gaussian distributed. Lacking an in situ calibration up to now, laboratory measurements have been used to estimate the absolute noise level in the 10-50 kHz frequency range to be smaller than 20 mPa. Using a threshold trigger, sensors of the South Pole Acoustic Test Setup registered acoustic events in the IceCube detector volume and its vicinity. Acoustic signals from refreezing IceCube holes and from anthropogenic sources have been used to test the localization of acoustic events. An upper limit on the neutrino flux at energies E-v>10(11) GeV is derived from acoustic data taken over eight months. (C) 2011 Elsevier B.V. All rights reserved.
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35. |
- Abbasi, R., et al.
(author)
-
Constraints on the extremely-high energy cosmic neutrino flux with the IceCube 2008-2009 data
- 2011
-
In: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 1550-7998 .- 1550-2368. ; 83:9, s. 092003-
-
Journal article (peer-reviewed)abstract
- We report on a search for extremely-high energy neutrinos with energies greater than 10(6) GeV using the data taken with the IceCube detector at the South Pole. The data was collected between April 2008 and May 2009 with the half-completed IceCube array. The absence of signal candidate events in the sample of 333.5 days of live time significantly improves model-independent limits from previous searches and allows to place a limit on the diffuse flux of cosmic neutrinos with an E-2 spectrum in the energy range 2.0 x 10(6) - 6.3 x 10(9) GeV to a level of E-2 phi <= 3.6 x 10(-8) GeV cm(-2) sec(-1) sr(-1).
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36. |
- Abbasi, R., et al.
(author)
-
Time-dependent searches for point sources of neutrinos with the 40-string and 22-string configurations of IceCube
- 2012
-
In: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 744:1, s. 1-
-
Journal article (peer-reviewed)abstract
- This paper presents four searches for flaring sources of neutrinos using the IceCube neutrino telescope. For the first time, a search is performed over the entire parameter space of energy, direction, and time with sensitivity to neutrino flares lasting between 20 mu s and a year duration from astrophysical sources. Searches that integrate over time are less sensitive to flares because they are affected by a larger background of atmospheric neutrinos and muons that can be reduced by the use of additional timing information. Flaring sources considered here, such as active galactic nuclei, soft gamma-ray repeaters, and gamma-ray bursts, are promising candidate neutrino emitters. Two searches are "untriggered" in the sense that they look for any possible flare in the entire sky and from a predefined catalog of sources from which photon flares have been recorded. The other two searches are triggered by multi-wavelength information on flares from blazars and from a soft gamma-ray repeater. One triggered search uses lightcurves from Fermi-LAT which provides continuous monitoring. A second triggered search uses information where the flux states have been measured only for short periods of time near the flares. The untriggered searches use data taken by 40 strings of IceCube between 2008 April 5 and 2009 May 20. The triggered searches also use data taken by the 22-string configuration of IceCube operating between 2007 May 31 and 2008 April 5. The results from all four searches are compatible with a fluctuation of the background.
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37. |
- Adcox, K, et al.
(author)
-
PHENIX detector overview
- 2003
-
In: Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. - 0167-5087. ; 499:2-3, s. 469-479
-
Journal article (peer-reviewed)abstract
- The PHENIX detector is designed to perform a broad study of A-A, p-A, and p-p collisions to investigate nuclear matter under extreme conditions. A wide variety of probes, sensitive to all timescales, are used to study systematic variations with species and energy as well as to measure the spin structure of the nucleon. Designing for the needs of the heavy-ion and polarized-proton programs has produced a detector with unparalleled capabilities. PHENIX measures electron and muon pairs, photons, and hadrons with excellent energy and momentum resolution. The detector consists of a large number of subsystems that are discussed in other papers in this volume. The overall design parameters of the detector are presented. (C) 2002 Elsevier Science B.V. All rights reserved.
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38. |
- Abbasi, R., et al.
(author)
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First search for atmospheric and extraterrestrial neutrino-induced cascades with the IceCube detector
- 2011
-
In: Physical Review D. - 1550-7998 .- 1550-2368. ; 84:7, s. 072001-
-
Journal article (peer-reviewed)abstract
- We report on the first search for atmospheric and for diffuse astrophysical neutrino-induced showers (cascades) in the IceCube detector using 257 days of data collected in the year 2007-2008 with 22 strings active. A total of 14 events with energies above 16 TeV remained after event selections in the diffuse analysis, with an expected total background contribution of 8.3 +/- 3.6. At 90% confidence we set an upper limit of E(2)Phi(90%CL) < 3.6 x 10(-7) GeV.cm(-2).s(-1).sr(-1) on the diffuse flux of neutrinos of all flavors in the energy range between 24 TeV and 6.6 PeV assuming that Phi proportional to E(-2) and the flavor composition of the nu(e):nu(mu):nu(tau) flux is 1:1:1 at the Earth. The atmospheric neutrino analysis was optimized for lower energies. A total of 12 events were observed with energies above 5 TeV. The observed number of events is consistent with the expected background, within the uncertainties.
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39. |
- Abbasi, R., et al.
(author)
-
Limits on Neutrino Emission from Gamma-Ray Bursts with the 40 String IceCube Detector
- 2011
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 106:14, s. 141101-
-
Journal article (peer-reviewed)abstract
- IceCube has become the first neutrino telescope with a sensitivity below the TeV neutrino flux predicted from gamma-ray bursts if gamma-ray bursts are responsible for the observed cosmic-ray flux above 10(18) eV. Two separate analyses using the half-complete IceCube detector, one a dedicated search for neutrinos from p gamma interactions in the prompt phase of the gamma-ray burst fireball and the other a generic search for any neutrino emission from these sources over a wide range of energies and emission times, produced no evidence for neutrino emission, excluding prevailing models at 90% confidence.
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40. |
- Abbasi, R., et al.
(author)
-
Search for dark matter from the Galactic halo with the IceCube Neutrino Telescope
- 2011
-
In: Physical Review D. - 1550-7998 .- 1550-2368. ; 84:2, s. 022004-
-
Journal article (peer-reviewed)abstract
- Self-annihilating or decaying dark matter in the Galactic halo might produce high energy neutrinos detectable with neutrino telescopes. We have conducted a search for such a signal using 276 days of data from the IceCube 22-string configuration detector acquired during 2007 and 2008. The effect of halo model choice in the extracted limit is reduced by performing a search that considers the outer halo region and not the Galactic Center. We constrain any large-scale neutrino anisotropy and are able to set a limit on the dark matter self-annihilation cross section of h similar or equal to 10(-22) cm(3) s(-1) for weakly interacting massive particle masses above 1 TeV, assuming a monochromatic neutrino line spectrum.
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41. |
- Abbasi, R., et al.
(author)
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The IceCube data acquisition system : Signal capture, digitization, and timestamping
- 2009
-
In: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 601:3, s. 294-316
-
Journal article (peer-reviewed)abstract
- IceCube is a km-scale neutrino observatory under construction at the South Pole with sensors both in the deep ice (InIce) and on the surface (IceTop). The sensors, called Digital Optical Modules (DOMs). detect, digitize and timestamp the signals from optical Cherenkov-radiation photons. The DOM Main Board (MB) data acquisition subsystem is connected to the central DAQ in the IceCube Laboratory (ICL) by a single twisted copper wire-pair and transmits packetized data on demand. Time calibration is maintained throughout the array by regular transmission to the DOMs of precisely timed analog signals, synchronized to a central GPS-disciplined clock. The design goals and consequent features, functional capabilities, and initial performance of the DOM MB, and the operation of a combined array of DOMs as a system, are described here. Experience with the first InIce strings and the IceTop stations indicates that the system design and performance goals have been achieved. (c) 2009 Elsevier B.V. All rights reserved.
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42. |
- Abbasi, R., et al.
(author)
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Time-integrated Searches for Point-like Sources of Neutrinos with the 40-string IceCube Detector
- 2011
-
In: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 732:1, s. 18-
-
Journal article (peer-reviewed)abstract
- We present the results of time-integrated searches for astrophysical neutrino sources in both the northern and southern skies. Data were collected using the partially completed IceCube detector in the 40-string configuration recorded between 2008 April 5 and 2009 May 20, totaling 375.5 days livetime. An unbinned maximum likelihood ratio method is used to search for astrophysical signals. The data sample contains 36,900 events: 14,121 from the northern sky, mostly muons induced by atmospheric neutrinos, and 22,779 from the southern sky, mostly high-energy atmospheric muons. The analysis includes searches for individual point sources and stacked searches for sources in a common class, sometimes including a spatial extent. While this analysis is sensitive to TeV-PeV energy neutrinos in the northern sky, it is primarily sensitive to neutrinos with energy greater than about 1 PeV in the southern sky. No evidence for a signal is found in any of the searches. Limits are set for neutrino fluxes from astrophysical sources over the entire sky and compared to predictions. The sensitivity is at least a factor of two better than previous searches (depending on declination), with 90% confidence level muon neutrino flux upper limits being between E(2)d Phi/dE similar to 2-200 x 10(-12) TeV cm(-2) s(-1) in the northern sky and between 3-700 x 10(-12) TeV cm(-2) s(-1) in the southern sky. The stacked source searches provide the best limits to specific source classes. The full IceCube detector is expected to improve the sensitivity to d Phi/dE proportional to E-2 sources by another factor of two in the first year of operation.
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43. |
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44. |
- Abbasi, R., et al.
(author)
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Constraints on high-energy neutrino emission from SN 2008D
- 2011
-
In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 527:4, s. A28-
-
Journal article (peer-reviewed)abstract
- SN 2008D, a core collapse supernova at a distance of 27 Mpc, was serendipitously discovered by the Swift satellite through an associated X-ray flash. Core collapse supernovae have been observed in association with long gamma-ray bursts and X-ray flashes and a physical connection is widely assumed. This connection could imply that some core collapse supernovae possess mildly relativistic jets in which high-energy neutrinos are produced through proton-proton collisions. The predicted neutrino spectra would be detectable by Cherenkov neutrino detectors like IceCube. A search for a neutrino signal in temporal and spatial correlation with the observed X-ray flash of SN 2008D was conducted using data taken in 2007-2008 with 22 strings of the IceCube detector. Events were selected based on a boosted decision tree classifier trained with simulated signal and experimental background data. The classifier was optimized to the position and a "soft jet" neutrino spectrum assumed for SN 2008D. Using three search windows placed around the X-ray peak, emission time scales from 100-10 000 s were probed. No events passing the cuts were observed in agreement with the signal expectation of 0.13 events. Upper limits on the muon neutrino flux from core collapse supernovae were derived for different emission time scales and the principal model parameters were constrained. While no meaningful limits can be given in the case of an isotropic neutrino emission, the parameter space for a jetted emission can be constrained. Future analyses with the full 86 string IceCube detector could detect up to similar to 100 events for a core-collapse supernova at 10 Mpc according to the soft jet model.
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45. |
- Abbasi, R., et al.
(author)
-
Measurement of the atmospheric neutrino energy spectrum from 100 GeV to 400 TeV with IceCube
- 2011
-
In: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 1550-7998 .- 1550-2368. ; 83:1, s. 012001-
-
Journal article (peer-reviewed)abstract
- A measurement of the atmospheric muon neutrino energy spectrum from 100 GeV to 400 TeV was performed using a data sample of about 18 000 up-going atmospheric muon neutrino events in IceCube. Boosted decision trees were used for event selection to reject misreconstructed atmospheric muons and obtain a sample of up-going muon neutrino events. Background contamination in the final event sample is less than 1%. This is the first measurement of atmospheric neutrinos up to 400 TeV, and is fundamental to understanding the impact of this neutrino background on astrophysical neutrino observations with IceCube. The measured spectrum is consistent with predictions for the atmospheric nu(mu) + (nu) over bar (mu) flux.
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46. |
- Abbasi, R., et al.
(author)
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Search for a Lorentz-violating sidereal signal with atmospheric neutrinos in IceCube
- 2010
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In: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 1550-7998. ; 82, s. 112003-
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Journal article (peer-reviewed)abstract
- A search for sidereal modulation in the flux of atmospheric muon neutrinos in IceCube was performed. Such a signal could be an indication of Lorentz-violating physics. Neutrino oscillation models, derivable from extensions to the standard model, allow for neutrino oscillations that depend on the neutrino's direction of propagation. No such direction-dependent variation was found. A discrete Fourier transform method was used to constrain the Lorentz and CPT-violating coefficients in one of these models. Because of the unique high energy reach of IceCube, it was possible to improve constraints on certain Lorentz-violating oscillations by 3 orders of magnitude with respect to limits set by other experiments.
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47. |
- Adler, SS, et al.
(author)
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Single electrons from heavy-flavor decays in p + p collisions at root s=200 GeV
- 2006
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In: Physical Review Letters. - 1079-7114. ; 96:3
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Journal article (peer-reviewed)abstract
- The invariant differential cross section for inclusive electron production in p+p collisions at root s=200 GeV has been measured by the PHENIX experiment at the BNL Relativistic Heavy Ion Collider over the transverse momentum range 0.4 <= p(T) <= 5.0 GeV/c in the central rapidity region (vertical bar eta vertical bar <= 0.35). The contribution to the inclusive electron spectrum from semileptonic decays of hadrons carrying heavy flavor, i.e., charm quarks or, at high p(T), bottom quarks, is determined via three independent methods. The resulting electron spectrum from heavy-flavor decays is compared to recent leading and next-to-leading order perturbative QCD calculations. The total cross section of charm quark-antiquark pair production is determined to be sigma(c (c) over bar) = 0.92 +/- 0.15(stat) +/- 0.54(syst) mb.
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48. |
- Namkoong, H, et al.
(author)
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DOCK2 is involved in the host genetics and biology of severe COVID-19
- 2022
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In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 609:7928, s. 754-
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Journal article (peer-reviewed)abstract
- Identifying the host genetic factors underlying severe COVID-19 is an emerging challenge1–5. Here we conducted a genome-wide association study (GWAS) involving 2,393 cases of COVID-19 in a cohort of Japanese individuals collected during the initial waves of the pandemic, with 3,289 unaffected controls. We identified a variant on chromosome 5 at 5q35 (rs60200309-A), close to the dedicator of cytokinesis 2 gene (DOCK2), which was associated with severe COVID-19 in patients less than 65 years of age. This risk allele was prevalent in East Asian individuals but rare in Europeans, highlighting the value of genome-wide association studies in non-European populations. RNA-sequencing analysis of 473 bulk peripheral blood samples identified decreased expression of DOCK2 associated with the risk allele in these younger patients. DOCK2 expression was suppressed in patients with severe cases of COVID-19. Single-cell RNA-sequencing analysis (n = 61 individuals) identified cell-type-specific downregulation of DOCK2 and a COVID-19-specific decreasing effect of the risk allele on DOCK2 expression in non-classical monocytes. Immunohistochemistry of lung specimens from patients with severe COVID-19 pneumonia showed suppressed DOCK2 expression. Moreover, inhibition of DOCK2 function with CPYPP increased the severity of pneumonia in a Syrian hamster model of SARS-CoV-2 infection, characterized by weight loss, lung oedema, enhanced viral loads, impaired macrophage recruitment and dysregulated type I interferon responses. We conclude that DOCK2 has an important role in the host immune response to SARS-CoV-2 infection and the development of severe COVID-19, and could be further explored as a potential biomarker and/or therapeutic target.
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49. |
- Abbasi, R., et al.
(author)
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The energy spectrum of atmospheric neutrinos between 2 and 200 TeV with the AMANDA-II detector
- 2010
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In: Astroparticle physics. - : Elsevier BV. - 0927-6505 .- 1873-2852. ; 34:1, s. 48-58
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Journal article (peer-reviewed)abstract
- The muon and anti-muon neutrino energy spectrum is determined from 2000-2003 AMANDA telescope data using regularised unfolding. This is the first measurement of atmospheric neutrinos in the energy range 2-200 TeV. The result is compared to different atmospheric neutrino models and it is compatible with the atmospheric neutrinos from pion and kaon decays. No significant contribution from charm had-ron decays or extraterrestrial neutrinos is detected. The capabilities to improve the measurement of the neutrino spectrum with the successor experiment IceCube are discussed.
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50. |
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