| 1. |
|
|
| 2. |
- Beal, Jacob, et al.
(author)
-
Robust estimation of bacterial cell count from optical density
- 2020
-
In: Communications Biology. - : Springer Science and Business Media LLC. - 2399-3642. ; 3:1
-
Journal article (peer-reviewed)abstract
- Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data.
|
|
| 3. |
|
|
| 4. |
-
- 2019
-
Journal article (peer-reviewed)
|
|
| 5. |
|
|
| 6. |
|
|
| 7. |
|
|
| 8. |
- Niemi, MEK, et al.
(author)
-
- 2021
-
swepub:Mat__t
|
|
| 9. |
|
|
| 10. |
- Campbell, PJ, et al.
(author)
-
Pan-cancer analysis of whole genomes
- 2020
-
In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 578:7793, s. 82-
-
Journal article (peer-reviewed)abstract
- Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale1–3. Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4–5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter4; identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation5,6; analyses timings and patterns of tumour evolution7; describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity8,9; and evaluates a range of more-specialized features of cancer genomes8,10–18.
|
|
| 11. |
- Klionsky, Daniel J., et al.
(author)
-
Guidelines for the use and interpretation of assays for monitoring autophagy
- 2012
-
In: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 8:4, s. 445-544
-
Research review (peer-reviewed)abstract
- In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. A key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process vs. those that measure flux through the autophagy pathway (i.e., the complete process); thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated from stimuli that result in increased autophagic activity, defined as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (in most higher eukaryotes and some protists such as Dictyostelium) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the field understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field.
|
|
| 12. |
- Flannick, Jason, et al.
(author)
-
Data Descriptor : Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
- 2017
-
In: Scientific Data. - : Springer Science and Business Media LLC. - 2052-4463. ; 4
-
Journal article (peer-reviewed)abstract
- To investigate the genetic basis of type 2 diabetes (T2D) to high resolution, the GoT2D and T2D-GENES consortia catalogued variation from whole-genome sequencing of 2,657 European individuals and exome sequencing of 12,940 individuals of multiple ancestries. Over 27M SNPs, indels, and structural variants were identified, including 99% of low-frequency (minor allele frequency [MAF] 0.1-5%) non-coding variants in the whole-genome sequenced individuals and 99.7% of low-frequency coding variants in the whole-exome sequenced individuals. Each variant was tested for association with T2D in the sequenced individuals, and, to increase power, most were tested in larger numbers of individuals (> 80% of low-frequency coding variants in similar to ~82 K Europeans via the exome chip, and similar to ~90% of low-frequency non-coding variants in similar to ~44 K Europeans via genotype imputation). The variants, genotypes, and association statistics from these analyses provide the largest reference to date of human genetic information relevant to T2D, for use in activities such as T2D-focused genotype imputation, functional characterization of variants or genes, and other novel analyses to detect associations between sequence variation and T2D.
|
|
| 13. |
- Fuchsberger, Christian, et al.
(author)
-
The genetic architecture of type 2 diabetes
- 2016
-
In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 536:7614, s. 41-47
-
Journal article (peer-reviewed)abstract
- The genetic architecture of common traits, including the number, frequency, and effect sizes of inherited variants that contribute to individual risk, has been long debated. Genome-wide association studies have identified scores of common variants associated with type 2 diabetes, but in aggregate, these explain only a fraction of the heritability of this disease. Here, to test the hypothesis that lower-frequency variants explain much of the remainder, the GoT2D and T2D-GENES consortia performed whole-genome sequencing in 2,657 European individuals with and without diabetes, and exome sequencing in 12,940 individuals from five ancestry groups. To increase statistical power, we expanded the sample size via genotyping and imputation in a further 111,548 subjects. Variants associated with type 2 diabetes after sequencing were overwhelmingly common and most fell within regions previously identified by genome-wide association studies. Comprehensive enumeration of sequence variation is necessary to identify functional alleles that provide important clues to disease pathophysiology, but large-scale sequencing does not support the idea that lower-frequency variants have a major role in predisposition to type 2 diabetes.
|
|
| 14. |
- Aaltonen, T., et al.
(author)
-
Combination of Tevatron Searches for the Standard Model Higgs Boson in the W+W- Decay Mode
- 2010
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 104:6, s. 061802-
-
Journal article (peer-reviewed)abstract
- We combine searches by the CDF and D0 Collaborations for a Higgs boson decaying to W+W-. The data correspond to an integrated total luminosity of 4.8 (CDF) and 5.4 (D0) fb(-1) of p (p) over bar collisions at root s = 1.96 TeV at the Fermilab Tevatron collider. No excess is observed above background expectation, and resulting limits on Higgs boson production exclude a standard model Higgs boson in the mass range 162-166 GeV at the 95% C.L.
|
|
| 15. |
|
|
| 16. |
|
|
| 17. |
- Abazov, V. M., et al.
(author)
-
A combined search for the standard model Higgs boson at root S=1.96 TeV
- 2008
-
In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 663:1-2, s. 26-36
-
Journal article (peer-reviewed)abstract
- We present new results of the search for WH --> lvb (b) over bar production in p (p) over bar collisions at a center-of-mass energy of root S = 1.96 TeV, based on a dataset with integrated luminosity of 0.44 fb(-1). We combine these new results with previously published searches by the DO collaboration, for WH and ZH production analyzed in the E(T)b (b) over bar final state, for ZH (--> l(+)l(-)b (b) over bar) production, for WH (-->. WWW) production, and for H (--> W W) direct production. No signal-like excess is observed either in the W H analysis or in the combination of all D0 Higgs boson analyses. We set 95% C.L. (expected) upper limits on sigma(p (p) over bar --> WH) x B(H --> b (b) over bar) ranging from 1.6 (2.2) ph to 1.9 (3.3) pb for Higgs boson masses between 105 and 145 GeV, to be compared to the theoretical prediction of 0.13 pb for a Standard Model (SM) Higgs boson with mass in m(H) = 115 GeV. After combination with the other DO Higgs boson searches, we obtain for in H = 115 GeV an observed (expected) limit 8.5 (12.1) times higher than the SM predicted Higgs boson production cross section. For m(H) = 160 GeV, the corresponding observed (expected) ratio is 10.2 (9.0).
|
|
| 18. |
- Abazov, V. M., et al.
(author)
-
Combined D0 measurements constraining the CP-violating phase and width difference in the B-s(0) system
- 2007
-
In: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 1550-7998. ; 76:5, s. 057101-
-
Journal article (peer-reviewed)abstract
- We combine the D0 measurement of the width difference between the light and heavy B-s(0) mass eigenstates and of the CP-violating mixing phase determined from the time-dependent angular distributions in the B-s(0)-> J/psi phi decays along with the charge asymmetry in semileptonic decays also measured with the D0 detector. With the additional constraint from the world average of the flavor-specific B-s(0) lifetime, we obtain Delta Gamma(s)equivalent to(Gamma(L)-Gamma(H))=0.13 +/- 0.09 ps(-1) and vertical bar phi(s)vertical bar=0.70(-0.47)(+0.39) or Delta Gamma(s)=-0.13 +/- 0.09 ps(-1) and vertical bar phi(s)vertical bar=2.44(-0.39)(+0.47). The data sample corresponds to an integrated luminosity of 1.1 fb(-1) accumulated with the D0 detector at the Fermilab Tevatron Collider.
|
|
| 19. |
- Abazov, V. M., et al.
(author)
-
Direct observation of the strange b baryon Xi(-)(b)
- 2007
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 99:5, s. 052001-
-
Journal article (peer-reviewed)abstract
- We report the first direct observation of the strange b baryon Xi(-)(b)(Xi) over bar (+)(b)). We reconstruct the decay Xi(-)(b)-->J/psi Xi(-), with J/psi-->mu(+)mu(-), and Xi(-)-->Lambda pi(-)-->p pi(-)pi(-) in p (p) over bar collisions at root s = 1.96 TeV. Using 1.3 fb(-1) of data collected by the D0 detector, we observe 15.2 +/- 4.4(stat)(-0.4)(+1.9)(syst) Xi(-)(b) candidates at a mass of 5.774 +/- 0.011(stat) +/- 0.015(syst) GeV. The significance of the observed signal is 5.5 sigma, equivalent to a probability of 3.3 x 10(-8) of it arising from a background fluctuation. Normalizing to the decay Lambda(b)-->J/psi Lambda, we measure the relative rate sigma(Xi(-)(b))xB(Xi(-)(b)-->J/psi Xi)/ sigma(Lambda(b))xB(Lambda(b)-->J/psi Lambda) = 0.28 +/- 0.09(stat)(-0.08)(+0.09)(syst).
|
|
| 20. |
- Abazov, V. M., et al.
(author)
-
Evidence for production of single top quarks
- 2008
-
In: Physical Review D. - 1550-7998 .- 1550-2368. ; D:78, s. 012005-
-
Research review (peer-reviewed)abstract
- We present first evidence for the production of single top quarks in the D0 detector at the Fermilab Tevatron p (p) over bar collider. The standard model predicts that the electroweak interaction can produce a top quark together with an antibottom quark or light quark, without the antiparticle top-quark partner that is always produced from strong-coupling processes. Top quarks were first observed in pair production in 1995, and since then, single top-quark production has been searched for in ever larger data sets. In this analysis, we select events from a 0.9 fb(-1) data set that have an electron or muon and missing transverse energy from the decay of a W boson from the top-quark decay, and two, three, or four jets, with one or two of the jets identified as originating from a b hadron decay. The selected events are mostly backgrounds such as W + jets and t (t) over bar events, which we separate from the expected signals using three multivariate analysis techniques: boosted decision trees, Bayesian neural networks, and matrix-element calculations. A binned likelihood fit of the signal cross section plus background to the data from the combination of the results from the three analysis methods gives a cross section for single top-quark production of sigma(p (p) over bar -> tb + X, tqb + X) = 4.7 +/- 1.3 pb. The probability to measure a cross section at this value or higher in the absence of signal is 0.014%, corresponding to a 3.6 standard deviation significance. The measured cross section value is compatible at the 10% level with the standard model prediction for electroweak top-quark production. We use the cross section measurement to directly determine the Cabibbo-Kobayashi-Maskawa quark mixing matrix element that describes the Wtb coupling and find vertical bar V(tb)f(1)(L)vertical bar = 1.31(-0.21)(+0.25), where f(1)(L) is a generic vector coupling. This model-independent measurement translates into 0.68 <= 1 at the 95% C.L. in the standard model.
|
|
| 21. |
|
|
| 22. |
- Abazov, V. M., et al.
(author)
-
Lifetime difference and CP-violating phase in the B-s(0) system
- 2007
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 98:12, s. 121801-
-
Journal article (peer-reviewed)abstract
- From an analysis of the decay B-s(0)-> J/psi phi, we obtain the width difference between the light and heavy mass eigenstates Delta Gamma equivalent to(Gamma(L)-Gamma(H))=0.17 +/- 0.09(stat)+/- 0.02(syst) ps(-1) and the CP-violating phase phi(s)=-0.79 +/- 0.56(stat)(-0.01)(+0.14)(syst). Under the hypothesis of no CP violation (phi(s)equivalent to 0), we obtain 1/Gamma=tau/(B-s(0))=1.52 +/- 0.08(stat)(-0.03)(+0.01)(syst) ps and Delta Gamma=0.12(-0.10)(+0.08)(stat)+/- 0.02(syst) ps(-1). The data sample corresponds to an integrated luminosity of about 1.1 fb(-1) accumulated with the D0 detector at the Fermilab Tevatron collider. This is the first direct measurement of the CP-violating mixing phase in the B-s(0) system.
|
|
| 23. |
- Abazov, V. M., et al.
(author)
-
Measurement of the differential cross section for the production of an isolated photon with associated jet in p(p)over-bar collisions at root s=1.96 TeV
- 2008
-
In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 666:5, s. 435-445
-
Journal article (peer-reviewed)abstract
- The process p (p) over bar -> gamma + jet + X is studied using 1.0 fb(-1) of data collected by the DO detector at the Fermilab Tevatron p (p) over bar collider at a center-of-mass energy root s = 1.96 TeV. Photons are reconstructed in the central rapidity region vertical bar y(gamma)vertical bar < 1.0 with transverse momenta in the range 30 < p(T)(gamma) < 400 GeV while jets are reconstructed in either the central vertical bar y(jet)vertical bar < 0.8 or forward 1.5 < vertical bar y(jet)vertical bar < 2.5 rapidity intervals with P-T(jet) > 15 GeV. The differential cross section d(3 sigma)/dp(T)(gamma) dy(gamma) dy(jet) is measured as a function of p(T)(gamma) in four regions, differing by the relative orientations of the photon and the jet in rapidity. Ratios between the differential cross sections in each region are also presented. Next-to-leading order QCD predictions using different parameterizations of parton distribution functions and theoretical scale choices are compared to the data. The predictions do not simultaneously describe the measured normalization and p(T)(gamma) dependence of the cross section in the four measured regions.
|
|
| 24. |
- Abazov, V. M., et al.
(author)
-
Measurement of the forward-backward charge asymmetry in top-quark pair production
- 2008
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 100:14:100, s. 142002-
-
Journal article (peer-reviewed)abstract
- We present the first measurement of the integrated forward-backward charge asymmetry in top-quark-top-antiquark pair (t (t) over bar) production in proton-antiproton (p (p) over bar) collisions in the lepton+jets final state. Using a b-jet tagging algorithm and kinematic reconstruction assuming t (t) over bar +X production and decay, a sample of 0.9 fb(-1) of data, collected by the D0 experiment at the Fermilab Tevatron Collider, is used to measure the asymmetry for different jet multiplicities. The result is also used to set upper limits on t (t) over bar +X production via a Z' resonance.
|
|
| 25. |
- Abazov, V. M., et al.
(author)
-
Measurement of the inclusive jet cross section in p(p)over-bar collisions at root s=1.96 TeV
- 2008
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 101:6, s. 062001-:101, s. 062001-
-
Journal article (peer-reviewed)abstract
- We report on a measurement of the inclusive jet cross section in p (p) over bar collisions at a center-of-mass energy root s = 1.96 TeV using data collected by the D0 experiment at the Fermilab Tevatron Collider corresponding to an integrated luminosity of 0: 70 fb(-1). The data cover jet transverse momenta from 50 to 600 GeV and jet rapidities in the range -2.4 to 2.4. Detailed studies of correlations between systematic uncertainties in transverse momentum and rapidity are presented, and the cross section measurements are found to be in good agreement with next-to-leading order QCD calculations.
|
|
| 26. |
- Abazov, V. M., et al.
(author)
-
Measurement of the Lambda(0)(b) lifetime using semileptonic decays
- 2007
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 99:18, s. 182001-
-
Journal article (peer-reviewed)abstract
- We report a measurement of the Lambda(0)(b) lifetime using a sample corresponding to 1.3 fb(-1) of data collected by the D0 experiment in 2002-2006 during run II of the Fermilab Tevatron collider. The Lambda(0)(b) baryon is reconstructed via the decay Lambda(0)(b)->mu(nu) over bar Lambda X-+(c). Using 4437 +/- 329 signal candidates, we measure the Lambda(0)(b) lifetime to be tau(Lambda(0)(b))=1.290(-0.110)(+0.119)(stat)(-0.091)(+0.087)(syst) ps, which is among the most precise measurements in semileptonic Lambda(0)(b) decays. This result is in good agreement with the world average value.
|
|
| 27. |
- Abazov, V. M., et al.
(author)
-
Measurement of the Lambda(b) lifetime in the exclusive decay Lambda(b)-> J/psi Lambda
- 2007
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 99:14, s. 142001-
-
Journal article (peer-reviewed)abstract
- We have measured the Lambda(b) lifetime using the exclusive decay Lambda(b)-> J/psi Lambda, based on 1.2 fb(-1) of data collected with the D0 detector during 2002-2006. From 171 reconstructed Lambda(b) decays, where the J/psi and Lambda are identified via the decays J/psi ->mu(+)mu(-) and Lambda -> p pi, we measured the Lambda(b) lifetime to be tau(Lambda(b))=1.218(-0.115)(+0.130)(stat)+/- 0.042(syst) ps. We also measured the B-0 lifetime in the decay B-0 -> J/psi(mu(+)mu(-))K-S(0)(pi(+)pi(-)) to be tau(B-0)=1.501(-0.074)(+0.078)(stat)+/- 0.050(syst) ps, yielding a lifetime ratio of tau(Lambda(b))/tau(B-0)=0.811(-0.087)(+0.096)(stat)+/- 0.034(syst).
|
|
| 28. |
- Abazov, V. M., et al.
(author)
-
Measurement of the Lifetime of the B-c(+/-) Meson in the Semileptonic Decay Channel
- 2009
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 102:9, s. 092001-
-
Journal article (peer-reviewed)abstract
- Using approximately 1.3 fb(-1) of data collected by the D0 detector between 2002 and 2006, we measure the lifetime of the B-c(+/-) meson in the B-c(+/-)-> J/psi mu(+/-)+X final state. A simultaneous unbinned likelihood fit to the J/psi+mu invariant mass and lifetime distributions yields a signal of 881 +/- 80(stat) candidates and a lifetime measurement of tau(B-c(+/-))=0.448(-0.036)(+0.038)(stat)+/- 0.032(syst) ps.
|
|
| 29. |
- Abazov, V. M., et al.
(author)
-
Measurement of the muon charge asymmetry from W boson decays
- 2008
-
In: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 1550-7998. ; D:77, s. 011106-
-
Journal article (peer-reviewed)abstract
- We present a measurement of the muon charge asymmetry from W boson decays using 0.3 fb(-1) of data collected at root s =1.96 GeV between 2002 and 2004 with the D0 detector at the Fermilab Tevatron (p) over bar Collider. We compare our findings with expectations from next-to-leading-order calculations performed using the CTEQ6.1M and MRST04 NLO parton distribution functions. Our findings can be used to constrain future parton distribution function fits.
|
|
| 30. |
- Abazov, V. M., et al.
(author)
-
Measurement of the p(p)over-bar -> WZ+X cross section at root s=1.96 TeV and limits on WWZ trilinear gauge couplings
- 2007
-
In: Physical Review D. - 1550-7998 .- 1550-2368. ; 76:11
-
Journal article (peer-reviewed)abstract
- We present measurements of the process p (P) over bar -> WZ + X -> l 'nu(l ')l (l) over bar at root s = 1:96 TeV,where l and l ' are electrons or muons. Using 1 fb(-1) of data from the D0 experiment, we observe 13 candidates with an expected background of 4.5 +/- 0.6 events and measure a cross section sigma(WZ) = 2.7(-1.3)(+1.7) pb. From the number of observed events and the Z boson transverse momentum distribution, we limit the trilinear WWZ gauge couplings to -0: 17 <= lambda(Z) <= 0.21 (Delta k(Z) <= 0.29(lambda(Z) = 0) at the 95% C.L. for a form factor scale Lambda = 2 TeV. Further, assuming that Delta g(1)(Z) = Delta k(Z), we find -0.12 <= Delta k(Z) <= 0.29(lambda(Z) = 0) at the 95% C. L. These are the most restrictive limits on the WWZ couplings available to date.
|
|
| 31. |
- Abazov, V. M., et al.
(author)
-
Measurement of the ratio of the p(p)over-bar -> W + c-jet cross section to the inclusive p(p)over-bar -> W + jets cross section
- 2008
-
In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 666:1, s. 23-30
-
Journal article (peer-reviewed)abstract
- We present a measurement of the fraction of inclusive W +jets events produced with net charm quantum number 11, denoted W + c-jet, in p collisions at root s = 1.96 TeV using approximately 1 fb(-1) of data collected by the DO detector at the Fermilab Tevatron Collider. We identify the W +jets events via the leptonic W boson decays. Candidate W + c-jet events are selected by requiring a jet containing a muon in association with a reconstructed W boson and exploiting the charge correlation between this muon and W boson decay lepton to perform a nearly model-independent background subtraction. We measure the fraction of W + c-jet events in the inclusive W +jets sample for jet PT > 20 GeV and pseudorapidity |eta| < 2.5 to be 0.074 +/- 0.019(stat.) +/-(0.012)(0.014) (syst.), in agreement with theoretical predictions. The probability that background fluctuations could produce the observed fraction of W + c-jet events is estimated to be 2.5 x 10(-4), which corresponds to a 3.5 sigma statistical significance. Published by Elsevier B.V.
|
|
| 32. |
- Abazov, V. M., et al.
(author)
-
Measurement of the Semileptonic Branching Ratio of Bs(0) to an Orbitally Excited D-s** State : Br(Bs(0) -> Ds1(-)(2536)mu(+)nu X)
- 2009
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 102:5, s. 051801-:102, s. 051801-
-
Journal article (peer-reviewed)abstract
- In a data sample of approximately 1.3 fb(-1) collected with the D0 detector between 2002 and 2006, the orbitally excited charm state D-s1(+/-)(2536) has been observed with a measured mass of 2535.7 +/- 0.6(stat) +/- 0.5(syst) MeV/c(2) via the decay mode B-s(0) -> D-s1(-)(2536)mu(+)nu X-mu. A first measurement is made of the branching ratio product Br((b) over bar -> D-s1(-)(2536)mu(+)nu X-mu) x Br(D-s1(-) -> D*K--(S)0). Assuming that D-s1(-)(2536) production in semileptonic decay is entirely from B-s(0), an extraction of the semileptonic branching ratio Br(B-s(0) -> D-s1(-)(2536)mu(+)nu X-mu) is made.
|
|
| 33. |
- Abazov, V. M., et al.
(author)
-
Measurement of the shape of the boson rapidity distribution for p(p)over-bar -> Z/gamma(*)-> e(+)e(-)+X events produced at root s of 1.96 TeV
- 2007
-
In: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 1550-7998. ; 76:1, s. 012003-
-
Journal article (peer-reviewed)abstract
- We present a measurement of the shape of the boson rapidity distribution for p (p) over bar -> Z/gamma(*)-> e(+)e(-)+X events at a center-of-mass energy of 1.96 TeV. The measurement is made for events with electron-positron mass 71 < M-ee < 111 GeV and uses 0.4 fb(-1) of data collected at the Fermilab Tevatron collider with the D0 detector. This measurement significantly reduces the uncertainties on the rapidity distribution in the forward region compared with previous measurements. Predictions of next-to-next-to-leading order (NNLO) QCD are found to agree well with the data over the full rapidity range.
|
|
| 34. |
- Abazov, V. M., et al.
(author)
-
Measurement of the shape of the boson-transverse momentum distribution in p(p)over-bar -> Z/gamma*-> e(+)e(-)+X events produced at root s=1.96 TeV
- 2008
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 100:10:100, s. 102002-
-
Journal article (peer-reviewed)abstract
- We present a measurement of the shape of the Z/gamma* boson transverse momentum (q(T)) distribution in p (p) over bar -> Z/gamma(*)-> e(+)e(-)+X events at a center-of-mass energy of 1.96 TeV using 0.98 fb(-1) of data collected with the D0 detector at the Fermilab Tevatron collider. The data are found to be consistent with the resummation prediction at low q(T), but above the perturbative QCD calculation in the region of q(T)> 30 GeV/c. Using events with q(T)< 30 GeV/c, we extract the value of g(2), one of the nonperturbative parameters for the resummation calculation. Data at large boson rapidity y are compared with the prediction of resummation and with alternative models that employ a resummed form factor with modifications in the small Bjorken x region of the proton wave function.
|
|
| 35. |
- Abazov, V. M., et al.
(author)
-
Measurement of the t(t)over-bar production cross section in p(p)over-bar collisions at root s=1.96 TeV
- 2008
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 100:19:100, s. 192004-
-
Journal article (peer-reviewed)abstract
- We measure the t (t) over bar production cross section in p (p) over bar collisions at root s = 1.96 TeV in the lepton + jets channel. Two complementary methods discriminate between signal and background: b tagging and a kinematic likelihood discriminant. Based on 0.9 fb(-1) of data collected by the D0 detector at the Fermilab Tevatron Collider, we measure sigma(t (t) over bar) = 7.62 +/- 0.85 pb, assuming the current world average m(t) = 172.6 GeV. We compare our cross section measurement with theory predictions to determine a value for the top-quark mass of 170 +/- 7 GeV.
|
|
| 36. |
- Abazov, V. M., et al.
(author)
-
Measurement of the t(t)over-bar production cross section in p(p)over-bar collisions at root s=1.96 TeV using kinematic characteristics of lepton plus jets events
- 2007
-
In: Physical Review D. - 1550-7998 .- 1550-2368. ; 76:9
-
Journal article (peer-reviewed)abstract
- We present a measurement of the top quark pair production cross section in p (p) over bar collisions at root s=1.96 TeV utilizing 425 pb(-1) of data collected with the D0 detector at the Fermilab Tevatron Collider. We consider the final state of the top quark pair containing one high-p(T) electron or muon and at least four jets. We exploit specific kinematic features of t (t) over bar events to extract the cross section. For a top quark mass of 175 GeV, we measure sigma(t (t) over bar)=6.4(-1.2)(+1.3)(stat)+/- 0.7(syst)+/- 0.4(lum) pb, in good agreement with the standard model prediction.
|
|
| 37. |
- Abazov, V. M., et al.
(author)
-
Measurement of the t(t)over-bar production cross section in p(p)over-bar collisions using dilepton events
- 2007
-
In: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 1550-7998. ; 76:5, s. 052006-
-
Journal article (peer-reviewed)abstract
- We present a measurement of the t (t) over bar pair production cross section in p (p) over bar collisions at root s=1.96 TeV utilizing approximately 425 pb(-1) of data collected with the D0 detector. We consider decay channels containing two high p(T) charged leptons (either e or mu) from leptonic decays of both top-daughter W bosons. These were gathered using four sets of selection criteria, three of which required that a pair of fully identified leptons (i.e., e mu, ee, or mu mu) be found. The fourth approach imposed less restrictive criteria on one of the lepton candidates and required that at least one hadronic jet in each event be tagged as containing a b quark. For a top quark mass of 175 GeV, the measured cross section is 7.4 +/- 1.4(stat)+/- 1.0(syst) pb and for the current Tevatron average top quark mass of 170.9 GeV, the resulting value of the cross section is 7.8 +/- 1.8(stat+syst) pb.
|
|
| 38. |
- Abazov, V. M., et al.
(author)
-
Model-independent measurement of the W-boson helicity in top-quark decays at D0
- 2008
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 100:6
-
Journal article (peer-reviewed)abstract
- We present the first model-independent measurement of the helicity of W bosons produced in top quark decays, based on a 1 fb(-1) sample of candidate t (t) over bar events in the dilepton and lepton plus jets channels collected by the D0 detector at the Fermilab Tevatron p (p) over bar Collider. We reconstruct the angle theta(*) between the momenta of the down-type fermion and the top quark in the W boson rest frame for each top quark decay. A fit of the resulting cos theta(*) distribution finds that the fraction of longitudinal W bosons f(0)=0.425 +/- 0.166(stat)+/- 0.102(syst) and the fraction of right-handed W bosons f(+)=0.119 +/- 0.090(stat)+/- 0.053(syst), which is consistent at the 30% C.L. with the standard model.
|
|
| 39. |
- Abazov, V. M., et al.
(author)
-
Observation and properties of the orbitally excited B-s2* meson
- 2008
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 100:8, s. 082002-:100, s. 082002-
-
Journal article (peer-reviewed)abstract
- We report the direct observation of the excited L=1 state B-s2* in fully reconstructed decays to B+K-. The mass of the B-s2* meson is measured to be 5839.6 +/- 1.1(stat)+/- 0.7(syst) MeV/c(2), and its production rate relative to the B+ meson is measured to be [1.15 +/- 0.23(stat)+/- 0.13(syst)]%.
|
|
| 40. |
- Abazov, V. M., et al.
(author)
-
Observation of the B-c meson in the exclusive decay B-c -> J/psi pi
- 2008
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 101:1, s. 012001-:101, s. 012001-
-
Journal article (peer-reviewed)abstract
- A fully reconstructed B-c -> J/psi pi signal is observed with the D0 detector at the Fermilab Tevatron p (p) over bar collider using 1.3 fb(-1) of integrated luminosity. The signal consists of 54 +/- 12 candidates with a significance that exceeds 5 standard deviations, and confirms earlier observations of this decay. The measured mass of the B-c meson is 6300 +/- 14(stat)+/- 5(syst) MeV/c(2).
|
|
| 41. |
- Abazov, V. M., et al.
(author)
-
Properties of l=1 B-1 and B*(2) Mesons
- 2007
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 99:17, s. 172001-
-
Journal article (peer-reviewed)abstract
- This Letter presents the first strong evidence for the resolution of the excited B mesons B-1 and B-2(*) as two separate states in fully reconstructed decays to B+(*())pi(-). The mass of B-1 is measured to be 5720.6 +/- 2.4 +/- 1.4 MeV/c(2) and the mass difference Delta M between B-2* and B-1 is 26.2 +/- 3.1 +/- 0: 9 MeV/c(2), giving the mass of the B-2* as 5746.8 +/- 2.4 +/- 1.7 MeV/c(2). The production rate for B-1 and B-2* mesons is determined to be a fraction (13.9 +/- 1.9 +/- 3.2)% of the production rate of the B+ meson.
|
|
| 42. |
- Abazov, V. M., et al.
(author)
-
Search for a Higgs boson produced in association with a Z boson in p(p)over-bar collisions
- 2007
-
In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 655:5-6, s. 209-216
-
Journal article (peer-reviewed)abstract
- We describe a search for the Standard Model Higgs boson with a mass of 105 GeV/c(2) to 145 GeV/c(2) in data corresponding to an integrated luminosity of approximately 450 pb(-1) collected with the D phi detector at the Fermilab Tevatron p (p) over bar collider at a center-of-mass energy of 1.96 TeV. The Higgs boson is required to be produced in association with a Z boson, and the Z boson is required to decay to either electrons or muons with the Higgs boson decaying to a b (b) over bar pair. The data are well described by the expected background, leading to 95% confidence level cross section upper limits sigma (p (p) over bar -> ZH) x B(H -> b (b) over bar) in the range of 3.1 pb to 4.4 pb.
|
|
| 43. |
- Abazov, V. M., et al.
(author)
-
Search for a scalar or vector particle decaying into Z gamma in p(p)over-bar collisions at root s=1.96 TeV
- 2009
-
In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 671:3, s. 349-355
-
Journal article (peer-reviewed)abstract
- We present a search for a narrow scalar or vector resonance decaying into Z gamma with a subsequent Z boson decay into a pair of electrons or moons. The data for this search were collected with the D circle divide detecror at the Fermilab Tevatron p (p) over bar collider at a center of mass energy root s = 1.96 TeV. Using 1.1 (1.0) fb(-1) of data, we observe 49 (50) candidate events in the electron (muon) channel, in good agreement with the standard model prediction. From the combination of both channels, we derive 95% C.L. upper limits on the cross section times branching fraction (sigma x B) into Z gamma. These limits range from 0.19 (0.20) pb for a scalar (vector) resonance mass of 600 GeV/c(2) to 2.5 (3.1) pb for a mass of 140 GeV/c(2).
|
|
| 44. |
- Abazov, V. M., et al.
(author)
-
Search for B0s → μ+μ− decays at D0
- 2007
-
In: Physical Review D. - : American Physical Society. - 1550-7998 .- 1550-2368. ; 76:9
-
Journal article (peer-reviewed)abstract
- We report results from a search for the decay B0s → μ+μ− using 1.3 fb−1 of p¯p collisions at √s=1.96 TeV collected by the D0 experiment at the Fermilab Tevatron Collider. We find two candidate events, consistent with the expected background of 1.24±0.99, and set an upper limit on the branching fraction of B(B0s → μ+μ−)<1.2×10−7 at the 95% C.L.
|
|
| 45. |
- Abazov, V. M., et al.
(author)
-
Search for decay of a fermiophobic Higgs boson h(f) -> gamma gamma with the D0 detector at root s=1.96 TeV
- 2008
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 101:5, s. 051801-:101, s. 051801-
-
Journal article (peer-reviewed)abstract
- We report the results of a search for a narrow resonance decaying into two photons in 1.1 fb(-1) of data collected by the D0 experiment at the Fermilab Tevatron Collider during the period 2002-2006. We find no evidence for such a resonance and set a lower limit on the mass of a fermiophobic Higgs boson of m(hf) > 100 GeV at the 95% C.L. This exclusion limit exceeds those obtained in previous searches at the Fermilab Tevatron and covers a significant region of the parameter space B(h(f) -> gamma gamma) vs m(hf) which was not accessible at the CERN Large Electron-Positron Collider.
|
|
| 46. |
- Abazov, V. M., et al.
(author)
-
Search for excited electrons in p(p)over-bar collisions at root s=1.96 TeV
- 2008
-
In: Physical Review D. - 1550-7998 .- 1550-2368. ; D:77, s. 091102-
-
Journal article (peer-reviewed)abstract
- We present the results of a search for the production of an excited state of the electron, e(*), in proton-antiproton collisions at root s = 1.96 TeV. The data were collected with the D0 experiment at the Fermilab Tevatron Collider and correspond to an integrated luminosity of approximately 1 fb(-1). We search for e(*) in the process p (p) over bar -> e(*)e, with the e(*) subsequently decaying to an electron plus photon. No excess above the standard model background is observed. Interpreting our data in the context of a model that describes e(*) production by four-fermion contact interactions and e(*) decay via electroweak processes, we set 95% C.L. upper limits on the production cross section ranging from 8.9 to 27 fb, depending on the mass of the excited electron. Choosing the scale for contact interactions to be Lambda = 1 TeV, excited electron masses below 756 GeV are excluded at the 95% C.L.
|
|
| 47. |
- Abazov, V. M., et al.
(author)
-
Search for flavor-changing-neutral-current D meson decays
- 2008
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 100:10, s. 101801-:100, s. 101801-
-
Journal article (peer-reviewed)abstract
- We study the flavor-changing-neutral-current process c -> u mu(+)mu(-) using 1.3 fb(-1) of p (p) over bar collisions at root s = 1.96 TeV recorded by the D0 detector operating at the Fermilab Tevatron Collider. We see clear indications of the charged-current mediated D-s(+) and D+->phi pi(+)->mu(+)mu(-)pi(+) final states with significance greater than 4 standard deviations above background for the D+ state. We search for the continuum neutral-current decay of D+->pi(+)mu(+)mu(-) in the dimuon invariant mass spectrum away from the phi resonance. We see no evidence of signal above background and set a limit of B(D+->pi(+)mu(+)mu(-))< 3.9 x 10(-6) at the 90% C.L. This limit places the most stringent constraint on new phenomena in the c -> u mu(+)mu(-) transition.
|
|
| 48. |
- Abazov, V. M., et al.
(author)
-
Search for Higgs bosons decaying to tau pairs in p(p)over-bar collisions with the D0 detector
- 2008
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 101:7, s. 071804-:101, s. 071804-
-
Journal article (peer-reviewed)abstract
- We present a search for the production of neutral Higgs bosons phi decaying into tau(+)tau(-) final states in p (p) over bar collisions at a center-of-mass energy of 1.96 TeV. The data, corresponding to an integrated luminosity of approximately 1 fb(-1), were collected by the D0 experiment at the Fermilab Tevatron Collider. Limits on the production cross section times branching ratio are set. The results are interpreted in the minimal supersymmetric standard model yielding limits that are the most stringent to date at hadron colliders.
|
|
| 49. |
- Abazov, V. M., et al.
(author)
-
Search for large extra dimensions via single photon plus missing energy final states at root s=1.96 TeV
- 2008
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 101:1, s. 011601-:101, s. 011601-
-
Journal article (peer-reviewed)abstract
- We report on a search for large extra dimensions in a data sample of approximately 1 fb(-1) of p (p) over bar collisions at root s=1.96 TeV. We investigate Kaluza-Klein graviton production with a photon and missing transverse energy in the final state. At the 95% C.L. we set limits on the fundamental mass scale M-D from 884 to 778 GeV for two to eight extra dimensions.
|
|
| 50. |
- Abazov, V. M., et al.
(author)
-
Search for pair production of doubly charged Higgs bosons in the H++H--->mu(+)mu(+)mu(-)mu(-) final state
- 2008
-
In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 101:7, s. 071803-:101, s. 071803-
-
Journal article (peer-reviewed)abstract
- We report the results of a search for pair production of doubly charged Higgs bosons via p (p) over bar -> H++H--X ->mu(+)mu(+)mu(-)mu X- at root s=1.96 TeV. We use a data set corresponding to an integrated luminosity of 1.1 fb(-1) collected from 2002 to 2006 by the D0 detector at the Fermilab Tevatron Collider. In the absence of an excess above the standard model background, lower mass limits of M(H-L(+/-+/-))> 150 GeV/c(2) and M(H-R(+/-+/-))> 127 GeV/c(2) at 95% C.L. are set, respectively, for left-handed and right-handed doubly charged Higgs bosons assuming a 100% branching ratio into muons.
|
|
