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- Bravo, L, et al.
(author)
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- 2021
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swepub:Mat__t
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- Thomas, HS, et al.
(author)
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- 2019
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- Tabiri, S, et al.
(author)
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- 2021
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- Glasbey, JC, et al.
(author)
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- 2021
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- 2019
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Journal article (peer-reviewed)
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- Fabian, ID, et al.
(author)
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Travel burden and clinical presentation of retinoblastoma: analysis of 1024 patients from 43 African countries and 518 patients from 40 European countries
- 2021
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In: The British journal of ophthalmology. - : BMJ. - 1468-2079 .- 0007-1161. ; 105:10, s. 1435-1443
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Journal article (peer-reviewed)abstract
- The travel distance from home to a treatment centre, which may impact the stage at diagnosis, has not been investigated for retinoblastoma, the most common childhood eye cancer. We aimed to investigate the travel burden and its impact on clinical presentation in a large sample of patients with retinoblastoma from Africa and Europe.MethodsA cross-sectional analysis including 518 treatment-naïve patients with retinoblastoma residing in 40 European countries and 1024 treatment-naïve patients with retinoblastoma residing in 43 African countries.ResultsCapture rate was 42.2% of expected patients from Africa and 108.8% from Europe. African patients were older (95% CI −12.4 to −5.4, p<0.001), had fewer cases of familial retinoblastoma (95% CI 2.0 to 5.3, p<0.001) and presented with more advanced disease (95% CI 6.0 to 9.8, p<0.001); 43.4% and 15.4% of Africans had extraocular retinoblastoma and distant metastasis at the time of diagnosis, respectively, compared to 2.9% and 1.0% of the Europeans. To reach a retinoblastoma centre, European patients travelled 421.8 km compared to Africans who travelled 185.7 km (p<0.001). On regression analysis, lower-national income level, African residence and older age (p<0.001), but not travel distance (p=0.19), were risk factors for advanced disease.ConclusionsFewer than half the expected number of patients with retinoblastoma presented to African referral centres in 2017, suggesting poor awareness or other barriers to access. Despite the relatively shorter distance travelled by African patients, they presented with later-stage disease. Health education about retinoblastoma is needed for carers and health workers in Africa in order to increase capture rate and promote early referral.
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| 13. |
- Ademuyiwa, Adesoji O., et al.
(author)
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Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries
- 2016
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In: BMJ Global Health. - : BMJ Publishing Group Ltd. - 2059-7908. ; 1:4
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Journal article (peer-reviewed)abstract
- Background: Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery in children is patchy in resource-poor regions. This study was aimed to determine the mortality risk for emergency abdominal paediatric surgery in low-income countries globally.Methods: Multicentre, international, prospective, cohort study. Self-selected surgical units performing emergency abdominal surgery submitted prespecified data for consecutive children aged <16 years during a 2-week period between July and December 2014. The United Nation's Human Development Index (HDI) was used to stratify countries. The main outcome measure was 30-day postoperative mortality, analysed by multilevel logistic regression.Results: This study included 1409 patients from 253 centres in 43 countries; 282 children were under 2 years of age. Among them, 265 (18.8%) were from low-HDI, 450 (31.9%) from middle-HDI and 694 (49.3%) from high-HDI countries. The most common operations performed were appendectomy, small bowel resection, pyloromyotomy and correction of intussusception. After adjustment for patient and hospital risk factors, child mortality at 30 days was significantly higher in low-HDI (adjusted OR 7.14 (95% CI 2.52 to 20.23), p<0.001) and middle-HDI (4.42 (1.44 to 13.56), p=0.009) countries compared with high-HDI countries, translating to 40 excess deaths per 1000 procedures performed.Conclusions: Adjusted mortality in children following emergency abdominal surgery may be as high as 7 times greater in low-HDI and middle-HDI countries compared with high-HDI countries. Effective provision of emergency essential surgery should be a key priority for global child health agendas.
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- Omokungbe, Opeyemi R., et al.
(author)
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Analysis of the variability of airborne particulate matter with prevailing meteorological conditions across a semi -urban environment using a network of low-cost air quality sensors
- 2020
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In: Heliyon. - : Elsevier BV. - 2405-8440. ; 6:6
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Journal article (peer-reviewed)abstract
- The concentrations of fine and coarse fractions of airborne particulate matter (PM) and meteorological variables (wind speed, wind direction, temperature and relative humidity) were measured at six selected locations in Ile Ife, a prominent university town in Nigeria using a network of low-cost air quality (AQ) sensor units. The objective of the deployment was to collate baseline air quality data and assess the impact of prevailing meteorological con- ditions on PM concentrations in selected residential communities downwind of an iron smelting facility. The raw data obtained from OPC-N2 of the AQ sensor units was corrected using the RH correction factor developed based k -Kohler theory. This PM (corrected) fast time resolution data (20 s) from the AQ sensor units were used to create daily averages. The overall mean mass concentrations for PM2.5 and PM10 were 213.3, 44.1, 23.8, 27.7, 20.2 and 41.5 mu g/m(3) and; 439.9, 107.1, 55.0, 72.4, 45.5 and 112.0 mu g/m(3) for Fasina (Iron -Steel Smelting Factory, ISSF), Modomo, Eleweran, Fire Service, O.A.U. staff quarters and Obafemi Awolowo University Teaching and Research Farm (OAUTRF), respectively. PM concentration and wind speed showed a negative exponential distribution curve with the lowest exponential fi t coef ficient of determination (R-2) values of 0.08 for PM2.5 and 0.03 for PM10 during nighttime periods at Eleweran and Fire service sites, respectively. The relationship between PM concen- tration and temperature gave a decay curve indicating that higher PM concentrations were observed at lower temperatures. The exponential distribution curve for the relationship between PM concentration and relative humidity (RH) showed that PM concentrations do not vary for RH 80 % while stronger relationship was noticed with higher PM concentration for RH 80 % for both day and nighttime. The performances of the MLR model were slightly poor and as such not too reliable for predicting the concentration but useful for improving predictive model accuracy when other variables contributing to the variability of PM is considered. The study concluded that the anthropogenic and industrial activities at the smelting factory contribute signi ficantly to the elevated PM mass concentration measured at the study locations.
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- Imran, Muhammad A., et al.
(author)
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Exploring the Boundaries of Connected Systems: Communications for Hard-to-Reach Areas and Extreme Conditions
- 2024
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In: Proceedings of the IEEE. - : Institute of Electrical and Electronics Engineers (IEEE). - 0018-9219 .- 1558-2256.
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Journal article (peer-reviewed)abstract
- Cellular communication standards have been established to ensure connectivity across most urban environments, complemented by deployment hardware and facilities tailored for city life. At the same time, numerous initiatives seek to broaden connectivity to rural and developing areas. However, with nearly half the global population still offline, there is an urgent need to drive research toward enhancing connectivity in areas and conditions that deviate from the norm. This article delves into innovative communication solutions not only for hard-to-reach and extreme environments but also introduces “hard-to-serve” areas as a crucial, yet underexplored, category within the broader spectrum of connectivity challenges.We explore the latest advancements in communication systems designed for environments subject to extreme temperatures, harsh weather, excessive dust, or even disasters such as fires. Our exploration spans the entire communication stack, covering communications on isolated islands, sparsely populated regions, mountainous terrains, and even underwater and underground settings. We highlight system architectures, hardware, materials, algorithms, and other pivotal technologies that promise to connect these challenging areas. Through case studies, we explore the application of 5G for innovative research, long range (LoRa) for audio messages and emails, LoRa wireless connections, free-space optics, communications in underwater and underground scenarios, delay-tolerant networks, satellite links, and the strategic use of shared spectrum and TV white space (TVWS) to improve mobile connectivity in secluded and remote regions. These studies also touch on prevalent challenges such as power outages, regulatory gaps, technological availability, and human resource constraints, where we introduce the concept of peri-urban hard-to-serve areas where populations might struggle with affordability or lack the skills for traditional connectivity solutions. This article provides an exhaustive summary of our research, showcasing how 6G and future networks will play a crucial role in delivering connectivity to areas that are hard-to-reach, hard-to-serve, or subject to extreme conditions (ECs).
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| 19. |
- Oguntuase, James, et al.
(author)
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Refined multidimensional Hardy-type inequalities via superquadracity
- 2008
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In: Banach Journal of Mathematical Analysis. - : Springer Science and Business Media LLC. - 1735-8787. ; 2:2, s. 129-139
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Journal article (peer-reviewed)abstract
- Some new refined multidimensional Hardy-type inequalities for p 2 and their duals are derived and discussed. Moreover, these inequalities hold in the reversed direction when 1 < p 2. The results obtained are based mainly on some new results for superquadratic and subquadratic functions. In particular, our results further extend the recent results in [J.A. Oguntuase and L.-E. Persson, Refinement of Hardy's inequalities via superquadratic and subquadratic functions, J
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