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- Kirişli, Hortense, et al.
(author)
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Standardized evaluation framework for evaluating coronary artery stenosis detection, stenosis quantification and lumen segmentation algorithms in computed tomography angiography
- 2013
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In: Medical Image Analysis. - : Elsevier. - 1361-8415 .- 1361-8423. ; 17:8, s. 859-876
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Journal article (peer-reviewed)abstract
- Though conventional coronary angiography (CCA) has been the standard of reference for diagnosing coronary artery disease in the past decades, computed tomography angiography (CIA) has rapidly emerged, and is nowadays widely used in clinical practice. Here, we introduce a standardized evaluation framework to reliably evaluate and compare the performance of the algorithms devised to detect and quantify the coronary artery stenoses, and to segment the coronary artery lumen in CIA data. The objective of this evaluation framework is to demonstrate the feasibility of dedicated algorithms to: (I) (semi-)automatically detect and quantify stenosis on CIA, in comparison with quantitative coronary angiography (QCA) and CIA consensus reading, and (2) (semi-)automatically segment the coronary lumen on CIA, in comparison with expert's manual annotation. A database consisting of 48 multicenter multivendor cardiac CIA datasets with corresponding reference standards are described and made available. The algorithms from 11 research groups were quantitatively evaluated and compared. The results show that (1) some of the current stenosis detection/quantification algorithms may be used for triage or as a second-reader in clinical practice, and that (2) automatic lumen segmentation is possible with a precision similar to that obtained by experts. The framework is open for new submissions through the website, at http://coronary.bigr.nl/stenoses/.
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| 2. |
- Sparovek, Gerd, 1962, et al.
(author)
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Sustainable bioproducts in Brazil: disputes and agreements on a common ground agenda for agriculture and nature protection
- 2016
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In: Biofuels, Bioproducts and Biorefining. - : Wiley. - 1932-1031 .- 1932-104X. ; 10:3, s. 204-221
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Journal article (peer-reviewed)abstract
- A key question for food, biofuels, and bioproducts production is how agriculture affects the environment, and social and economic development. In Brazil, a large agricultural producer and among the biologically wealthiest of nations, this question is challenging and opinions often clash. The Brazilian parliament and several stakeholders have recently debated the revision of the Forest Act, the most important legal framework for conservation of natural vegetation on Brazilian private agricultural lands. Past decades have shown improvements in the agricultural sector with respect to productivity and efficiency, along with great reductions in deforestation and growth of environmentally certified production. However, the opposing sides in the debate have ignored this progress and instead continue to entrench their respective combative positions. A structured exchange involving nine experts associated with major producer interests (livestock, crops, planted forest, and charcoal) and environmental NGOs was moderated based on a framework that sorted viewpoints into four categories: (i) common ground - compatible interests considered to be high priority for Brazilian sustainable agricultural development; (ii) serving exclusive nature conservation interest; (iii) serving exclusive agricultural production interest; and (iv) mainly serving the purpose of sustaining dispute. We conclude that the majority of actions and expected future trends reflect achievements and ambitions to balance production and conservation, but much public opinion - and in turn decisions in the parliament and government for agriculture and conservation - is shaped by a perceived conflict between these objectives and a debate that has become, at least to some extent, an end in itself.
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