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- Semb, G, et al.
(author)
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Erratum
- 2017
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In: Journal of plastic surgery and hand surgery. - 2000-6764. ; 51:2, s. 158-158
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Journal article (peer-reviewed)
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- Nguyen, Thanh N, et al.
(author)
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Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: A 1-Year Follow-up.
- 2023
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In: Neurology. - 1526-632X. ; 100:4
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Journal article (peer-reviewed)abstract
- Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), IVT, and mechanical thrombectomy over a 1-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020).We conducted a longitudinal retrospective study across 6 continents, 56 countries, and 275 stroke centers. We collected volume data for COVID-19 admissions and 4 stroke metrics: ischemic stroke admissions, ICH admissions, IVT treatments, and mechanical thrombectomy procedures. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases.There were 148,895 stroke admissions in the 1 year immediately before compared with 138,453 admissions during the 1-year pandemic, representing a 7% decline (95% CI [95% CI 7.1-6.9]; p < 0.0001). ICH volumes declined from 29,585 to 28,156 (4.8% [5.1-4.6]; p < 0.0001) and IVT volume from 24,584 to 23,077 (6.1% [6.4-5.8]; p < 0.0001). Larger declines were observed at high-volume compared with low-volume centers (all p < 0.0001). There was no significant change in mechanical thrombectomy volumes (0.7% [0.6-0.9]; p = 0.49). Stroke was diagnosed in 1.3% [1.31-1.38] of 406,792 COVID-19 hospitalizations. SARS-CoV-2 infection was present in 2.9% ([2.82-2.97], 5,656/195,539) of all stroke hospitalizations.There was a global decline and shift to lower-volume centers of stroke admission volumes, ICH volumes, and IVT volumes during the 1st year of the COVID-19 pandemic compared with the prior year. Mechanical thrombectomy volumes were preserved. These results suggest preservation in the stroke care of higher severity of disease through the first pandemic year.This study is registered under NCT04934020.
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- Ellefsen, S., et al.
(author)
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Blood flow-restricted strength training displays high functional and biological efficacy in women: a within-subject comparison with high-load strength training
- 2015
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In: American Journal of Physiology-Regulatory Integrative and Comparative Physiology. - : American Physiological Society. - 0363-6119 .- 1522-1490. ; 309:7
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Journal article (peer-reviewed)abstract
- Limited data exist on the efficacy of low-load blood flow-restricted strength training (BFR), as compared directly to heavy-load strength training (HST). Here, we show that 12 wk of twice-a-week unilateral BFR [30% of one repetition maximum (1RM) to exhaustion] and HST (6-10RM) of knee extensors provide similar increases in 1RM knee extension and cross-sectional area of distal parts of musculus quadriceps femoris in nine untrained women (age 22 +/- 1 yr). The two protocols resulted in similar acute increases in serum levels of human growth hormone. On the cellular level, 12 wk of BFR and HST resulted in similar shifts in muscle fiber composition in musculus vastus lateralis, evident as increased MyHC2A proportions and decreased MyHC2X proportions. They also resulted in similar changes of the expression of 29 genes involved in skeletal muscle function, measured both in a rested state following 12 wk of training and subsequent to singular training sessions. Training had no effect on myonuclei proportions. Of particular interest, 1) gross adaptations to BFR and HST were greater in individuals with higher proportions of type 2 fibers, 2) both BFR and HST resulted in approximately four-fold increases in the expression of the novel exercise-responsive gene Syndecan-4, and 3) BFR provided lesser hypertrophy than HST in the proximal half of musculus quadriceps femoris and also in CSA(peak), potentially being a consequence of pressure from the tourniquet utilized to achieve blood flow restriction. In conclusion, BFR and HST of knee extensors resulted in similar adaptations in functional, physiological, and cell biological parameters in untrained women.
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- Obel, C, et al.
(author)
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The strengths and difficulties questionnaire in the Nordic countries
- 2004
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In: European Child Adolescent Psychiatry. ; 13:suppl 2, s. 1132-9
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Journal article (peer-reviewed)abstract
- BACKGROUND: The Strengths and Difficulties Questionnaire (SDQ) has been translated into the different Nordic languages between 1996 and 2003. During the past few years, SDQs have been completed for nearly 100,000 children and adolescents in population-based studies as well as in clinical samples. The largest studies have been performed in Norway and Denmark, and in these countries the diagnostic interview DAWBA has also been used in conjunction with the SDQ. AIMS: In addition to a brief overview of past and ongoing SDQ work in Sweden, Finland, Norway, Denmark, and Iceland, we present scale means and standard deviations from selected community studies with comparable age groups, including parental reports for 7, 9 and 11 year-old children and self-reports of 13 and 15 year-olds. CONCLUSIONS: The descriptive statistics suggest that the distributions of SDQ scores are very similar across the Nordic countries. Further collaborative efforts in establishing norms and evaluating the validity of the SDQ as a screening instrument are encouraged.
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- Bye, E., et al.
(author)
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Quantitative Determination of Airborne Respirable Non-Fibrous alpha-Silicon Carbide by X-ray Powder Diffractometry
- 2009
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In: Annals of Occupational Hygiene. - : Oxford University Press (OUP). - 0003-4878 .- 1475-3162. ; 53:4, s. 403-408
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Journal article (peer-reviewed)abstract
- Objectives: The purpose of the present investigation was to establish a method for the determination of airborne respirable non-fibrous silicon carbide (SiC). The main application is within the industrial production of SiC. Methods: Due to the complex airborne aerosol mixture of crystalline compounds in the SiC industry, X-ray powder diffractometry was selected as the most appropriate method. Without any international standard material for the respirable fraction of non-fibrous SiC, pure and suitable products from three SiC plants in Norway were selected. These products have a median particle diameter in the range 4.4-5.1 mu m. The method is based on thin sample technique, with the dust deposited on a polycarbonate filter. Absorption correction is done by standard procedures with the use of a silver filter, situated below the polycarbonate filter. Results: The diffraction line used for quantitative determination was selected carefully. This was done to avoid interferences from quartz, cristobalite, and graphite, which all are airborne components present in the atmosphere during the industrial process. The instrumental limit of detection for the method is 12 mu g. Conclusions: This method has been used to determine airborne non-fibrous SiC in a comprehensive ongoing project in the Norwegian SiC industry for further epidemiological studies. The method is fully applicable for compliance work.
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- Crouzillat, D, et al.
(author)
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Theobroma cacao L : A genetic linkage map and quantitative trait loci analysis
- 1996
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In: Theoretical and Applied Genetics. - : SPRINGER. - 0040-5752 .- 1432-2242. ; 93:1-2, s. 205-214
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Journal article (peer-reviewed)abstract
- A genetic linkage map of Theobroma cacao (cocoa) has been constructed from 131 backcross trees derived from a cross between a single tree of the variety Catongo and an F1 tree from the cross of Catongo by Pound 12. The map comprises 138 markers: 104 RAPD loci, 32 RFLP loci and two morphologic loci. Ten linkage groups were found which cover 1068 centimorgans (cM). Only six (4%) molecular-marker loci show a significant deviation from the expected 1:1 segregation ratio. The average distance between two adjacent markers is 8.3 cM. The final genome-size estimates based on two-point linkage data ranged from 1078 to 1112 cM for the cocoa genome. This backcross progeny segregates for two apparently single gene loci controlling (1) anthocyanidin synthesis (Anth) in seeds, leaves and flowers and (2) self-compatibility (Autoc). The Anth locus was found to be 25 cM from Autoc and two molecular markers co-segregate with Anth. The genetic linkage map was used to localize QTLs for early flowering, trunk diameter, jorquette height and ovule number in the BC1 generation using both single-point ANOVA and interval mapping. A minimum number of 2-4 QTLs (P<0.01) involved in the genetic expression of the traits studied was detected. Coincident map locations of a QTL for jorquette height and trunk diameter suggests the possibility of pleiotropic effects in cocoa for these traits. The combined estimated effects of the different mapped QTLs explained between 11.2% and 25.8% of the phenotypic variance observed in the BC1 population.
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- Ozawa, TO, et al.
(author)
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A new yardstick for rating dental arch relationship in patients with complete bilateral cleft lip and palate
- 2011
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In: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association. - : SAGE Publications. - 1545-1569. ; 48:2, s. 167-172
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Journal article (peer-reviewed)abstract
- To develop yardsticks for assessment of dental arch relationship in young individuals with repaired complete bilateral cleft lip and palate appropriate to different stages of dental development. Participants Eleven cleft team orthodontists from five countries worked on the projects for 4 days. A total of 776 sets of standardized plaster models from 411 patients with operated complete bilateral cleft lip and palate were available for the exercise. Statistics The interexaminer reliability was calculated using weighted kappa statistics. Results The interrater weighted kappa scores were between .74 and .92, which is in the “good” to “very good” categories. Conclusions Three bilateral cleft lip and palate yardsticks for different developmental stages of the dentition were made: one for the deciduous dentition (6-year-olds’ yardstick), one for early mixed dentition (9-year-olds’ yardstick), and one for early permanent dentition (12-year-olds’ yardstick).
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- Rytter, Erling, et al.
(author)
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Hydrophobic catalyst support surfaces by silylation of gamma-alumina for Co/Re Fischer-Tropsch synthesis
- 2018
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In: Catalysis Today. - : Elsevier. - 0920-5861 .- 1873-4308. ; 299, s. 20-27
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Journal article (peer-reviewed)abstract
- Eight different silanes with chloro or methoxy active ligands have been examined to modify the surface of a standard.-alumina support to investigate the effect of surface acidity and hydrophobicity in Fischer-Tropsch synthesis (FTS) at common operating conditions (210 degrees C; 20 bar; H-2/CO = 2.1). Silanes were impregnated prior to cobalt (Pre) or after cobalt impregnation and calcination (Post). Samples were characterized by standard techniques (FTIR, XRD, TPD, TPR, TGA, BET). In the Post series, cobalt crystallite size is maintained, while it is reduced when cobalt impregnation is performed on a partly hydrophobic surface. Both series of catalysts have FTS performances that deviate significantly from a reference catalyst and, in combination with characterization data, the silanes have modified all the 15 examined catalysts. The Pre series offer options for improved selectivity to higher hydrocarbons in FTS. The effects of silylation on FT performance mechanisms are discussed in terms of gas diffusion limitations, strain in cobalt particles and partial blocking of CO activation sites.
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- Silva, C. N. S., et al.
(author)
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Insights into the genetic architecture of morphological traits in two passerine bird species
- 2017
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In: Heredity. - : Springer Science and Business Media LLC. - 0018-067X .- 1365-2540. ; 119:3, s. 197-205
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Journal article (peer-reviewed)abstract
- Knowledge about the underlying genetic architecture of phenotypic traits is needed to understand and predict evolutionary dynamics. The number of causal loci, magnitude of the effects and location in the genome are, however, still largely unknown. Here, we use genome-wide single-nucleotide polymorphism (SNP) data from two large-scale data sets on house sparrows and collared flycatchers to examine the genetic architecture of different morphological traits (tarsus length, wing length, body mass, bill depth, bill length, total and visible badge size and white wing patches). Genomic heritabilities were estimated using relatedness calculated from SNPs. The proportion of variance captured by the SNPs (SNP-based heritability) was lower in house sparrows compared with collared flycatchers, as expected given marker density (6348 SNPs in house sparrows versus 38 689 SNPs in collared flycatchers). Indeed, after downsampling to similar SNP density and sample size, this estimate was no longer markedly different between species. Chromosome-partitioning analyses demonstrated that the proportion of variance explained by each chromosome was significantly positively related to the chromosome size for some traits and, generally, that larger chromosomes tended to explain proportionally more variation than smaller chromosomes. Finally, we found two genome-wide significant associations with very small-effect sizes. One SNP on chromosome 20 was associated with bill length in house sparrows and explained 1.2% of phenotypic variation (V-P), and one SNP on chromosome 4 was associated with tarsus length in collared flycatchers (3% of V-P). Although we cannot exclude the possibility of undetected large-effect loci, our results indicate a polygenic basis for morphological traits.
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- Stenset, Nina Emilie, et al.
(author)
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Seasonal and annual variation in the diet of brown bears Ursus arctos in the boreal forest of southcentral Sweden
- 2016
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In: Wildlife Biology. - : Wiley. - 0909-6396 .- 1903-220X. ; 22:3, s. 107-116
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Journal article (peer-reviewed)abstract
- Understanding a species' feeding ecology is essential for successful management and conservation, because food abundance can influence body mass, survival, reproductive success, movements, and habitat use. We describe annual and seasonal variations in the diet of brown bears Ursus arctos in southcentral Sweden, based on analysis of 527 fecal samples from 1994-1996 and 2000-2001. There was distinct seasonal variation in most of the 26 food items we documented. Ungulates, predominantly moose Alces alces, and insects comprised most of the estimated dietary energy content in spring and summer. Insects were represented almost entirely by ants, of which Formica spp. and Camponotus herculeanus were the most common. During autumn, berries dominated the diet. The most important berry species were bilberry Vaccinium myrtillus, crowberry Empetrum hermaphoditum and lingonberry V. vitis-idaea. We determined berry availability by inventorying 308 random plots three times for two consecutive years. These three berries occurred with great spatial, seasonal and annual variation in abundance. The bears showed the strongest positive preference for bilberries, a lesser positive preference for crowberries, but no preference for lingonberries. The proportion of berries in the autmn diet was stable between years, but the relative importance of the species changed, indicating that bears switched to crowberries when bilberries were less abundant. The effects of predicted future climatic change might have severe effects on the availability of the berries, which is the only important food available for fat acquisition prior to hibernation.
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