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1.
  • Forsman, Mikael, Professor, et al. (author)
  • Systematic risk management with RAMP for riskassessment and adapted changes - an implementation study
  • 2022
  • In: NES2022 WORK WELL Conference Proceedings Research. ; , s. 156-157
  • Conference paper (peer-reviewed)abstract
    • RAMP (Risk Assessment and Management tool for manual handling – Proactively), is arisk management tool focusing on manual handling work. Since 2017 RAMP has beenspread to over 105 countries. More than other methods, RAMP supports the entire riskmanagement process. RAMP is based on risk factors documented in scientific literature,and it has been evaluated regarding usability and reliability. It is now used for MSDrisk management in many organisations. The feedback from RAMP users is positive,and there are indications of reductions in sick absence.The purpose of the ongoing project is to investigate a selection of effects thatimplementation entails and to examine the implementation of RAMP from a leadershipand system perspective. Specific questions are: What happens when a companyimplements RAMP? Are the risk factors reduced? What affects the change? Whatstrategies do companies use when implementing RAMP? Are the effects of whichstrategies companies apply when implementing affected? What are the facilitators andbarriers to the implementation of this risk management method?The project is carried out as an implementation study based on mixed methods incollaboration between researchers and four production companies and two FHV actors.The effects and implementation of RAMP will be evaluated by comparing risk levels,qualitative interviews, document analyses, questionnaires and structured observationsof work processes. For changes in risk factors, RAMP risk assessments, which includeobservations and objectivemeasurements of push-pull forces, carried out at baseline andat follow-up will be compared. If possible, in addition to the above data collection, thecompany's own data on sick leave, productivity and quality (eg quality deficiency data)will be included and monitored over time.Implementations and effects of RAMP will be summarized in so-called logicalmodels. These models will identify inputs (e.g. time and resources set aside forimplementation), activities (e.g. training and measures implemented), intermediate(short-term) outcomes (e.g. the extent to which RAMP is used in the systematic workenvironment work and in the entire process for risk management, how much of the highrisks have been reduced, what type of measures have been taken and how the riskawareness has developed among employees), long-term outcomes (e.g. employees'perception of the workload, perceived health and perceived problems), and possiblylong-term outcomes (e.g. changes in sick absence, quality and productivity as well assharing good examples within the organisation).157At this point in the project, the questionnaire has been designed, companies havebeen contacted, and data collection at the first company, that now has assigned animplementation strategy, is about to start.The project is expected to show what effects on the work environment (possibly alsohealth, quality and productivity) that systematic application of the RAMP method canhave, aswell aswhich of the studied factors affect the implementation and to what extentthey do so. The results are expected to lead to new knowledge in the area of systematicrisk management and implementation strategies.
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2.
  • Rose, Linda M, 1963-, et al. (author)
  • RAMP -  A new tool for MSD risk management in manualhandling
  • 2017
  • In: Conference Proceedings 48th Annual Conference of the Association of Canadian Ergonomists  & 12th International Symposium on Human Factors in Organizational Design and Management "Organizing for High Performance ".
  • Conference paper (peer-reviewed)abstract
    • Summative Statement: In this conference contribution RAMP (Risk Assessment and Management tool for Manual Handling - Proactively) will be presented. It is developed for managing MSD risks in manual handling jobs. The presentation will include a demonstration of the digitalised tool and information about upcoming Massive Open Online Courses about it.Problem statement: Manual handling work is regarded as one of the main causes to increased risks of developing Musculoskeletal disorders (MSDs). Several MSD risk assessment tools have been developed, but have been found to have insufficiencies in managing MSD risks in manual handling. The insufficiencies include that tools only assess certain body parts or certain types of work, are not freely accessible, assess exposure but not risks, and don´t support the whole risk management process. In 2009 there was a call from a global company, which had identified a need for a scientifically based, freely accessible, risk assessment and risk management tool. The tool should support systematic risk management of MSD risks in manual handling jobs and be able to be used by companies themselves. To meet this call the development of the RAMP tool (Risk Assessment and Management tool for Manual Handling – Proactively) was started. It has been developed in a research and development (R&D) project in close co-operation between researchers and practitioners at companies.Research Objective: The objective of this conference contribution is to present the results of a seven year long R&D project: to describe the RAMP tool and its development, present the digitalised version, share some experiences from its use, and inform about upcoming RAMP Massive Open Online Courses (MOOCs), aimed at educating and training users in the RAMP tool.Methodology: RAMP is scientifically based and was developed with a participative R&D methodology. The participating organisations as well as the methodology, including the base for the development, ranging from scientific publications and legislation to user testing and feed-back, will be described in the presentation.Results: The RAMP tool consists of four parts: RAMP I, RAMP II, The Results module and the Action module. At the conference, these will be presented and the digitalised version of RAMP will be demonstrated. In addition, information about three Massive Open Online Courses (MOOCs) about the RAMP tool which are being developed will be presented and user experiences from applying RAMP will be shared. In addition to the oral presentation a workshop on RAMP is planned to be held at the conference.Discussion: The discussion focuses on how methods like RAMP, which are freely accessible, can be spread after the R&D project is finished. Another question is how to secure updates in the future for methods which do not bring any profit for the developers/owners.Conclusions: It is concluded that RAMP, a scientifically based new tool for risk management of MSD risks in manual handling, is freely available via KTH’s homepage and that a MOOC-package for disseminating knowledge and training on how to use the tool will be accessible from the autumn 2017.
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3.
  • Rose, Linda, 1963-, et al. (author)
  • The RAMP package for MSD risk management in manual handling – A freely accessible tool, with website and training courses
  • 2020
  • In: Applied Ergonomics. - : Elsevier BV. - 0003-6870 .- 1872-9126. ; 86
  • Journal article (peer-reviewed)abstract
    • In this paper the RAMP Package is presented with the objective to facilitate the application of the RAMP tool to systematically manage MSD risks. The package consists of the RAMP tool (Risk Assessment and Management tool for manual handling Proactively), the RAMP website, and free, globally available online, training courses (MOOCs). An Action module used for managing identified MSD risks is introduced. The tool, encompassing a wide range of risks, is applicable to the whole risk management process. Furthermore, RAMP is openly available for download, and free to use. The RAMP tool and training materials were developed using a participative iterative methodology including researchers and practitioners. RAMP was downloaded in 86 countries in the first 26 months since its' launch and over 2400 learners from high-, middle- and low-income countries have joined the MOOCs. The RAMP Package meets organisations’ needs for an accessible, comprehensive risk assessment and management tool.
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5.
  • Akselsson, Roland, et al. (author)
  • Safety and Risk
  • 2009
  • In: Work and technology on human terms. - 9789173650588 ; , s. 425-461
  • Book chapter (other academic/artistic)
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6.
  • Akselsson, Roland, et al. (author)
  • Säkerhet och risk
  • 2008
  • In: Arbete och teknik på människans villkor. - 9789173650373 ; , s. 425-461
  • Book chapter (other academic/artistic)
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7.
  • Arbete och teknik på människans villkor
  • 2015. - 3
  • Editorial collection (other academic/artistic)abstract
    • För att förstå samspelet mellan människor och mellan människor och teknik, krävs kunskaper inom flera olika områden. Boken inkluderar därför begrepp, kunskaper och metoder från bland annat psykologi, medicin, sociologi, fysik, kemi, ekonomi och juridik.Boken vänder sig främst till studerande inom arbetsvetenskap, ergonomi och liknande ämnesbenämningar på tekniska universitets- och högskoleutbildningar. Den passar också yrkesverksamma arbetsmiljöingenjörer, ergonomer och sjukgymnaster med flera.
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8.
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9.
  • Bergman, Åke, et al. (author)
  • A novel abbreviation standard for organobromine, organochlorine and organophosphorus flame retardants and some characteristics of the chemicals
  • 2012
  • In: Environment International. - : Elsevier BV. - 0160-4120 .- 1873-6750. ; 49, s. 57-82
  • Research review (peer-reviewed)abstract
    • Ever since the interest in organic environmental contaminants first emerged 50 years ago, there has been a need to present discussion of such chemicals and their transformation products using simple abbreviations so as to avoid the repetitive use of long chemical names. As the number of chemicals of concern has increased, the number of abbreviations has also increased dramatically, sometimes resulting in the use of different abbreviations for the same chemical. In this article, we propose abbreviations for flame retardants (FRs) substituted with bromine or chlorine atoms or including a functional group containing phosphorus, i.e. BFRs, CFRs and PFRs, respectively. Due to the large number of halogenated and organophosphorus FRs, it has become increasingly important to develop a strategy for abbreviating the chemical names of FRs. In this paper, a two step procedure is proposed for deriving practical abbreviations (PRABs) for the chemicals discussed. In the first step, structural abbreviations (STABs) are developed using specific STAB criteria based on the FR structure. However, since several of the derived STABs are complicated and long, we propose instead the use of PRABs. These are, commonly, an extract of the most essential part of the STAB, while also considering abbreviations previously used in the literature. We indicate how these can be used to develop an abbreviation that can be generally accepted by scientists and other professionals involved in FR related work. Tables with PRABs and STABs for BFRs, CFRs and PERs are presented, including CAS (Chemical Abstract Service) numbers, notes of abbreviations that have been used previously, CA (Chemical Abstract) name, common names and trade names, as well as some fundamental physicochemical constants.
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11.
  • Bohgard, Mats, et al. (author)
  • Chemical Health Risks
  • 2009
  • In: Work and Technology on Human Terms. - 9789173650588 ; , s. 307-337
  • Book chapter (other academic/artistic)
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12.
  • Bohgard, Mats, et al. (author)
  • Designing work and technology on human terms
  • 2009. - 1:1
  • In: Work and technology on human terms. - Stockholm : Prevent. - 9789173650588 ; , s. 9-18
  • Book chapter (pop. science, debate, etc.)
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13.
  • Bohgard, Mats, et al. (author)
  • Fysikaliska faktorer
  • 2008
  • In: Arbete och teknik på människans villkor. - 9789173650373 ; , s. 191-307
  • Book chapter (other academic/artistic)
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14.
  • Bohgard, Mats, et al. (author)
  • Kemiska hälsorisker
  • 2008
  • In: Arbete och teknik på människans villkor. - 9789173650373 ; , s. 309-337
  • Book chapter (pop. science, debate, etc.)
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15.
  • Bohgard, Mats, et al. (author)
  • Physical Factors
  • 2009
  • In: Work and Technology on Human Terms. - 9789173650588 ; , s. 191-306
  • Book chapter (other academic/artistic)
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16.
  • Butt, Salma, et al. (author)
  • The Target for Statins, HMG-CoA Reductase, Is Expressed in Ductal Carcinoma-In Situ and May Predict Patient Response to Radiotherapy.
  • 2014
  • In: Annals of Surgical Oncology. - : Springer Science and Business Media LLC. - 1534-4681 .- 1068-9265. ; 21:9, s. 2911-2919
  • Journal article (peer-reviewed)abstract
    • Patients with ductal carcinoma-in-situ (DCIS) are currently not prescribed adjuvant systemic treatment after surgery and radiotherapy. Prediction of DCIS patients who would benefit from radiotherapy is warranted. Statins have been suggested to exert radio-sensitizing effects. The target for cholesterol-lowering statins is HMG-CoA reductase (HMGCR), the rate-limiting enzyme in the mevalonate pathway. The aim of this study was to examine HMGCR expression in DCIS and study its treatment predictive value.
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17.
  • Cable, Jennifer, et al. (author)
  • Progress in vaccine development for infectious diseases : a Keystone Symposia report
  • 2023
  • In: Annals of the New York Academy of Sciences. - : John Wiley & Sons. - 0077-8923 .- 1749-6632. ; 1524:1, s. 65-86
  • Journal article (peer-reviewed)abstract
    • The COVID-19 pandemic has taught us many things, among the most important of which is that vaccines are one of the cornerstones of public health that help make modern longevity possible. While several different vaccines have been successful at stemming the morbidity and mortality associated with various infectious diseases, many pathogens/diseases remain recalcitrant to the development of effective vaccination. Recent advances in vaccine technology, immunology, structural biology, and other fields may yet yield insight that will address these diseases; they may also help improve societies' preparedness for future pandemics. On June 1-4, 2022, experts in vaccinology from academia, industry, and government convened for the Keystone symposium "Progress in Vaccine Development for Infectious Diseases" to discuss state-of-the-art technologies, recent advancements in understanding vaccine-mediated immunity, and new aspects of antigen design to aid vaccine effectiveness.
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18.
  • Carén, Helena, 1979, et al. (author)
  • High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors; Four cases of homozygous deletions of the CDKN2A gene.
  • 2008
  • In: BMC Genomics. - : Springer Science and Business Media LLC. - 1471-2164. ; 9:1
  • Journal article (peer-reviewed)abstract
    • Background Neuroblastoma is a very heterogeneous pediatric tumor of the sympathetic nervous system showing clinically significant patterns of genetic alterations. Favorable tumors usually have near-triploid karyotypes with few structural rearrangements. Aggressive stage 4 tumors often have near-diploid or near-tetraploid karyotypes and structural rearrangements. Whole genome approaches for analysis of genome-wide copy number have been used to analyze chromosomal abnormalities in tumor samples. We have used array-based copy number analysis using oligonucleotide single nucleotide polymorphisms (SNP) arrays to analyze the chromosomal structure of a large number of neuroblastoma tumors of different clinical and biological subsets. Results Ninety-two neuroblastoma tumors were analyzed with 50 K and/or 250 K SNP arrays from Affymetrix, using CNAG3.0 software. Thirty percent of the tumors harbored 1p deletion, 22% deletion of 11q, 26% had MYCN amplification and 45% 17q gain. Most of the tumors with 1p deletion were found among those with MYCN amplification. Loss of 11q was most commonly seen in tumors without MYCN amplification. In the case of MYCN amplification, two types were identified. One type displayed simple continuous amplicons; the other type harbored more complex rearrangements. MYCN was the only common gene in all cases with amplification. Complex amplification on chromosome 12 was detected in two tumors and three different overlapping regions of amplification were identified. Two regions with homozygous deletions, four cases with CDKN2A deletions in 9p and one case with deletion on 3p (the gene RBMS3) were also detected in the tumors. Conclusion SNP arrays provide useful tools for high-resolution characterization of significant chromosomal rearrangements in neuroblastoma tumors. The mapping arrays from Affymetrix provide both copy number and allele-specific information at a resolution of 10–12 kb. Chromosome 9p, especially the gene CDKN2A, is subject to homozygous (four cases) and heterozygous deletions (five cases) in neuroblastoma tumors.
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19.
  • Ekeberg, Tomas, 1983-, et al. (author)
  • Observation of a single protein by ultrafast X-ray diffraction
  • 2024
  • In: Light. - : Springer Nature. - 2095-5545 .- 2047-7538. ; 13:1
  • Journal article (peer-reviewed)abstract
    • The idea of using ultrashort X-ray pulses to obtain images of single proteins frozen in time has fascinated and inspired many. It was one of the arguments for building X-ray free-electron lasers. According to theory, the extremely intense pulses provide sufficient signal to dispense with using crystals as an amplifier, and the ultrashort pulse duration permits capturing the diffraction data before the sample inevitably explodes. This was first demonstrated on biological samples a decade ago on the giant mimivirus. Since then, a large collaboration has been pushing the limit of the smallest sample that can be imaged. The ability to capture snapshots on the timescale of atomic vibrations, while keeping the sample at room temperature, may allow probing the entire conformational phase space of macromolecules. Here we show the first observation of an X-ray diffraction pattern from a single protein, that of Escherichia coli GroEL which at 14 nm in diameter is the smallest biological sample ever imaged by X-rays, and demonstrate that the concept of diffraction before destruction extends to single proteins. From the pattern, it is possible to determine the approximate orientation of the protein. Our experiment demonstrates the feasibility of ultrafast imaging of single proteins, opening the way to single-molecule time-resolved studies on the femtosecond timescale.
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21.
  • Ellinor, Patrick T., et al. (author)
  • Meta-analysis identifies six new susceptibility loci for atrial fibrillation
  • 2012
  • In: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 44:6, s. 88-670
  • Journal article (peer-reviewed)abstract
    • Atrial fibrillation is a highly prevalent arrhythmia and a major risk factor for stroke, heart failure and death(1). We conducted a genome-wide association study (GWAS) in individuals of European ancestry, including 6,707 with and 52,426 without atrial fibrillation. Six new atrial fibrillation susceptibility loci were identified and replicated in an additional sample of individuals of European ancestry, including 5,381 subjects with and 10,030 subjects without atrial fibrillation (P < 5 x 10(-8)). Four of the loci identified in Europeans were further replicated in silico in a GWAS of Japanese individuals, including 843 individuals with and 3,350 individuals without atrial fibrillation. The identified loci implicate candidate genes that encode transcription factors related to cardiopulmonary development, cardiac-expressed ion channels and cell signaling molecules.
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22.
  • Franzon, Helena, et al. (author)
  • A usability study of the SRA Index (Sustainable Risk Awareness Index)- a KPI for Management Support
  • 2022
  • In: NES2022 WORK WELL Conference Proceedings. ; , s. 147-154
  • Conference paper (peer-reviewed)abstract
    • Companies use risk observations and work environment (WE) deviations such as occupationalaccidents and occupational illnesses to prevent injuries. There is no standard for how risks andoccupational injuries are reported. Praktikertjänst's management requests a standard as ameasure that can be used to work more proactively with health and safety and supportsustainable business development. Therefore, the SRA method was developed for calculatingand visualizing a work environment KPI related to the severity of WE deviations, the SRA Index.(Sustainable Risk Awareness Index for management support). Existing data (risk observations,near misses, work-related accidents and work-related illnesses) are used for calculating the SRAIndex. In this study the usability of the SRA Index was evaluated with a questionnaire amongwork environment experts. They assessed the SRA method to be easy to understand, to havehigh usability and to be valuable for assessing an organisation’s risk awareness.
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23.
  • Franzon, Helena, et al. (author)
  • The SRA Index (Sustainable Risk Awareness Index) : A New KPI for Management Support
  • 2021
  • In: Lecture Notes in Networks and Systems. - Cham : Springer Nature. ; , s. 457-466
  • Conference paper (peer-reviewed)abstract
    • The objective with this project is to develop a key performance indicator (KPI) related to work environment deviations, such as risk observations, near misses and injuries. This as a support for managers decision making in steering companies towards higher risk awareness as well as to contribute to the development of safer and more sustainable work environments and jobs. In addition, the aim is to contribute to a work environment (WE) reporting standard with a KPI related to the severity of WE deviations. Based on a literature study an iterative development of such a KPI has resulted in the Sustainable Risk Awareness Index (the SRA Index) and a visualization of it and its components using the Risk Awareness Triangle, also developed in this project. The development of the SRA Index is described and the index is exemplified with data from the electrical installation sector, the healthcare industry and one of Sweden’s largest private health company. Also the Risk Triangle is exemplified. The need for and the advantages of standardized methods to report WE deviations in companies sustainability reports are discussed. It is concluded that initial use of this KPI, according to management, fills an identified gap, it provides the management with a usable tool for systematic work environment overview and it supports their informed decision-making.
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24.
  • Hallén, Karin, et al. (author)
  • Ergonomisk utvärdering av rollatorprototyp ”Walker”
  • 2006
  • Reports (other academic/artistic)abstract
    • Denna rapport sammanfattar en jämförande studie av Trionics rollatorprototyp ”Walker” och två konventionella utomhusrollatorer. Studien har omfattat litteraturgenomgång, tekniska tester främst avseende forcering av hinder, samt användartester med tio rollatoranvändare som efter ett par veckors provanvändning av ”Walker” jämfört denna med sin ordinarie rollator. Vid användartesterna har främst intervjuer, subjektiva skattningar och EMG analys använts. Den ergonomiska analysen visar att Walker är överlägsen de konventionella rollatorerna vid passage av typiska hinder, såsom trottoarkanter och trädrötter. Kraftåtgången för att forcera en trottoarkant uppmättes till att vara 6-12 gånger större för de testade konventionella rollatorerna jämfört med Walker. I användarutvärderingen fick Walker högre betyg i alla testade utomhusmiljöer jämfört med användarnas ordinarie rollatorer. Den enda miljön där Walker bedömdes ha en sämre funktion än de medverkandes ordinarie rollator var i affärer. Dessutom uppskattas flera andra funktioner av användarna, såsom designen, bromsen och värdefickan. Däremot har Walker vissa brister gentemot konventionella rollatorer vad avser övrig hanterbarhet som hopfällning och smidighet vid passage genom dörrar etc. Speciellt de äldre användarna upplevde att Walker behöver vidareutvecklas i dessa avseenden. I rapporten ges förslag på förbättringar av Walker, såväl från författarna som från de medverkande i studien.   Efter avslutad testperiod fick de medverkande användarna svara på frågan om de ville behålla Walker i stället för sin ordinarie rollator. Av de nio som svarade ville sju hellre behålla Walker rollatorn. Samtliga fem medverkande som använde rollator pga. av funktionsnedsättning orsakad av handikapp eller sjukdom ville behålla Walker medan hälften av dem som använde rollator pga. åldersskäl ville behålla den. Huvudslutsatsen av studien är att Walker är ergonomiskt fördelaktig jämfört med konventionella utomhusrollatorer i flera avseenden, speciellt vid användning i terräng och vid hinderpassage. Den upplevs mycket positivt av de yngre medverkande i utvärderingen. Förbättringspotential har konstaterats för vissa funktioner, speciellt vad avser hantering i trånga miljöer och möjligheten att fälla ihop rollatorn.
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25.
  • Hallén, Karin, et al. (author)
  • Studie av pressmaskiner för VS-arbete
  • 2006
  • Reports (other academic/artistic)abstract
    • I denna rapport redovisas resultaten av en studie om pressmaskiner på uppdrag av parterna VVS Installatörerna och Byggnads. Tidigare har det uppmärksammats att maskinen är tung och att arbete med den ofta sker i ogynnsamma arbetsställningar över axelhöjd. Målet med projektet har varit att göra en översiktlig kartläggning av vilka maskiner som används för att pressa ihop VS-rör samt att göra en bedömning av arbetsmiljöaspekterna av detta monteringsarbete. Det har genomförts med montörer från tre företag i Stockholmsområdet. En litteraturstudie har genomförts och sammanställts. Arbetsplatsanalyser har gjorts med tio medverkande montörer. Vid dessa har subjektiva metoder såsom intervjuer och skattningar med VIDAR och Borgs CR-10 skala använts och objektiva metoder såsom EMG-metoder, biomekaniska datorsimuleringar och beräkningar. Resultaten visar att det finns olika maskin- och kopplingstyper, men inte någon gemensam standard för maskiner, backar eller kopplingar. I rapporten ges en sammanställning av de maskintyper som de återförsäljare och rörföretag som medverkat anser vara vanligast. Den ergonomiska analysen visar att många av de arbetsmoment med pressmaskin i tak som analyserats är olämpliga ur ergonomisk synpunkt. Arbetsställningarna vid fogning av rör i tak leder till ogynnsamma belastningar. Man arbetar ofta med armarna över axelhöjd, med vridna och böjda arbetsställningar och leder nära eller i ytterläge vilket bidrar till detta. De hanterade maskinerna och backarna (käftarna) som påträffats i studien väger tillsammans mellan 2,5 och 9 kg. I hur stor omfattning pressfogar används har varit svårt att klargöra i studien. Kontaktpersonerna på rörföretagen och återförsäljarna samt montörerna som medverkat i studien bedömde att 40 % eller mer av alla rörfogar pressas. Detta motsägs dock av det faktum att det var svårt att hitta objekt i Stockholmsområdet där man använde pressfogning under den sexveckorsperiod som fältstudien genomfördes. Arbetet som utförs över axelhöjd med att iordningsställa rör inför fogning samt fogning uppskattas av montörerna utgöra ungefär en tredjedel av arbetstiden. Av denna tid utgör själva fogningen en liten del. Används pressning är den muskuloskeletala belastningen högre än vid svetsning/lödning, men fogningstiden är kortare vid pressning än vid svetsning/lödning. En slutsats av studien är att arbete med att pressfoga rör i tak är ergonomiskt sett olämpligt. De ogynnsamma arbetsställningarna i sig är en huvudorsak till detta. Å andra sidan medför de befintliga alternativa arbetsmetoderna också höga belastningar, främst genom att arbetsställningarna är likartade. Därför kan även de befintliga alternativa metoderna vara ogynnsamma, även om dessa inte varit i fokus i denna studie. I rapporten ges även förslag på fortsatt arbete, t.ex. utveckling av nya koncept för fogning av rör. Ett annat är en kartläggning av hur mycket man exponeras för ogynnsamma arbetsställningar och andra riskfaktorer vid olika fogningsmetoder, samt mer information om återhämtningstider efter sådant arbete. Det skulle ge ett bättre underlag för prioriteringar i arbetsmiljöarbetet, eftersom man i den ergonomiska bedömningen också bör väga in typ av arbete (statiskt/dynamiskt) och tidsaspekter (bl.a. exponeringstid).
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26.
  • Hydén, Håkan, et al. (author)
  • Arbetsmiljölagstiftningen
  • 2008
  • In: Arbete och teknik på människans villkor.. - 9789173650373 ; , s. 665-700
  • Book chapter (peer-reviewed)
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27.
  • Hydén, Håkan, et al. (author)
  • Work Environment legislation
  • 2009
  • In: Work and technology on human terms. - 9789173650588 ; , s. 659-694
  • Book chapter (peer-reviewed)
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28.
  • Insanic, Jasmina, et al. (author)
  • Expert user perspectives of the Ergo-Index model for analysis of work tasks
  • 2017
  • In: NES2017 Conference Proceedings. - Lund : Lund University. ; , s. 313-320
  • Conference paper (peer-reviewed)abstract
    • The purpose of this study is to evaluate an updated beta version of Ergo-Index, a digital tool for ergonomic risk assessments. The evaluation was performed with 15 expert users who assessed type, distance, height and exposure time of certain work tasks, as well as the usability of the tool. In conclusion, the users find the present state of the Ergo-Index suitable as a first screening method. Assessments of lifting work have the greatest inter-rater reliability. Further development of the digitalized version of the tool is needed to improve accuracy assessing input regarding pushing and pulling work tasks, and to increase usability.
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29.
  • Jungestrand, Linda, et al. (author)
  • Family member perspectives on intensive care unit in-person visiting restrictions during the COVID-19 pandemic: A qualitative study.
  • 2023
  • In: Intensive & critical care nursing. - : Elsevier BV. - 1532-4036 .- 0964-3397. ; 75
  • Journal article (peer-reviewed)abstract
    • Family member presence in the intensive care unit is important for patient well-being and recovery. Limitations to visits increase the risk of psychological distress in family members. During the COVID-19 pandemic, in-person visiting restrictions were introduced to prevent the spread of infection.To explore the experience of in-person visiting restrictions imposed during the pandemic on family members of patients with COVID-19 admitted to an intensive care unit.Qualitative method with thematic analysis. Individual semi-structured telephone interviews were conducted.We interviewed 21 family members. The results are presented in one overall theme with two main themes and five sub-themes. The theme 'Striving for closeness even at a distance describes the experience of being kept at a physical distance when participants needed closeness the most. Even participants who were allowed in-person visits perceived a 'distance' due to personal protective equipment or because they could only view the patient from a window. Participants reported that contact with and information about the patient was of utmost importance. Visits were viewed as essential in providing for the patient's wellbeing. Meaningful contact with the ICU team was vital for getting useful information. Phone calls became a lifeline, with digital aids such as video calls used occasionally to overcome the feeling of distance.Visiting restrictions imposed during the COVID-19 pandemic made straightforward and comprehensible communication of information from the ICU team more essential to reduce family members' perceptions of distance and exclusion from the intensive care unit.
  •  
30.
  • Karlsson, Stig, et al. (author)
  • Design processes
  • 2009
  • In: Work and technology on human terms. - : Prevent. - 9789173650588
  • Book chapter (pop. science, debate, etc.)
  •  
31.
  • Karlsson, Stig, et al. (author)
  • Metoder
  • 2008
  • In: Arbete och teknik på människans villkor. - Stockholm : Arbetarskyddsnämnden. - 9789173650373 ; , s. 463-566
  • Book chapter (pop. science, debate, etc.)
  •  
32.
  • Karlsson, Stig, et al. (author)
  • Utvecklingsprocesser
  • 2008
  • In: Arbete och teknik på människans villkor. - Stockholm : Prevent. - 9789173650373 ; , s. 38-
  • Book chapter (other academic/artistic)
  •  
33.
  •  
34.
  • Koettgen, Anna, et al. (author)
  • Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
  • 2013
  • In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 45:2, s. 145-154
  • Journal article (peer-reviewed)abstract
    • Elevated serum urate concentrations can cause gout, a prevalent and painful inflammatory arthritis. By combining data from >140,000 individuals of European ancestry within the Global Urate Genetics Consortium (GUGC), we identified and replicated 28 genome-wide significant loci in association with serum urate concentrations (18 new regions in or near TRIM46, INHBB, SEMBT1, TMEM171, VEGFA, BAZ1B, PRKAG2, STC1, HNF4G, A1CF, ATXN2, UBE2Q2, IGF1R, NFAT5, MAF, HLF, ACVR1B-ACVRL1 and B3GNT4). Associations for many of the loci were of similar magnitude in individuals of non-European ancestry. We further characterized these loci for associations with gout, transcript expression and the fractional excretion of urate. Network analyses implicate the inhibins-activins signaling pathways and glucose metabolism in systemic urate control. New candidate genes for serum urate concentration highlight the importance of metabolic control of urate production and excretion, which may have implications for the treatment and prevention of gout.
  •  
35.
  • Lagerström, Gunnar, et al. (author)
  • Arbetsmiljö och ekonomi
  • 2008. - 1:1
  • In: Arbete och teknik på människans villkor. - Stockholm : Prevent. - 9789173650373 ; , s. 637-662
  • Book chapter (pop. science, debate, etc.)
  •  
36.
  • Lagerström, Gunnar, et al. (author)
  • Arbetsmiljö och ekonomi
  • 2015
  • In: Arbete och teknik på människans villkor. - Stockholm : Prevent. - 9789173651950 ; , s. 647-672
  • Book chapter (other academic/artistic)
  •  
37.
  •  
38.
  • Lagerström, Gunnar, et al. (author)
  • Work environment and economics
  • 2009. - 1:1
  • In: Work and Technology on Human Terms. - Stockholm : Prevent. - 9789173650588 ; , s. 1-718
  • Book chapter (pop. science, debate, etc.)
  •  
39.
  • Lind, Carl, et al. (author)
  • A practitioner model for assessing manual lifting and lowering operations : included in the RAMP tool
  • 2015
  • In: The 19th Triennial Congress of the International Ergonomics Association.
  • Conference paper (peer-reviewed)abstract
    • A recently developed model intended to be used by practitioners and ergonomists in themanufacturing and logistics industry for assessment of physical ergonomic risks related to manuallifting and lowering operations is presented. The model is constructed using the revised NIOSH liftingequation (RNLE) as a basis, but it has been modified to enhance its usability, regarding (1)simplifications of the existing factors in the RNLE, (2) adding new factors and (3) a more conservativejudgment of lifts performed at low and high vertical heights. In addition, a survey regarding theusability of the new lifting model including twenty-two ergonomists/physiotherapists is presented,
  •  
40.
  • Lind, Carl (author)
  • Assessment and design of industrial manual handling to reduce physical ergonomics hazards : – use and development of assessment tools
  • 2017
  • Doctoral thesis (other academic/artistic)abstract
    • Despite efforts of reducing harmful physical ergonomics exposures related to manual handling, the occurrence of heavy or repetitive manual handling, and non-neutral postures is high in many occupational sectors. To reduce these exposures, interventions and job design strategies can utilize risk assessment. A need was identified of an observation-based tool which supported occupational health and safety practitioners for assessments of risk factors related to manual handling.The aim of this thesis was to explore the use and important usability-related aspects of observation-based assessment tools among professional ergonomists, and to develop new research based assessment and screening tools, to present their scientific basis and to evaluate their reliability and usability. A web-based questionnaire was employed to gain knowledge on the use and usability aspects of risk assessment tools among ergonomists in Sweden. The assessment tools RAMP I and RAMP II were developed in an iterative process, including literature searches, expert group judgments, and with input from more than 80 practitioners. The reliability and usability evaluations included assessments and ratings by practitioners.The thesis points to a low use of several internationally spread assessment tools among Swedish ergonomists, and a relatively higher use of tools promoted by the Swedish Work Environment Authority. Several usability-related aspects were identified as important, such as being easy and quick to use, its ability to communicate and visualize the results, and its ability to facilitate improvement measures. The developed tools support assessment of a broad range of risk factors related to manual handling. The thesis supports that assessments with acceptable reliability can be achieved for the majority of items of the two developed tools. The thesis supports that the tools are usable in supporting risk assessments targeting risk factors related to industrial manual handling.
  •  
41.
  • Lind, Carl, et al. (author)
  • Development and evaluation of RAMP I : a practitioner tool for screening for musculoskeletal disorder risk factors in manual handling
  • 2017
  • Other publication (other academic/artistic)abstract
    • RAMP I is a screening tool developed to support practitioners in screening for work-related musculoskeletal disorder risk factors related to manual handling. RAMP I, which is part of the RAMP tool, is based on research based studies combined with expert group judgments. More than 80 practitioners participated in the development of RAMP I. The tool constitutes of dichotomous assessment items grouped in seven categories. Acceptable reliability was found for a majority of the assessment items for 15 practitioners who were given 1h training. The usability evaluation points to RAMP I being usable for screening for musculoskeletal disorder risk factors, i.e., usable for assessing risks, usable as a decision base, has clear results, and the time needed for an assessment is acceptable. It is concluded that RAMP I is a valuable tool for practitioners.
  •  
42.
  • Lind, Carl, et al. (author)
  • Development and evaluation of RAMP I – a practitioner’s tool for screening of musculoskeletal disorder risk factors in manual handling
  • 2019
  • In: International Journal of Occupational Safety and Ergonomics (JOSE). - : Taylor & Francis. - 1080-3548 .- 2376-9130. ; 25:2, s. 165-180
  • Journal article (peer-reviewed)abstract
    • RAMP I is a screening tool developed to support practitioners in screening for work-related musculoskeletal disorder riskfactors related to manual handling. RAMP I, which is part of the RAMP tool, is based on research-based studies combinedwith expert group judgments. More than 80 practitioners participated in the development of RAMP I. The tool consistsof dichotomous assessment items grouped into seven categories. Acceptable reliability was found for a majority of theassessment items for 15 practitioners who were given 1 h of training. The usability evaluation points to RAMP I beingusable for screening for musculoskeletal disorder risk factors, i.e., usable for assessing risks, being usable as a decision base,having clear results and that the time needed for an assessment is acceptable. It is concluded that RAMP I is a usable toolfor practitioners.
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43.
  •  
44.
  •  
45.
  • Lind, Carl Mikael, et al. (author)
  • Development and evaluation of RAMP II - a practitioner’s tool for assessing musculoskeletal disorder risk factors in industrial manual handling
  • 2020
  • In: Ergonomics. - : Informa UK Limited. - 0014-0139 .- 1366-5847. ; 63:4, s. 477-504
  • Journal article (peer-reviewed)abstract
    • RAMP II is an observation-based tool developed for assessing a wide range of musculoskeletal disorder risk factors related to industrial manual handling. RAMP II, which is part of the RAMP tool, is based on research studies and expert judgments. The assessment relies mainly on direct or video observations of the work being assessed, but additionally on measured push/pull forces and weights of handled objects, and on perceived workload and discomfort. Over 80 practitioners participated in the development of the tool. According to the evaluations, 73% of the assessment items evaluated had acceptable reliability, and the majority of the potential end-users reported that RAMP II is usable for assessing risks and as a decision base. It is concluded that this study provides support that RAMP II is usable for risk assessment of musculoskeletal disorder risk factors in industrial manual handling. Practitioner summary: RAMP II is an observation-based assessment tool for screening and assessing major musculoskeletal exposures in industrial manual handling jobs. Over 80 practitioners participated in the development of the tool. This study provides support that RAMP II is usable for risk assessment of musculoskeletal disorder risk factors in industrial manual handling. Abbreviations: CTS: carpal tunnel syndrome; HARM: the Hand Arm Risk Assessment method; IMP: intramuscular pressure; κw: linearly weighted kappa; LBD: lower back disorders; LBP: lower back pain; MAWL: maximum acceptable weight of lift; MHO: manual handling operations; MSD: musculoskeletal disorder; MNSD: neck-shoulder disorder; NSP: neck-shoulder pain; OCRA: the Occupational Repetitive Action methods; OHS: occupational health and safety; PABAK: prevalence and bias adjusted kappa; p0: proportion of agreement; RAMP: Risk Assessment and Management tool for manual handling Proactively; ROM: range of motion; RPL: risk and priority level; RSI: the Revised Strain Index; RULA: the Rapid Upper Limb Assessment; SWEA: Swedish Work Environment Authority; UEMSDs: upper-extremity work-related musculoskeletal disorders; WMSD: work-related musculoskeletal disorder; WRMSD: work-related musculoskeletal disorder; workday8h: eight hours workday.
  •  
46.
  • Lind, Carl, et al. (author)
  • RAMP - Development of a risk assessment tool
  • 2012
  • In: NES2012 Ergonomics for sustainability and growth. - Stockholm. - 9789163711497 ; , s. 14s-
  • Conference paper (peer-reviewed)abstract
    • IntroductionManual Materials Handling (MMH) and working in awkward postures are still important causes of MSDs. Proper ergonomic conditions can contribute to reduce absence from work, and are important prerequisites to ensure high quality and productivity. Risk assessment can be used to improve the working conditions by identifying important risk factors and support communication between key stakeholders in order to improve the working conditions.This paper presents an ongoing project called RAMP (Risk management Assessment tool for Manual handling Proactively), reported e.g. at NES 2011. The aim of the project is to develop a freely accessible load ergonomic risk assessment tool and to gain knowledge of contributing factors for implementation and usability of such a tool. The RAMP-tool is developed for assessing risk of MSDs, support communication of the main risk factors among stakeholders and support effective interventions. The project, mainly financed by AFA Insurance, is conducted in collaboration between KTH and companies in the manufacturing industry, mainly Arla Foods and Scania CV.MethodsThis far an overview of risk assessment tools which can be used to assess MMH activities and potentially be used by companies or OSH personnel has been performed including e.g. KIM, QEC, ART Tool, SES and Washington State Checklist. Interviews with companies in the manufacturing industry have been performed to gain insight of the companies’ use of risk assessment tools and their perception of their usability.ResultsThe tool consists of two levels, RAMP I and RAMP II. The first level is intended for quick screening of work stations of occurrence (or not) of risk factors. If the screening indicates an occurrence of a risk factor, a more thorough analysis with the second level could be performed. RAMP II can be used for a more detailed analysis of the exposure to risk factors and point out the direction of possible improvements in order to reduce the exposure.A first prototype of the RAMP I has been evaluated by users, including managers, health and safety representatives, OSH personnel and workers.The tool will be further evaluated and refined after feedback from users. A preliminary version of the RAMP I will be presented at the conference and also preliminary results from the user tests.
  •  
47.
  • Lind, Carl, et al. (author)
  • RAMP: Risk Management Assessment Tool for Manual Handling Proactively
  • 2014
  • In: HUMAN FACTORS IN ORGANIZATIONAL DESIGN AND MANAGEMENT – XINORDIC ERGONOMICS SOCIETY ANNUAL CONFERENCE – 46. ; , s. 107-110
  • Conference paper (peer-reviewed)abstract
    • This paper presents an IT-based risk management tool called RAMP, risk assessment management tool for manual handling proactively. The tool consists of a checklist (RAMP I) and an assessment tool (RAMP II) which can be used to assess physicalrisk factors associated with manual handling activities in the production industry. The tool provides guidance for action plans and evaluations to promote improvement of occupational health and safety work at company level. Examples of the tool, its development and evaluation are presented.
  •  
48.
  • Lind, Carl, et al. (author)
  • Shifting to proactive risk management : Risk communication using the RAMP tool
  • 2016
  • In: Agronomy Research. - 1406-894X. ; 14:2, s. 513-524
  • Journal article (peer-reviewed)abstract
    • Ergonomic risk factors are major contributors to work-related musculoskeletaldisorders and quality deficiencies in the manufacturing industry. Due to lack of tools or systemsthat can support a systematic risk management of these production and health related factors, anew risk management tool (RAMP) was developed. In this paper, the risk communication system(the Results module) of this tool is presented along with a description of its development. Anexample of how it can be used, based on assessments performed in industry, is given. Anevaluation of its usability, which included twenty practitioners active in the industry, givessupport to the notion that the system is usable both for risk communication and as a decision base.
  •  
49.
  • Locke, Adam E, et al. (author)
  • Genetic studies of body mass index yield new insights for obesity biology.
  • 2015
  • In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 518:7538, s. 197-401
  • Journal article (peer-reviewed)abstract
    • Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P < 5 × 10(-8)), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ∼2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.
  •  
50.
  • Mazaheri, Ava, 1992- (author)
  • Beyond the Force: Redefining load exposure assessments of nutrunners for improved power tool ergonomics
  • 2023
  • Doctoral thesis (other academic/artistic)abstract
    • Reaction force exposure from handheld tightening tools (also known as nutrunners) constitutes an acknowledged contributor to musculoskeletal disorders among assembly operators, and are today not regulated by explicit limits. The research presented in this thesis aimed at contributing to the development of recommended exposure limits for, and assessments of, reaction loads from handheld right-angle and pistol-grip tightening tools.In order to address the thesis objectives, four research studies were conducted. A literature review was conducted to provide an overview of the current state of knowledge within the topic area. Knowledge gaps were identified by mapping available publications and based on those suggesting directions for further research. Thereafter, two psychophysically based experimental studies were conducted where acceptability limits related to load exposure from handheld tightening tools were derived for right-angle and pistol-grip tightening tools. Finally, an automotive manufacturer’s approach to evaluating and managing the use of handheld tightening tools was outlined by means of an interview study.As found through the literature review, four of the forty included publications had stated exposure limits (general recommendations) or acceptability limits (load acceptance as assessed by study participants) for reaction load exposure from handheld tightening tools. However, some of the reported limits did not consider relevant physical parameters, and some did not comply with modern power tool technologies. Based on this, it was suggested that researchers should emphasize physical quantities relevant to the reaction load such as impulse, express exposure limits in terms of reaction load relevant parameters (and not only the tightening torque), and further study modern power tool technologies.The experimental studies resulted in acceptability limits for right-angle and pistol-grip tightening tools expressed as screw-joint tightening torque (i.e. a task-related factor), where acceptable tightening torque limits were higher for the inertia-controlled tightening program compared to the continuous drive tightening program, in both studies. In addition, corresponding acceptable reaction load levels (i.e. the exposure) were derived, indicating load levels resulting from the tool use that the study participants assessed as acceptable for an 8-hour workday. It should be noted that the experimental times on which the acceptability limits are based were limited, and that the acceptability limits therefore should not be prescribed to full workdays.From the interview study, three main topic categories were identified based on the interviewees’ responses: ‘A holistic approach’, ‘Information and knowledge availability’ and ‘Negotiating criteria’. Within the studied automotive organization, a comprehensive approach to ergonomics assessments is incorporate, where both objective and subjective evaluations form the basis for addressing physically demanding tool use situations. Further, it was found that there are different instances where the employees lack sufficient knowledge related to the tools, and which can influence the employment of handheld tightening tools. In addition, it was found that criteria such as safety and quality could in some situations compete with ergonomics efforts. In conclusion, the findings from this thesis can contribute to the development of recommended exposure limits and evaluation methods for reaction load exposure from handheld tightening tools. Policymakers could utilize the insights presented in this thesis to form general guidelines directed at power tool manufacturers as well as tool using organizations. Through standardized guidelines, reaction loads from handheld tightening tools, which is one of the contributors to MSDs within assembly work, can be managed and reduced. 
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