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Search: WFRF:(San Jose Garcia I.)

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  • Jin, Shoko, et al. (author)
  • The wide-field, multiplexed, spectroscopic facility WEAVE : Survey design, overview, and simulated implementation
  • 2024
  • In: Monthly notices of the Royal Astronomical Society. - : Oxford University Press. - 0035-8711 .- 1365-2966. ; 530:3, s. 2688-2730
  • Journal article (peer-reviewed)abstract
    • WEAVE, the new wide-field, massively multiplexed spectroscopic survey facility for the William Herschel Telescope, saw first light in late 2022. WEAVE comprises a new 2-deg field-of-view prime-focus corrector system, a nearly 1000-multiplex fibre positioner, 20 individually deployable 'mini' integral field units (IFUs), and a single large IFU. These fibre systems feed a dual-beam spectrograph covering the wavelength range 366-959nm at R similar to 5000, or two shorter ranges at . After summarizing the design and implementation of WEAVE and its data systems, we present the organization, science drivers, and design of a five- to seven-year programme of eight individual surveys to: (i) study our Galaxy's origins by completing Gaia's phase-space information, providing metallicities to its limiting magnitude for similar to 3 million stars and detailed abundances for similar to 1.5 million brighter field and open-cluster stars; (ii) survey similar to 0.4 million Galactic-plane OBA stars, young stellar objects, and nearby gas to understand the evolution of young stars and their environments; (iii) perform an extensive spectral survey of white dwarfs; (iv) survey similar to 400 neutral-hydrogen-selected galaxies with the IFUs; (v) study properties and kinematics of stellar populations and ionized gas in z < 0.5 cluster galaxies; (vi) survey stellar populations and kinematics in field galaxies at 0.3 less than or similar to z less than or similar to 0.7; (vii) study the cosmic evolution of accretion and star formation using >1 million spectra of LOFAR-selected radio sources; and (viii) trace structures using intergalactic/circumgalactic gas at z > 2. Finally, we describe the WEAVE Operational Rehearsals using the WEAVE Simulator.
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  • Jakobsdottir, Johanna, et al. (author)
  • Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease
  • 2016
  • In: PLOS Genetics. - : Public Library of Science (PLoS). - 1553-7390 .- 1553-7404. ; 12:10
  • Journal article (peer-reviewed)abstract
    • We performed an exome-wide association analysis in 1393 late-onset Alzheimer's disease (LOAD) cases and 8141 controls from the CHARGE consortium. We found that a rare variant (P155L) in TM2D3 was enriched in Icelanders (similar to 0.5% versus < 0.05% in other European populations). In 433 LOAD cases and 3903 controls from the Icelandic AGES substudy, P155L was associated with increased risk and earlier onset of LOAD [odds ratio (95% CI) = 7.5 (3.5-15.9), p = 6.6x10(-9)]. Mutation in the Drosophila TM2D3 homolog, almondex, causes a phenotype similar to loss of Notch/Presenilin signaling. Human TM2D3 is capable of rescuing these phenotypes, but this activity is abolished by P155L, establishing it as a functionally damaging allele. Our results establish a rare TM2D3 variant in association with LOAD susceptibility, and together with prior work suggests possible links to the beta-amyloid cascade.
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  • Karska, A., et al. (author)
  • Water in star-forming regions with Herschel (WISH) III. Far-infrared cooling lines in low-mass young stellar objects
  • 2013
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 552
  • Journal article (peer-reviewed)abstract
    • Context. Understanding the physical phenomena involved in the earlierst stages of protostellar evolution requires knowledge of the heating and cooling processes that occur in the surroundings of a young stellar object. Spatially resolved information from its constituent gas and dust provides the necessary constraints to distinguish between different theories of accretion energy dissipation into the envelope.Aims. Our aims are to quantify the far-infrared line emission from low-mass protostars and the contribution of different atomic and molecular species to the gas cooling budget, to determine the spatial extent of the emission, and to investigate the underlying excitation conditions. Analysis of the line cooling will help us characterize the evolution of the relevant physical processes as the protostar ages.Methods. Far-infrared Herschel-PACS spectra of 18 low-mass protostars of various luminosities and evolutionary stages are studied in the context of the WISH key program. For most targets, the spectra include many wavelength intervals selected to cover specific CO, H2O, OH, and atomic lines. For four targets the spectra span the entire 55-200 mu m region. The PACS field-of-view covers similar to 47 '' with the resolution of 9.4 ''.Results. Most of the protostars in our sample show strong atomic and molecular far-infrared emission. Water is detected in 17 out of 18 objects (except TMC1A), including 5 Class I sources. The high-excitation H2O 8(18)-7(07) 63.3 mu m line (E-u/k(B) = 1071 K) is detected in 7 sources. CO transitions from J = 14-13 up to J = 49-48 are found and show two distinct temperature components on Boltzmann diagrams with rotational temperatures of similar to 350 K and similar to 700 K. H2O has typical excitation temperatures of similar to 150 K. Emission from both Class 0 and I sources is usually spatially extended along the outflow direction but with a pattern that depends on the species and the transition. In the extended sources, emission is stronger off source and extended on >= 10 000 AU scales; in the compact sample, more than half of the flux originates within 1000 AU of the protostar. The H2O line fluxes correlate strongly with those of the high-J CO lines, both for the full array and for the central position, as well as with the bolometric luminosity and envelope mass. They correlate less strongly with OH fluxes and not with [O I] fluxes. In contrast, [O I] and OH often peak together at the central position.Conclusions. The PACS data probe at least two physical components. The H2O and CO emission very likely arises in non-dissociative (irradiated) shocks along the outflow walls with a range of pre-shock densities. Some OH is also associated with this component, most likely resulting from H2O photodissociation. UV-heated gas contributes only a minor fraction to the CO emission observed by PACS, based on the strong correlation between the shock-dominated CO 24-23 line and the CO 14-13 line. [O I] and some of the OH emission probe dissociative shocks in the inner envelope. The total far-infrared cooling is dominated by H2O and CO, with the fraction contributed by [O I] increasing for Class I sources. Consistent with previous studies, the ratio of total far-infrared line emission over bolometric luminosity decreases with the evolutionary state.
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  • Kristensen, L., et al. (author)
  • Water in star-forming regions with Herschel (WISH) II. Evolution of 557 GHz 1(10)-1(01) emission in low-mass protostars
  • 2012
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 542
  • Journal article (peer-reviewed)abstract
    • Context. Water is a key tracer of dynamics and chemistry in low-mass star-forming regions, but spectrally resolved observations have so far been limited in sensitivity and angular resolution, and only data from the brightest low-mass protostars have been published. Aims. The first systematic survey of spectrally resolved water emission in 29 low-mass (L 10 km s(-1)). The water abundance in the outer cold envelope is low, greater than or similar to 10(-10). The different H2O profile components show a clear evolutionary trend: in the younger Class 0 sources the emission is dominated by outflow components originating inside an infalling envelope. When large-scale infall diminishes during the Class I phase, the outflow weakens and H2O emission all but disappears.
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  • Mottram, J. C., et al. (author)
  • Water in star-forming regions with Herschel (WISH)
  • 2014
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 572
  • Journal article (peer-reviewed)abstract
    • Context. Outflows are an important part of the star formation process as both the result of ongoing active accretion and one of the main sources of mechanical feedback on small scales. Water is the ideal tracer of these effects because it is present in high abundance for the conditions expected in various parts of the protostar, particularly the outflow. Aims. We constrain and quantify the physical conditions probed by water in the outflow-jet system for Class 0 and I sources. Methods. We present velocity-resolved Herschel HIFI spectra of multiple water-transitions observed towards 29 nearby Class 0/I protostars as part of the WISH guaranteed time key programme. The lines are decomposed into different Gaussian components, with each component related to one of three parts of the protostellar system; quiescent envelope, cavity shock and spot shocks in the jet and at the base of the outflow. We then use non-LTE radex models to constrain the excitation conditions present in the two outflow-related components. Results. Water emission at the source position is optically thick but effectively thin, with line ratios that do not vary with velocity, in contrast to CO. The physical conditions of the cavity and spot shocks are similar, with post-shock H-2 densities of order 10(5) -10(8) cm(-3) and H2O column densities of order 10(16) -10(18) cm(-2). H2O emission originates in compact emitting regions: for the spot shocks these correspond to point sources with radii of order 10-200 AU, while for the cavity shocks these come from a thin layer along the outflow cavity wall with thickness of order 1-30 AU. Conclusions. Water emission at the source position traces two distinct kinematic components in the outflow; J shocks at the base of the outflow or in the jet, and C shocks in a thin layer in the cavity wall. The similarity of the physical conditions is in contrast to off-source determinations which show similar densities but lower column densities and larger filling factors. We propose that this is due to the differences in shock properties and geometry between these positions. Class I sources have similar excitation conditions to Class 0 sources, but generally smaller line-widths and emitting region sizes. We suggest that it is the velocity of the wind driving the outflow, rather than the decrease in envelope density or mass, that is the cause of the decrease in H2O intensity between Class 0 and I sources.
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