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1.
  • Marconi, A., et al. (author)
  • ANDES, the high resolution spectrograph for the ELT : science case, baseline design and path to construction
  • 2022
  • In: GROUND-BASED AND AIRBORNE INSTRUMENTATION FOR ASTRONOMY IX. - : SPIE - International Society for Optical Engineering. - 9781510653504 - 9781510653498
  • Conference paper (peer-reviewed)abstract
    • The first generation of ELT instruments includes an optical-infrared high resolution spectrograph, indicated as ELT-HIRES and recently christened ANDES (ArmazoNes high Dispersion Echelle Spectrograph). ANDES consists of three fibre-fed spectrographs (UBV, RIZ, YJH) providing a spectral resolution of similar to 100,000 with a minimum simultaneous wavelength coverage of 0.4-1.8 mu m with the goal of extending it to 0.35-2.4 mu m with the addition of a K band spectrograph. It operates both in seeing- and diffraction-limited conditions and the fibre-feeding allows several, interchangeable observing modes including a single conjugated adaptive optics module and a small diffraction-limited integral field unit in the NIR. Its modularity will ensure that ANDES can be placed entirely on the ELT Nasmyth platform, if enough mass and volume is available, or partly in the Coude room. ANDES has a wide range of groundbreaking science cases spanning nearly all areas of research in astrophysics and even fundamental physics. Among the top science cases there are the detection of biosignatures from exoplanet atmospheres, finding the fingerprints of the first generation of stars, tests on the stability of Nature's fundamental couplings, and the direct detection of the cosmic acceleration. The ANDES project is carried forward by a large international consortium, composed of 35 Institutes from 13 countries, forming a team of more than 200 scientists and engineers which represent the majority of the scientific and technical expertise in the field among ESO member states.
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  • Marconi, Alessandro, et al. (author)
  • ELT-HIRES, the high resolution spectrograph for the ELT : Phase A study and path to construction
  • 2020
  • In: Ground-based and Airborne Instrumentation for Astronomy VIII. - : SPIE - International Society for Optical Engineering. - 9781510636828 - 9781510636811
  • Conference paper (peer-reviewed)abstract
    • HIRES is the high-resolution spectrograph of the European Extremely Large Telescope at optical and near-infrared wavelengths. It consists of three fibre-fed spectrographs providing a wavelength coverage of 0.4-1.8 µm (goal 0.35-2.4 µm) at a spectral resolution of 100,000. The fibre-feeding allows HIRES to have several, interchangeable observing modes including a SCAO module and a small diffraction-limited IFU in the NIR. Therefore, it will be able to operate both in seeing- and diffraction-limited modes. Its modularity will ensure that HIRES can be placed entirely on the Nasmyth platform, if enough mass and volume is available, or part on the Nasmyth and part in the Coud`e room. ELT-HIRES has a wide range of science cases spanning nearly all areas of research in astrophysics and even fundamental physics. Among the top science cases there are the detection of biosignatures from exoplanet atmospheres, finding the fingerprints of the first generation of stars (PopIII), tests on the stability of Nature’s fundamental couplings, and the direct detection of the cosmic acceleration. The HIRES consortium is composed of more than 30 institutes from 14 countries, forming a team of more than 200 scientists and engineers.
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  • Szabo, Gy M., et al. (author)
  • Transit timing variations of AU Microscopii b and c*
  • 2022
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 659
  • Journal article (peer-reviewed)abstract
    • Here we report large-amplitude transit timing variations (TTVs) for AU Microcopii b and c as detected in combined TESS (2018, 2020) and CHEOPS (2020, 2021) transit observations. AU Mic is a young planetary system with a debris disk and two transiting warm Neptunes. A TTV on the order of several minutes was previously reported for AU Mic b, which was suggested to be an outcome of mutual perturbations between the planets in the system. In 2021, we observed AU Mic b (five transits) and c (three transits) with the CHEOPS space telescope to follow-up the TTV of AU Mic b and possibly detect a TTV for AU Mic c. When analyzing TESS and CHEOPS 2020-2021 measurements together, we find that a prominent TTV emerges with a full span of >= 23 min between the two TTV extrema. Assuming that the period change results from a periodic process -such as mutual perturbations- we demonstrate that the times of transits in the summer of 2022 are expected to be 30-85 min later than predicted by the available linear ephemeris.
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  • Bruno, G., et al. (author)
  • Detailed cool star flare morphology with CHEOPS and TESS
  • 2024
  • In: Astronomy and Astrophysics. - 0004-6361 .- 1432-0746. ; 686
  • Journal article (peer-reviewed)abstract
    • Context. White-light stellar flares are proxies for some of the most energetic types of flares, but their triggering mechanism is still poorly understood. As they are associated with strong X and ultraviolet emission, their study is particularly relevant to estimate the amount of high-energy irradiation onto the atmospheres of exoplanets, especially those in their stars’ habitable zone. Aims. We used the high-cadence, high-photometric capabilities of the CHEOPS and TESS space telescopes to study the detailed morphology of white-light flares occurring in a sample of 130 late-K and M stars, and compared our findings with results obtained at a lower cadence. Methods. We employed dedicated software for the reduction of 3 s cadence CHEOPS data, and adopted the 20 s cadence TESS data reduced by their official processing pipeline. We developed an algorithm to separate multi-peak flare profiles into their components, in order to contrast them to those of single-peak, classical flares. We also exploited this tool to estimate amplitudes and periodicities in a small sample of quasi-periodic pulsation (QPP) candidates. Results. Complex flares represent a significant percentage (≳30%) of the detected outburst events. Our findings suggest that high-impulse flares are more frequent than suspected from lower-cadence data, so that the most impactful flux levels that hit close-in exoplanets might be more time-limited than expected. We found significant differences in the duration distributions of single and complex flare components, but not in their peak luminosity. A statistical analysis of the flare parameter distributions provides marginal support for their description with a log-normal instead of a power-law function, leaving the door open to several flare formation scenarios. We tentatively confirmed previous results about QPPs in high-cadence photometry, report the possible detection of a pre-flare dip, and did not find hints of photometric variability due to an undetected flare background. Conclusions. The high-cadence study of stellar hosts might be crucial to evaluate the impact of their flares on close-in exoplanets, as their impulsive phase emission might otherwise be incorrectly estimated. Future telescopes such as PLATO and Ariel, thanks to their high-cadence capability, will help in this respect. As the details of flare profiles and of the shape of their parameter distributions are made more accessible by continuing to increase the instrument precision and time resolution, the models used to interpret them and their role in star-planet interactions might need to be updated constantly.
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5.
  • Meier Valdes, E., et al. (author)
  • Investigating the visible phase-curve variability of 55 Cnc e
  • 2023
  • In: Astronomy and Astrophysics. - 0004-6361 .- 1432-0746. ; 677
  • Journal article (peer-reviewed)abstract
    • Context. 55 Cnc e is an ultra-short period super-Earth transiting a Sun-like star. Previous observations in the optical range detected a time-variable flux modulation that is phased with the planetary orbital period, whose amplitude is too large to be explained by reflected light and thermal emission alone. Aims. The goal of the study is to investigate the origin of the variability and timescale of the phase-curve modulation in 55 Cnc e. To this end, we used the CHaracterising ExOPlanet Satellite (CHEOPS), whose exquisite photometric precision provides an opportunity to characterise minute changes in the phase curve from one orbit to the next. Methods. CHEOPS observed 29 individual visits of 55 Cnc e between March 2020 and February 2022. Based on these observations, we investigated the different processes that could be at the origin of the observed modulation. In particular, we built a toy model to assess whether a circumstellar torus of dust driven by radiation pressure and gravity might match the observed flux variability timescale. Results. We find that the phase-curve amplitude and peak offset of 55 Cnc e do vary between visits. The sublimation timescales of selected dust species reveal that silicates expected in an Earth-like mantle would not survive long enough to explain the observed phase-curve modulation. We find that silicon carbide, quartz, and graphite are plausible candidates for the circumstellar torus composition because their sublimation timescales are long. Conclusions. The extensive CHEOPS observations confirm that the phase-curve amplitude and offset vary in time. We find that dust could provide the grey opacity source required to match the observations. However, the data at hand do not provide evidence that circumstellar material with a variable grain mass per unit area causes the observed variability. Future observations with the James Webb Space Telescope (JWST) promise exciting insights into this iconic super-Earth.
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6.
  • Sarajlić, M., et al. (author)
  • Germanium "hexa" detector : Production and testing
  • 2017
  • In: Journal of Instrumentation. - 1748-0221. ; 12:1
  • Journal article (peer-reviewed)abstract
    • Here we present new result on the testing of a Germanium sensor for X-ray radiation. The system is made of 3 × 2 Medipix3RX chips, bump-bonded to a monolithic sensor, and is called "hexa". Its dimensions are 45 × 30 mm2 and the sensor thickness was 1.5 mm. The total number of the pixels is 393216 in the matrix 768 × 512 with pixel pitch 55 μ m. Medipix3RX read-out chip provides photon counting read-out with single photon sensitivity. The sensor is cooled to -126°C and noise levels together with flat field response are measured. For -200 V polarization bias, leakage current was 4.4 mA (3.2 μ A/mm2). Due to higher leakage around 2.5% of all pixels stay non-responsive. More than 99% of all pixels are bump bonded correctly. In this paper we present the experimental set-up, threshold equalization procedure, image acquisition and the technique for bump bond quality estimate.
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  • Hupin, D, et al. (author)
  • Cardiovascular Autonomic Function Changes and Predictors During a 2-Year Physical Activity Program in Rheumatoid Arthritis: A PARA 2010 Substudy
  • 2021
  • In: Frontiers in medicine. - : Frontiers Media SA. - 2296-858X. ; 8, s. 788243-
  • Journal article (peer-reviewed)abstract
    • Background: Chronic inflammation leads to autonomic dysfunction, which may contribute to the increased risk of cardiovascular diseases (CVD) in patients with rheumatoid arthritis (RA). Exercise is known to restore autonomic nervous system (ANS) activity and particularly its parasympathetic component. A practical clinical tool to assess autonomic function, and in particular parasympathetic tone, is heart rate recovery (HRR). The aim of this substudy from the prospective PARA 2010 study was to determine changes in HRR post-maximal exercise electrocardiogram (ECG) after a 2-year physical activity program and to determine the main predictive factors associated with effects on HRR in RA.Methods: Twenty-five participants performed physiotherapist-guided aerobic and muscle-strengthening exercises for 1 year and were instructed to continue the unsupervised physical activity program autonomously in the next year. All participants were examined at baseline and at years 1 and 2 with a maximal exercise ECG on a cycle ergometer. HRR was measured at 1, 2, 3, 4, and 5 min following peak heart rate during exercise. Machine-learning algorithms with the elastic net linear regression models were performed to predict changes in HRR1 and HRR2 at 1 year and 2 years of the PARA program.Results: Mean age was 60 years, range of 41–73 years (88% women). Both HRR1 and HRR2 increased significantly from baseline to year 1 with guided physical activity and decreased significantly from year 1 to year 2 with unsupervised physical activity. Blood pressure response to exercise, low BMI, and muscular strength were the best predictors of HRR1/HRR2 increase during the first year and HRR1/HRR2 decrease during the second year of the PARA program.Conclusion: ANS activity in RA assessed by HRR was improved by guided physical activity, and machine learning allowed to identify predictors of the HRR response at the different time points. HRR could be a relevant marker of the effectiveness of physical activity recommended in patients with RA at high risk of CVD. Very inactive and/or high CVD risk RA patients may get substantial benefits from a physical activity program.
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12.
  • Jaksic, Z., et al. (author)
  • Gradient-index infrared metamaterials based on metal-dielectric submicrometer pillar arrays
  • 2013
  • In: 2013 11th International Conference on Telecommunications in Modern Satellite, Cable and Broadcasting Services, TELSIKS 2013. - : IEEE. - 9781479909025 ; , s. 21-24
  • Conference paper (peer-reviewed)abstract
    • This paper presents the design and microfabrication of a two-dimensional metal-dielectric metamaterial structure based on an array of pillars with submicrometer diameters and heights. The diameters of pillars periodically vary along one axis in a sawtooth fashion and are constant along the other. The electromagnetic field distribution within this graded metamaterial was considered utilizing an accurate analytical approach. The pillar arrays were fabricated in photoresist and subsequently covered with a sputter-deposited aluminum film. Structures were defined by direct laser writing in photoresist film. Controlled overexposure has been applied in order to make pillar features smaller than the nominal resolution of the equipment. The structures were characterized by optical and atomic force microscopy and by angle-dependent Fourier Transform infrared spectroscopy. The produced graded frequency-selective surfaces may be used e.g. in sensing.
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13.
  • Jakšić, Z., et al. (author)
  • Two-dimensional gradient-index metamaterial with sawtooth profile
  • 2013
  • In: Microwave Review. - 1450-5835. ; 19:2, s. 96-101
  • Journal article (peer-reviewed)abstract
    • We investigate theoretically and experimentally a binary metal-dielectric metamaterial with a sawtooth profile. The structure consists of a two-dimensional array of pillars with submicrometer diameters. The pillar diameters linearly vary along one axis and are constant along the other. This furnishes a serrated spatial profile of effective refractive index along a single axis. We first present a set of analytical solutions defining the electromagnetic fields in such a structure. Further we give the results of our experimental fabrication of gradient metamaterial with a sawtooth spatial profile. The basic material for pillars was photoresist. Their geometry was defined using direct laser writing. Resist was overexposed in controlled manner in order to obtain pillars with diameters below the nominal resolution of the laser writer. The microfabricated pillars were coated by a sputter-deposited aluminum film. For characterization we utilized optical and atomic force microscopy and angledependent Fourier Transform infrared spectroscopy. We envision the applicability of our graded metasurfaces in transformation optics.
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  • Pennicard, David, et al. (author)
  • LAMBDA 2M GaAs - A multi-megapixel hard X-ray detector for synchrotrons
  • 2018
  • In: Journal of Instrumentation. - 1748-0221. ; 13:1
  • Journal article (peer-reviewed)abstract
    • Synchrotrons can provide very intense and focused X-ray beams, which can be used to study the structure of matter down to the atomic scale. In many experiments, the quality of the results depends strongly on detector performance; in particular, experiments studying dynamics of samples require fast, sensitive X-ray detectors. "LAMBDA" is a photon-counting hybrid pixel detector system for experiments at synchrotrons, based on the Medipix3 readout chip. Its main features are a combination of comparatively small pixel size (55 μm), high readout speed at up to 2000 frames per second with no time gap between images, a large tileable module design, and compatibility with high-Z sensors for efficient detection of higher X-ray energies. A large LAMBDA system for hard X-ray detection has been built using Cr-compensated GaAs as a sensor material. The system is composed of 6 GaAs tiles, each of 768 by 512 pixels, giving a system with approximately 2 megapixels and an area of 8.5 by 8.5 cm2. While the sensor uniformity of GaAs is not as high as that of silicon, its behaviour is stable over time, and it is possible to correct nonuniformities effectively by postprocessing of images. By using multiple 10 Gigabit Ethernet data links, the system can be read out at the full speed of 2000 frames per second. The system has been used in hard X-ray diffraction experiments studying the structure of samples under extreme pressure in diamond anvil cells. These experiments can provide insight into geological processes. Thanks to the combination of high speed readout, large area and high sensitivity to hard X-rays, it is possible to obtain previously unattainable information in these experiments about atomic-scale structure on a millisecond timescale during rapid changes of pressure or temperature. 
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  • Sarajlic, M., et al. (author)
  • Progress on TSV technology for Medipix3RX chip
  • 2017
  • In: Journal of Instrumentation. - 1748-0221. ; 12
  • Journal article (peer-reviewed)abstract
    • The progress of Through Silicon Via (TSV) technology for Medipix3RX chip done at DESY is presented here. The goal of this development is to replace the wire bonds in X-ray detectors with TSVs, in order to reduce the dead area between detectors. We obtained the first working chips assembled together with Si based sensors for X-ray detection. The 3D integration technology, including TSV, Re-distribution layer deposition, bump bonding to the Si sensor and bump bonding to the carrier PCB, was done by Fraunhofer Institute IZM in Berlin. After assembly, the module was successfully tested by recording background radiation and making X-ray images of small objects. The active area of the Medipix3RX chip is 14.1 mm x 14.1 mm or 256 x 256 pixels. During TSV processing, the Medipix3RX chip was thinned from 775 mu m original thickness, to 130 mu m. The diameter of the vias is 40 mu m, and the pitch between the vias is 120 mu m. A liner filling approach was used to contact the TSV with the RDL on the backside of the Medipix3RX readout chip.
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  • Sarajlic, P, et al. (author)
  • Enhanced ventricular-arterial coupling during a 2-year physical activity programme in patients with rheumatoid arthritis : a prospective substudy of the physical activity in rheumatoid arthritis 2010 trial.
  • 2018
  • In: Journal of Internal Medicine. - : Wiley. - 0954-6820 .- 1365-2796. ; 284:6, s. 664-673
  • Journal article (peer-reviewed)abstract
    • OBJECTIVE: To establish how guided physical activity in patients with rheumatoid arthritis (RA) without known cardiovascular disease affected vascular and cardiac function, and how these two entities were prospectively interconnected in this patient group.METHODS: Prospective substudy of 29 participants in the Physical Activity in RA (PARA) 2010 trial. All subjects were examined at baseline, at year 1 and 2 with measures of pulse wave velocity and arterial augmentation index, as well as echocardiographic evaluation of diastolic parameters and ventricular-arterial coupling. Muscle strength and aerobic exercise capacity were assessed at baseline and yearly. All participants performed physiotherapist-guided aerobic and muscle strength exercise during 2 years and were reminded through SMS to report physical activity progress.RESULTS: This cohort of patients with RA exhibited increased vascular stiffness despite normal blood pressure. At baseline, lower muscle strength was associated with increased vascular stiffness (β = 0.68; P = 0.004), whereas lower aerobic working capacity was associated with left ventricular diastolic dysfunction (β = 0.85; P = 0.03). There was a significant positive correlation between vascular stiffness and diastolic dysfunction at baseline (R2  = 0.64) and for the changes in those parameters observed during 2 years of guided physical activity. Finally, a significant improvement in ventricular-arterial coupling was observed after exercise (P < 0.001).CONCLUSION: These results indicate that although differentially associated with physical capacity parameters, improved vascular stiffness and improved diastolic dysfunction are interrelated, and that an optimization of the ventricular-arterial coupling may contribute to the beneficial effects of physical activity in patients with RA.
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