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1.	Han, JM, et al. (author) Inhibition of colony stimulating factor-1 receptor (CSF-1R) as a potential therapeutic strategy for neurodegenerative diseases: opportunities and challenges 2022 In: Cellular and molecular life sciences : CMLS. - : Springer Science and Business Media LLC. - 1420-9071 .- 1420-682X. ; 79:4, s. 219- Journal article (peer-reviewed)abstract Microglia are specialized dynamic immune cells in the central nervous system (CNS) that plays a crucial role in brain homeostasis and in disease states. Persistent neuroinflammation is considered a hallmark of many neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson's disease (PD), Huntington’s disease (HD), amyotrophic lateral sclerosis (ALS) and primary progressive multiple sclerosis (MS). Colony stimulating factor 1-receptor (CSF-1R) is predominantly expressed on microglia and its expression is significantly increased in neurodegenerative diseases. Cumulative findings have indicated that CSF-1R inhibitors can have beneficial effects in preclinical neurodegenerative disease models. Research using CSF-1R inhibitors has now been extended into non-human primates and humans. This review article summarizes the most recent advances using CSF-1R inhibitors in different neurodegenerative conditions including AD, PD, HD, ALS and MS. Potential challenges for translating these findings into clinical practice are presented.
2.	Kara, FM, et al. (author) Adenosine A1 receptors (A1Rs) play a critical role in osteoclast formation and function 2010 In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. - : Wiley. - 1530-6860. ; 24:7, s. 2325-2333 Journal article (peer-reviewed)
3.	Tkach, AV, et al. (author) Graphene oxide, but not fullerenes, targets immunoproteasomes and suppresses antigen presentation by dendritic cells 2013 In: Small (Weinheim an der Bergstrasse, Germany). - : Wiley. - 1613-6829 .- 1613-6810. ; 9:9-10, s. 1686-1690 Journal article (peer-reviewed)
4.	2021 swepub:Mat__t
5.	2019 Journal article (peer-reviewed)

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Type of publication: journal article (4)

Type of content: peer-reviewed (4)

Author/Editor: Liu, X (1); Chen, L (1); Chen, S. (1); Clark, A. (1); Francis, D. (1); George, S. (1); show more...; Gupta, S. (1); Huang, Y. (1); King, M. (1); Lee, L. (1); Lewis, A. (1); Li, L. (1); Liu, B. (1); Lopes, L. (1); Losada, M. (1); Mann, A. (1); Mehta, A. (1); Moss, J. (1); Negri, G. (1); Robson, A. (1); Romano, M. (1); Thomson, E. (1); Wang, H. (1); Webb, S. (1); Wu, M. (1); Yang, Y. (1); Zhang, H. (1); Zhao, Z. (1); Morton, A. (1); Aoun, S. (1); Brown, G. (1); Patel, N. (1); Taylor, C. (1); Davies, E. (1); Haider, S. (1); Gupta, A. (1); Kelly, M. (1); Li, J. (1); Coe, P. (1); Smith, M. (1); Zhang, G (1); Pal, A. (1); Shaw, C. (1); Allen, K. (1); Price, S (1); Martin, J. (1); Thomas, P. (1); Davies, G (1); Schulz, J (1); Shurin, GV (1); show less...

University: Karolinska Institutet (5); University of Gothenburg (1); Uppsala University (1); Halmstad University (1); Stockholm University (1); Lund University (1); show more...; Chalmers University of Technology (1); show less...

Language: English (5)

Research subject (UKÄ/SCB): Medical and Health Sciences (2); Natural sciences (1)

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