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4.
  • Beecham, Ashley H, et al. (author)
  • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.
  • 2013
  • In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 45:11, s. 1353-60
  • Journal article (peer-reviewed)abstract
    • Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 potentially associated regions (P < 1.0 × 10(-4)). In a replication phase, we combined these data with previous genome-wide association study (GWAS) data from an independent 14,802 subjects with multiple sclerosis and 26,703 healthy controls. In these 80,094 individuals of European ancestry, we identified 48 new susceptibility variants (P < 5.0 × 10(-8)), 3 of which we found after conditioning on previously identified variants. Thus, there are now 110 established multiple sclerosis risk variants at 103 discrete loci outside of the major histocompatibility complex. With high-resolution Bayesian fine mapping, we identified five regions where one variant accounted for more than 50% of the posterior probability of association. This study enhances the catalog of multiple sclerosis risk variants and illustrates the value of fine mapping in the resolution of GWAS signals.
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5.
  • Schmidt, P.T., et al. (author)
  • Circulating ghrelin levels after food intake during different phases of the migrating motor complex in man.
  • 2006
  • In: European Journal of Clinical Investigation. - : Wiley. - 0014-2972 .- 1365-2362. ; 36:7, s. 503-509
  • Journal article (peer-reviewed)abstract
    • Background The timing of the migrating motor complexes (MMC) at food intake may influence gastric emptying and release of regulatory hormones. This report studies the relationships between phases I (motor quiescence) and II (intermediate frequency contractions) of MMC and prandial gut hormone response. Materials and methods Seven fasting volunteers ingested a meal during phase I or II of MMC verified by manometry, using paracetamol as a marker for gastric emptying. Blood was sampled before, during and 210 min after food intake for analysis of ghrelin, motilin, insulin and paracetamol. Results The basal level of ghrelin during phase I was 127·5 ± 25·4 pmol L-1 and during phase II was 132·4 ± 24·8 pmol L-1. After food intake during phase I, ghrelin fell to 77·2 ± 10 pmol L-1; in phase II it fell to 82·7 ± 17·8 pmol L-1 within 60 min and returned to baseline levels after 120 min. Baseline levels of motilin were 16 ± 2 pmol L-1 and 18 ± 3 pmol L-1 during phases I and II, respectively. After food, motilin decreased to 8·5 ± 0·7 pmol L-1 and 8·7 ± 1·0 pmol L-1 within 60 min and returned to baseline after 90 min. Insulin levels in phases I and II were 8·1 ± 1·2 mU L-1 and 8·6 ± 0·7 mU L-1, respectively, reaching 138·9 ± 35·6 mU L-1 and 167·4 ± 30·0 mU L-1 at 45 min postprandially. Conclusions The nutritional status of the gastrointestinal tract at food intake had only a limited impact on plasma ghrelin. After food intake, plasma ghrelin drops, similar to motilin, and resumes preprandial levels within 120 min.
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  • Wade, G. A., et al. (author)
  • The MiMeS survey of magnetism in massive stars : introduction and overview
  • 2016
  • In: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 456:1, s. 2-22
  • Journal article (other academic/artistic)abstract
    • The MiMeS (Magnetism in Massive Stars) project is a large-scale, high-resolution, sensitive spectropolarimetric investigation of the magnetic properties of O- and early B-type stars. Initiated in 2008 and completed in 2013, the project was supported by three Large Program allocations, as well as various programmes initiated by independent principal investigators, and archival resources. Ultimately, over 4800 circularly polarized spectra of 560 O and B stars were collected with the instruments ESPaDOnS (Echelle SpectroPolarimetric Device for the Observation of Stars) at the Canada-France-Hawaii Telescope, Narval at the Telescope Bernard Lyot and HARPSpol at the European Southern Observatory La Silla 3.6 m telescope, making MiMeS by far the largest systematic investigation of massive star magnetism ever undertaken. In this paper, the first in a series reporting the general results of the survey, we introduce the scientific motivation and goals, describe the sample of targets, review the instrumentation and observational techniques used, explain the exposure time calculation designed to provide sensitivity to surface dipole fields above approximately 100 G, discuss the polarimetric performance, stability and uncertainty of the instrumentation, and summarize the previous and forthcoming publications.
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  • Åström, E., et al. (author)
  • Precision measurements of linear scattering density using muon tomography
  • 2016
  • In: Journal of Instrumentation. - : Institute of Physics Publishing. - 1748-0221. ; 11:7
  • Journal article (peer-reviewed)abstract
    • We demonstrate that muon tomography can be used to precisely measure the properties of various materials. The materials which have been considered have been extracted from an experimental blast furnace, including carbon (coke) and iron oxides, for which measurements of the linear scattering density relative to the mass density have been performed with an absolute precision of 10%. We report the procedures that are used in order to obtain such precision, and a discussion is presented to address the expected performance of the technique when applied to heavier materials. The results we obtain do not depend on the specific type of material considered and therefore they can be extended to any application.
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  • Ahvenniemi, Esko, et al. (author)
  • Recommended reading list of early publications on atomic layer deposition-Outcome of the "Virtual Project on the History of ALD"
  • 2017
  • In: Journal of Vacuum Science & Technology. A. Vacuum, Surfaces, and Films. - : American Vacuum Society. - 0734-2101 .- 1520-8559. ; 35:1
  • Research review (peer-reviewed)abstract
    • Atomic layer deposition (ALD), a gas-phase thin film deposition technique based on repeated, self-terminating gas-solid reactions, has become the method of choice in semiconductor manufacturing and many other technological areas for depositing thin conformal inorganic material layers for various applications. ALD has been discovered and developed independently, at least twice, under different names: atomic layer epitaxy (ALE) and molecular layering. ALE, dating back to 1974 in Finland, has been commonly known as the origin of ALD, while work done since the 1960s in the Soviet Union under the name "molecular layering" (and sometimes other names) has remained much less known. The virtual project on the history of ALD (VPHA) is a volunteer-based effort with open participation, set up to make the early days of ALD more transparent. In VPHA, started in July 2013, the target is to list, read and comment on all early ALD academic and patent literature up to 1986. VPHA has resulted in two essays and several presentations at international conferences. This paper, based on a poster presentation at the 16th International Conference on Atomic Layer Deposition in Dublin, Ireland, 2016, presents a recommended reading list of early ALD publications, created collectively by the VPHA participants through voting. The list contains 22 publications from Finland, Japan, Soviet Union, United Kingdom, and United States. Up to now, a balanced overview regarding the early history of ALD has been missing; the current list is an attempt to remedy this deficiency.
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  • Danilchenko, Boris A., et al. (author)
  • High temperature Luttinger liquid conductivity in carbon nanotube bundles
  • 2010
  • In: Applied Physics Letters. - : American Institute of Physics. - 0003-6951 .- 1077-3118. ; 97:7, s. 072106-
  • Journal article (peer-reviewed)abstract
    • The conductance and the current-voltage characteristics of metallic single wall carbon nanotube bundles have been measured between 4.2 and 330 K using 10–30 ns electric pulses to avoid overheating. The current-voltage characteristics at different temperatures collapse to a single curve when plotted in the specific coordinates following from the Tomonaga–Luttinger (T–L) liquid concept. Direct evidence is obtained for the existence of a T–L liquid phase up to 190 K and the system shows a transition between the T–L liquid state and a Mott insulating phase below 25 K.
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  • Göransson, J., et al. (author)
  • Performance of a System for Rapid Phenotypic Antimicrobial Susceptibility Testing of Gram-Negative Bacteria Directly from Positive Blood Culture Bottles
  • 2023
  • In: Journal of Clinical Microbiology. - : American Society for Microbiology. - 0095-1137 .- 1098-660X. ; 61:3
  • Journal article (peer-reviewed)abstract
    • The rapid administration of optimal antimicrobial treatment is paramount for the treatment of bloodstream infections (BSIs), and rapid antimicrobial susceptibility testing (AST) results are essential. Q-linea has developed the ASTar system, a rapid phenotypic AST device. Here, we report the performance of the ASTar BC G- (Gram-negative) kit when assessed according to the ISO 20776-2:2007 standard for performance evaluation of in vitro diagnostic AST devices. The evaluated ASTar BC G- kit uses a broad panel of 23 antimicrobials for the treatment of BSIs caused by Gram-negative fastidious and nonfastidious bacteria across a range of 6 to 14 2-fold dilutions, including cefoxitin as a screening agent for AmpC-producing Enterobacterales. The ASTar system processes blood culture samples to generate data on MICs and susceptible, intermediate, or resistant (SIR) category. The automated protocol includes concentration determination and concentration adjustment to enable a controlled inoculum, followed by broth microdilution (BMD) and microscopy performed continuously to generate MIC values within approximately 6 h once the test is run on the ASTar system. The performance of the ASTar system was assessed against the ISO 20776-2:2007 standard BMD reference method. Testing was performed across three sites, with results from 412 contrived blood cultures and 74 fresh clinical blood cultures. The ASTar system was also tested for reproducibility, with triplicate testing of 11 strains. The accuracy study comprised 8,650 data points of bacterium-antimicrobial tests. The ASTar system demonstrated an overall essential agreement (EA) of 95.8% (8,283/8,650) and a categorical agreement (CA) of 97.6% (8,433/8,639) compared to the reference BMD method. The overall rate of major discrepancies (MDs) was 0.9% (62/6,845), and that of very major discrepancies (VMDs) was 2.4% (30/1,239). This study shows that the ASTar system delivers reproducible results with overall EA and CA of >95%.
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  • Hermansen, E. A. T., et al. (author)
  • Post-Paris policy relevance: lessons from the IPCC SR15 process
  • 2021
  • In: Climatic Change. - : Springer Science and Business Media LLC. - 0165-0009 .- 1573-1480. ; 169:1-2
  • Journal article (peer-reviewed)abstract
    • Policy relevance is the raison d'etre for the Intergovernmental Panel on Climate Change (IPCC), yet few studies have analysed what the concept entails, not least from the perspective of key target groups for the IPCC. We present a framework which enables analysis of how different actor strategies (heating up and cooling down) contribute to shape relevance-making in specific political situations when IPCC knowledge is interpreted and used. Drawing on empirical evidence from the reception and use of the Special Report on Global Warming of 1.5 degrees C (SR15) across three policy making levels, the paper demonstrates different examples of creating policy relevance. First, the paper analyses the origin of SR15 and the failed attempts to formally acknowledge SR15 in the United Nations Framework Convention on Climate Change (UNFCCC) process. Second, it investigates how SR15 has been used to develop and legitimize the EU net-zero target and the European Green Deal. Third, the paper demonstrates how SR15 has been used both for legitimizing and challenging climate policy at the national level, using the example of Norway. In sum, the reception of SR15 demonstrates that while IPCC outputs have resulted in controversy at the international level, they have been highly relevant at regional and national levels. The analysis shows that policy relevance is context-dependent and indirect-created through processes involving many actors, institutions, and types of knowledge. Situating these findings within the larger shift in the international climate regime implied by the Paris Agreement, the paper concludes with a set of empirically grounded recommendations for how the IPCC may approach the goal of policy relevance post-Paris.
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  • Jansson, S. -A, et al. (author)
  • Socioeconomic evaluation of well-characterized allergy to staple foods in adults
  • 2014
  • In: Allergy. European Journal of Allergy and Clinical Immunology. - : Wiley. - 0105-4538 .- 1398-9995. ; 69:9, s. 1241-1247
  • Journal article (peer-reviewed)abstract
    • Background: The aim of the present study was to evaluate if total, direct, indirect, and intangible costs differ between a cohort of adults with well-characterized allergy to staple foods ('cases') and controls. Methods: Swedish adults with objectively diagnosed food allergy to cow's milk, hen's egg, and/or wheat were recruited at an outpatient allergy clinic. Controls age- and sex-matched to cases were recruited from the same geographic area. For assessing the household costs of food allergy, a disease-specific socioeconomic questionnaire, developed within EuroPrevall, was utilized. Results: Overall annual total costs at the household level were significantly higher among adults with food allergy compared with controls (the difference amounted to 8164 (sic) ), whereas direct costs did not differ between cases and controls. However, household healthcare costs and costs for medicines were significantly higher for cases vs controls. Furthermore, indirect costs were significantly higher for households with food-allergic adults vs households without food-allergic adults. Specifically, more time was spent on performing domestic tasks due to a family member's food-allergy-related illness, as well as shopping and preparing food, and seeking food-allergy-related information. Presence of food allergy also affected intangible costs. Adults with food allergy experienced overall lower health status compared with controls. Conclusions: Swedish adults with allergy to staple foods have higher total costs determined as direct, indirect, and intangible costs using the disease-specific socioeconomic questionnaire. Thus, total costs were 8164 (sic) higher per year in households with at least one adult allergic to staple foods compared with controls.
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  • Kristensson, E, et al. (author)
  • Acute psychological stress raises plasma ghrelin in the rat.
  • 2006
  • In: Regulatory Peptides. - : Elsevier BV. - 0167-0115 .- 1873-1686. ; 134:2-3, s. 114-117
  • Journal article (peer-reviewed)abstract
    • Ghrelin is produced by the A-like cells of the stomach and mobilized by food deprivation. It was reported recently that acute psychological stress increases ghrelin gene expression in rat oxyntic mucosa. The aim of this study was to examine the effect of such stress on circulating ghrelin levels. To this end, we measured plasma ghrelin in Wistar Kyoto (WKY) rats (a high-anxiety strain) and Sprague–Dawley (SPD) rats (a low-anxiety strain), exposed to water avoidance stress for 60 min. Blood was collected before and after the stress. Acute stress increased the plasma ACTH concentration not, vert, similar5-fold (p < 0.01) in both strains of rats, while plasma ghrelin increased by 85% (p < 0.01) in the SPD rats and by 40% (p < 0.001) in the WKY rats. Ghrelin levels after acute stress were higher (p < 0.05) in the SPD rats than in the WKY rats. Sham stress did not affect plasma ghrelin. We conclude that acute psychological stress mobilizes ghrelin and that the SPD rats respond with a higher plasma ghrelin concentration than the WKY rats.
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  • Protudjer, J. L. P., et al. (author)
  • Health-related quality of life in children with objectively diagnosed staple food allergy assessed with a disease-specific questionnaire
  • 2015
  • In: Acta Paediatrica. - : Wiley. - 0803-5253 .- 1651-2227. ; 104:10, s. 1047-1054
  • Journal article (peer-reviewed)abstract
    • Aim: Among Swedish children of 0-12 years old, we investigated various food allergy-related exposures associated with health-related quality of life using a food allergy-specific questionnaire among children allergic to the staple foods cow's milk, hen's egg and/or wheat, and contextualised worse food allergy-associated health-related quality of life using a generic questionnaire versus controls. Methods: In total, 85 children with objectively diagnosed allergy to the staple foods were included as cases, and 94 children matched for age and sex were included as controls. We administered a food allergy-specific parent-completed questionnaire originally developed by EuroPrevall to cases only, and a generic health-related quality of life questionnaire (EuroQol Health Questionnaire, 5 Dimensions; EQ 5-D); to both cases and controls. Results: Hen's egg was the most common offending staple food, affecting 76% of cases. Approximately 7% of cases were allergic to all three staple foods. Parent-reported respiratory and cardiovascular symptoms were associated with worse health-related quality of life. Elements of disease severity [previous anaphylaxis (p < 0.001); epinephrine autoinjector prescription (p < 0.003)] were negatively associated with health-related quality of life. Cases had worse health-related quality of life measured by the EQ-5D compared to controls (p < 0.01). Conclusion: The use of a disease-specific questionnaire revealed that disease severity in children with objectively diagnosed allergy to the staple foods cow's milk, hen's egg and/or wheat is associated with worse health-related quality of life. The use of a generic questionnaire confirmed that cases have worse health-related quality of life than controls.
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  • Sawcer, Stephen, et al. (author)
  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
  • 2011
  • In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 476:7359, s. 214-219
  • Journal article (peer-reviewed)abstract
    • Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and neurodegenerative processes typically results in intermittent neurological disturbance followed by progressive accumulation of disability. Epidemiological studies have shown that genetic factors are primarily responsible for the substantially increased frequency of the disease seen in the relatives of affected individuals, and systematic attempts to identify linkage in multiplex families have confirmed that variation within the major histocompatibility complex (MHC) exerts the greatest individual effect on risk. Modestly powered genome-wide association studies (GWAS) have enabled more than 20 additional risk loci to be identified and have shown that multiple variants exerting modest individual effects have a key role in disease susceptibility. Most of the genetic architecture underlying susceptibility to the disease remains to be defined and is anticipated to require the analysis of sample sizes that are beyond the numbers currently available to individual research groups. In a collaborative GWAS involving 9,772 cases of European descent collected by 23 research groups working in 15 different countries, we have replicated almost all of the previously suggested associations and identified at least a further 29 novel susceptibility loci. Within the MHC we have refined the identity of the HLA-DRB1 risk alleles and confirmed that variation in the HLA-A gene underlies the independent protective effect attributable to the class I region. Immunologically relevant genes are significantly overrepresented among those mapping close to the identified loci and particularly implicate T-helper-cell differentiation in the pathogenesis of multiple sclerosis.
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  • Schön, Thomas, et al. (author)
  • Effects of a food supplement rich in arginine in patients with smear positive pulmonary tuberculosis - A randomised trial
  • 2011
  • In: Tuberculosis. - : Elsevier. - 1472-9792 .- 1873-281X. ; 91:5, s. 370-377
  • Journal article (peer-reviewed)abstract
    • In tuberculosis (TB), the production of nitric oxide (NO) is confirmed but its importance in host defense is debated. Our aim was to investigate whether a food supplement rich in arginine could enhance clinical improvement in TB patients by increased NO production. Smear positive TB patients from Gondar, Ethiopia (n = 180) were randomized to a food supplementation rich in arginine (peanuts, equivalent to 1 g of arginine/day) or with a low arginine content (wheat crackers, locally called daboqolo) during four weeks. The primary outcome was cure rate according to the WHO classification and secondary outcomes were sputum smear conversion, weight gain, sedimentation rate, reduction of cough and chest X-ray improvement as well as levels of NO in urine (uNO) or exhaled air (eNO) at two months. There was no effect of the intervention on the primary outcome (OR 1.44, 95% CI: 0.69-3.0, p = 0.39) or secondary outcomes. In the subgroup analysis according to HIV status, peanut supplemented HIV+/TB patients showed increased cure rate (83.8% (31/37) vs 53.1% (17/32), p andlt; 0.01). A low baseline eNO (andlt; 10 ppb) in HIV+/TB patients was associated with a decreased cure rate. We conclude that nutritional supplementation with a food supplement rich in arginine did not have any overall clinical effect. In the subgroup of HIV positive TB patients, it significantly increased the cure rate and as an additional finding in this subgroup, low initial levels of NO in exhaled air were associated with a poor clinical outcome but this needs to be confirmed in further studies.
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  • Sundqvist, Hanna S., et al. (author)
  • Arctic Holocene proxy climate database - new approaches to assessing geochronological accuracy and encoding climate variables
  • 2014
  • In: Climate of the Past. - : Copernicus GmbH. - 1814-9324 .- 1814-9332. ; 10:4, s. 1605-1631
  • Journal article (peer-reviewed)abstract
    • We present a systematic compilation of previously published Holocene proxy climate records from the Arctic. We identified 170 sites from north of 58 degrees N latitude where proxy time series extend back at least to 6 cal ka (all ages in this article are in calendar years before present - BP), are resolved at submillennial scale (at least one value every 400 +/- 200 years) and have age models constrained by at least one age every 3000 years. In addition to conventional meta-data for each proxy record (location, proxy type, reference), we include two novel parameters that add functionality to the database. First, climate interpretation is a series of fields that logically describe the specific climate variable(s) represented by the proxy record. It encodes the proxy-climate relation reported by authors of the original studies into a structured format to facilitate comparison with climate model outputs. Second, geochronology accuracy score (chron score) is a numerical rating that reflects the overall accuracy of C-14-based age models from lake and marine sediments. Chron scores were calculated using the original author-reported C-14 ages, which are included in this database. The database contains 320 records (some sites include multiple records) from six regions covering the circumpolar Arctic: Fennoscandia is the most densely sampled region (31% of the records), whereas only five records from the Russian Arctic met the criteria for inclusion. The database contains proxy records from lake sediment (60 %), marine sediment (32 %), glacier ice (5 %), and other sources. Most (61 %) reflect temperature (mainly summer warmth) and are primarily based on pollen, chironomid, or diatom assemblages. Many (15 %) reflect some aspect of hydroclimate as inferred from changes in stable isotopes, pollen and diatom assemblages, humification index in peat, and changes in equilibrium-line altitude of glaciers. This comprehensive database can be used in future studies to investigate the spatio-temporal pattern of Arctic Holocene climate changes and their causes. The Arctic Holocene data set is available from NOAA Paleoclimatology.
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  • Aleksandrovskii, A. N., et al. (author)
  • Low-temperature thermal expansion of pure and inert gas-doped fullerite C60
  • 2003
  • In: Fizika Nizkikh Temperatur (Kharkov). - : AIP Publishing. - 0132-6414 .- 1816-0328. ; 29:4, s. 432-442
  • Journal article (peer-reviewed)abstract
    • The low temperature (2–24 K) thermal expansion of pure (single-crystal and polycrystalline) C60 and polycrystalline C60 intercalated with He, Ne, Ar, and Kr has been investigated using the high-resolution capacitance dilatometer. The investigation of the time dependence of the sample length variations deltaL(t) on heating by deltaT shows that the thermal expansion is determined by the sum of positive and negative contributions, which have different relaxation times. The negative thermal expansion usually prevails at helium temperatures. The positive expansion is connected with the phonon thermalization of the system. The negative expansion is caused by reorientation of the C60 molecules. It is assumed that the reorientation is of a quantum character. The inert gas impurities affect the reorientation of the C60 molecules very strongly, especially at liquid helium temperatures. A temperature hysteresis of the thermal expansion coefficient of Kr– and He–C60 solutions has been revealed. The hysteresis is attributed to orientational polyamorphous transformation in these systems.
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  • Aleksandrovskii, A.N., et al. (author)
  • On the polyamorphism of fullerite-based orientational glasses.
  • 2005
  • In: Low Temperature Physics. - : AIP Publishing. - 1063-777X .- 1090-6517. ; 31:5, s. 429-444
  • Journal article (peer-reviewed)abstract
    • The dilatometric investigation in the temperature range of 2–28 K shows that a first-orderpolyamorphous transition occurs in the orientational glasses based on C60 doped with H2, D2 andXe. A polyamorphous transition was also detected in C60 doped with Kr and He. It is observed thatthe hysteresis of thermal expansion caused by the polyamorphous transition (and, hence, the transitiontemperature) is essentially dependent on the type of doping gas. Both positive and negativecontributions to the thermal expansion were observed in the low-temperature phase of the glasses.The relaxation time of the negative contribution occurs to be much longer than that of the positivecontribution. The positive contribution is found to be due to phonon and libron modes, whilst thenegative contribution is attributed to tunneling states of the C60 molecules. The characteristictime of the phase transformation from the low-T phase to the high-T phase has been found for theC60–H2 system at 12 K. A theoretical model is proposed to interpret these observed phenomena.The theoretical model proposed, includes a consideration of the nature of polyamorphism inglasses, as well as the thermodynamics and kinetics of the transition. A model of noninteractingtunneling states is used to explain the negative contribution to the thermal expansion. The experimentaldata obtained is considered within the framework of the theoretical model. From the theoreticalmodel the order of magnitude of the polyamorphous transition temperature has been estimated.It is found that the late stage of the polyamorphous transformation is described well by theKolmogorov law with an exponent of n = 1. At this stage of the transformation, the two-dimensionalphase boundary moves along the normal, and the nucleation is not important.
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  • Andersson, Britt M., et al. (author)
  • Electrical resistivity and critical temperature of Bi-based high-Tc superconductors to 1 GPa
  • 1990
  • In: High Pressure Research, volumes 3 to 5. - London : Gordon and Breach. - 2881247466 ; 3:1-6, s. 120-122
  • Conference paper (peer-reviewed)abstract
    • We have measured the electrical resistance R of a sintered, two-phase, high-TC superconductor with the nominal composition BiSrCaCu2Ox, as a function of T and p. We find d(lnR)/dp ≃ -0.06 GPa-1 at 295 K, while dTC/dp is 2.5 K/GPa for the phase with Tc ≃ 76 and 2 K/GPa for that with TC ≃ 106 K.
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  • Andersson, Odd E., et al. (author)
  • A study of temperature and pressure induced structural and electronic changes in SbCl5 intercalated graphite : Part II. Experimental data for c-axis resistivity
  • 1992
  • In: Journal of Materials Research. - 0884-2914 .- 2044-5326. ; 7:11, s. 2989-3000
  • Journal article (peer-reviewed)abstract
    • We present experimental data for the c-axis resistivity ?c of stage s = 2, 3, 4, 5, and 8, SbCl5 intercalated graphite, over the temperature range 40 to 300 K and the pressure range 0 to 0.8 GPa (0–8 kbar). For most specimens studied, resistance anomalies are observed below 230 K at atmospheric pressure and at pressures up to 0.5 GPa at 293 K. These anomalies are explained in terms of structural changes from a disordered or partly crystallized in-plane intercalate structure at atmospheric pressure and T > 230 K to an almost completely crystallized structure below this temperature, or at elevated pressures, as discussed in a companion paper. In the crystallized phases ?c is approximately linear in T except for stage 8, for which a nonlinear behavior, with a negative temperature coefficient of resistivity below 200 K, is observed. The results are compared with previously available literature data, and the p-T phase diagram is briefly discussed.
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  • Andersson, Odd E., et al. (author)
  • A study of temperature and pressure induced structural and electronic changes in SbCl5 intercalated graphite : Part IV: Basal plane resistivity
  • 1995
  • In: Journal of Materials Research. - 0884-2914 .- 2044-5326. ; 10:7, s. 1653-1660
  • Journal article (peer-reviewed)abstract
    • Using an inductive technique, we have measured the in-plane resistivity rhoa of stages 2, 4, 5, and 8 SbCl5-GIC's versus temperature T and pressure p in the ranges 130–300 K and 0–0.85 GPa. The room temperature values of rhoa range from 4.0 µOcm for the stages 5 sample to 7.7 µOcm for the stage 8 sample. At all pressures, rhoa shows a metallic temperature dependence rhoa ~ Ta, with 1 < a < 2, but in contrast to the c-axis resistivity rhoc, it depends only very weakly on pressure and/or intercalate structural order. We show that the behavior observed is consistent with a band conduction model.
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  • Andersson, Odd E., et al. (author)
  • C-axis resistance of HgCl2 intercalated graphite as a function of temperature and pressure
  • 1989
  • In: Synthetic Metals volume 34. - Lausanne : Elsevier Sequoia SA. ; , s. 485-490
  • Conference paper (peer-reviewed)abstract
    • The c-axis resistance of stage 3 HgCl2 intercalated graphite has been measured as a function of temperature T and pressure p in the range 40 to 300 K and up to 1 GPa (10 kbar). The absolute resistivity and its T- and p- dependence are all in good agreement with data for other acceptor compounds. The measurements show that a previosly unknown phase transformation occurs above 0.4 GPa. Below 250 K the high pressure phase is metastable down to zero pressure, and an x-ray diffraction analysis of metastable material shows that no stage change occurs. The transition thus probably leads to a different in-plane structure characterized by a more densely packed intercalate layer.
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  • Andersson, Odd E., et al. (author)
  • Low temperature calibration of Manganin pressure gauges
  • 1997
  • In: Review of Scientific Instruments. - : AIP Publishing. - 0034-6748 .- 1089-7623. ; 68:2, s. 1344-1345
  • Journal article (peer-reviewed)abstract
    • High pressures are often measured using the resistance of Manganin wires. However, the pressure coefficient of resistance is known to depend on temperature. We have measured this temperature dependence by comparing the output from a Manganin gauge with that of a well calibrated Zeranin gauge and determined a correction factor which enables us to measure the pressure at any temperature between 150 and 300 K with a temperature dependent error well below 0.5%.
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  • Andersson, Odd E., et al. (author)
  • Pressure-induced modifications of structural and transport properties in SbCl5 intercalated graphite
  • 1992
  • In: Materials Science Forum volumes 91-93, Part I. - Zürich : Trans Tech Publications. - 0878496394 ; , s. 301-306
  • Conference paper (peer-reviewed)abstract
    • The structure and the c-axis resistivity of SbCl5 intercalated graphite have been studied as functions of T and p, over the ranges 40 to 295 K and 0 to 0.7 GPa. Slow cooling or slow application of pressure p > 0.4 GPa lead to states of complete but different crystallization of the intercalate, but after rapid cooling or pressurization any crystallization is incomplete. The resistivity of the high pressure crystallized phase is about 50% lower than that of the low T, low p phase under identical p-T conditions. No significant difference is seen between the behaviour of HOPG-based and single crystal based materials.
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32.
  • Andersson, Odd E., et al. (author)
  • Structure, c-axis resistivity, and p-T phase diagram of SbCl5 intercalated graphite
  • 1989
  • In: Synthetic Metals volume 34. - Lausanne : Elsevier Sequoia SA. ; , s. 187-192
  • Conference paper (peer-reviewed)abstract
    • Experimental data are reported for the c-axis resistivity varrhoc of stages n = 3,4,5 and 8 SbCl5 intercalated graphite as a function of T and p, in the range 40 – 300 K and 0-0.5 GPa (5 kbar). varrhoc varied in a systematic way with p, T, and n. Well ordered low-T phases were obtained for all stages; disordering at 200 – 235 K gave rise to well defined multiple anomalies in varrhoc. We also report x-ray diffraction data on the stage 2 compound: evidence was found for large variations in the in-plane structure even for nominally identical samples.
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33.
  • Andersson, Odd E., et al. (author)
  • The c-axis resistivity for two HOPG-based, first stage CuAl2Cl8 and second stage CuCl2 - graphite intercalation compounds as a function of both pressure and temperature
  • 1996
  • In: Journal of Physics and Chemistry of Solids, volume 57, issues 6-8. - : Elsevier Ltd.. ; , s. 719-723
  • Conference paper (peer-reviewed)abstract
    • In this paper we present data for the c-axis resistivity of first stage CuAl2Cl8 GIC and second stage CuCl2 GIC as functions of pressure, p, (0.0 < p < 1.5 GPa) and of temperature, T, (4 < T < 300 K). We show evidence of a possible new high-pressure phase above 1.0 GPa for the CuAl2Cl8 GIC and we show that the CuCl2 GIC is very stable at all pressures and temperature investigated. We make a comparison with previous results on SbCl5 GICs and other chloride intercalation compounds and with theories treating the temperature and pressure coefficients of transport parameters in layered solids.
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34.
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35.
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36.
  • Asayama, Shinichiro, et al. (author)
  • Three institutional pathways to envision the future of the IPCC
  • 2023
  • In: Nature Climate Change. - : Nature Portfolio. - 1758-678X .- 1758-6798. ; 13:9, s. 877-880
  • Journal article (peer-reviewed)abstract
    • The IPCC has been successful at building its scientific authority, but it will require institutional reform for staying relevant to new and changing political contexts. Exploring a range of alternative future pathways for the IPCC can help guide crucial decisions about redefining its purpose.
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37.
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38.
  • Barrio, Isabel C., et al. (author)
  • Background invertebrate herbivory on dwarf birch (Betula glandulosa-nana complex) increases with temperature and precipitation across the tundra biome
  • 2017
  • In: Polar Biology. - : Springer. - 0722-4060 .- 1432-2056. ; 40:11, s. 2265-2278
  • Journal article (peer-reviewed)abstract
    • Chronic, low intensity herbivory by invertebrates, termed background herbivory, has been understudied in tundra, yet its impacts are likely to increase in a warmer Arctic. The magnitude of these changes is however hard to predict as we know little about the drivers of current levels of invertebrate herbivory in tundra. We assessed the intensity of invertebrate herbivory on a common tundra plant, the dwarf birch (Betula glandulosa-nana complex), and investigated its relationship to latitude and climate across the tundra biome. Leaf damage by defoliating, mining and gall-forming invertebrates was measured in samples collected from 192 sites at 56 locations. Our results indicate that invertebrate herbivory is nearly ubiquitous across the tundra biome but occurs at low intensity. On average, invertebrates damaged 11.2% of the leaves and removed 1.4% of total leaf area. The damage was mainly caused by external leaf feeders, and most damaged leaves were only slightly affected (12% leaf area lost). Foliar damage was consistently positively correlated with mid-summer (July) temperature and, to a lesser extent, precipitation in the year of data collection, irrespective of latitude. Our models predict that, on average, foliar losses to invertebrates on dwarf birch are likely to increase by 6-7% over the current levels with a 1 degrees C increase in summer temperatures. Our results show that invertebrate herbivory on dwarf birch is small in magnitude but given its prevalence and dependence on climatic variables, background invertebrate herbivory should be included in predictions of climate change impacts on tundra ecosystems.
  •  
39.
  •  
40.
  • Berg, J, et al. (author)
  • Crater formation in Langmuir-Blodgett films induced by electronic sputtering with fast heavy ions
  • 1987
  • In: Applied Physics Letters. - 0003-6951 .- 1077-3118. ; 51:17, s. 1379-
  • Journal article (peer-reviewed)abstract
    • Secondary ion formation by fast heavy ion impact (electronic sputtering) on Langmuir–Blodgett films of fatty acids has been studied. The results show unambiguously that molecular ions originate from molecules in layers other than the surface layer. Furthermore, the results indicate that craters may be formed in electronic sputtering of such films. The depth of the craters depends on the stopping power of the incident ion and lower limits of the order of 100–200 Å are obtained from the ion data.
  •  
41.
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42.
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43.
  • Borrega, M., et al. (author)
  • Utilizing and Valorizing Oat and Barley Straw as an Alternative Source of Lignocellulosic Fibers
  • 2022
  • In: Materials. - : MDPI AG. - 1996-1944. ; 15:21
  • Journal article (peer-reviewed)abstract
    • The transition to sustainable, biodegradable, and recyclable materials requires new sources of cellulose fibers that are already used in large volumes by forest industries. Oat and barley straws provide interesting alternatives to wood fibers in lightweight material applications because of their similar chemical composition. Here we investigate processing and material forming concepts, which would enable strong fiber network structures for various applications. The idea is to apply mild pretreatment processing that could be distributed locally so that the logistics of the raw material collection could be made efficient. The actual material production would then combine foam-forming and hot-pressing operations that allow using all fractions of fiber materials with minimal waste. We aimed to study the technical features of this type of processing on a laboratory scale. The homogeneity of the sheet samples was very much affected by whether the raw material was mechanically refined or not. Straw fibers did not form a bond spontaneously with one another after drying the sheets, but their effective bonding required a subsequent hot pressing operation. The mechanical properties of the formed materials were at a similar level as those of the conventional wood-fiber webs. In addition to the technical aspects of materials, we also discuss the business opportunities and system-level requirements of using straw as an alternative source of lignocellulosic fibers. 
  •  
44.
  • Cato, Ingemar, et al. (author)
  • DIOXINS AND OTHER POPS IN THE BALTIC SEA – TRENDS AND CURRENT
  • 2009
  • In: 29th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin 2009) in Bejing, China, August 25-30, 2009.
  • Conference paper (peer-reviewed)abstract
    • This paper summarizes a project that was initiated by the Swedish Environmental Protection Agency (EPA) in 2006. It involved several field studies and fate model calculations with the aim to better understand the present contamination situation of dioxins and other persistent organic pollutants (POPs) in the Baltic Sea region. Atmospheric inputs were found to be the dominant external source for all of the selected POPs (dioxins, PCBs and HCB). The model also predicted a significant decline of POP-levels in Baltic surface water if atmospheric concentrations are reduced. This issue is highly prioritized by the Swedish EPA since TEQ-levels of fatty fish exceed maximum residue limits set by the EU. Dioxin source regions were identified by air measurements and analysis of air mass origin. It was found that air that had passed over the European continent contained the highest concentrations, and the congener composition indicated that several major sources types may exist. This research has high relevance for the Swedish EPA, and continued efforts for resolving the dioxin issue of the Baltic Sea will follow.
  •  
45.
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46.
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47.
  •  
48.
  •  
49.
  • Danilchenko, Boris A., et al. (author)
  • Stability of the Tomonaga-Luttinger liquid state in gamma-irradiated carbon nanotube bundles
  • 2013
  • In: Journal of Physics. - : Institute of Physics Publishing (IOPP). - 0953-8984 .- 1361-648X. ; 25:47, s. 475302-
  • Journal article (peer-reviewed)abstract
    • We report experimental results for the changes in conductivity of single-wall carbon nanotube bundles when irradiated by Co-60 gamma-rays in various environments. In the current study the samples investigated were irradiated in hermetic cells, either evacuated (0.1 Pa) or filled with hydrogen or deuterium at atmospheric pressure. In situ measurements of the resistance change as a function of irradiation dose at room temperature are presented. It was found that, for all irradiation conditions, the normalized resistance versus irradiation dose demonstrates a logarithmic behaviour. A phenomenological model for the observed dependence is derived. The current-voltage characteristics of the irradiated samples were measured in the temperature range from 4.5 to 300 K using short (10 ns) electric pulses, and the results demonstrate a scaling behaviour. This scaling occurs in the universal coordinates that correspond to the Tomonaga-Luttinger liquid concept. Our results confirm the existence of the Tomonaga-Luttinger liquid phase up to room temperature in carbon nanotubes after gamma-irradiation to a dose of 5 x10(7) rad in vacuum, 1 : 7 x 10(7) rad in hydrogen and 1 : 24 x 10(8) rad in deuterium.
  •  
50.
  • Diederichs, J., et al. (author)
  • Critical currents in Tl-2122 and Y-124 sinters under high hydrostatic pressure
  • 1991
  • In: Superconductor Science and Technology, volume 4, Special Issue 1S. - Bristol : Adam Hilger. - 0750301082 ; , s. S97-S99
  • Conference paper (peer-reviewed)abstract
    • Utilizing AC susceptibility measurements the authors have investigated the inter and intragranular properties of selected bulk materials under hydrostatic pressures to 3.5 GPa. A single phase Tl2CaBa2Cu2O8 sample with superconducting transition temperature Tc approximately=107 K shows a clear maximum in Tc(P) at approximately 2.2 GPa coupled with a nearly twofold increase to 3 GPa of the intergranular critical current density JcJ near Tc. The second sample, a YBa2Cu4O8 sinter, shows a large linear increase in Tc with pressure (+5.5 K/GPa) as well as a fivefold increase JcJ to 3 GPa. Applying a critical state model, the authors find that Tc(P) varies as lambda g-2(P), where lambda g is the intragranular (London) penetration depth.
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