| 1. |
- Brante, Thomas, et al.
(author)
-
Inledning
- 2019
-
In: Det professionella landskapets framväxt. - 9789144122052 ; , s. 17-54
-
Book chapter (peer-reviewed)
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| 2. |
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| 3. |
- Johnsson, Eva, et al.
(author)
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Den psykosociala integrationens fält.
- 2019
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In: Det professionella landskapets framväxt. - 9789144122052 ; , s. 261-331
-
Book chapter (other academic/artistic)
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| 4. |
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| 5. |
- Lundh, Christer, et al.
(author)
-
Regional Wages in Sweden 1860-1914
- 2004
-
In: Wage Formation, Labour Market Institutions and Economic Transformation in Sweden 1860-2000. ; 32
-
Book chapter (other academic/artistic)
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| 6. |
- Svensson, Kerstin, et al.
(author)
-
Den sociala regleringens fält
- 2019
-
In: Det professionella landskapets framväxt. - 9789144122052 ; , s. 209-260
-
Book chapter (other academic/artistic)
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| 7. |
- Svensson, Kerstin, et al.
(author)
-
Den sociala regleringens professioner
- 2019
-
In: Ett professionellt landskap i förvandling. - 9789144122274 ; , s. 171-216
-
Book chapter (other academic/artistic)
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| 8. |
- Almqvist, Erik, et al.
(author)
-
Increased plasma concentrations of N-terminal pro-B-type natriuretic peptide in patients with mild primary hyperparathyroidism.
- 2006
-
In: Clinical endocrinology. - : Wiley. - 0300-0664 .- 1365-2265. ; 65:6, s. 760-6
-
Journal article (peer-reviewed)abstract
- OBJECTIVE: Primary hyperparathyroidism (PHPT) is associated with heart disease. The aims of the present study were to evaluate how cardiac function and secretion of N-terminal pro-B-type natriuretic peptide (NT-proBNP) correlate in patients with mild PHPT, and how the plasma level of NT-proBNP is influenced by cure of the parathyroid disease. DESIGN AND PATIENTS: Forty-two patients with PHPT without symptoms of heart disease were examined before and 1 year after curative parathyroidectomy. MEASUREMENTS: Plasma or serum concentrations of NT-proBNP, calcium, PTH, creatinine, oestradiol, testosterone and SHBG were measured. Cardiac function was evaluated by equilibrium radionuclide angiography (ERNA). RESULTS: At baseline, NT-proBNP levels correlated negatively with systolic function [left ventricular ejection fraction (LVEF), P < 0.001]. Twelve per cent of the patients had NT-proBNP levels above normal reference values preoperatively. One year postoperatively, the corresponding proportion was 21%. The mean plasma concentration of NT-proBNP increased after parathyroidectomy (P < 0.01) in parallel with a dip in diastolic function (peak filling rate, P < 0.05) and a falling trend in systolic function (LVEF, P = 0.08). The postoperative percentage changes in circulating NT-proBNP and total oestradiol correlated positively (P < 0.05). CONCLUSIONS: Patients with mild PHPT and normal renal function may have high levels of circulating NT-proBNP despite the absence of symptomatic heart disease. Cure of the parathyroid disease is followed by a further increase in NT-proBNP secretion in parallel with ERNA measures, indicating subclinical changes in heart function. These results are in line with data indicating an association between PHPT and increased risk of premature death.
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| 9. |
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| 10. |
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| 11. |
- Andrén, Lennart, 1946, et al.
(author)
-
Ketanserin in hypertension. Early clinical evaluation and dose finding study of a new 5-HT2 receptor antagonist.
- 1983
-
In: Acta medica Scandinavica. - 0001-6101. ; 214:2, s. 125-30
-
Journal article (peer-reviewed)abstract
- Ketanserin, a new 5-hydroxy-tryptamine antagonist, was given at three different dosage levels (double-blind, randomized) in a dose finding study for 2 months to 31 patients with mild to moderately severe essential hypertension. Treatment with ketanserin was then continued until 9 months had been completed. A significant antihypertensive effect was demonstrated at daily dosages of 20 mg t.i.d. or 40 mg t.i.d. The antihypertensive effect was similar to that of previous multiple drug treatment with conventional drugs. However, 60 mg t.i.d. was not acceptable, at least not as initial dosage. At this dose level, 8 out of 10 patients had to be withdrawn from the study during the initial phase due to unwanted effects. It is conceivable that alpha 1-adrenoceptor blockade may have played a role at this dose level, since postural reactions were observed which was otherwise not the case during this study. Ketanserin is a new and interesting alternative in the treatment of hypertension. At the same time it offers a tool by which the role of 5-hydroxy-tryptamine in the regulation of arterial pressure can be investigated.
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| 12. |
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| 13. |
- Axelsson, Robert, et al.
(author)
-
Evaluation of Multi-level Social Learning for Sustainable Landscapes : Perspective of a Development Initiative in Bergslagen, Sweden
- 2013
-
In: Ambio. - : Springer Netherlands. - 0044-7447 .- 1654-7209. ; 42:2, s. 241-253
-
Journal article (peer-reviewed)abstract
- To implement policies about sustainable landscapes and rural development necessitates social learning about states and trends of sustainability indicators, norms that define sustainability, and adaptive multi-level governance. We evaluate the extent to which social learning at multiple governance levels for sustainable landscapes occur in 18 local development initiatives in the network of Sustainable Bergslagen in Sweden. We mapped activities over time, and interviewed key actors in the network about social learning. While activities resulted in exchange of experiences and some local solutions, a major challenge was to secure systematic social learning and make new knowledge explicit at multiple levels. None of the development initiatives used a systematic approach to secure social learning, and sustainability assessments were not made systematically. We discuss how social learning can be improved, and how a learning network of development initiatives could be realized.
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| 14. |
- Bergström, Staffan, et al.
(author)
-
Development and application of an analytical protocol for evaluation of treatment processes for landfill leachates : I. Development of an analytical protocol for handling organic compounds in complex leachate samples
- 2007
-
In: International Journal of Environmental Analytical Chemistry. - 0306-7319 .- 1029-0397. - 0306-7319 ; 87:1, s. 1-15
-
Journal article (peer-reviewed)abstract
- A strategy is presented for evaluation of treatment procedures for landfill leachate with emphasis on organic pollutants. An analytical scheme, the LAQUA protocol, was developed as a guide for the analytical work. The protocol includes organic as well as metals,. inorganic ions, water-quality parameters, and toxicity. The proposed strategy considers the behaviour of both polar and non-polar organic substances at trace levels. For polar substances, phenols were chosen as markers and determined with an automated supported liquid membrane extraction device, coupled on-line to HPLC with a diode-array detector. For non-polar substances, PCBs and 10 unidentified compounds were chosen as markers and analysed by solid-phase extraction combined with supercritical fluid extraction with GC analysis. The chosen measurement strategy, based on the use of marker substances, difference measurements, and versatile data-handling procedures, provided essential information about complex systems at relatively low cost.
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| 15. |
- Bergström, Staffan, et al.
(author)
-
Development and application of an analytical protocol for evaluation of treatment processes for landfill leachates. I. Development of an analytical protocol for handling organic compounds in complex leachate samples
- 2007
-
In: International Journal of Environmental Analytical Chemistry. - : Informa UK Limited. - 1029-0397 .- 0306-7319. ; 87:1, s. 1-15
-
Journal article (peer-reviewed)abstract
- A strategy is presented for evaluation of treatment procedures for landfill leachate with emphasis on organic pollutants. An analytical scheme, the LAQUA protocol, was developed as a guide for the analytical work. The protocol includes organic as well as metals,. inorganic ions, water-quality parameters, and toxicity. The proposed strategy considers the behaviour of both polar and non-polar organic substances at trace levels. For polar substances, phenols were chosen as markers and determined with an automated supported liquid membrane extraction device, coupled on-line to HPLC with a diode-array detector. For non-polar substances, PCBs and 10 unidentified compounds were chosen as markers and analysed by solid-phase extraction combined with supercritical fluid extraction with GC analysis. The chosen measurement strategy, based on the use of marker substances, difference measurements, and versatile data-handling procedures, provided essential information about complex systems at relatively low cost.
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| 16. |
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| 17. |
- Crouse, David F., et al.
(author)
-
The Set MHT
- 2011
-
In: 14th International Conference on Information Fusion, Fusion 2011; Chicago, IL; 5 July 2011 through 8 July 2011. - 9781457702679
-
Conference paper (peer-reviewed)abstract
- Abstract—We introduce the Set MHT, a tracking algorithmthat maintains multiple hypotheses and produces “smooth”estimates without the track coalescence often associated withMinimum Mean Squared Error (MMSE) estimation or thejitter associated with Maximum Likelihood (ML) estimation.It does this by utilizing Minimum Mean Optimal SubpatternAssignment (MMOSPA) estimation techniques coupled with atheoretically-grounded approach for probabilistically determiningthe identities of the state estimates. Unlike traditional MHTalgorithms, the Set MHT does not “forget” uncertainty in targetidentities, i.e. display an unjustifiably high confidence level inthe target identities, as a result of pruning out competinghypotheses. Rather, it uses merging techniques while avoiding theshortcomings of traditional Gaussian mixture reduction trackers.
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| 18. |
- Dahlöf, Björn, 1953, et al.
(author)
-
Addition of the calcium antagonist PN 200-110 to pindolol markedly augments the antihypertensive effect in essential hypertension.
- 1987
-
In: Journal of cardiovascular pharmacology. - 0160-2446. ; 10 Suppl 10
-
Journal article (peer-reviewed)abstract
- Several large-scale studies have recently drawn attention to the fact that arterial hypertension frequently is inadequately controlled and that therapeutic alternatives other than the commonly employed stepped-care treatment may be needed in order to obtain normotension. For this reason PN 200-110, a new dihydropyridine calcium antagonist--at two different dose levels (average 3.8 mg b.i.d. or 5.7 mg b.i.d.)--or placebo was added in a double-blind cross-over trial to pindolol, 10 mg per day, in 20 patients with essential hypertension, after an initial 3-week placebo period. Ionized calcium in serum was determined repeatedly during the study. From an initial level of 157/100 mm Hg, PN 200-110 at the first dose level reduced blood pressure by 14/11 mm Hg (p less than 0.01/0.001) and at the second dose level reduced blood pressure by 22/18 mm Hg (p less than 0.001/0.001). The reduction in mean arterial pressure was significantly correlated to age (=0.050, p less than 0.05). There was no significant increase in heart rate, nor were there any significant correlations between ionized calcium and the effect of PN 200-110 nor between the changes in ionized calcium and the changes in blood pressure. Adverse effects were few and mild. One patient had to be withdrawn because of side effects, probably not related to the investigated drugs. Thus, addition of PN 200-110 to hypertensive patients treated with pindolol caused highly significant and clinically relevant further reductions in arterial pressure. The results show that a combination of this kind offers the possibility of good blood pressure control.
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| 19. |
- Dahlöf, Björn, 1953, et al.
(author)
-
Potentiation of the antihypertensive effect of enalapril by randomized addition of different doses of hydrochlorothiazide.
- 1985
-
In: Journal of hypertension. Supplement : official journal of the International Society of Hypertension. - 0952-1178. ; 3:3
-
Journal article (peer-reviewed)abstract
- The purpose of this study was to evaluate the potentiating effect of hydrochlorothiazide (HCTZ) 12.5 or 25 mg once daily when added in a placebo-controlled double-blind randomized study of patients with essential hypertension, whose diastolic blood pressure (DBP) was not adequately controlled (DBP > 90 mmHg) following 6 weeks of single-blind treatment with the angiotensin converting enzyme (ACE) inhibitor enalapril, 20 mg once daily. Forty-eight patients started the first period with enalapril after 4 weeks on placebo. In 13 patients DBP fell to < or = 90 mmHg after enalapril for 6 weeks. In this group supine mean arterial pressure (MAP) was reduced by 13% (P < 0.01). In the patients whose DBP was > 90 mmHg after 6 weeks on enalapril (n = 32) the average supine MAP fell by 9% (P < 0.001). After 3 weeks there was no further drop in blood pressure (BP). Addition of HCTZ to the 32 patients with DBP > 90 mmHg caused a significant further drop in supine BP by 13/7 mmHg with 12.5 mg and by 15/7 mmHg with 25 mg. Seven patients discontinued the study, none due to side effects on enalapril alone. Well-being, assessed with a special questionnaire, was significantly better with enalapril as monotherapy compared with previous treatment, but not different from well-being during the placebo periods. It is concluded that 20 mg enalapril once daily lowered BP effectively and was well tolerated. The maximum BP lowering effect was seen within 3 weeks. Addition of HCTZ caused a significant, and clinically relevant, further drop in BP.(ABSTRACT TRUNCATED AT 250 WORDS)
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| 20. |
- Dahlöf, Björn, 1953, et al.
(author)
-
The long-term effect of isradipine in pindolol-treated patients.
- 1987
-
In: Journal of hypertension. Supplement : official journal of the International Society of Hypertension. - 0952-1178. ; 5:5
-
Journal article (peer-reviewed)abstract
- The long-term efficacy of isradipine, a new dihydropyridine calcium antagonist with marked vascular selectivity, was evaluated in 17 patients with essential hypertension. All had a supine diastolic blood pressure of greater than 95 mmHg with 10 mg pindolol once daily. After a short-term, double-blind, dose-finding, crossover comparison with addition of isradipine or placebo twice daily, they continued on pindolol and their optimal dose of isradipine in a single-blind, long-term follow-up study. Eighteen patients were recruited but one male patient discontinued treatment after 2 weeks due to ankle oedema and will not be accounted for in the overall evaluation. There were 11 males and six females with a mean age of 56 +/- 10 years. In the short-term study on the optimal dose of isradipine (5.1 mg twice daily) blood pressure was lowered by 24/18 mmHg (P less than 0.001). No change in heart rate was seen despite the substantial drop in blood pressure. In the long-term study the patients were seen for a mean follow-up time of 12.5 months (range 4-17 months). After the longest follow-up time mean arterial pressure was 107.0 +/- 7.4 compared with 120.1 +/- 8.2 mmHg after placebo baseline [delta = 13 mmHg (11%), P less than 0.001, n = 17]. The heart rate was unchanged (delta = 0.2 beats/min, 95% confidence limits -3, +3), and so was ankle circumference (delta = 0.12 cm, 95% confidence interval, -1, +1). On the other hand, mean weight was reduced by 2 kg from 90 kg (P less than 0.05, n = 17).(ABSTRACT TRUNCATED AT 250 WORDS)
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| 21. |
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| 22. |
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| 23. |
- Funck, Elin, et al.
(author)
-
Det medicinska professionella fältet
- 2019. - 1
-
In: Ett professionellt landskap i förvandling. - Lund : Studentlitteratur AB. - 9789144122274 ; , s. 271-306
-
Book chapter (peer-reviewed)
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| 24. |
|
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| 25. |
- Guerriero, Marco, et al.
(author)
-
Shooting two birds with two bullets: how to find Minimum Mean OSPA estimates
- 2010
-
In: Proceedings of the 13th International Conference on Information Fusion.
-
Conference paper (peer-reviewed)abstract
- Most area-defense formulations followfrom the assumption that threats must first be identifiedand then neutralized. This is reasonable, but inherentto it is a process of labeling: threat A must be identifiedand then threat B, and then action must be taken.This manuscript begins from the assumption that suchlabeling (A & B) is irrelevant. The problem naturallydevolves to one of Random Finite Set (RFS) estimation:we show that by eschewing any concern of targetlabel we relax the estimation procedure, and it is perhapsnot surprising that by such a removal of constraint (oflabeling) performance (in terms of localization) is enhanced.A suitable measure for the estimation of unlabeledobjects is the Mean OSPA (MOSPA). We derive ageneral algorithm which provided the optimal estimatorwhich minimize the MOSPA. We call such an estimatora Minimum MOSPA (MMOSPA) estimator.
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| 26. |
- Gunaydin, Gokce, et al.
(author)
-
Mutations in Toll-Like Receptor 3 Are Associated with Elevated Levels of Rotavirus-Specific IgG Antibodies in IgA-Deficient but Not IgA-Sufficient Individuals
- 2014
-
In: Clinical and Vaccine Immunology. - : American Society for Microbiology. - 1556-6811 .- 1556-679X. ; 21:3, s. 298-301
-
Journal article (peer-reviewed)abstract
- Double-stranded RNA (dsRNA) triggers immune-mediated responses through toll-like receptor 3 (TLR3), which is involved in innate antiviral defense. Low expression of TLR3 was recently suggested to contribute to susceptibility to rotavirus infection. Thus, we investigated the role of two TLR3 polymorphisms (rs3775291 and rs5743305), both of which resulted in reduced protein function or expression, in healthy blood donors and IgA-deficient (IgAD) individuals. These polymorphisms were associated with elevated rotavirus-specific IgG titers in IgAD individuals but not in healthy individuals. Thus, we propose that TLR3 signaling does not contribute to the rotavirus-specific antibody response in IgA-sufficient individuals, whereas it is associated with elevated antibody titers in IgAD individuals.
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| 27. |
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| 28. |
- Hess, Georg, 1996, et al.
(author)
-
Masked Autoencoder for Self-Supervised Pre-Training on Lidar Point Clouds
- 2023
-
In: Proceedings - 2023 IEEE/CVF Winter Conference on Applications of Computer Vision Workshops, WACVW 2023. ; , s. 350-359
-
Conference paper (peer-reviewed)abstract
- Masked autoencoding has become a successful pretraining paradigm for Transformer models for text, images, and, recently, point clouds. Raw automotive datasets are suitable candidates for self-supervised pre-training as they generally are cheap to collect compared to annotations for tasks like 3D object detection (OD). However, the development of masked autoencoders for point clouds has focused solely on synthetic and indoor data. Consequently, existing methods have tailored their representations and models toward small and dense point clouds with homogeneous point densities. In this work, we study masked autoencoding for point clouds in an automotive setting, which are sparse and for which the point density can vary drastically among objects in the same scene. To this end, we propose Voxel-MAE, a simple masked autoencoding pre-training scheme designed for voxel representations. We pre-train the backbone of a Transformer-based 3D object detector to reconstruct masked voxels and to distinguish between empty and non-empty voxels. Our method improves the 3D OD performance by 1.75 mAP points and 1.05 NDS on the challenging nuScenes dataset. Further, we show that by pre-training with Voxel-MAE, we require only 40 of the annotated data to outperform a randomly initialized equivalent. Code is available at https://github.com/georghess/voxel-mae.
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| 29. |
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| 30. |
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| 31. |
- Istrate, Claudia, et al.
(author)
-
Individuals with selective IgA deficiency resolve rotavirus disease and develop higher antibody titers ( IgG, IgG1) than IgA competent individuals
- 2008
-
In: Journal of Medical Virology. - : Wiley. - 0146-6615 .- 1096-9071. ; 80:3, s. 531-535
-
Journal article (peer-reviewed)abstract
- While IgA is proposed to be essential to control rotavirus disease, no information is available how IgA deficient individuals modulate rotavirus disease and immune responses. We report that individuals (n=62) with selective IgA deficiency ( IgA-D) (<0,05g/l) resolve rotavirus disease and show higher total IgG and IgG1 subclass antibody titers to rotavirus than IgA proficient individuals ( n=62) (GMT 18101 vs 4000 (p<0.005); 8463 vs 1691, (p<0.005). We conclude that IgA is not essential for resolving rotavirus infection in humans.
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| 32. |
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| 33. |
- Krishnan, Rajet, 1982, et al.
(author)
-
Variational Bayesian Framework for Receiver Design in the Presence of Phase Noise in MIMO Systems
- 2012
-
In: IEEE Wireless Communications and Networking Conference, WCNC. - 1525-3511. - 9781467304375 ; , s. 347-352
-
Conference paper (peer-reviewed)abstract
- In this work, the problem of receiver design for phasenoise estimation and data detection in the presence of oscillator phase noise in a point-to-point multiple-input multiple-output (MIMO) system is addressed. First, we discuss some interesting and challenging aspects in receiver design for MIMO systems in thepresence of Wiener phase noise. Then, using the variational Bayesian (VB) framework, a joint iterative phase noise estimator and symbol detector are developed based on inverse Gibbs or variational free energy maximization. Further, the symbol error probability (SEP) of the newly proposed iterative scheme is compared with the optimal ML detector with perfect phase information for 16-PSK and 16-QAM modulation schemes.
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| 34. |
- Kängsepp, Pille, et al.
(author)
-
Column studies aiming at identification of suitable filter materials for pollutant removal from landfill leachate
- 2008
-
In: International Journal of Environment and Waste Management. - 1478-9876 .- 1478-9868. ; 2:6, s. 506-525
-
Journal article (peer-reviewed)abstract
- Landfill leachate contains a complex mixture of inorganic and organic pollutants, which need to be removed before they pollute the environment. Different filter media (peat mixed with either carbon-containing ash, polyurethane waste, or wood pellets) were investigated with respect to their possibility to simultaneously and at low initial concentrations remove metals, polar and non-polar organic compounds. The mixture of peat and carbon-containing ash was found to be the best medium. Reduction in leachate of phenolic substances was 96%, of PBDEs was over 98%, of DOC 40% and of important metals as Cu, Pb and Sn 60%, 90% and 93%, respectively.
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| 35. |
- Kängsepp, Pille, et al.
(author)
-
Column studies aiming at identification of suitable filter materials for pollutant removal from landfill leachate
- 2008
-
In: International Journal of Environment and Waste Management. - : Inderscience Enterprises Ltd.. - 1478-9876 .- 1478-9868. ; 2:6, s. 506-525
-
Journal article (peer-reviewed)abstract
- Landfill leachate contains a complex mixture of inorganic and organic pollutants, which need to be removed before they pollute the environment. Different filter media (peat mixed with either carbon-containing ash, polyurethane waste, or wood pellets) were investigated with respect to their possibility to simultaneously and at low initial concentrations remove metals, polar and non-polar organic compounds. The mixture of peat and carbon-containing ash was found to be the best medium. Reduction in leachate of phenolic substances was 96%, of PBDEs was over 98%, of DOC 40% and of important metals as Cu, Pb and Sn 60%, 90% and 93%, respectively.
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| 36. |
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| 37. |
- Marcotte, Harold, et al.
(author)
-
Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents Infection of Omicron lineages
- 2024
-
In: Proceedings of the National Academy of Sciences of the United States of America. - : NATL ACAD SCIENCES. - 0027-8424 .- 1091-6490. ; 121:3
-
Journal article (peer-reviewed)abstract
- The emergence of Omicron lineages and descendent subvariants continues to present a severe threat to the effectiveness of vaccines and therapeutic antibodies. We have previ- ously suggested that an insufficient mucosal immunoglobulin A (IgA) response induced by the mRNA vaccines is associated with a surge in breakthrough infections. Here, we further show that the intramuscular mRNA and/or inactivated vaccines cannot suffi- ciently boost the mucosal secretory IgA response in uninfected individuals, particu- larly against the Omicron variant. We thus engineered and characterized recombinant monomeric, dimeric, and secretory IgAl antibodies derived from four neutralizing IgG monoclonal antibodies (mAbs 01A05, rmAb23, DXP-604, and XG014) targeting the receptor-binding domain of the spike protein. Compared to their parental IgG antibod- ies, dimeric and secretory IgAl antibodies showed a higher neutralizing activity against different variants of concern (VOCs), in part due to an increased avidity. Importantly, the dimeric or secretory IgAl form of the DXP-604 antibody significantly outperformed its parental IgG antibody, and neutralized the Omicron lineages BA.1, BA.2, and BA.4/5 with a 25- to 75-fold increase in potency. In human angiotensin converting enzyme 2 (ACE2) transgenic mice, a single intranasal dose of the dimeric IgA DXP-604 conferred prophylactic and therapeutic protection against Omicron BA.5. Thus, dimeric or secre- tory IgA delivered by nasal administration may potentially be exploited for the treatment Iand prevention of Omicron infection, thereby providing an alternative tool for combating immune evasion by the current circulating subvariants and, potentially, future VOCs.
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| 38. |
- Martensson, Lennart, et al.
(author)
-
Development and application of an analytical protocol for evaluation of treatment processes for landfill leachates. II. Evaluation of leachate treatment efficiency of different steps in a constructed pilot plant
- 2007
-
In: International Journal of Environmental Analytical Chemistry. - : Informa UK Limited. - 1029-0397 .- 0306-7319. ; 87:1, s. 17-27
-
Journal article (peer-reviewed)abstract
- Different methods for treatment of leachate from a municipal solid waste (MSW) landfill were tested in a pilot plant. Raw leachate was pre-treated with aeration and sedimentation, followed by several parallel individual steps such as bioremediation, chemical oxidation, ozonation, and geo-bed filters. The efficiency of different treatment steps was evaluated according to one previously developed protocol, which includes measurements of several parameters such as conductivity, pH, nutrients, chloride, metals, organic compounds, and acute toxicity before and after a treatment step. The treatment steps which showed the highest efficiency towards organic pollutants in leachate were ozone treatment and chemical oxidation. The use of an adsorption filter, a geo-bed with a mixture of peat and bottom ash with ca 10% remaining carbon, also had good effects. A combination of pre-treatment and a geo-bed filter with peat and carbon ash gave the best overall treatment results when water-quality parameters such as total organic carbon and ammonia-nitrogen were also considered.
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| 39. |
- Mårtensson, Lennart, 1957-, et al.
(author)
-
Development and application of an analytical protocol for evaluation of treatment processes for landfill leachates : II. Evaluation of leachate treatment efficiency of different steps in a constructed pilot plant
- 2007
-
In: International Journal of Environmental Analytical Chemistry. - 0306-7319 .- 1029-0397. - 0306-7319 ; 87:1, s. 17-27
-
Journal article (peer-reviewed)abstract
- Different methods for treatment of leachate from a municipal solid waste (MSW) landfill were tested in a pilot plant. Raw leachate was pre-treated with aeration and sedimentation, followed by several parallel individual steps such as bioremediation, chemical oxidation, ozonation, and geo-bed filters. The efficiency of different treatment steps was evaluated according to one previously developed protocol, which includes measurements of several parameters such as conductivity, pH, nutrients, chloride, metals, organic compounds, and acute toxicity before and after a treatment step. The treatment steps which showed the highest efficiency towards organic pollutants in leachate were ozone treatment and chemical oxidation. The use of an adsorption filter, a geo-bed with a mixture of peat and bottom ash with ca 10% remaining carbon, also had good effects. A combination of pre-treatment and a geo-bed filter with peat and carbon ash gave the best overall treatment results when water-quality parameters such as total organic carbon and ammonia-nitrogen were also considered.
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| 40. |
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| 41. |
- Nilsson-Lindström, Margareta, et al.
(author)
-
Utbildningsfältets omvandling och läraryrkenas professionalisering
- 2019
-
In: Ett professionellt landskap i förvandling. - 9789144122274 ; , s. 127-169
-
Book chapter (other academic/artistic)abstract
- Kapitlet behandlar läraryrkenas positioner och professionsstatus på utbildningens fält. Efter ett kort inledande avsnitt om fältet följer en översikt över svensk skolpolitik de senaste decennierna. Översikten fokuserar skolan och läraryrkenas samhälleliga inbäddning och förutsättningar efter skolverksamhetens kommunalisering och avreglering. Skolan som arbetsorganisation, rektorers framskjutna position som arbetsgivarrepresentanter och den ur professionaliseringssynpunkt strategiska betydelsen av lärarlegitimation och karriärtjänster diskuteras med utgångspunkt från Eliot Freidsons tre konkurrerande styrningslogiker – professionalismens, byråkratins och marknadens. Slutsatsen är att mixen av olika styrningslogiker förändrats på professionens bekostnad till förmån för byråkratins och marknadens. Kan lärarlegitimation och karriärtjänster fungera som lärarförbundens språngbräda i en för läraryrkenas professionalisering problematisk utbildningspolitisk kontext?
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| 42. |
- Nilsson-Lindström, Margareta, et al.
(author)
-
Utbildningsfältets professionalisering
- 2019
-
In: Det professionella landskapets framväxt. - 9789144122052 ; , s. 147-208
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Book chapter (other academic/artistic)abstract
- Kapitlet behandlar det svenska utbildningsfältets professionalisering från kyrkligt förankrade kunskapsideal till skolundervisningens förvetenskapligande. Utbildningsfältet är avgränsat i förhållande till den högre utbildningens fält och omfattar utbildningar på grundskole- och gymnasienivå. I Bourdieus mening är fältet ett system av specialiserade institutioner och agenter (kyrka, stat, akademi, lärarförbund etc.) som utifrån olika intressen och positioner konkurrerar om erkännande och makt att definiera skolutbildningens syften och innehåll. Fältets framväxt och förändring följer olika faser från formering, konsolidering och konstituering till professionalisering. Den historiska exposén visar hur kampen mellan etablerade och konkurrerande kunskapsideal och utbildningspolitiska intressen utmynnade i att existerande strukturer utmanades och förändrades. Nya skolformer och lärarkategorier växte fram och etablerades. Den senaste fasen, fältets professionalisering, inleddes med välfärdsstatens strävan att modernisera och demokratisera skolundervisningen genom inrättandet av ett enhetligt skolsystem, en ny lärarprofession samt förvetenskapligande av lärarutbildningen och läraryrkets kunskapsbas.
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| 43. |
- Nordgren, Johan, et al.
(author)
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Both lewis and secretor status mediate susceptibility to rotavirus infections in a rotavirus genotype-dependent manner.
- 2014
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In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. - : Oxford University Press (OUP). - 1537-6591 .- 1058-4838. ; 59:11, s. 1567-73
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Journal article (peer-reviewed)abstract
- The live oral rotavirus (RV) vaccines have shown a reduced efficacy in Africa. Recent in vitro studies have shown binding of the RV surface protein (VP4) to histo-blood group antigens (HBGAs) in an RV genotype-dependent manner, suggesting them to be putative receptors for RV. The diversity of HBGA phenotypes in different ethnic populations, combined with prevalence/absence of specific RV genotypes, led us to hypothesize whether the genetic variations in HBGAs in a population limit susceptibility to certain RV genotypes, plausibly leading to reduced vaccine efficacy.
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| 44. |
- Pant, Neha, et al.
(author)
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Lactobacilli expressing variable domain of llama heavy-chain antibody fragments (lactobodies) confer protection against rotavirus-induced diarrhea
- 2006
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In: Journal of Infectious Diseases. - 0022-1899 .- 1537-6613. ; 194:11, s. 1580-1588
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Journal article (peer-reviewed)abstract
- Background. Rotavirus-induced diarrhea poses a worldwide medical problem in causing substantial morbidity and mortality among children in developing countries. We therefore developed a system for passive immunotherapy in which recombinant lactobacilli constitutively express neutralizing variable domain of llama heavy-chain (VHH) antibody fragments against rotavirus. Methods. VHH were expressed in Lactobacillus paracasei, in both secreted and cell surface-anchored forms. Electron microscopy was used to investigate the binding efficacy of VHH-expressing lactobacilli. To investigate the in vivo function of VHH-expressing lactobacilli, a mouse pup model of rotavirus infection was used. Results. Efficient binding of the VHH antibody fragments to rotavirus was shown by enzyme-linked immunosorbent assay and scanning electron microscopy. VHH fragments expressed by lactobacilli conferred a significant reduction in infection in cell cultures. When administered orally, lactobacilli-producing surface-expressed VHH markedly shortened disease duration, severity, and viral load in a mouse model of rotavirus-induced diarrhea when administered both fresh and in a freeze-dried form. Conclusions. Transformed lactobacilli may form the basis of a novel form of prophylactic treatment against rotavirus infections and other diarrheal diseases. © 2006 by the Infectious Diseases Society of America. All rights reserved.
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| 45. |
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| 46. |
- Rahmathullah, Abu Sajana, 1986, et al.
(author)
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Merging-based forward-backward smoothing on Gaussian mixtures
- 2014
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In: 17th International Conference on Information Fusion, FUSION 2014; Salamanca; Spain; 7 July 2014 through 10 July 2014. - 9788490123553 ; , s. -
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Conference paper (peer-reviewed)abstract
- Conventional forward-backward smoothing (FBS) for Gaussian mixture (GM) problems are based on pruning methods which yield a degenerate hypothesis tree and often lead to underestimated uncertainties. To overcome these shortcomings, we propose an algorithm that is based on merging components in the GM during filtering and smoothing. Compared to FBS based on the N-scan pruning, the proposed algorithm offers better performance in terms of track loss, root mean squared error (RMSE) and normalized estimation error squared (NEES) without increasing the computational complexity.
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| 47. |
- Rahmathullah, Abu Sajana, 1986, et al.
(author)
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Smoothed probabilistic data association filter
- 2013
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In: FUSION 2013, 9-12 July 2013, Istanbul, Turkey. - 9786058631113 ; , s. 1296 - 1303
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Conference paper (peer-reviewed)abstract
- This paper presents the Smoothed Probabilistic Data Association Filter (SmPDAF) that attempts to improve the Gaussian approximations used in the Probabilistic Data Association Filter (PDAF). This is achieved by using information from future measurements. Newer approximations of the densities are obtained by using a combination of expectation propagation, which provides the backward likelihood information from the future measurements, and pruning, which uses these backward likelihoods to reduce the number of components in the Gaussian mixture. Performance comparison between SmPDAF and PDAF shows us that the root mean squared error performance of SmPDAF is significantly better than PDAF under comparable track loss performance.
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| 48. |
- Rahmathullah, Abu Sajana, 1986, et al.
(author)
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Two-filter Gaussian mixture smoothing with posterior pruning
- 2014
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In: 17th International Conference on Information Fusion, FUSION 2014, Salamanca, Spain, 7-10 July 2014. - 9788490123553 ; , s. Art. no. 6916249-
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Conference paper (peer-reviewed)abstract
- In this paper, we address the problem of smoothing on Gaussian mixture (GM) posterior densities using the two-filter smoothing (TFS) strategy. The structure of the likelihoods in the backward filter of the TFS is analysed in detail. These likelihoods look similar to GMs, but are not proper density functions in the state-space since they may have constant value in a subspace of the state space. We present how the traditional GM reduction techniques can be extended to this kind of GMs. We also propose a posterior-based pruning strategy, where the filtering density can be used to make further approximations of the likelihood in thebackward filter. Compared to the forward–backward smoothing(FBS) method based on N-scan pruning approximations, the proposed algorithm is shown to perform better in terms of track loss, normalized estimation error squared (NEES), computational complexity and root mean squared error (RMSE).
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| 49. |
- Saxena, Richa, et al.
(author)
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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
- 2007
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In: Science. - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 316:5829, s. 1331-1336
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Journal article (peer-reviewed)abstract
- New strategies for prevention and treatment of type 2 diabetes (T2D) require improved insight into disease etiology. We analyzed 386,731 common single-nucleotide polymorphisms (SNPs) in 1464 patients with T2D and 1467 matched controls, each characterized for measures of glucose metabolism, lipids, obesity, and blood pressure. With collaborators (FUSION and WTCCC/UKT2D), we identified and confirmed three loci associated with T2D - in a noncoding region near CDKN2A and CDKN2B, in an intron of IGF2BP2, and an intron of CDKAL1 - and replicated associations near HHEX and in SLC30A8 found by a recent whole-genome association study. We identified and confirmed association of a SNP in an intron of glucokinase regulatory protein (GCKR) with serum triglycerides. The discovery of associated variants in unsuspected genes and outside coding regions illustrates the ability of genome-wide association studies to provide potentially important clues to the pathogenesis of common diseases.
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| 50. |
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