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1.
  • Feng, Qingguo, et al. (author)
  • An advanced multi-orbital impurity solver for dynamical mean field theory based on the equation of motion approach
  • 2012
  • In: Journal of Physics. - : IOP Publishing. - 0953-8984 .- 1361-648X. ; 24:5, s. 055603-
  • Journal article (peer-reviewed)abstract
    • We propose an improved fast multi-orbital impurity solver for the dynamical mean field theory based on equations of motion (EOM) for Green's functions and a decoupling scheme. In this scheme the inter-orbital Coulomb interactions are treated fully self-consistently, and involve the inter-orbital fluctuations. As an example of the use of the derived multi-orbital impurity solver, the two-orbital Hubbard model is studied for various cases. Comparisons are made between numerical results obtained with our EOM scheme and those obtained with quantum Monte Carlo and numerical renormalization group methods. The comparison shows a good agreement, but also reveals a dissimilarity of the behaviors of the densities of states which is caused by inter-site inter-orbital hopping effects and on-site inter-orbital fluctuation effects, thus corroborating the assertion of the value of the EOM method for the study of multi-orbital strongly correlated systems.
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  • Lastilla, L., et al. (author)
  • Foss4g date for dsm generation : Sensitivity analysis of the semi-global block matching parameters
  • 2019
  • In: International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences - ISPRS Archives. - : International Society for Photogrammetry and Remote Sensing. ; , s. 67-72
  • Conference paper (peer-reviewed)abstract
    • DATE (Digital Automatic Terrain Extractor) is a Free and Open Source Software for Geospatial (FOSS4G), which combines photogrammetric and computer vision algorithms in order to automatically generate DSMs from multi-view SAR and optical high resolution satellite imagery, following an iterative and pyramidal workflow in order to refine a coarse DSM used as reference. Consequently, DATE is able to face both the issues of DSM generation and epipolar resampling of satellite imagery. The aim of this work is to evaluate DATE performance, by carrying out a sensitivity analysis based on the dense matching parameters. In particular, DATE implements the Semi-Global Block Matching (SGBM) algorithm, a modified version of Semi-Global Matching method: thus, the sensitivity analysis aims at assessing how SGBM parameters – namely, the difference between maximum and minimum disparity (ndisparities), the minimum disparity value (minimumDisp) and the matched block size (SADWindowSize) – affect the efficiency of the disparity map computation and the final DSM accuracy. The analysis focuses on the case study of Trento and of the Adige Valley, which was chosen due to its geomorphological heterogeneity and complexity, allowing to perform an accuracy evaluation on four tiles, characterized by specific roughness frequencies and morphologies (thus having different effects on disparity variations). Several practical indications on the optimal and critical parameter combinations were retrieved; in addition to this, this work highlighted the most influential parameters both in terms of accuracy (minimumDisp) and computation time (ndisparities), paving the way to further principal component analyses. Finally, the obtained results showed no clear relationship between the area morphology and the solution structure. 
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  • Bagnato, A., et al. (author)
  • Workshop on privacy challenges in public and private organizations
  • 2020
  • In: IFIP Advances in Information and Communication Technology. - Cham : Springer. - 9783030425036 ; , s. 82-89
  • Conference paper (peer-reviewed)abstract
    • Recent developments in information technology such as the Internet of Things and the cloud computing paradigm enable public and private organisations to collect large amounts of data to employ various data analytic techniques for extracting important information that helps improve their businesses. Unfortunately, these benefits come with a high cost in terms of privacy exposures given the high sensitivity of the data that are usually processed at powerful third-party servers. Given the ever-increasing of data breaches, the serious damage they cause, and the need for compliance to the European General Data Protection Regulation (GDPR), these organisations look for secure and privacy-preserving data handling practices. During the workshop, we aimed at presenting an approach to the problem of user data protection and control, currently being developed in the scope of the PoSeID-on and PAPAYA H2020 European projects.
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  • Bagnato, Paola, et al. (author)
  • Cooperative but distinct early co-signaling events originate from ERBB2 and ERBB1 receptors upon trastuzumab treatment in breast cancer cells
  • 2017
  • In: Oncotarget. - : IMPACT JOURNALS LLC. - 1949-2553. ; 8:36, s. 60109-60122
  • Journal article (peer-reviewed)abstract
    • ERBB2 receptor belongs to the ERBB tyrosine kinase receptor family. At variance to the other family members, ERBB2 is a constitutively active orphan receptor. Upon ligand binding and activation, ERBB receptors form homo-or hetero-dimers with the other family members, including ERBB2, promoting an intracellular signaling cascade. ERBB2 is the preferred dimerization partner and ERBB2 heterodimers signaling is stronger and longer acting compared to heterodimers between other ERBB members. The specific contribution of ERBB2 in heterodimer signaling is still undefined. Here we report the formation of circular dorsal ruffles (CDRs) upon treatment of the ERBB2-overexpressing breast cancer cell lines SK-BR-3 and ZR751 with Trastuzumab, a therapeutic humanized monoclonal antibody directed against ERBB2. We found that in SK-BR-3 cells Trastuzumab leads to surface redistribution of ERBB2 and ERBB1 in CDRs, and that the ERBB2-dependent ERK1/2 phosphorylation and ERBB1 expression are both required for CDR formation. In particular, in these cells CDR formation requires activation of both the protein regulator of actin polymerization N-WASP, mediated by ERK1/2, and of the actin depolymerizing protein cofilin, mediated by ERBB1. Furthermore, we suggest that this latter event may be inhibited by the negative cell motility regulator p140Cap, as we found that p140Cap overexpression led to cofilin deactivation and inhibition of CDR formation. In conclusion, here we show for the first time an ERBB2-specific signaling contribution to an ERBB2/ERBB1 heterodimer, in the activation of a complex biological process such as the formation of CDRs.
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  • Feng, Pei Zhong, et al. (author)
  • Study on Oxidation Behavior of (W, Mo) Si2 Powders in Air at 400, 500 and 600textordmasculineC
  • 2007
  • In: Progress in powder metallurgy. - Uetikon-Zürich : Trans Tech Publications Inc.. ; , s. 1289-1292
  • Conference paper (peer-reviewed)abstract
    • The oxidation of (W,Mo)Si2 powders has been examined at 400, 500 and 600°C for 12.0 hours in air. It was shown that the low temperature oxidation resistance of (W,Mo)Si2 was worse than that of MoSi 2, and they showed great changes in mass, volume and colour. At 500°C, the amount of volume expansion of (W,Mo)Si2 was as high as about 7-8 times and color changed from black to yellow after 4.0h with MoO 3, WO3, (W,Mo)O3 and amorphous SiO2 as main reaction products. It took about 8.0h to obtain the same results for MoSi2. The mass gain and oxidation rate were relatively slower at 400°C and 600°C than that at 500°C These were probably due to the lower oxidation rate at 400°C and the protective silica glass on surface of powders formed from the volatilization of MoO3, WO3 and (W,Mo)O3 at 600°C, which would restrain the diffusion of molybdenum from matrix to exterior and oxygen from outside to inside and the further accelerated oxidation.
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  • Tomic, S., et al. (author)
  • Influence of conduction-band nonparabolicity on electron confinement and effective mass in GaNxAs1−x∕GaAs quantum wells
  • 2004
  • In: Physical Review B. Condensed Matter and Materials Physics. - 1098-0121 .- 1550-235X. ; 69, s. 245305-
  • Journal article (peer-reviewed)abstract
    • We derive an analytical model to describe the conduction-band states of GaNAs-based quantum well structures, including the band anticrossing effect between N resonant states and the conduction-band edge. The predictions of the model are compared to those obtained using a full ten-band k·p model based on the same set of parameters. Both methods are then tested by comparison with the experimentally determined ground- and excited-state interband transition energies of GaNxAs1−x quantum wells of different well widths and N composition x obtained at 300 K and under hydrostatic pressures up to 2.0 GPa . We show that the transition energies can be described by a consistent set of material parameters in all the samples studied, and present how the conduction to valence-band offset ratio varies strongly with x in GaNxAs1−x∕GaAs quantum well structures. We conclude that the model presented can be used to predict the transition energies and electron subband structure of any GaNxAs1−x∕GaAs quantum well with well width between 2 and 25 nm , and N composition x between 1 and 4% , although further work is still required to confirm the optimum choice for the variation of band offset ratio with composition.
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14.
  • Andriesse, Hanneke, et al. (author)
  • Validity and responsiveness of the Clubfoot Assessment Protocol (CAP). A methodological study
  • 2006
  • In: BMC Musculoskeletal Disorders. - : Springer Science and Business Media LLC. - 1471-2474. ; 7:28
  • Journal article (peer-reviewed)abstract
    • Background: The Clubfoot Assessment Protocol (CAP)is a multi dimensional instrument designed for longitudinal follow up of the clubfoot deformity during growth. Item reliability has shown to be sufficient. In this article the CAP's validity and responsiveness is studied using the Dimeglio classification scoring as a gold standard. Methods: Thirty-two children with 45 congenital clubfeet were assessed prospectively and consecutively at ages of new-born, one, two, four months and two years of age. For convergent/divergent construct validity the Spearman's correlation coefficients were calculated. Discriminate validity was evaluated by studying the scores in bilateral clubfeet. The floor-ceiling effects at baseline (untreated clubfeet) and at two years of age(treated clubfeet) were evaluated. Responsiveness was evaluated by using effect sizes (ES) and by calculating if significant changes (Wilcoxons signed test) had occurred between the different measurement occasions. Results: High to moderate significant correlation were found between CAP mobility I and morphology and the Dimeglio scores (rs = 0.77 and 0.44 respectively). Low correlation was found between CAP muscle function, mobility II and motion quality and the Dimeglio scoring system (rs = 0.20, 0.09 and 0.06 respectively). Of 13 children with bilateral clubfeet, 11 showed different CAP mobility I scores between right and left foot at baseline (untreated) compared with 5 with the Dimeglio score. At the other assessment occasions the CAP mobility I continued to show higher discrimination ability than the Dimeglio. No floor effects and low ceiling effects were found in the untreated clubfeet for both instruments. High ceiling effects were found in the CAP for the treated children and low for the Dimeglio. Responsiveness was good. ES from untreated to treated ranged from 0.80 to 4.35 for the CAP subgroups and was 4.68 for the Dimeglio. The first four treatment months, the CAP mobility I had generally higher ES compared with the Dimeglio. Conclusion: The Clubfoot Assessment Protocol shows in this study good validity and responsiveness. The CAP is more responsive when severity ranges between mild-moderate to severe, while the Dimeglio focuses more on the extremes. The ability to discriminate between different mobility status of the right and left foot in bilaterally affected children in this population was higher compared with the Dimeglio score implicating a better sensitivity for the CAP.
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  • Dittmar, Jakob, 1971-, et al. (author)
  • Pasts renewed in new German graphic storytelling : The past re-told in: Flix: ”Da war mal was”; Nora Krug: ”Belonging”; Mawil: ”Kinderland”; Birgit Weyhe: ”Madgermanes” and ”Im Himmel ist Jahrmarkt”.
  • 2021
  • Conference paper (other academic/artistic)abstract
    • Narrations codify perspectives on the past. Individual narrations and opinions detail stages in that process and are part of the negotiation on the meaning of things. Comics contribute visual negotiations of the past and its artefacts. They primarily document how the past is re-told at that particular moment in time (i.e. their present). They codify generational and cultural perspectives (plural!) on the past in their narratives. They participate in negotiation of the ”floating gap of memory” (Assmann). Narratives about recent history are selectively institutionalised and documented / codified. With growing historic and biographical distance, situations, events, behaviours are re-evalued and re-told. Individual involvement in collective actions becomes re-evalued from focus on a person’s behaviour and responsibility to focusing on the collectives ethical state of mind and actions. BUT: ancestorial involvement can keep excusatory myths intact despite historic evidence against them. With growing biographical / historical distance it becomes easier to be judgemental on individual and collective responsibility: other narratives compete and complement the formation of identity and can limit dependence on particular older narratives if these are not considered crucial by involved individuals. 
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  • Fjällström, Viktor (author)
  • Potential-Induced Degradation and possibilities for recovery of CuIn1-xGaxSe2 thin film solar cells
  • 2015
  • Licentiate thesis (other academic/artistic)abstract
    • The long-term performance of solar modules is of key importance to achieve profitable solar power installations. In this work, the degradation mechanism potential-induced degradation (PID) was investigated for CuIn1-xGaxSe2 (CIGS) thin film solar cells. PID is caused by a combination of certain system voltage situations and environment conditions, such as temperature and humidity. The conditions for PID were reproduced in the lab, using small test cells. A voltage was applied between the solar cell back contact and the rear side of the glass substrate while heating the samples to a temperature of 85°C.Similar to crystalline silicon technology, CIGS solar cells were found to be susceptible to PID. One critical parameter for the degradation behavior is the choice of substrate and its ability to release Na during applied bias. The degradation was found to be linked with Na migration from the substrate into the devices. Solar cells, which were fully deteriorated in terms of electrical performance by PID, were found to have a substantially increased Na concentration. However, solar cells grown on Na free and high resistivity substrates were observed to be PID-resilient.The degradation was shown to partly be non-permanent. Fully degraded CIGS solar cells could recover electrical performance to a certain degree. Three different recovery methods were applied (i) a passive recovery in darkness at room temperature, (ii) accelerated recovery with a reversed bias as compared to the PID treatment and (iii) etching and replacement of the top window layers followed by reversed bias. Recovery to over 90% of the initial efficiency was possible. However, the recovery rate varied depending on the recovery method. The accelerated method was found to reduce the concentration of Na in the buffer layer and interface volumes. The etch recovery method, which consists of renewing window and buffer layers further strengthen the hypothesis that a major part of the degradation could be attributed to the buffer layer and its interface to CIGS.The importance of the buffer layer in PID was further highlighted in the experiment where the standard CdS buffer layer was substituted with Zn(O,S). Both types of solar cells degrade in the PID conditions. Zn(O,S) cells exhibited ohmic current-voltage relationship (no diode characteristics) in the degraded state, while the CdS counterpart had some degree of diode behavior. During recovery with the accelerated method, the CdS cells restored both current-voltage and capacitance-voltage behavior to larger extent than the Zn(O,S) cells. For the latter, the efficiency stayed close to zero throughout the recovery period.
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  • Fjällström, Viktor, et al. (author)
  • Recovery After Potential-Induced Degradation of CuIn1-xGaxSe2 Solar Cells With CdS and Zn(O,S) Buffer Layers
  • 2015
  • In: IEEE Journal of Photovoltaics. - 2156-3381 .- 2156-3403. ; 5:2, s. 664-669
  • Journal article (peer-reviewed)abstract
    • This study deals with potential-induced degradation (PID) of Cu(In,Ga)Se-2-based solar cells and different approaches to subsequent recovery of efficiency. Three different recovery methods were studied: 1) etch recovery, 2) accelerated recovery, and 3) unaccelerated recovery. After being completely degraded, the solar cells with CdS buffer layers recovered their efficiencies at different rates, depending on the method which was used. On the other hand, if Zn(O,S) was used as a buffer layer instead of CdS, the recovery rate was close to zero. The buffer layer type clearly influenced the sodium distribution during PID stressing and recovery, as well as the possibilities for recovery of the electrical performance.
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  • Jing, Jing (author)
  • See and Be Seen : An Inquiry into the Role of Public Space in Combating Loneliness
  • 2023
  • Doctoral thesis (other academic/artistic)abstract
    • Loneliness in cities has been an issue of great concern in public discourse, particularly during and in the aftermath of the COVID-19 pandemic. The detrimental impact of loneliness on health and well-being is well documented and has recently become a rising priority for governments worldwide. Recent literature on the impact of the built environment on loneliness has primarily focused on aspects related to neighborhood and mobility. This thesis makes a novel contribution to the understanding of how to mitigate loneliness in cities by focusing on public space. Urban design and planning play a role in shaping inclusive and accessible public spaces, which promote social interactions in various forms needed to tackle loneliness.This thesis aims to inform how urban design and planning strategies can potentially impact levels of loneliness experienced in cities. It presents five articles that provide new insights, methods and theoretical frameworks for urban design and planning to tackle loneliness. The cover essay synthesizes key learnings, potential applications of findings, and next steps to advance the research agenda to address urban loneliness.Case studies at the neighborhood and city levels were performed to explore both direct and indirect linkages between loneliness and public space. The empirical work carried out in the City of Stockholm, Vienna, and Zurich underscores the spatial dimension of care practice in the everyday life of older adults. Several key common findings have emerged across the case studies. First, public space is an environmental resource that holds the potential to mitigate loneliness in all settings, but its management must be aligned with the local specificness and cultural context. This understanding also suggests that reduced access to desired public spaces may contribute to heightened loneliness. Second, the design, management, and use of public space affect the objective quality of public space and influence its perceived quality. Planning must therefore consider the complexity of how people perceive public space, including their responses to the physical, action, and cognitive facets of place. Third, this study reveals some useful key constructs, such as nature, walking, physical activities, seeing/meeting people, commercial, and ambivalence, which are the underlying components associated with place that can be relevant to the desirability of spending time in a place for those experiencing loneliness.The Stockholm case studies highlight that easily accessible local third places can support feelings of independence and safety, and facilitate social and physical activities for community building (meaningful social connection). As such, these are found to be positive resources for combating loneliness among older adults. Familiarity, and related constructs, such as homeness and neighborhood attachment, are also significant for both young and older adults when they consider places to go during times of feeling lonely. Urban design and planning can help transform neighborhood streetscapes to serve as social infrastructure, delivering higher social and well-being values for all.Collectively, these findings offer nuanced insights to improve the understanding of loneliness from an environmental approach. Urban policymaking, investment, design, planning, and development should consider public space as a promising pathway to combat loneliness. Place-based intervention strategies focused on enabling thriving public spaces will be critical for urban areas to reduce loneliness worldwide.
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  • Jönsson, Per, et al. (author)
  • An Evaluation of k-nearest Neighbour Imputation Using Likert Data
  • 2004
  • Conference paper (peer-reviewed)abstract
    • Studies in many different fields of research suffer from the problem of missing data. With missing data, statistical tests will lose power, results may be biased, or analysis may not be feasible at all. There are several ways to handle the problem, for example through imputation. With imputation, missing values are replaced with estimated values according to an imputation method or model. In the k- Nearest Neighbour (k-NN) method, a case is imputed using values from the k most similar cases. In this paper, we present an evaluation of the k-NN method using Likert data in a software engineering context. We simulate the method with different values of k and for different percentages of missing data. Our findings indicate that it is feasible to use the k-NN method with Likert data. We suggest that a suitable value of k is approximately the square root of the number of complete cases. We also show that by relaxing the method rules with respect to selecting neighbours, the ability of the method remains high for large amounts of missing data without affecting the quality of the imputation.
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  • Kashfi, Pariya, 1980, et al. (author)
  • Integrating UX principles and practices into software development organizations: A case study of influencing events
  • 2019
  • In: Journal of Systems and Software. - : Elsevier BV. - 0164-1212. ; 154, s. 37-58
  • Journal article (peer-reviewed)abstract
    • Current studies on User eXperience (UX) integration often do not investigate or reflect on the transition companies go through from only developing Graphical User Interfaces (GUI) to also considering usability and more recently UX. Understanding this transition provides a more holistic and realistic picture of integration and can be a rich source of knowledge for improving UX integration in the software industry. Applying case study and grounded theory research we show that UX integration, like other organizational changes, can include a mixture of planned and emergent initiatives, and is influenced by various intertwined events; not only those that reside inside an organization but also those external to it. We also show that different decisions that are made outside the authority of UX practitioners have an inevitable impact on enabling or prohibiting UX integration. In addition, we found that for a successful integration, practitioners need to explicitly consider and address the characteristics of UX, otherwise, the integration efforts may have a lopsided focus on the pragmatic aspect of UX, consequently, leave the hedonic aspect unaddressed. Based on our findings, we present four lessons learned and five pitfalls companies should consider to go beyond GUI design and usability to also address UX. (C) 2019 Published by Elsevier Inc.
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  • Paasch, Jesper M., Tekn. dr, Docent, 1962- (author)
  • Metadata in e-government : a study on Metadata for geographic information
  • 2020
  • In: SIIT 2020. - : European Academy for Standardisation.
  • Conference paper (peer-reviewed)abstract
    • Terminology is important in order to achieve an effective e-government. This paper describes an initiative by the Swedish Institute for Standards, SIS, aiming to achieve a homogeneous national terminology for metadata in the Swedish Spatial Data Infrastructure, SDI. The initiative consists of two parts; First, establishing a translation of the English language metadata elements in the international and Swedish standard for metadata for geographic information. Second, to create a national application, i.e. profile, of the standard which even is in accordance with the requirements of metadata for geographic data listed in the European Union´s INSPIRE directive and additional national needs. The translation of metadata terms from English to Swedish together with the publication of a national metadata guideline for the Swedish SDI is an example showing the importance of a national domain specific terminology, such a for metadata describing geographic information to be used in a spatial data infrastructure as part of the development of e-government and electronic information interchange
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  • Prencipe, Maria, et al. (author)
  • Role of serum response factor expression in prostate cancer biochemical recurrence
  • 2018
  • In: The Prostate. - : Wiley. - 0270-4137. ; 78:10, s. 724-730
  • Journal article (peer-reviewed)abstract
    • BACKGROUND: Up to a third of prostate cancer patients fail curative treatment strategies such as surgery and radiation therapy in the form of biochemical recurrence (BCR) which can be predictive of poor outcome. Recent clinical trials have shown that men experiencing BCR might benefit from earlier intervention post-radical prostatectomy (RP). Therefore, there is an urgent need to identify earlier prognostic biomarkers which will guide clinicians in making accurate diagnosis and timely decisions on the next appropriate treatment. The objective of this study was to evaluate Serum Response Factor (SRF) protein expression following RP and to investigate its association with BCR.MATERIALS AND METHODS: SRF nuclear expression was evaluated by immunohistochemistry (IHC) in TMAs across three international radical prostatectomy cohorts for a total of 615 patients. Log-rank test and Kaplan-Meier analyses were used for BCR comparisons. Stepwise backwards elimination proportional hazard regression analysis was used to explore the significance of SRF in predicting BCR in the context of other clinical pathological variables. Area under the curve (AUC) values were generated by simulating repeated random sub-samples.RESULTS: Analysis of the immunohistochemical staining of benign versus cancer cores showed higher expression of nuclear SRF protein expression in cancer cores compared with benign for all the three TMAs analysed (P < 0.001, n = 615). Kaplan-Meier curves of the three TMAs combined showed that patients with higher SRF nuclear expression had a shorter time to BCR compared with patients with lower SRF expression (P < 0.001, n = 215). Together with pathological T stage T3, SRF was identified as a predictor of BCR using stepwise backwards elimination proportional hazard regression analysis (P = 0.0521). Moreover ROC curves and AUC values showed that SRF was better than T stage in predicting BCR at year 3 and 5 following radical prostatectomy, the combination of SRF and T stage had a higher AUC value than the two taken separately.CONCLUSIONS: SRF assessment by IHC following RP could be useful in guiding clinicians to better identify patients for appropriate follow-up and timely treatment.
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  • Singh, S., et al. (author)
  • Multi-objective optimization of machining parameter in laser drilling of glass microballoon/epoxy syntactic foams
  • 2023
  • In: Journal of Materials Research and Technology. - : Elsevier Editora Ltda. - 2238-7854. ; 23, s. 3869-3879
  • Journal article (peer-reviewed)abstract
    • The effect of CO2 laser drilling on glass microballoon/epoxy syntactic foams are investigated in this study to optimize machining parameters to achieve a clean hole for various industrial applications. The epoxy matrix is reinforced with glass microballoons in concentrations of 0, 20 and 40 vol%. Cutting speed, laser power and additive percentage are input parameters for optimization. Kerf taper angle, surface roughness and ovality percentage are used as output responses to evaluate hole quality. For the optimization study, hybrid multi-criteria decision-making methods such as grey relational analysis and multi-objective optimization with ratio assessment methods are used, with equal weightage given to each output response. According to the study, low power and high speed produce better machining results such as a smaller kerf taper angle, lower surface roughness and a lower ovality percentage. Furthermore, a higher additive percentage is not appropriate for laser in epoxy/glass microballoon composite because it burns the area near the laser and increases surface roughness. © 2023 The Author(s)
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  • Skovsted, Christian B., et al. (author)
  • First occurrence of a new Ocruranus-like helcionelloid mollusc from the lower Cambrian of East Gondwana
  • 2012
  • In: Gondwana Research. - : Elsevier BV. - 1342-937X .- 1878-0571. ; 22:1, s. 256-261
  • Journal article (peer-reviewed)abstract
    • A new cap-shaped mollusc, Emargimantus angulatus gen. et sp. nov. is described from the Arrowie Basin of South Australia. The new species is closely comparable to mollusc species from South China and North-East Greenland previously described under the generic name Ocruranus Liu, a genus recently reinterpreted as a multiplated, possibly polyplacophoran mollusc. Emargimantus is interpreted as a univalved helcionelloid mollusc and differs from Ocruranus in both morphology and function. E. angulatus represents the first discovery of Ocruranus-like helcionelloids in the lower Cambrian of eastern Gondwana and demonstrates that these molluscs had a global distribution during the early Cambrian.
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  • Sparrman, Anna, et al. (author)
  • The Ontologies of Child Culture
  • 2013
  • In: TORINO, 28-31 August 2013ESA 11th Conference, Crisis, Critique and Change: Abstract book. - Torino : European Sociological Association (ESA) University of Torino Department of Culture, Politics and Society. - 9788897523499 ; , s. 191-
  • Conference paper (peer-reviewed)
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  • Sparrman, Anna, 1965- (author)
  • The social aesthetics of family space : The visual heritage of Disney in a Swedish amusement park
  • 2022. - 1
  • In: On Disney. - Frankfurt am Main : J.B. Metzler. - 9783662646243 ; , s. 229-247
  • Book chapter (peer-reviewed)abstract
    • Disneyland’s 1955 Main Street is inspired by Walt Disney’s childhood on hometown street. Today, Disney Main Street has become a visual, cultural and historical heritage, and its aesthetic is visible in the architecture of American outlet villages, shopping malls and leisure parks all over the world. The Swedish amusement park Liseberg is one example of a place that reflects its influence. Initially this project set out to use visual documentation to explore the transference of Disney Main Street to a local context. In the course of this endeavour, however, its aim became to take on board an approach that can twist and challenge the settled, consensus view that Disney Main Street is an infantilising construct. So, the chapter begins by facing its own challenge: how to say something new about the well-trodden ground of Disney Main Street. This is resolved via the premise that methods enact the topics we research. The chapter will thus demonstrate that it is possible to avoid taking on the assumptions of earlier research in discussing Disney Main Street. This is achieved by discussing Main Street with family ethnography and the concepts of pure and impure critique (Illouz 2007). What emerges is a more ambiguous and complex interpretation of both Main Streets and their visitors.
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  • Szczuraszek, Tomasz, et al. (author)
  • A complementary information traffic safety system
  • 1996
  • In: Proceedings of Road safety in Europe. Conference in Birmingham, United Kingdom, September 9-11, 1996. - Linköping : Statens väg- och transportforskningsinstitut. ; , s. 259-275
  • Conference paper (other academic/artistic)
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  • Wang, Yiqiao (author)
  • Molecular regulation of somatosensory neuron development
  • 2019
  • Doctoral thesis (other academic/artistic)abstract
    • The somatosensory system of vertebrates perceives and transmits a variety of information from both external and internal environments to the central nervous system where an integrated response is established leading to adaptive outcome. Specific classes of sensory neurons convey the information consisting of touch, muscle stretch, temperature, itch, and pain. Each type of sensory neuron expresses a group of specific markers or proteins in order to perform a specialized function. However, the mechanisms that ensure the acquisition of various molecular traits by somatosensory neurons during development is still not fully understood. This doctoral thesis explores several early developmental events for different types of somatosensory neurons at molecular and cellular levels in order to reduce the gap of knowledge in this field. In Paper I and II, we investigated the neuronal specification of nociceptive neurons, which were derived from specific waves of neurogenesis. We found that PRDM12, an epigenetic regulator, was necessary for the entire nociceptive lineage to develop. In the absence of PRDM12, neural crest precursors failed to generate all of the nociceptive neurons. We also found that the key transcription factor RUNX1, which plays an important role in the diversification of nociceptive neurons, was induced by factors released by early born neurons, emphasizing the important influence of the environment created by early postmitotic neurons on the fate of later born neurons. In Paper III, we proposed a new cell selection model in the early cell death of sensory neurons using the proprioceptive neurons population as a model system. The canonical neurotrophic theory suggests similarity of neurons when competing for target-derived neurotrophins for their survival. However, our data showed that early proprioceptive neurons exhibit a molecular heterogeneity code leading to different capacities to survive already before the cell death period. Further, this capacity was intrinsically regulated by the transcription factor RUNX3 whose expression was defined by the surrounding morphogen retinoic acid. Finally, in Paper IV, we showed that the transcription factor RUNX3 controls the axonal growth rate of developing sensory neurons in a strict temporal and spatial manner. Taking advantage of both chicken embryos and mouse genetics, we observed that the difference in peripheral nerve growth at different axial levels was encoded by RUNX3 expression. In summary, the data collected in this thesis describes several new insights into the molecular regulation during the step-wise development of somatosensory neurons, including neurogenesis, neuronal specification, early cell death, and axonal growth. This knowledge will help us to the better understanding of the development of the somatosensory system as well as provide new knowledge that might help improving approaches of treatment for patients with somatosensory disorders such as congenital insensitivity to pain.
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39.
  • Wang, Z H, et al. (author)
  • Ketoacidosis occurs in both Type 1 and Type 2 diabetes : a population-based study from Northern Sweden
  • 2008
  • In: Diabetic Medicine. - : Wiley. - 0742-3071 .- 1464-5491. ; 25:7, s. 867-870
  • Journal article (peer-reviewed)abstract
    • AIMS:To determine the occurrence of diabetic ketoacidosis (DKA) in adult Type 2 and Type 1 diabetic patients in Northern Sweden and to determine whether DKA presents with a different clinical picture in Type 2 compared with Type 1 diabetic subjects.METHODS:All adult patients from a hospital catchment area in Northern Sweden with diagnosed DKA episodes during 1997-2000 were included in a retrospective study. Medical records and laboratory reports were analysed.RESULTS:During the years 1997 to 2000, the average annual incidence rate for DKA was 5.9 per 100 000 adult inhabitants. Twenty-five patients developed DKA, eight (32%) had Type 2 diabetes, while 17 (68%) had Type 1 diabetes. Type 2 diabetic patients with DKA were older and had higher levels of C-peptide than Type 1 diabetic patients. On admission because of DKA, a similar degree of hyperglycaemia was present in Type 1 and Type 2 patients. Metabolic acidosis was more severe in Type 1 compared with Type 2 diabetic patients. In 50% of the Type 2 diabetic patients, diabetes was diagnosed at the episode of DKA.CONCLUSIONS:DKA occurs in Caucasian Type 2 diabetic patients within a Swedish population. Although the frequency of DKA is much higher in Type 1 diabetic patients, Type 2 diabetes may account for as much as one-third of the overall DKA cases.
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40.
  • Zimmerman, Jenny K M, 1972- (author)
  • Superbyråkratens metod för examination av skriftliga inlämningsuppgifter – En hjälp för studenter att utveckla sitt skrivande?
  • 2023
  • Conference paper (peer-reviewed)abstract
    • Många skriftliga inlämningsuppgifter innehåller otillräcklig information ellerspråkfel. När informationen i uppgiften är otillräcklig underkänns den medstöd av kursens lärandemål. Det händer att uppgifter med grava språkfel godkänns när det saknas stöd i kursens lärandemål för att bedöma skrivförmåga.Det är en lösning som både är rättsosäker och gör studenten en björntjänst.Studenten lär sig att den inte behöver kommunicera skriftlig information påett begripligt sätt och riskerar att få problem i yrkeslivet. Det behövs kunskap om hur man kan genomföra en rättssäker examination av studentersförmågor och ge studenter förutsättningar att kommunicera på ett begripligt sätt i yrkeslivet. Jag har utvecklat en metod för examination av skriftligainlämningsuppgifter som möter dessa behov. Den utgår från Förvaltningslagens krav på klarhet och fullständighet i kombination med läroplanerna förgymnasieskolans kurser i svenska. Efter att ha använt metoden under fleraår i ingenjörs- och kandidatutbildningar vid Mittuniversitetet är erfarenhetenatt bedömning av studenternas förmågor i förhållande till lärandemålen blirenklare och går snabbare. Det gör att studenter får tidigare återkoppling ochbeslut om betyg. Dessutom identifieras studenter med behov av att utvecklaförmågan att skriva texter som följer skriftspråkets normer för språkriktighet,är sammanhängande, begripliga och har en tydligt urskiljbar disposition. Jagvill presentera Superbyråkratens metod och diskutera hur universitetet ochhögskolor kan ge stöd åt de studenter som identifieras med ett utvecklingsbehov av sin skrivförmåga.
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