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  • Ratke, L., et al. (author)
  • Lead-free bearing alloys for engine applications results of the ESA-MAP project MONOPHAS
  • 2007
  • In: Transactions of the Indian Institute of Metals. - 0019-493X. ; 60:2-3, s. 103-111
  • Journal article (peer-reviewed)abstract
    • Recent developments to reduce fuel consumption, emission and air pollution, size and weight of engines for automotive, truck, ship propulsion and electrical power generation lead to temperature and load conditions within engines that cannot be provided by conventional bearings. Therefore a European project has been established to develop a technically usable aluminium based lead free bearing material with sufficient hardness, wear and friction properties and good corrosion resistance to be produced with semi-continuous casting process. The paper describes the scientific challenges, approaches to tackle the solidification and casting problems and presents some illustrative research results.
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3.
  • Weller, Michael, et al. (author)
  • EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood.
  • 2021
  • In: Nature reviews. Clinical oncology. - : Springer Science and Business Media LLC. - 1759-4782 .- 1759-4774. ; 18, s. 170-186
  • Research review (peer-reviewed)abstract
    • In response to major changes in diagnostic algorithms and the publication of mature results from various large clinical trials, the European Association of Neuro-Oncology (EANO) recognized the need to provide updated guidelines for the diagnosis and management of adult patients with diffuse gliomas. Through these evidence-based guidelines, a task force of EANO provides recommendations for the diagnosis, treatment and follow-up of adult patients with diffuse gliomas. The diagnostic component is based on the 2016 update of the WHO Classification of Tumors of the Central Nervous System and the subsequent recommendations of the Consortium to Inform Molecular and Practical Approaches to CNS Tumour Taxonomy - Not Officially WHO (cIMPACT-NOW). With regard to therapy, we formulated recommendations based on the results from the latest practice-changing clinical trials and also provide guidance for neuropathological and neuroradiological assessment. In these guidelines, we define the role of the major treatment modalities of surgery, radiotherapy and systemic pharmacotherapy, covering current advances and cognizant that unnecessary interventions and expenses should be avoided. This document is intended to be a source of reference for professionals involved in the management of adult patients with diffuse gliomas, for patients and caregivers, and for health-care providers.
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