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- Roller, Jonas, et al.
(author)
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How to detect a dwarf - in vivo imaging of nanoparticles in the lung.
- 2011
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In: Nanomedicine: Nanotechnology, Biology and Medicine. - : Elsevier BV. - 1549-9642 .- 1549-9634. ; 7:6, s. 753-762
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Journal article (peer-reviewed)abstract
- Nanotechnology is a rapidly developing field in science and industry. The exposure to nanoparticles (NPs) will steadily grow in the future and, thus, there is an urgent need to study potential impacts of the interaction between NPs and the human body. The respiratory tract is the route of entry for all accidentally inhaled NPs. Moreover, NPs may intentionally be delivered into the lung as contrast agents and drug delivery systems. The present review provides an overview of currently used techniques for the in vivo imaging of NPs in the lung, including X-ray, computed tomography (CT), gamma camera imaging, positron emission tomography (PET), magnetic resonance imaging (MRI), near-infrared imaging and intravital fluorescence microscopy. Studies based on these techniques may contribute to the development of novel NP-based drug delivery systems and contrast agents. In addition, they may provide completely new insights into nanotoxicological processes.
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- Schulte, Stefan, et al.
(author)
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Message from the Chairs IC2E 2023
- 2023
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In: 2023 IEEE International Conference on Cloud Engineering (IC2E). - : Institute of Electrical and Electronics Engineers (IEEE). - 9798350343946 ; , s. 9-10
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Conference paper (other academic/artistic)
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- While, Geoffrey M, et al.
(author)
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Sexual selection drives asymmetric introgression in wall lizards.
- 2015
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In: Ecology Letters. - : Wiley. - 1461-023X. ; 18:12, s. 1366-1375
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Journal article (other academic/artistic)abstract
- Hybridisation is increasingly recognised as an important cause of diversification and adaptation. Here, we show how divergence in male secondary sexual characters between two lineages of the common wall lizard (Podarcis muralis) gives rise to strong asymmetries in male competitive ability and mating success, resulting in asymmetric hybridisation upon secondary contact. Combined with no negative effects of hybridisation on survival or reproductive characters in F1-hybrids, these results suggest that introgression should be asymmetric, resulting in the displacement of sexual characters of the sub-dominant lineage. This prediction was confirmed in two types of secondary contact, across a natural contact zone and in two introduced populations. Our study illustrates how divergence in sexually selected traits via male competition can determine the direction and extent of introgression, contributing to geographic patterns of genetic and phenotypic diversity.
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