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Träfflista för sökning "WFRF:(Vrang Sophie) "

Search: WFRF:(Vrang Sophie)

  • Result 1-3 of 3
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1.
  • Alsterholm, Mikael, 1977, et al. (author)
  • Establishment and utility of SwedAD : a nationwide Swedish registry for patients with atopic dermatitis receiving systemic pharmacotherapy
  • 2023
  • In: Acta Dermato-Venereologica. - : Medical Journals Sweden AB. - 0001-5555 .- 1651-2057. ; 103
  • Journal article (peer-reviewed)abstract
    • SwedAD, a Swedish nationwide registry for patients with atopic dermatitis receiving systemic pharmacotherapy, was launched on 1 September 2019. We describe here the establishment of a user-friendly registry to the benefit of patients with atopic dermatitis. By 5 November 2022, 38 clinics had recorded 931 treatment episodes in 850 patients with an approximate national coverage rate of 40%. Characteristics at enrolment included median Eczema Area and Severity Index (EASI) 10.2 (interquartile range 4.0, 19.4), Patient-Oriented Eczema Measure (POEM) 18.0 (10.0, 24.0), Dermatology Life Quality Index (DLQI) 11.0 (5.0, 19.0) and Peak Itch Numerical Rating Scale-11 (NRS-11) 6.0 (3.0, 8.0). At 3 months, median EASI was 3.2 (1.0, 7.3) and POEM, DLQI, and NRS-11 were improved. Regional coverage varied, reflecting the distribution of dermatologists, the ratio of public to private healthcare, and difficulties in recruiting certain clinics. This study highlights the importance of a nationwide registry when managing systemic pharmacotherapy of atopic dermatitis.
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2.
  • Nilsson, Magnus, et al. (author)
  • Discovery of 4 '-azido-2 '-deoxy-2 '-C-methyl cytidine and prodrugs thereof : A potent inhibitor of Hepatitis C virus replication
  • 2012
  • In: Bioorganic & Medicinal Chemistry Letters. - : Elsevier BV. - 0960-894X .- 1464-3405. ; 22:9, s. 3265-3268
  • Journal article (peer-reviewed)abstract
    • 4'-Azido-2'-deoxy-2'-methylcytidine (14) is a potent nucleoside inhibitor of the HCV NS5B RNA-dependent RNA polymerase, displaying an EC50 value of 1.2 mu M and showing moderate in vivo bioavailability in rat (F = 14%). Here we describe the synthesis and biological evaluation of 4'-azido-2'-deoxy-2'-methylcytidine and prodrug derivatives thereof. (C) 2012 Elsevier Ltd. All rights reserved.
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3.
  • Sigurdardottir, Gunnthorunn, et al. (author)
  • Cross-Cultural Validation of the RECAP of Atopic Eczema Question-naire in a Swedish Population
  • 2024
  • In: Acta Dermato-Venereologica. - : Medical Journals Sweden. - 0001-5555 .- 1651-2057. ; 104
  • Journal article (peer-reviewed)abstract
    • A Swedish translation of the patient-reported outcome measure for assessing long-term control of atopic dermatitis, Recap of atopic eczema (RECAP), has not been validated. Cross-cultural translation and multi-centre validation of the translated RECAP questionnaire were therefore performed. Disease severity was assessed using the validated Investigator Global Assessment Scale for atopic dermatitis (vIGA-ADTM). The Swedish RECAP was completed by 208 individuals aged 16 years or older with a median age of 36 years (interquartile range [IQR] 27-48). The participants considered the questionnaire suitable for assessing eczema control. The median RECAP score (range 0-28) was 12 (IQR 5-19). The mean and median vIGA-ADTM scores (range 0-4) were 2 (standard deviation [SD] 2) and 3 (IQR 2-4), respectively. A correlation between RECAP and the vIGA-ADTM was observed (p < 0.001). There was no significant change in scores for participants who answered the questionnaire twice within 14 days. Over time, improved or worsened eczema, as evaluat-ed by vIGA-ADTM, affected RECAP scores significantly (p < 0.001). The study suggests that RECAP can assess AD control in a Swedish clinical setting and shows -acceptable reliability.
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  • Result 1-3 of 3
Type of publication
journal article (3)
Type of content
peer-reviewed (3)
Author/Editor
Lundqvist, Maria (2)
Sonesson, Andreas (2)
Svensson, Åke (2)
Alsterholm, Mikael, ... (2)
von Kobyletzki, Laur ... (2)
Sandström Falk, Mari ... (2)
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Sigurdardottir, Gunn ... (2)
Vrang, Sophie (2)
Bradley, Maria (2)
Johansson, Emma K. (2)
Sandström Falk, Mari ... (2)
Nilsson, Magnus (1)
Lundeberg, Lena (1)
Vrang, Lotta (1)
Rosenquist, Åsa (1)
Samuelsson, Bertil (1)
Agback, Tatiana (1)
Wahlgren, Carl-Fredr ... (1)
Pinho, Pedro (1)
Svedbom, Axel (1)
Anderson, Chris (1)
Holm Sommar, Lena (1)
Ivert, Lina U. (1)
Josefson, Anna, 1965 ... (1)
Lindberg, Magnus, 19 ... (1)
Nylander, Elisabet (1)
Shayesteh, Alexander (1)
Virtanen, Marie (1)
Andersson, Chris D (1)
Sund, Christian (1)
Belfrage, Anna Karin ... (1)
Kalayanov, Genadiy (1)
Wikström, Kristina (1)
Terelius, Ylva (1)
Winqvist, Anna (1)
Zhou, Xiao- Xiong (1)
Wahling, Horst (1)
Pelcman, Michael (1)
Benckestock, Kurt (1)
Boothee, Mirva (1)
Lindqvist, Anneli (1)
Rydegard, Christina (1)
Jonckers, Tim H. M. (1)
Vandyck, Koen (1)
Raboisson, Pierre (1)
Lin, Tse-I (1)
Lachau-Durand, Sophi ... (1)
de Kock, Herman (1)
Smith, David B. (1)
Martin, Joseph A. (1)
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University
University of Gothenburg (2)
Uppsala University (2)
Örebro University (2)
Umeå University (1)
Linköping University (1)
Lund University (1)
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Karolinska Institutet (1)
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Language
English (3)
Research subject (UKÄ/SCB)
Medical and Health Sciences (2)
Natural sciences (1)

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