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- Batani, D., et al.
(author)
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Effects of laser prepulses on laser-induced proton generation
- 2010
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In: New Journal of Physics. - : IOP Publishing. - 1367-2630. ; 12
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Journal article (peer-reviewed)abstract
- Low-intensity laser prepulses (<10(13) W cm(-2), nanosecond duration) are a major issue in experiments on laser-induced generation of protons, often limiting the performances of proton sources produced by high-intensity lasers (approximate to 10(19) W cm(-2), picosecond or femtosecond duration). Depending on the intensity regime, several effects may be associated with the prepulse, some of which are discussed in this paper: (i) destruction of thin foil targets by the shock generated by the laser prepulse; (ii) creation of preplasma on the target front side affecting laser absorption; (iii) deformation of the target rear side; and (iv) whole displacement of thin foil targets affecting the focusing condition. In particular, we show that under oblique high-intensity irradiation and for low prepulse intensities, the proton beam is directed away from the target normal. Deviation is towards the laser forward direction, with an angle that increases with the level and duration of the ASE pedestal. Also, for a given laser pulse, the beam deviation increases with proton energy. The observations are discussed in terms of target normal sheath acceleration, in combination with a laser-controllable shock wave locally deforming the target surface.
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- Cooil, S. P., et al.
(author)
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Iron-mediated growth of epitaxial graphene on SiC and diamond
- 2012
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In: Carbon. - : Elsevier BV. - 0008-6223. ; 50:14, s. 5099-5105
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Journal article (peer-reviewed)abstract
- Ordered graphene films have been fabricated on Fe-treated SiC and diamond surfaces using the catalytic conversion of sp(3) to sp(2) carbon. In comparison with the bare SiC(0 0 0 1) surface, the graphitization temperature is reduced from over 1000 degrees C to 600 degrees C and for diamond (111), this new approach enables epitaxial graphene to be grown on this surface for the first time. For both substrates, a key development is the in situ monitoring of the entire fabrication process using real-time electron spectroscopy that provides the necessary precision for the production of films of controlled thickness. The quality of the graphene/graphite layers has been verified using angle-resolved photoelectron spectroscopy, scanning tunneling microscopy and low energy electron diffraction. Graphene is only formed on treated regions of the surface and so this offers a method for fabricating and patterning graphene structures on SiC and diamond in the solid-state at industrially realistic temperatures. (c) 2012 Elsevier Ltd. All rights reserved.
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- ELSAYED, A, et al.
(author)
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SEISMIC HAZARD OF EGYPT
- 1994
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In: NATURAL HAZARDS. - : KLUWER ACADEMIC PUBL. - 0921-030X. ; 10:3, s. 247-259
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Journal article (other academic/artistic)abstract
- Earthquake hazard parameters such as maximum expected magnitude, M(max), annual activity rate, lambda, and b value of the Gutenberg-Richter relation have been evaluated for two regions of Egypt. The applied maximum likelihood method permits the combinatio
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- Ferri, J., et al.
(author)
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Enhancement of laser-driven ion acceleration in non-periodic nanostructured targets
- 2020
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In: Journal of Plasma Physics. - : Cambridge University Press (CUP). - 0022-3778 .- 1469-7807. ; 86:1
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Journal article (peer-reviewed)abstract
- Using particle-in-cell simulations, we demonstrate an improvement of the target-normal-sheath acceleration (TNSA) of protons in non-periodically nanostructured targets with micron-scale thickness. Compared to standard flat foils, an increase in the proton cutoff energy by up to a factor of two is observed in foils coated with nanocones or perforated with nanoholes. The latter nano-perforated foils yield the highest enhancement, which we show to be robust over a broad range of foil thicknesses and hole diameters. The improvement of TNSA performance results from more efficient hot-electron generation, caused by a more complex laser-electron interaction geometry and increased effective interaction area and duration. We show that TNSA is optimized for a nanohole distribution of relatively low areal density and that is not required to be periodic, thus relaxing the manufacturing constraints.
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- Koskinen, L. O., et al.
(author)
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Prostacyclin treatment normalises the MCA flow velocity in nimodipine-resistant cerebral vasospasm after aneurysmal subarachnoid haemorrhage : a pilot study
- 2009
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In: Acta Neurochirurgica. - : Springer. - 0001-6268 .- 0942-0940. ; 151:6, s. 595-599
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Journal article (peer-reviewed)abstract
- BACKGROUND: Cerebral vasospasm triggered by subarachnoid haemorrhage is one of the major causes of post-haemorrhage morbidity and mortality. Several treatment modalities have been proposed, and none of them are fully effective.METHODS: In this study we treated five patients with prostacyclin suffering vasospasm after a ruptured aneurysm not responding to high i.v. doses of nimodipine. All patients were severely ill, unconscious and in need of intensive care.FINDINGS: A low dose of prostacyclin i.v. infusion for 72 h reversed the vasospasm as measured by transcranial Doppler technique. The mean MCA blood flow velocity decreased from 199 +/- 31 cm/s to 92 +/- 6 cm/s within 72 h after the start of the prostacyclin infusion.CONCLUSIONS: We suggest that low-dose prostacyclin treatment, an old treatment strategy, can be a treatment option in patients with vasospasm not responding to ordinary measures.
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| 15. |
- Ostadkarampour, M., et al.
(author)
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Higher levels of interleukin IL-17 and antigen-specific IL-17 responses in pulmonary sarcoidosis patients with Lofgren's syndrome
- 2014
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In: Clinical and Experimental Immunology. - : Oxford University Press (OUP). - 0009-9104 .- 1365-2249. ; 178:2, s. 342-352
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Journal article (peer-reviewed)abstract
- Sarcoidosis is a granulomatous disorder of unknown aetiology. The presence of Mycobacterium tuberculosis catalase-peroxidase (mKatG) in sarcoidosis tissue has been reported. T helper type 1 (Th1) responses against mKatG have previously been observed. However, little is known about interleukin (IL)-17 and Th17 responses in sarcoidosis. Here, we investigated the levels of IL-17 and frequencies of IL-17-producing cells responding to mKatG in sarcoidosis patients with different prognosis. Peripheral blood and bronchoalveolar lavage (BAL) cells were obtained from sarcoidosis patients with or without Lofgren's syndrome (often associated with spontaneous recovery), and also stratified according to human leucocyte antigen (HLA) type. Cells producing IL-17 and interferon (IFN)-gamma after stimulation with mKatG were enumerated by enzyme-linked immunospot (ELISPOT). The level of IL-17 in the BAL fluid of sarcoidosis patients and healthy controls was measured by quantitative immuno-polymerase chain reaction (qIPCR). We also performed flow cytometry and immunohistochemistry for further characterization of IL-17 expression. Patients with Lofgren's syndrome had a higher frequency of IL-17-producing cells responding to mKatG in BAL fluid compared to patients without Lofgren's syndrome (P < 0.05). The HLA-DR3(+) sarcoidosis patients with Lfgren's syndrome (known to have a particularly good prognosis) also had a clearly higher level of IL-17 in BAL fluid compared to healthy controls and sarcoidosis patients without Lofgren's syndrome (P < 0.01) and (P < 0.05), respectively. No such difference between patient groups was observed with regard to IFN-gamma and not with regard to either cytokine in peripheral blood. These findings suggest that IL-17-producing cells may be a useful biomarker for the prognosis of sarcoidosis and play a role in the spontaneous recovery typical of patients with Lfgren's syndrome.
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| 16. |
- Sorensen, SL, et al.
(author)
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Femtosecond pump-probe photoelectron spectroscopy of predissociative Rydberg states in acetylene
- 2000
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In: JOURNAL OF CHEMICAL PHYSICS. - : AMER INST PHYSICS. - 0021-9606. ; 112:18, s. 8038-8042 Language: English
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Journal article (peer-reviewed)abstract
- We employ a pump-probe approach to molecular photoionization to study fast dissociation of Rydberg states in acetylene. By using time-resolved photoelectron spectroscopy to study the electronic state of the resulting ions we are able to monitor the system
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| 17. |
- Wahlstrom, I., et al.
(author)
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Projected climate change impact on a coastal sea-As significant as all current pressures combined
- 2022
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In: Global Change Biology. - : Wiley. - 1354-1013 .- 1365-2486. ; 28:17, s. 5310-5319
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Journal article (peer-reviewed)abstract
- Climate change influences the ocean's physical and biogeochemical conditions, causing additional pressures on marine environments and ecosystems, now and in the future. Such changes occur in environments that already today suffer under pressures from, for example, eutrophication, pollution, shipping, and more. We demonstrate how to implement climate change into regional marine spatial planning by introducing data of future temperature, salinity, and sea ice cover from regional ocean climate model projections to an existing cumulative impact model. This makes it possible to assess climate change impact in relation to pre-existing cumulative impact from current human activities. Results indicate that end-of-century projected climate change alone is a threat of the same magnitude as the combination of all current pressures to the marine environment. These findings give marine planners and policymakers forewarning on how future climate change may impact marine ecosystems, across space, emission scenarios, and in relation to other pressures.
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