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1.
  • Jakosky, B. M., et al. (författare)
  • MAVEN observations of the response of Mars to an interplanetary coronal mass ejection
  • 2015
  • Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 350:6261
  • Tidskriftsartikel (refereegranskat)abstract
    • Coupling between the lower and upper atmosphere, combined with loss of gas from the upper atmosphere to space, likely contributed to the thin, cold, dry atmosphere of modern Mars. To help understand ongoing ion loss to space, the Mars Atmosphere and Volatile Evolution (MAVEN) spacecraft made comprehensive measurements of the Mars upper atmosphere, ionosphere, and interactions with the Sun and solar wind during an interplanetary coronal mass ejection impact in March 2015. Responses include changes in the bow shock and magnetosheath, formation of widespread diffuse aurora, and enhancement of pick-up ions. Observations and models both show an enhancement in escape rate of ions to space during the event. Ion loss during solar events early in Mars history may have been a major contributor to the long-term evolution of the Mars atmosphere.
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2.
  • Adlarson, Patrik, et al. (författare)
  • Investigation of the dd -> (3)Hen pi(0) reaction with the FZ Julich WASA-at-COSY facility
  • 2013
  • Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 88:1, s. 014004-
  • Tidskriftsartikel (refereegranskat)abstract
    • An exclusive measurement of the dd -> (3)Hen pi(0) reaction was carried out at a beam momentum of p(d) = 1.2 GeV/c using the WASA-at-COSY facility. Information on the total cross section as well as differential distributions was obtained. The data are described by a phenomenological approach based on a combination of a quasifree model and a partial wave expansion for the three-body reaction. The total cross section is found to be sigma(tot) = ( 2.89 +/- 0.01(stat) +/- 0.06(sys) +/- 0.29(norm)) mu b. The contribution of the quasifree processes ( with the beam or target neutron being a spectator) accounts for 38% of the total cross section and dominates the differential distributions in specific regions of phase space. The remaining part of the cross section can be described by a partial wave decomposition indicating the significance of p-wave contributions in the final state.
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3.
  • Adlarson, Patrik, et al. (författare)
  • Measurement of the pn -> pp pi(0)pi(-) reaction in search for the recently observed resonance structure in d pi(0)pi(0) and d pi(+)pi(-) systems
  • 2013
  • Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 88:5, s. 055208-
  • Tidskriftsartikel (refereegranskat)abstract
    • Exclusive measurements of the quasifree pn -> pp pi(0)pi(-) reaction have been performed by means of pd collisions at T-p = 1.2 GeV using the wide angle shower apparatus (WASA) detector setup at the cooler synchrotron COSY (Institut fur Kernphysik, Julich). Total and differential cross sections have been obtained covering the energy region root s = (2.35-2.46) GeV, which includes the region of the ABC effect and its associated resonance structure. NoABCeffect, i.e., low-mass enhancement is found in the pi(0)pi(-) -invariant mass spectrum, in agreement with the constraint from Bose statistics that the isovector pion pair can not be in relative s wave. At the upper end of the covered energy region t-channel processes for Roper, Delta(1600) and Delta Delta excitations provide a reasonable description of the data, but at low energies the measured cross sections are much larger than predicted by such processes. Adding a resonance amplitude for the resonance at m = 2.37 GeV with Gamma = 70 MeV and I (J(P)) = 0(3(+)) observed recently in pn -> d pi(0)pi(0) and pn -> d pi(+)pi(-) reactions leads to an agreement with the data also at low energies.
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4.
  • Adlarson, Patrik, et al. (författare)
  • Cross section ratio and angular distributions of the reaction p + d -> He-3 + eta at 48.8MeV and 59.8MeV excess energy
  • 2014
  • Ingår i: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-6001 .- 1434-601X. ; 50:6, s. 100-
  • Tidskriftsartikel (refereegranskat)abstract
    • We present new data for angular distributions and on the cross section ratio of the p+d -> He-3+eta reaction at excess energies of Q - 48.8MeV and Q - 59.8 MeV. The data have been obtained at the WASA-at-COSY experiment (Forschungszentrum Julich) using a proton beam and a deuterium pellet target. While the shape of obtained angular distributions show only a slow variation with the energy, the new results indicate a distinct and unexpected total cross section fluctuation between Q = 20MeV and Q = 60 MeV, which might indicate the variation of the production mechanism within this energy interval.
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5.
  • Adlarson, Patrik, et al. (författare)
  • Differential cross sections for neutron-proton scattering in the region of the d* (2380) dibaryon resonance
  • 2020
  • Ingår i: Physical Review C. Nuclear Physics. - : AMER PHYSICAL SOC. - 0556-2813 .- 1089-490X. ; 102:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Differential cross sections have been extracted from exclusive and kinematically complete high-statistics measurements of quasifree polarized (n) over barp scattering performed in the energy region of the d* (2380) dibaryon resonance covering the range of beam energies T-n = 0.98-1.29 GeV (root s = 2.32-2.44 GeV). The experiment was carried out with the WASA-at-COSY setup having a polarized deuteron beam impinged on the hydrogen pellet target and utilizing the quasifree process dp -> np + p(spectator). In this way the np differential cross section sigma (Theta) was measured over a large angular range. The obtained angular distributions complement the corresponding analyzing power A(y)(Theta) measurements published previously. A SAID partial-wave analysis incorporating the new data strengthens the finding of a resonance pole in the coupled D-3(3) - (3)G(3) waves.
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6.
  • Adlarson, Patrik, et al. (författare)
  • Evidence for a New Resonance from Polarized Neutron-Proton Scattering
  • 2014
  • Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 112:20, s. 202301-
  • Tidskriftsartikel (refereegranskat)abstract
    • Exclusive and kinematically complete high-statistics measurements of quasifree polarized (n) over right arrowp scattering have been performed in the energy region of the narrow resonancelike structure d* with I(J(P)) = 0(3(+)),M approximate to 2380 MeV, and Gamma approximate to 70 MeV observed recently in the double-pionic fusion channels pn -> d pi(0)pi(0) and pn -> d pi(+)pi(-). The experiment was carried out with the WASA detector setup at COSY having a polarized deuteron beam impinged on the hydrogen pellet target and utilizing the quasifree process (d) over right arrowp -> np + p(spectator). This allowed the np analyzing power, A(y), to be measured over a broad angular range. The obtained A(y) angular distributions deviate systematically from the current SAID SP07 NN partial-wave solution. Incorporating the new A(y) data into the SAID analysis produces a pole in the D-3(3) - (3)G(3) waves in support of the d* resonance hypothesis.
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7.
  • Adlarson, P., et al. (författare)
  • Isospin decomposition of the basic double-pionic fusion in the region of the ABC effect
  • 2013
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 721:4-5, s. 229-236
  • Tidskriftsartikel (refereegranskat)abstract
    • Exclusive and kinematically complete high-statistics measurements of the basic double-pionic fusion reactions pn -> d pi(0)pi(0), pn -> d pi(+)pi(-) and pp -> d pi(+)pi(0) have been carried out simultaneously over the energy region of the ABC effect using the WASA detector setup at COSY. Whereas the isoscalar reaction part given by the d pi(0)pi(0) channel exhibits the ABC effect, i.e. a low-mass enhancement in the pi pi-invariant mass distribution, as well as the associated resonance structure in the total cross section, the isovector part given by the d pi(+)pi(0) channel shows a smooth behavior consistent with the conventional t-channel Delta Delta process. The d pi(+)pi(-) data are very well reproduced by combining the data for isovector and isoscalar contributions, if the kinematical consequences of the isospin violation due to different masses for charged and neutral pions are taken into account.
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8.
  • Adlarson, Patrik, et al. (författare)
  • Neutron-proton scattering in the context of the d*(2380) resonance
  • 2014
  • Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 90:3, s. 035204-
  • Tidskriftsartikel (refereegranskat)abstract
    • New data on quasifree polarized neutron-proton scattering in the region of the recently observed d* resonance structure are obtained by exclusive and kinematically complete high-statistics measurements with WASA at COSY. This paper details the determination of the beam polarization, checks of the quasifree character of the scattering process, on all obtained Ay angular distributions and on the new partial-wave analysis, which includes the new data producing a resonance pole in D-3(3)-(3)G(3) coupled partial waves at (2380 +/- 10 - i40 +/- 5) MeV-in accordance with the d* dibaryon resonance hypothesis. The effect of the new partial-wave solution on the description of total and differential cross-section data as well as specific combinations of spin-correlation and spin-transfer observables available from COSY-ANKE measurements at T-d = 2.27 GeV is discussed.
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9.
  • Adlarson, Patrik, et al. (författare)
  • Search for eta-mesic He-4 with the WASA-at-COSY detector
  • 2013
  • Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 87:3, s. 035204-
  • Tidskriftsartikel (refereegranskat)abstract
    • An exclusive measurement of the excitation function for the dd -> (3)Hep pi(-) reaction was performed at the Cooler Synchrotron COSY-Julich with the WASA-at-COSY detection system. The data were taken during a slow acceleration of the beam from 2.185 to 2.400 GeV/c crossing the kinematic threshold for the eta-meson production in the dd -> He-4 eta reaction at 2.336 GeV/c. The corresponding excess energy with respect to the He-4-eta system varied from -51.4 to 22 MeV. The integrated luminosity in the experiment was determined using the dd -> (3)Hen reaction. The shape of the excitation function for the dd -> (3)Hep pi(-) reaction was examined. No signal of the He-4-eta bound state was observed. An upper limit for the cross section for the bound state formation and decay in the process dd -> (He-4-eta)(bound) -> (3)Hep pi(-) was determined on the 90% confidence level and it varies from 20 to 27 nb for the bound state width ranging from 5 to 35 MeV, respectively. 
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10.
  • Adlarson, Patrik, et al. (författare)
  • Measurement of the eta -> pi(+)pi(-)pi(0) Dalitz plot distribution
  • 2014
  • Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 90:4, s. 045207-
  • Tidskriftsartikel (refereegranskat)abstract
    • The Dalitz plot distribution of the eta -> pi(+)pi(-)pi(0) decay is determined by using a data sample of 1.2 x 10(7) eta mesons from the pd -> He-3 eta reaction at 1 GeV collected by the WASA detector at COSY.
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11.
  • Jakosky, B. M., et al. (författare)
  • The Mars Atmosphere and Volatile Evolution (MAVEN) Mission
  • 2015
  • Ingår i: Space Science Reviews. - : Springer Science and Business Media LLC. - 0038-6308 .- 1572-9672. ; 195:1-4, s. 3-48
  • Forskningsöversikt (refereegranskat)abstract
    • The MAVEN spacecraft launched in November 2013, arrived at Mars in September 2014, and completed commissioning and began its one-Earth-year primary science mission in November 2014. The orbiter's science objectives are to explore the interactions of the Sun and the solar wind with the Mars magnetosphere and upper atmosphere, to determine the structure of the upper atmosphere and ionosphere and the processes controlling it, to determine the escape rates from the upper atmosphere to space at the present epoch, and to measure properties that allow us to extrapolate these escape rates into the past to determine the total loss of atmospheric gas to space through time. These results will allow us to determine the importance of loss to space in changing the Mars climate and atmosphere through time, thereby providing important boundary conditions on the history of the habitability of Mars. The MAVEN spacecraft contains eight science instruments (with nine sensors) that measure the energy and particle input from the Sun into the Mars upper atmosphere, the response of the upper atmosphere to that input, and the resulting escape of gas to space. In addition, it contains an Electra relay that will allow it to relay commands and data between spacecraft on the surface and Earth.
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12.
  • Adlarson, Patrik, et al. (författare)
  • ABC effect and resonance structure in the double-pionic fusion to He-3
  • 2015
  • Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 91:1, s. 015201-
  • Tidskriftsartikel (refereegranskat)abstract
    • Exclusive and kinematically complete measurements of the double pionic fusion to He-3 have been performed in the energy region of the so-called ABC effect, which denotes a pronounced low-mass enhancement in the pi pi-invariant mass spectrum. The experiments were carried out with the WASA detector setup at COSY (the cooler synchrotron at Forschungszentrum Julich). Similar to the observations in the basic pn -> d pi(0)pi(0) reaction and in the dd -> He-4 pi(0)pi(0) reaction, the data reveal a correlation between the ABC effect and a resonance-like energy dependence in the total cross section. Differential cross sections are well described by the hypothesis of d* resonance formation during the reaction process in addition to the conventional t-channel Delta Delta mechanism. The deduced d* resonance width can be understood from collision broadening due to Fermi motion of the nucleons in initial and final nuclei.
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13.
  • Adlarson, Patrik, et al. (författare)
  • Charge symmetry breaking in dd -> He-4 pi(0) with WASA-at-COSY
  • 2014
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 739, s. 44-49
  • Tidskriftsartikel (refereegranskat)abstract
    • Charge symmetry breaking (CSB) observables are a suitable experimental tool to examine effects induced by quark masses on the nuclear level. Previous high precision data from TRIUMF and IUCF are currently used to develop a consistent description of CSB within the framework of chiral perturbation theory. In this work the experimental studies on the reaction dd -> He-4 pi(0) have been extended towards higher excess energies in order to provide information on the contribution of p-waves in the final state. For this, an exclusive measurement has been carried out at a beam momentum of p(d) = 1.2GeV/c using the WASA-at-COSY facility. The total cross section amounts to sigma(tot) =(118 +/- 18(stat) +/- 13(sys) +/- 8(ext)) p band first data on the differential cross section are consistent with s-wave pion production.
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14.
  • Adlarson, Patrik, et al. (författare)
  • Measurements of branching ratios for eta decays into charged particles
  • 2016
  • Ingår i: PHYSICAL REVIEW C. - 2469-9985. ; 94:6
  • Tidskriftsartikel (refereegranskat)abstract
    • The WASA-at-COSY experiment has collected 3 x 10(7) events with eta mesons produced via the reaction pd -> He-3 eta at T = 1.0 GeV. Using this data set, we evaluate the branching ratios of the decays eta -> pi(+)pi(-)gamma, eta -> e(+)e(-)gamma, eta -> pi(+)pi(-)e(+)e(-), and eta -> e(+)e(-)e(+)e(-). The branching ratios are normalized to the eta -> pi(+)pi(-) pi(0) decay. In addition an upper limit on a CP-violating asymmetry in eta -> pi(+)pi(-)e(+)e(-) is extracted.
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15.
  • Adlarson, Patrik, et al. (författare)
  • Search for eta-mesic He-4 in the dd -> (3)Hen pi(0) and dd -> (3)Hep pi(-) reactions with the WASA-at-COSY facility
  • 2017
  • Ingår i: Nuclear Physics A. - : ELSEVIER SCIENCE BV. - 0375-9474 .- 1873-1554. ; 959, s. 102-115
  • Tidskriftsartikel (refereegranskat)abstract
    • The search for He-4-eta bound states was performed with the WASA-at-COSY facility via the measurement of the excitation function for the dd -> (3)Hen pi(0) and dd -> (3)Hep pi(-) processes. The deuteron beam momentum was varied continuously between 2.127 GeV/c and 2.422 GeV/c, corresponding to the excess energy for the dd -> He-4 eta reaction ranging from Q = 70 MeV to Q = 30 MeV. The luminosity was determined based on the dd -> (3)Hen reaction and the quasi-free proton proton scattering via dd -> ppn(spectator)n(spectator) reactions. The excitation functions, determined independently for the measured reactions, do not reveal a structure which could be interpreted as a narrow mesic nucleus. Therefore, the upper limits of the total cross sections for the bound state production and decay in dd -> (4He-eta)(bound) -> (3)Hen pi(0) and dd -> (He-4-eta)(bound) -> (3)Hep pi(-) processes were determined taking into account the isospin relation between the both of the considered channels. The results of the analysis depend on the assumptions of the N* (1535) momentum distribution in the anticipated mesic-He-4. Assuming, as in the previous works, that this is identical with the distribution of nucleons bound with 20 MeV in He-4, we determined that (for the mesic bound state width in the range from 5 MeV to 50 MeV) the upper limits at 90% confidence level are about 3 nb and about 6 nb for n pi(0) and p pi(-) channels, respectively. However, based on the recent theoretical findings of the N*(1535) momentum distribution in the N*-He-3 nucleus bound by 3.6 MeV, we find that the WASA-at-COSY detector acceptance decreases and hence the corresponding upper limits are 5 nb and 10 nb for n pi(0) and p pi(-) channels respectively. (C) 2017 Elsevier B.V. All rights reserved.
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16.
  • Adlarsona, Patrik, et al. (författare)
  • Measurement of the np -> np pi(0)pi(0) reaction in search for the recently observed d* (2380) resonance
  • 2015
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 743, s. 325-332
  • Tidskriftsartikel (refereegranskat)abstract
    • Exclusive measurements of the quasi-free np --> np pi(0)pi(0) reaction have been performed by means of dp collisions at T-d = 2.27 GeV using the WASA detector setup at COSY. Total and differential cross sections have been obtained covering the energy region root s = (2.35-2.46) GeV, which includes the region of the ABC effect and its associated d* (2380) resonance. Adding the d* resonance amplitude to that for the conventional processes leads to a reasonable description of the data. The observed resonance effect in the total cross section is in agreement with the predictions of Faldt and Wilkin as well with those of Albadajedo and Oset. The ABC effect, i.e. the low-mass enhancement in the pi(0)pi(0)-invariant mass spectrum, is found to be very modest - if present at all, which might pose a problem to some of its interpretations.
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17.
  • Betti, M. G., et al. (författare)
  • Neutrino physics with the PTOLEMY project : active neutrino properties and the light sterile case
  • 2019
  • Ingår i: Journal of Cosmology and Astroparticle Physics. - : IOP PUBLISHING LTD. - 1475-7516. ; :7
  • Tidskriftsartikel (refereegranskat)abstract
    • The PTOLEMY project aims to develop a scalable design for a Cosmic Neutrino Background (CNB) detector, the first of its kind and the only one conceived that can look directly at the image of the Universe encoded in neutrino background produced in the first second after the Big Bang. The scope of the work for the next three years is to complete the conceptual design of this detector and to validate with direct measurements that the non-neutrino backgrounds are below the expected cosmological signal. In this paper we discuss in details the theoretical aspects of the experiment and its physics goals. In particular, we mainly address three issues. First we discuss the sensitivity of PTOLEMY to the standard neutrino mass scale. We then study the perspectives of the experiment to detect the CNB via neutrino capture on tritium as a function of the neutrino mass scale and the energy resolution of the apparatus. Finally, we consider an extra sterile neutrino with mass in the eV range, coupled to the active states via oscillations, which has been advocated in view of neutrino oscillation anomalies. This extra state would contribute to the tritium decay spectrum, and its properties, mass and mixing angle, could be studied by analyzing the features in the beta decay electron spectrum.
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18.
  • Denomme-Pichon, AS, et al. (författare)
  • Solve-RD: the ITHACA perspective
  • 2022
  • Ingår i: EUROPEAN JOURNAL OF HUMAN GENETICS. - 1018-4813. ; 30:SUPPL 1, s. 236-237
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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19.
  • Adlarson, Patrik, et al. (författare)
  • Backward single-pion production in the pd -> He-3 pi(0)reaction with WASA-at-COSY
  • 2018
  • Ingår i: European Physical Journal A. - : SPRINGER. - 1434-6001 .- 1434-601X. ; 54:9
  • Tidskriftsartikel (refereegranskat)abstract
    • New data on the production of single neutral pions in the pd -> He-3 pi(0) reaction are presented. For fifteen proton beam momenta between p(p) = 1.60GeV/c and p(p) = 1.74 GeV/c, differential cross sections are determined over a large fraction of the backward hemisphere. Since the only previous systematic measurements of single-pion production at these energies were made in collinear kinematics, the present work constitutes a significant extension of the current knowledge on this reaction. Even this far above the production threshold, significant changes are found in the behaviour of the angular distributions over small intervals in beam momentum.
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20.
  • Adlarson, Patrik, et al. (författare)
  • Examination of the production of an isotensor dibaryon in the pp -> pp pi(+)pi(-) reaction
  • 2019
  • Ingår i: Physical Review C. - : AMER PHYSICAL SOC. - 2469-9985 .- 2469-9993. ; 99:2
  • Tidskriftsartikel (refereegranskat)abstract
    • The quasifree pp -> pp pi(+)pi(-) reaction has been measured by means of pd collisions at T-p = 1.2 GeV using the WASA detector setup at COSY enabling exclusive and kinematically complete measurements. Total and differential cross sections have been extracted for the energy region T-p = 1.08-1.36 GeV (root s = 2.35-2.46 GeV) covering thus the regions of N* (1440 ) and Delta(1232)Delta(1232) resonance excitations. Calculations describing these excitations by t-channel meson exchange as well as isospin relations based on the pp -> pp pi(0)pi(0) data underpredict substantially the measured total cross section. The calculations are also at variance with specific experimental differential cross sections. An isotensor Delta N dibaryon resonance with I(J(P)) = 2(1(+) ) produced associatedly with a pion is able to overcome these deficiencies. Such a dibaryon was predicted by Dyson and Xuong [Phys. Rev. Lett. 13, 815 (1964)] and more recently calculated by A. Gal and H. Garcilazo [Nucl. Phys. A 928, 73 (2014)].
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21.
  • Adlarson, Patrik, et al. (författare)
  • Importance of d-wave contributions in the charge symmetry breaking reaction dd -> He-4 pi(0)
  • 2018
  • Ingår i: Physics Letters B. - : ELSEVIER SCIENCE BV. - 0370-2693 .- 1873-2445. ; 781, s. 645-650
  • Tidskriftsartikel (refereegranskat)abstract
    • This letter reports a first quantitative analysis of the contribution of higher partial waves in the charge symmetry breaking reaction dd -> He-4 pi(0) using the WASA-at-COSY detector setup at an excess energy of Q = 60 MeV. The determined differential cross section can be parametrized as d sigma/d Omega = a + b cos(2) theta*, where theta* is the production angle of the pion in the center-of-mass coordinate system, and the results for the parameters are a = (1.55 +/- 0.46(stat)(-0.8)(+0.32)(syst)) pb/sr and b = (13.1 +/- 2.1(stat)(-2.7)(+1.0)(syst)) pb/sr. The data are compatible with vanishing p-waves and a sizable d-wave contribution. This finding should strongly constrain the contribution of the A isobar to the dd -> He-4 pi(0) reaction and is, therefore, crucial for a quantitative understanding of quark mass effects in nuclear production reactions.
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22.
  • Adlarson, Patrik, et al. (författare)
  • Isotensor Dibaryon in the pp -> pp pi(+)pi(-) Reaction?
  • 2018
  • Ingår i: Physical Review Letters. - : AMER PHYSICAL SOC. - 0031-9007 .- 1079-7114. ; 121:5
  • Tidskriftsartikel (refereegranskat)abstract
    • Exclusive measurements of the quasifree pp -> pp pi(+)pi(-) reaction have been carried out at WASA@ COSY by means of pd collisions at T-p = 1.2 GeV. Total and differential cross sections have been extracted covering the energy region T-p = 1.08-1.36 GeV, which is the region of N* (1440) and Delta(123)Delta(1232) resonance excitations. Calculations describing these excitations by t-channel meson exchange are at variance with the measured differential cross sections and underpredict substantially the experimental total cross section. An isotensor Delta N dibaryon resonance with I(J(P)) = 2(1(+)) produced associatedly with a pion is able to overcome these deficiencies.
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23.
  • Adlarson, Patrik, et al. (författare)
  • Measurement of the (n)over-right-arrowp -> d pi(0) pi(0) reaction with polarized beam in the region of the d(*)(2380) resonance
  • 2016
  • Ingår i: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-6001 .- 1434-601X. ; 52:5, s. 1-7
  • Tidskriftsartikel (refereegranskat)abstract
    • We report on a high-statistics measurement of the most basic double-pionic fusion reaction over the energy region of the d (*)(2380) resonance by use of a polarized deuteron beam and observing the double fusion reaction in the quasifree scattering mode. The measurements were performed with the WASA detector setup at COSY. The data reveal substantial analyzing powers and confirm conclusions about the d(*) resonance obtained from unpolarized measurements. We also confirm the previous unpolarized data obtained under complementary kinematic conditions.
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24.
  • Adlarson, Patrik, et al. (författare)
  • Measurement of the ω → π+π−π0 Dalitz plot distribution : The WASA-at-COSY Collaboration
  • 2017
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 770, s. 418-425
  • Tidskriftsartikel (refereegranskat)abstract
    • Using the production reactions pd -> He-3 omega and pp -> pp omega, the Dalitz plot distribution for the omega -> pi(+)pi(-)pi(0)decay is studied with the WASA detector at COSY, based on a combined data sample of (4.408 +/- 0.042) x 10(4) events. The Dalitz plot density is parametrised by a product of the P-wave phase space and a polynomial expansion in the normalised polar Dalitz plot variables Z and phi. For the first time, a deviation from pure P-wave phase space is observed with a significance of 4.1 sigma. The deviation is parametrised by a linear term 1+2 alpha Z, with alpha determined to be +0.147 +/- 0.036, consistent with the expectations of rho-meson-type final-state interactions of the P-wave pion pairs. (C) 2017 The Author. Published by Elsevier B.V.
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25.
  • Adlarson, Patrik, et al. (författare)
  • Search for an isospin I=3 dibaryon
  • 2016
  • Ingår i: Physics Letters B. - : ELSEVIER SCIENCE BV. - 0370-2693 .- 1873-2445. ; 762, s. 455-461
  • Tidskriftsartikel (refereegranskat)abstract
    • Various theoretical calculations based on QCD or hadronic interactions predict that in addition to the recently observed dibaryon resonance d*(2380) with I(J(P)) = 3(0(+)) there should also exist a dibaryon resonance with mirrored quantum numbers I(J(P)) = 3(0(+)). We report here on a search for such a NN-decoupled state in data on the pp -> pp pi(+) pi(+) pi(-) pi(-) reaction. Since no clear-cut evidence has been found, we give upper limits for the production cross section of such a resonance in the mass range 2280-2500 MeV.
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26.
  • Adlarson, Patrik, et al. (författare)
  • Search for C violation in the decay eta -> pi(0)e(+)e(-) with WASA-at-COSY
  • 2018
  • Ingår i: Physics Letters B. - : ELSEVIER SCIENCE BV. - 0370-2693 .- 1873-2445. ; 784, s. 378-384
  • Tidskriftsartikel (refereegranskat)abstract
    • We report on the search for the rare decay eta -> pi(0)e(+)e(-) which is of interest to study C violation in the electromagnetic interaction which would indicate contributions from physics beyond the Standard Model, since the allowed decay via a two-photon intermediate state is strongly suppressed. The experiment has been performed using the WASA-at-COSY installation, located at the COSY accelerator of the Forschungszentrum Julich, Germany. In total 3 x 10(7) events of the reaction pd -> He-3 eta have been recorded at an excess energy of Q = 59.8MeV. Based on this data set the C parity violating decay eta -> pi(0)gamma* -> pi(0)e(+)e(-) via a single-photon intermediate state has been searched for, resulting in new upper limits of Gamma(eta -> pi(0)e(+) e(-))/Gamma(eta -> pi(+) pi(-) pi(0)) < 3.28 x 10(-5) and Gamma(eta -> pi(0)e(+) e(-))/Gamma(eta -> all)< 7.5 x 10(-6) (CL=90%), respectively. 
  •  
27.
  • Adlarson, Patrik, et al. (författare)
  • Search for the eta mesic He-3 in the pd -> dp pi(0) reaction with the WASA-at-COSY facility
  • 2020
  • Ingår i: Physical Review C. Nuclear Physics. - : AMER PHYSICAL SOC. - 0556-2813 .- 1089-490X. ; 102:4
  • Tidskriftsartikel (refereegranskat)abstract
    • The excitation function for the pd -> dp pi(0) reaction has been measured byWASA-at-COSY experiment with the aim of searching for He-3-h mesic nuclei. The measurement in the vicinity of h meson production was performed using a ramped proton beam. The data analysis and interpretation was carried out with the assumption that the h mesic helium decays via the formation of an intermediate N*(1535) resonance. No direct signal of the. mesic nucleus is observed in the excitation function. We determine a new improved upper limit for the total cross section for the bound state production and decay in the pd -> (He-3-eta)(bound) -> dp pi(0) process. It varies between 13 nb to 24 nb for the bound state with width in the range Gamma is an element of ( 5, 50) MeV.
  •  
28.
  • Adlarson, Patrik, et al. (författare)
  • Search for η mesic 3He with the WASA-at-COSY facility in the pd -> 3He2γ and pd -> 3He6γ  reaction
  • 2020
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 802
  • Tidskriftsartikel (refereegranskat)abstract
    • We report on the experimental search for the bound state of an eta meson and He-3 nucleus performed using the WASA-at-COSY detector setup. In order to search for the eta-mesic nucleus decay, the pd -> (3)He2(gamma) and pd -> (3)He6 gamma channels have been analysed. These reactions manifest the direct decay of the ti meson bound in a He-3 nucleus. This non-mesonic decay channel has been considered for the first time. When taking into account only statistical errors, the obtained excitation functions reveal a slight indication for a possible bound state signal corresponding to a He-3-eta nucleus width Gamma above 20 MeV and binding energy B-s between 0 and 15 MeV. However, the determined cross sections are consistent with zero in the range of the systematic uncertainty. Therefore, as final result we estimate only the upper limit for the cross section of the eta-mesic He-3 nucleus formation followed by the eta meson decay which varies between 2 nb and 15 nb depending on possible bound state parameters.
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29.
  • Adlarson, Patrik, et al. (författare)
  • Spin Dependence of eta Meson Production in Proton-Proton Collisions Close to Threshold
  • 2018
  • Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 120:2
  • Tidskriftsartikel (refereegranskat)abstract
    • Taking advantage of the high acceptance and axial symmetry of the WASA-at-COSY detector, and the high polarization degree of the proton beam of COSY, the reaction →pp→ppη has been measured close to threshold to explore the analyzing power Ay. The angular distribution of Ay is determined with the precision improved by more than 1 order of magnitude with respect to previous results, allowing a first accurate comparison with theoretical predictions. The determined analyzing power is consistent with zero for an excess energy of Q=15  MeV, signaling s-wave production with no evidence for higher partial waves. At Q=72  MeV the data reveal strong interference of Ps and Pp partial waves and cancellation of (Pp)2 and Ss∗Sd contributions. These results rule out the presently available theoretical predictions for the production mechanism of the η meson.
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30.
  • Adlarson, Patrik, et al. (författare)
  • Three-nucleon dynamics in dp breakup collisions using the WASA detector at COSY-Julich
  • 2020
  • Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 101:4
  • Tidskriftsartikel (refereegranskat)abstract
    • The differential cross section for the H-1(d, pp)n breakup reaction at deuteron beam energy of 340 MeV has been measured with the use of the WASA detector at COSY-Jillich. The set of proton-proton coincidences registered at the Forward Detector has been analyzed on a dense grid of kinematic variables, giving in total around 5600 data points. The cross-section data are compared to theoretical predictions based on the state-ofthe-art nucleon-nucleon potentials, combined with a three-nucleon force or the Coulomb interaction or carried out in a relativistic regime.
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31.
  • Adlarson, Patrik, et al. (författare)
  • Total and differential cross sections of η-production in proton–deuteron fusion for excess energies between Qη = 13 MeV and Qη = 81 MeV
  • 2018
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 782, s. 297-304
  • Tidskriftsartikel (refereegranskat)abstract
    • New data on both total and differential cross sections of the production of eta mesons in proton-deuteron fusion to He-3 eta in the excess energy region 13.6 MeV <= Q(eta) <= 80.9 MeV are presented. These data have been obtained with the WASA-at-COSY detector setup located at the Forschungszentrum Julich, using a proton beam at 15 different beam momenta between p(p) = 1.60 GeV/c and p(p) = 1.74 GeV/c. While significant structure of the total cross section is observed in the energy region 20 MeV less than or similar to Q(eta) less than or similar to 60 MeV, a previously reported sharp variation around Q(eta) approximate to 50 MeV cannot be confirmed. Angular distributions show the typical forward- peaking that was noted earlier. For the first time, it is possible to study the development of these angular distributions with rising excess energy over a wide interval.
  •  
32.
  • Antel, C., et al. (författare)
  • Feebly-interacting particles : FIPs 2022 Workshop Report
  • 2023
  • Ingår i: European Physical Journal C. - : Springer. - 1434-6044 .- 1434-6052. ; 83:12
  • Forskningsöversikt (refereegranskat)abstract
    • Particle physics today faces the challenge of explaining the mystery of dark matter, the origin of matter over anti-matter in the Universe, the origin of the neutrino masses, the apparent fine-tuning of the electro-weak scale, and many other aspects of fundamental physics. Perhaps the most striking frontier to emerge in the search for answers involves new physics at mass scales comparable to familiar matter, below the GeV-scale, or even radically below, down to sub-eV scales, and with very feeble interaction strength. New theoretical ideas to address dark matter and other fundamental questions predict such feebly interacting particles (FIPs) at these scales, and indeed, existing data provide numerous hints for such possibility. A vibrant experimental program to discover such physics is under way, guided by a systematic theoretical approach firmly grounded on the underlying principles of the Standard Model. This document represents the report of the FIPs 2022 workshop, held at CERN between the 17 and 21 October 2022 and aims to give an overview of these efforts, their motivations, and the decadal goals that animate the community involved in the search for FIPs.
  •  
33.
  • Betti, M. G., et al. (författare)
  • A design for an electromagnetic filter for precision energy measurements at the tritium endpoint
  • 2019
  • Ingår i: Progress in Particle and Nuclear Physics. - : Elsevier BV. - 0146-6410 .- 1873-2224. ; 106, s. 120-131
  • Forskningsöversikt (refereegranskat)abstract
    • We present a detailed description of the electromagnetic filter for the PTOLEMY project to directly detect the Cosmic Neutrino Background (CNB). Starting with an initial estimate for the orbital magnetic moment, the higher-order drift process of E x B is configured to balance the gradient-B drift motion of the electron in such a way as to guide the trajectory into the standing voltage potential along the mid-plane of the filter. As a function of drift distance along the length of the filter, the filter zooms in with exponentially increasing precision on the transverse velocity component of the electron kinetic energy. This yields a linear dimension for the total filter length that is exceptionally compact compared to previous techniques for electromagnetic filtering. The parallel velocity component of the electron kinetic energy oscillates in an electrostatic harmonic trap as the electron drifts along the length of the filter. An analysis of the phase-space volume conservation validates the expected behavior of the filter from the adiabatic invariance of the orbital magnetic moment and energy conservation following Liouville's theorem for Hamiltonian systems.
  •  
34.
  • Hempelmann, N., et al. (författare)
  • Phase measurement for driven spin oscillations in a storage ring
  • 2018
  • Ingår i: Physical Review Accelerators and Beams. - : American Physical Society. - 2469-9888. ; 21:4
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper reports the first simultaneous measurement of the horizontal and vertical components of the polarization vector in a storage ring under the influence of a radio frequency (rf) solenoid. The experiments were performed at the Cooler Synchrotron COSY in Julich using a vector polarized, bunched 0.97 GeV/c deuteron beam. Using the new spin feedback system, we set the initial phase difference between the solenoid field and the precession of the polarization vector to a predefined value. The feedback system was then switched off, allowing the phase difference to change over time, and the solenoid was switched on to rotate the polarization vector. We observed an oscillation of the vertical polarization component and the phase difference. The oscillations can be described using an analytical model. The results of this experiment also apply to other rf devices with horizontal magnetic fields, such as Wien filters. The precise manipulation of particle spins in storage rings is a prerequisite for measuring the electric dipole moment (EDM) of charged particles.
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35.
  • Hempelmann, N., et al. (författare)
  • Locking the Spin Precession in a Storage Ring
  • 2017
  • Ingår i: Physical Review Letters. - : American Physical Society. - 0031-9007 .- 1079-7114. ; 119:1
  • Tidskriftsartikel (refereegranskat)abstract
    • This Letter reports the successful use of feedback from a spin polarization measurement to the revolution frequency of a 0.97 GeV= c bunched and polarized deuteron beam in the Cooler Synchrotron (COSY) storage ring in order to control both the precession rate (approximate to 121 kHz) and the phase of the horizontal polarization component. Real time synchronization with a radio frequency (rf) solenoid made possible the rotation of the polarization out of the horizontal plane, yielding a demonstration of the feedback method to manipulate the polarization. In particular, the rotation rate shows a sinusoidal function of the horizontal polarization phase (relative to the rf solenoid), which was controlled to within a 1 standard deviation range of sigma= 0.21 rad. The minimum possible adjustment was 3.7 mHz out of a revolution frequency of 753 kHz, which changes the precession rate by 26 mrad/s. Such a capability meets a requirement for the use of storage rings to look for an intrinsic electric dipole moment of charged particles.
  •  
36.
  • Saleev, A., et al. (författare)
  • Spin tune mapping as a novel tool to probe the spin dynamics in storage rings
  • 2017
  • Ingår i: Physical Review Accelerators and Beams. - : American Physical Society. - 2469-9888. ; 20:7
  • Tidskriftsartikel (refereegranskat)abstract
    • Precision experiments, such as the search for electric dipole moments of charged particles using storage rings, demand for an understanding of the spin dynamics with unprecedented accuracy. The ultimate aim is to measure the electric dipole moments with a sensitivity up to 15 orders in magnitude better than the magnetic dipole moment of the stored particles. This formidable task requires an understanding of the background to the signal of the electric dipole from rotations of the spins in the spurious magnetic fields of a storage ring. One of the observables, especially sensitive to the imperfection magnetic fields in the ring is the angular orientation of stable spin axis. Up to now, the stable spin axis has never been determined experimentally, and in addition, the JEDI collaboration for the first time succeeded to quantify the background signals that stem from false rotations of the magnetic dipole moments in the horizontal and longitudinal imperfection magnetic fields of the storage ring. To this end, we developed a new method based on the spin tune response of a machine to artificially applied longitudinal magnetic fields. This novel technique, called spin tune mapping, emerges as a very powerful tool to probe the spin dynamics in storage rings. The technique was experimentally tested in 2014 using polarized deuterons stored in the cooler synchrotron COSY, and for the first time, the angular orientation of the stable spin axis at two different locations in the ring has been determined to an unprecedented accuracy of better than 2.8 mu rad.
  •  
37.
  • Blondel, A., et al. (författare)
  • The SuperFGD Prototype charged particle beam tests
  • 2020
  • Ingår i: Journal of Instrumentation. - : IOP PUBLISHING LTD. - 1748-0221. ; 15:12
  • Tidskriftsartikel (refereegranskat)abstract
    • A novel scintillator detector, the SuperFGD, has been selected as the main neutrino target for an upgrade of the T2K experiment ND280 near detector. The detector design will allow nearly 47r coverage for neutrino interactions at the near detector and will provide lower energy thresholds, significantly reducing systematic errors for the experiment. The SuperFGD is made of optically-isolated scintillator cubes of size 10 x 10 x 10 mm(3), providing the required spatial and energy resolution to reduce systematic uncertainties for future T2K runs. The SuperFGD for T2K will have close to two million cubes in a 1920 x 560 x 1840 mm(3) volume. A prototype made of 24 x 8 x 48 cubes was tested at a charged particle beamline at the CERN PS facility. The SuperFGD Prototype was instrumented with readout electronics similar to the future implementation for T2K. Results on electronics and detector response are reported in this paper, along with a discussion of the 3D reconstruction capabilities of this type of detector. Several physics analyses with the prototype data are also discussed, including a study of stopping protons.
  •  
38.
  • Guidoboni, G., et al. (författare)
  • Connection between zero chromaticity and long in-plane polarization lifetime in a magnetic storage ring
  • 2018
  • Ingår i: Physical Review Accelerators and Beams. - : American Physical Society. - 2469-9888. ; 21:2
  • Tidskriftsartikel (refereegranskat)abstract
    • In this paper, we demonstrate the connection between a magnetic storage ring with additional sextupole fields set so that the x and y chromaticities vanish and the maximizing of the lifetime of in-plane polarization (IPP) for a 0.97-GeV/c deuteron beam. The IPP magnitude was measured by continuously monitoring the down-up scattering asymmetry (sensitive to sideways polarization) in an in-beam, carbontarget polarimeter and unfolding the precession of the IPP due to the magnetic anomaly of the deuteron. The optimum operating conditions for a long IPP lifetime were made by scanning the field of the storage ring sextupole magnet families while observing the rate of IPP loss during storage of the beam. The beam was bunched and electron cooled. The IPP losses appear to arise from the change of the orbit circumference, and consequently the particle speed and spin tune, due to the transverse betatron oscillations of individual particles in the beam. The effects of these changes are canceled by an appropriate sextupole field setting.
  •  
39.
  • Zurek, M, et al. (författare)
  • Assessing the relationship between lung density and function with oxygen-enhanced magnetic resonance imaging in a mouse model of emphysema
  • 2016
  • Ingår i: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203 .- 1932-6203. ; 11:3
  • Tidskriftsartikel (refereegranskat)abstract
    • This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Purpose: A magnetic resonance imaging method is presented that allows for the simultaneous assessment of oxygen delivery, oxygen uptake, and parenchymal density. The technique is applied to a mouse model of porcine pancreatic elastase (PPE) induced lung emphysema in order to investigate how structural changes affect lung function. Method: Nine-week-old female C57BL6 mice were instilled with saline or PPE at days 0 and 7. At day 19, oxygen delivery, oxygen uptake, and lung density were quantified from T1 and proton-density measurements obtained via oxygen-enhanced magnetic resonance imaging (OE-MRI) using an ultrashort echo-time imaging sequence. Subsequently, the lungs were sectioned for histological observation. Blood-gas analyses and pulmonary functional tests via FlexiVent were performed in separate cohorts. Principal Findings: PPE-challenged mice had reduced density when assessed via MRI, consistent with the parenchyma loss observed in the histology sections, and an increased lung compliance was detected via FlexiVent. The oxygenation levels, as assessed via the blood-gas analysis, showed no difference between PPE-challenged animals and control. This finding was mirrored in the global MRI assessments of oxygen delivery and uptake, where the changes in relaxation time indices were matched between the groups. The heterogeneity of the same parameters however, were increased in PPE-challenged animals. When the oxygenation status was investigated in regions of varying density, a reduced oxygen-uptake was found in low-density regions of PPE-challenged mice. In high-density regions the uptake was higher than that of regions of corresponding density in control animals. The oxygen delivery was proportional to the oxygen uptake in both groups. Conclusions: The proposed method allowed for the regional assessment of the relationship between lung density and two aspects of lung function, the oxygen delivery and uptake. When compared to global indices of lung function, an increased sensitivity for detecting heterogeneous lung disorders was found. This indicated that the technique has potential for early detection of lung dysfunction-before global changes occur.
  •  
40.
  • Beverborg, Niels Grote, et al. (författare)
  • Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy
  • 2021
  • Ingår i: Nature Communications. - Stockholm : Karolinska Institutet, Dept of Cell and Molecular Biology. - 2041-1723.
  • Tidskriftsartikel (refereegranskat)abstract
    • Heart failure (HF) is a major cause of morbidity and mortality worldwide, highlighting an urgent need for novel treatment options, despite recent improvements. Aberrant Ca2+ handling is a key feature of HF pathophysiology. Restoring the Ca2+ regulating machinery is an attractive therapeutic strategy supported by genetic and pharmacological proof of concept studies. Here, we study antisense oligonucleotides (ASOs) as a therapeutic modality, interfering with the PLN/SERCA2a interaction by targeting Pln mRNA for downregulation in the heart of murine HF models. Mice harboring the PLN R14del pathogenic variant recapitulate the human dilated cardiomyopathy (DCM) phenotype; subcutaneous administration of PLN-ASO prevents PLN protein aggregation, cardiac dysfunction, and leads to a 3-fold increase in survival rate. In another genetic DCM mouse model, unrelated to PLN (Cspr3/Mlp−/−), PLN-ASO also reverses the HF phenotype. Finally, in rats with myocardial infarction, PLN-ASO treatment prevents progression of left ventricular dilatation and improves left ventricular contractility. Thus, our data establish that antisense inhibition of PLN is an effective strategy in preclinical models of genetic cardiomyopathy as well as ischemia driven HF.
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41.
  •  
42.
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43.
  • Dieball, A., et al. (författare)
  • Far-ultraviolet observation of the globular cluster NGC 6397
  • 2017
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 469:1, s. 267-277
  • Tidskriftsartikel (refereegranskat)abstract
    • We present an observational far-ultraviolet (FUV) and near-ultraviolet (NUV) study of the core region of the globular cluster (GC) NGC 6397. The observations were obtained with the Space Telescope Imaging Spectrograph (STIS, FUV) and the Wide Field Camera 3 (NUV) on board the Hubble Space Telescope. Here, we focus on the UV-bright stellar populations such as blue stragglers (BSs), white dwarfs (WDs) and cataclysmic variables (CVs). We present the first FUV - NUV colour-magnitude diagram (CMD) for this cluster. To support our classification of the stellar populations, we compare our FUV - NUV CMD with optical data from the ACS Survey of Galactic Globular Clusters. The FUV - NUV CMD indicates 16 sources located in the WD area, and 10 BSs within the 25 x 25 arcsec(2) of the STIS FUV data. 18 Chandra X-ray sources are located within the FUV field of view. 13 of those have an NUV counterpart, of which 9 sources also have an FUV counterpart. Out of those, five sources are previously suggested CVs, and indeed, all five are located in the WD/CV region in our FUV - NUV CMD. Another CV has only an FUV but no NUV counterpart. We also detect an NUV (but no FUV) counterpart to the millisecond pulsar (MSP) located in the core of this cluster. The NUV light curves of the CVs and MSP show flickering behaviour typical of CVs. We found that the BSs and CVs are the most centrally concentrated populations. This might be an effect of mass segregation or it might indicate the preferred birth place of BSs and CVs via dynamical interactions in the dense core region of GCs. Horizontal branch stars are the least centrally concentrated population and absent in the innermost area of the core.
  •  
44.
  • Marturi, Naresh, et al. (författare)
  • Towards advanced robotic manipulation for nuclear decommissioning: A pilot study on tele-operation and autonomy
  • 2016
  • Ingår i: IEEE International Conference on Robotics and Automation for Humanitarian Applications (RAHA). - 9781509052035
  • Konferensbidrag (refereegranskat)abstract
    • We present early pilot-studies of a new international project, developing advanced robotics to handle nuclear waste. Despite enormous remote handling requirements, there has been remarkably little use of robots by the nuclear industry. The few robots deployed have been directly teleoperated in rudimentary ways, with no advanced control methods or autonomy. Most remote handling is still done by an aging workforce of highly skilled experts, using 1960s style mechanical Master-Slave devices. In contrast, this paper explores how novice human operators can rapidly learn to control modern robots to perform basic manipulation tasks; also how autonomous robotics techniques can be used for operator assistance, to increase throughput rates, decrease errors, and enhance safety. We compare humans directly teleoperating a robot arm, against human-supervised semi-autonomous control exploiting computer vision, visual servoing and autonomous grasping algorithms. We show how novice operators rapidly improve their performance with training; suggest how training needs might scale with task complexity; and demonstrate how advanced autonomous robotics techniques can help human operators improve their overall task performance. An additional contribution of this paper is to show how rigorous experimental and analytical methods from human factors research, can be applied to perform principled scientific evaluations of human test-subjects controlling robots to perform practical manipulative tasks.
  •  
45.
  • Webster, Christopher R., et al. (författare)
  • Background levels of methane in Mars' atmosphere show strong seasonal variations
  • 2018
  • Ingår i: Science. - : American Association for the Advancement of Science. - 0036-8075 .- 1095-9203. ; 360:6393, s. 1093-1096
  • Tidskriftsartikel (refereegranskat)abstract
    • Variable levels of methane in the martian atmosphere have eluded explanation partly because the measurements are not repeatable in time or location. We report in situ measurements at Gale crater made over a 5-year period by the Tunable Laser Spectrometer on the Curiosity rover. The background levels of methane have a mean value 0.41 ± 0.16 parts per billion by volume (ppbv) (95% confidence interval) and exhibit a strong, repeatable seasonal variation (0.24 to 0.65 ppbv). This variation is greater than that predicted from either ultraviolet degradation of impact-delivered organics on the surface or from the annual surface pressure cycle. The large seasonal variation in the background and occurrences of higher temporary spikes (~7 ppbv) are consistent with small localized sources of methane released from martian surface or subsurface reservoirs.
  •  
46.
  • Zurek, Birte, et al. (författare)
  • TRIM27 Negatively Regulates NOD2 by Ubiquitination and Proteasomal Degradation
  • 2012
  • Ingår i: PLOS ONE. - San fransisco, USA : Public Library of Science. - 1932-6203. ; 7:7
  • Tidskriftsartikel (refereegranskat)abstract
    • NOD2, the nucleotide-binding domain and leucine-rich repeat containing gene family (NLR) member 2 is involved in mediating antimicrobial responses. Dysfunctional NOD2 activity can lead to severe inflammatory disorders, but the regulation of NOD2 is still poorly understood. Recently, proteins of the tripartite motif (TRIM) protein family have emerged as regulators of innate immune responses by acting as E3 ubiquitin ligases. We identified TRIM27 as a new specific binding partner for NOD2. We show that NOD2 physically interacts with TRIM27 via the nucleotide-binding domain, and that NOD2 activation enhances this interaction. Dependent on functional TRIM27, ectopically expressed NOD2 is ubiquitinated with K48-linked ubiquitin chains followed by proteasomal degradation. Accordingly, TRIM27 affects NOD2-mediated pro-inflammatory responses. NOD2 mutations are linked to susceptibility to Crohns disease. We found that TRIM27 expression is increased in Crohns disease patients, underscoring a physiological role of TRIM27 in regulating NOD2 signaling. In HeLa cells, TRIM27 is partially localized in the nucleus. We revealed that ectopically expressed NOD2 can shuttle to the nucleus in a Walker A dependent manner, suggesting that NOD2 and TRIM27 might functionally cooperate in the nucleus. We conclude that TRIM27 negatively regulates NOD2-mediated signaling by degradation of NOD2 and suggest that TRIM27 could be a new target for therapeutic intervention in NOD2-associated diseases.
  •  
47.
  • Zurek, M., et al. (författare)
  • Accurate T-1 Mapping for Oxygen-Enhanced MRI in the Mouse Lung Using a Segmented Inversion-Recovery Ultrashort Echo-Time Sequence
  • 2014
  • Ingår i: Magnetic Resonance in Medicine. - : Wiley. - 1522-2594 .- 0740-3194. ; 71:6, s. 2180-2185
  • Tidskriftsartikel (refereegranskat)abstract
    • PurposeA segmented inversion-recovery module combined with the 2D ultrashort echo time radial technique is proposed that allows accurate pixel level T-1 mapping of mouse lung in vivo. MethodsNumerical simulations were performed to estimate T-1 measurement accuracy and precision versus flip angle and signal-to-noise ratio. Phantom measurements were used for protocol validation, where the segmented inversion-recovery ultrashort echo-time sequence was compared with the reference technique (inversion-recovery rapid acquisition with refocused echoes). The in vivo experiments were carried out on free-breathing C57 mice (n = 10), breathing first air and then oxygen. ResultsThe simulations demonstrated the high potential of the technique for accurate and precise T-1 assessment. Phantom experiments showed good agreement for T-1 values measured with segmented inversion-recovery ultrashort echo-time and the reference technique. The in vivo experiment demonstrated the utility of the technique in oxygen-enhanced assessment, where small T-1 changes were detected with high precision. ConclusionSegmented inversion-recovery ultrashort echo-time provides accurate, high resolution T-1 mapping of the lung parenchyma. Magn Reson Med 71:2180-2185, 2014. (c) 2013 Wiley Periodicals, Inc.
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48.
  • Zurek, Monika, et al. (författare)
  • Assessing Sustainable Food and Nutrition Security of the EU Food System-An Integrated Approach
  • 2018
  • Ingår i: Sustainability. - : MDPI AG. - 2071-1050. ; 10:11
  • Tidskriftsartikel (refereegranskat)abstract
    • Steering the EU food system towards a sustainability transformation requires a vast and actionable knowledge base available to a range of public and private actors. Few have captured this complexity by assessing food systems from a multi-dimensional and multi-level perspective, which would include (1) nutrition and diet, environmental and economic outcomes together with social equity dimensions and (2) system interactions across country, EU and global scales. This paper addresses this gap in food systems research and science communication by providing an integrated analytical approach and new ways to communicate this complexity outside science. Based on a transdisciplinary science approach with continuous stakeholder input, the EU Horizon2020 project 'Metrics, Models and Foresight for European SUStainable Food And Nutrition Security' (SUSFANS) developed a five-step process: Creating a participatory space; designing a conceptual framework of the EU food system; developing food system performance metrics; designing a modelling toolbox and developing a visualization tool. The Sustainable Food and Nutrition-Visualizer, designed to communicate complex policy change-impacts and trade-off questions, enables an informed debate about trade-offs associated with options for change among food system actors as well as in the policy making arena. The discussion highlights points for further research related to indicator development, reach of assessment models, participatory processes and obstacles in science communication.
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