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Träfflista för sökning "LAR1:gu ;pers:(Skoog Ingmar 1954);pers:(Östling Svante 1953);mspu:(article);pers:(Hällström Tore 1935);srt2:(2020)"

Search: LAR1:gu > Skoog Ingmar 1954 > Östling Svante 1953 > Journal article > Hällström Tore 1935 > (2020)

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  • Najar, Jenna, et al. (author)
  • Reproductive period and dementia: A 44-year longitudinal population study of Swedish women
  • 2020
  • In: Alzheimers & Dementia. - : Wiley. - 1552-5260 .- 1552-5279. ; 16:8, s. 1153-1163
  • Journal article (peer-reviewed)abstract
    • Introduction: Longitudinal studies examining the effect of endogenous estrogens on dementia risk are needed to understand why women have higher dementia incidence than men after age 85. Methods: A population-based sample of women with natural menopause (N = 1364) from Gothenburg, Sweden, was followed from 1968-2012. Information on endogenous estrogens (age at menarche and menopause, number of pregnancies, and months of breastfeeding) was obtained from interviews in 1968-1992. Dementia was diagnosed according to established criteria based on information from neuropsychiatric examinations and close informant interviews. Results: We found that longer reproductive period was associated with increased risk of dementia (hazard ratio [HR] per year 1.06, 95% confidence interval [CI] 1.03-1.20) and Alzheimer's disease (AD) (1.06, 1.02-1.11), particularly for those with dementia (1.10, 1.04-1.17) and AD (1.15, 1.06-1.26) onset after age 85. Discussion: These results may explain why women have higher dementia incidence compared to men after age 85, the age with the highest number of dementia cases.
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journal article  (1)Undo refine
Type of content
peer-reviewed (1)
Author/Editor
Waern, Margda, 1955 (1)
Skoog, Ingmar, 1... (1)Undo refine
Kern, Silke (1)
Östling, Svante,... (1)Undo refine
Zettergren, Anna, 19 ... (1)
Wetterberg, Hanna (1)
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University
University of Gothenburg (1)
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English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year
2020 (1)Undo refine

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