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- Linhult, M., et al.
(author)
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Affinity ligands for industrial protein purification
- 2005
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In: Protein peptide letters. - : Bentham Science Publishers Ltd.. - 0929-8665 .- 1875-5305. ; 12:4, s. 305-310
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Research review (peer-reviewed)abstract
- Significant efforts are put into the design of large-scale purification processes of proteins due to great demands regarding cost efficiency and safety. In order to design an effective purification scheme the unit operations need to be reduced to a minimum. In this review we are discussing proteinaceous ligands as well as small synthetic mimics for use in affinity chromatography for large-scale applications. Different advantages as well as drawbacks of the two approaches are outlined.
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