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Search: WFRF:(Gotic M) > (2004)

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  • Lazarevic, Vladimir Lj, et al. (author)
  • A novel t(2;17) in transformation of essential thrombocythemia to acute myelocytic leukemia.
  • 2004
  • In: Cancer Genetics and Cytogenetics. - 0165-4608 .- 1873-4456. ; 148:1, s. 77-9
  • Journal article (peer-reviewed)abstract
    • A transformation of essential thrombocythemia to acute myelocytic leukemia (AML), myelodysplastic syndrome, or agnogenic myelocytic metaplasia is a relatively rare event. It occurs in 1%-4.5% of all patients with either treated or untreated essential thrombocythemia. Cytogenetic changes in the transformation to AML are common. We report the case of a patient treated for essential thrombocythemia with hydroxyurea for 49 months. He developed AML with a t(2;17), which to our knowledge has not been described in the literature.
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