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Search: WFRF:(McGregor Keith)

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  • Chastin, Sebastien, et al. (author)
  • Joint association between accelerometry-measured daily combination of time spent in physical activity, sedentary behaviour and sleep and all-cause mortality : A pooled analysis of six prospective cohorts using compositional analysis
  • 2021
  • In: British Journal of Sports Medicine. - : BMJ. - 0306-3674 .- 1473-0480. ; 55:22, s. 1277-1285
  • Journal article (peer-reviewed)abstract
    • OBJECTIVE: To examine the joint associations of daily time spent in different intensities of physical activity, sedentary behaviour and sleep with all-cause mortality.METHODS: Federated pooled analysis of six prospective cohorts with device-measured time spent in different intensities of physical activity, sedentary behaviour and sleep following a standardised compositional Cox regression analysis.PARTICIPANTS: 130 239 people from general population samples of adults (average age 54 years) from the UK, USA and Sweden.MAIN OUTCOME: All-cause mortality (follow-up 4.3-14.5 years).RESULTS: Studies using wrist and hip accelerometer provided statistically different results (I2=92.2%, Q-test p<0.001). There was no association between duration of sleep and all-cause mortality, HR=0.96 (95% CI 0.67 to 1.12). The proportion of time spent in moderate to vigorous physical activity was significantly associated with lower risk of all-cause mortality (HR=0.63 (95% CI 0.55 to 0.71) wrist; HR=0.93 (95% CI 0.87 to 0.98) hip). A significant association for the ratio of time spent in light physical activity and sedentary time was only found in hip accelerometer-based studies (HR=0.5, 95% CI 0.42 to 0.62). In studies based on hip accelerometer, the association between moderate to vigorous physical activity and mortality was modified by the balance of time spent in light physical activity and sedentary time.CONCLUSION: This federated analysis shows a joint dose-response association between the daily balance of time spent in physical activity of different intensities and sedentary behaviour with all-cause mortality, while sleep duration does not appear to be significant. The strongest association is with time spent in moderate to vigorous physical activity, but it is modified by the balance of time spent in light physical activity relative to sedentary behaviour.
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  • Graham, Ian, et al. (author)
  • European guidelines on cardiovascular disease prevention in clinical practice: full text. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of nine societies and by invited experts).
  • 2007
  • In: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology. - : Oxford University Press (OUP). - 1741-8267. ; 14 Suppl 2
  • Journal article (peer-reviewed)abstract
    • Other experts who contributed to parts of the guidelines: Edmond Walma, Tony Fitzgerald, Marie Therese Cooney, Alexandra Dudina European Society of Cardiology (ESC) Committee for Practice Guidelines (CPG): Alec Vahanian (Chairperson), John Camm, Raffaele De Caterina, Veronica Dean, Kenneth Dickstein, Christian Funck-Brentano, Gerasimos Filippatos, Irene Hellemans, Steen Dalby Kristensen, Keith McGregor, Udo Sechtem, Sigmund Silber, Michal Tendera, Petr Widimsky, Jose Luis Zamorano Document reviewers: Irene Hellemans (CPG Review Co-ordinator), Attila Altiner, Enzo Bonora, Paul N. Durrington, Robert Fagard, Simona Giampaoli, Harry Hemingway, Jan Hakansson, Sverre Erik Kjeldsen, Mogens Lytken Larsen, Giuseppe Mancia, Athanasios J. Manolis, Kristina Orth-Gomer, Terje Pedersen, Mike Rayner, Lars Ryden, Mario Sammut, Neil Schneiderman, Anton F. Stalenhoef, Lale Tokgözoglu, Olov Wiklund, Antonis Zampelas
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  • Result 1-10 of 15
Type of publication
journal article (13)
Type of content
peer-reviewed (13)
Author/Editor
Zamorano, Jose Luis (12)
McGregor, Keith (12)
Tendera, Michal (11)
Widimsky, Petr (11)
Dean, Veronica (11)
Filippatos, Gerasimo ... (11)
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De Caterina, Raffael ... (11)
Dickstein, Kenneth (11)
Silber, Sigmund (11)
Sechtem, Udo (11)
Funck-Brentano, Chri ... (11)
Vahanian, Alec (11)
Hellemans, Irene (11)
Camm, John (10)
Kristensen, Steen Da ... (8)
Priori, Silvia G (8)
Blomström-Lundqvist, ... (5)
De Backer, Guy (5)
Fagard, Robert (5)
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Blanc, Jean-Jacques (5)
Oto, Ali (5)
Ruilope, Luis (5)
Linde, Cecilia (4)
Drexler, Helmut (4)
Auricchio, Angelo (4)
Gasparini, Maurizio (4)
Vardas, Panos E (4)
Brignole, Michele (4)
Cleland, John (4)
Sutton, Richard (4)
Mancia, Giuseppe (4)
Le Heuzey, Jean-Yves (4)
Daubert, Jean-Claude (4)
Manolis, Athanasios ... (4)
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Laurent, Stephane (3)
Lip, Gregory Y H (3)
Lindholm, Lars H (3)
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Dalby Kristensen, St ... (3)
Dominiczak, Anna (3)
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Medical and Health Sciences (3)

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