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Search: WFRF:(Traherne James A) > (2014)

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  • Næss, Sigrid, et al. (author)
  • Refinement of the MHC risk map in a scandinavian primary sclerosing cholangitis population
  • 2014
  • In: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 9:12
  • Journal article (peer-reviewed)abstract
    • Genetic variants within the major histocompatibility complex (MHC) represent the strongest genetic susceptibility factors for primary sclerosing cholangitis (PSC). Identifying the causal variants within this genetic complex represents a major challenge due to strong linkage disequilibrium and an overall high physical density of candidate variants. We aimed to refine the MHC association in a geographically restricted PSC patient panel.
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