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  • Ibrahem, Ismail, et al. (author)
  • Enantioselective Organocatalytic Hydrophosphination of α,β-Unsaturated Aldehydes
  • 2007
  • In: Angewandte Chemie International Edition. - : Wiley. - 1433-7851 .- 1521-3773. ; 46:24, s. 4507-4510
  • Journal article (peer-reviewed)abstract
    • Keeping it simple: Optically active phosphine derivatives can be obtained in high yields and in up to 99% ee by using simple chiral amines to catalyze the hydrophosphination of α,β-unsaturated aldehydes (see scheme, green sphere = chiral group). The synthetic utility of this highly chemo- and enantioselective transformation was exemplified by the one-pot asymmetric synthesis of β-phosphine oxide acids.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Eriksson, Lars (1)
Ibrahem, Ismail (1)
Córdova, Armando (1)
Himo, Fahmi (1)
Veselý, Jan (1)
Rios, Ramón (1)
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Hammar, Peter (1)
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University
Royal Institute of Technology (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year

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