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  • Spasokukotskaja, T., et al. (author)
  • Deoxycytidine is salvaged not only into DNA but also into phospholipid precursors
  • 1988
  • In: Biochemical and Biophysical Research Communications - BBRC. - : Elsevier. - 0006-291X .- 1090-2104. ; 155:2, s. 923-929
  • Journal article (peer-reviewed)abstract
    • Deoxycytidine metabolism was investigated in light density human tonsillar lymphocytes using 5-3H-deoxycytidine as extracellular precursor. A significant portion of the deoxycytidine (more than 50% of ethanol soluble pool) was found to incorporate into dCDP-choline and dCDP-ethanolamine beside the well-known pathway i.e. incorporation into DNA in form of dCMP and dTMP. Hydroxyurea increased the labeling of the deoxyliponucleotides from 5-3H-deoxycytidine in spite of its inhibition of DNA synthesis.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Spyrou, Giannis (1)
Staub, M (1)
Spasokukotskaja, T. (1)
University
Linköping University (1)
Language
English (1)
Year
1988 (1)

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