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  • Nyhlin, Nils, et al. (author)
  • Microscopic colitis : a common and an easily overlooked cause of chronic diarrhoea
  • 2008
  • In: European journal of internal medicine. - Amsterdam : Elsevier. - 0953-6205 .- 1879-0828. ; 19:3, s. 181-186
  • Research review (peer-reviewed)abstract
    • Microscopic colitis, comprising collagenous colitis and lymphocytic colitis, is characterised clinically by chronic watery diarrhoea, a macroscopically normal colonic mucosa where diagnostic histopathological features are seen on microscopic examination. The annual incidence of each disorder is 4–6/100,000 inhabitants, with a peak incidence in 60–70 year old individuals and a noticeable female predominance in collagenous colitis. The aetiology is unknown. Abdominal pain, weight loss, fatigue, and faecal incontinence are common symptoms in addition to chronic diarrhoea that impair the health-related quality of life of the patient. There is an association to other autoimmune disorders such as celiac disease, diabetes mellitus, thyroid disorders and arthritis. Budesonide is the best-documented short-term treatment, but the optimal long-term strategy needs further study. The long-term prognosis is good and the risk of complications including colonic cancer is low.
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Type of publication
research review (1)
Type of content
peer-reviewed (1)
Author/Editor
Tysk, Curt (1)
Nyhlin, Nils (1)
Bohr, Johan (1)
Eriksson, Sune (1)
University
Örebro University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year

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