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- Jalkanen, Ville, 1978-
(author)
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Handheld resonance sensor instrumentation towards faster diagnosis of prostate cancer : stiffness measurements on a soft tissue phantom
- 2009
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In: IFMBE Proceedings of the World Congress on Medical Physics and Biomedical Engineering. - Heidelberg : Springer. ; , s. 808-811
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Conference paper (peer-reviewed)abstract
- Prostate cancer is the most common type of cancer among men. Standard methods for detecting and diagnosing prostate cancer are not sensitive enough. Radical prostatectomy is a procedure where the prostate is removed as a treatment for prostate cancer. Objectively measured prostate stiffness could be a clinical marker for prostate cancer and this could be accomplished with a stiffness sensitive resonance sensor. A future handheld pen-like resonance sensor instrument could be a valuable clinical tool for locating cancer during radical prostatectomy surgery and thus aid in the diagnosis and treatment. The aim of this study was to evaluate the concept of a handheld resonance sensor for stiffness measurements on a soft tissue phantom. For a handheld resonance sensor set-up the impression depth and speed of the sensor tip into the tissue are unknown. A theoretical model was derived to show that a stiffness sensitive parameter can be obtained independent of the impression depth and the impression speed. The theoretical result was verified on a soft tissue phantom made of gelatin with a silicon tumor inclusion. These results were promising for further studies and development of a handheld instrument towards faster diagnosis of prostate cancer.
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